The brain: is the organ located in the head and serves as the center of the nervous system in all vertebrate. The brain is the most complex organ in a vertebrate's body and is close to the sensory organs for senses such as vision.
The coronavirus SARS-CoV-2 has led to a worldwide pandemic. Beside respiratory symptoms, infected people may develop neurologic dysfunctions such as loss of smell and taste, also seizures, a...
Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
Date: April 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Abnormal accumulation of misfolded tau protein in filaments characterizes more than 20 neurodegenerative diseases—c...
Date: March 24, 2022 Time: 8:00am (PST), 11:00am (EST), 4:00pm (GMT) Key to precision oncology is the development of expert databases that organize and standardize information on cancer-rel...
Date: March 23, 2021 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEDT) In this presentation, Dr. Middleton will review the development and deployment of large-scale saliva-based COVID-19 test...
Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded proteins. The histopathological hallmark of synucleinopathies is the deposition of É‘-...
Behavior in complex environments requires decisions that flexibly combine stimulus representations with context, goals, and memory. Two key aspects of such cognitive flexibility are the retr...
Major depression (MDD) is a common psychiatric condition and a leading cause of disability worldwide. While psychotherapy and pharmacotherapy are effective treatments for the majority of peo...
Treatment-resistant depression is an immense source of disability and suffering, and represents a major unmet clinical need for innovative and effective therapies. Deep brain stimulation tri...
Neuroscience is experiencing an exciting era of integrating novel materials and tools to record neural activity made possible through significant advances in materials science, electrical en...
Brain wave synchronization, also called neuronal coherence, is a fundamental mechanism of communication in the brain, where synchronized field potentials coordinate synaptic and spiking even...
Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in our society, no...
We are in critical need of targeted and individualized treatments for mental health disorders, which affect nearly 50% of Americans during our lifetimes. Brain stimulation treatments, includ...
Detection of neural signatures related to pathological behavioral states could enable adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for neurologic...
While our lives unfold over time, weaving dynamic information into continuous experience, our memories are organized as discrete events. Detection of cognitive boundaries is critical for seg...
We present intracranial recordings that tap into some elementary components of linguistic meaning, with implications for our understanding of sentence processing and the distribution of conc...
Patients with implanted neural devices offer researchers unique opportunities to study the basic workings of the human brain. This is made possible by patients undergoing epilepsy monitoring...
The ability of light sheet microscopy to interrogate organoids, whole brain, and systems in 3D enables the study of complex neurological pathways, vasculature and disease models in unique wa...
NanoString has started an ambitious project called the "Spatial Organ Atlas." The goal of this initiative is to map the architecture of tissues with spatially resolved whole transc...
Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
Date: November 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) Analysis of SARS-CoV-2–specific T cells is important to understand their role during acute disease and in long-term protection...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...
The coronavirus SARS-CoV-2 has led to a worldwide pandemic. Beside respiratory symptoms, infected people may develop neurologic dysfunctions such as loss of smell and taste, also seizures, a...
Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
Date: April 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Abnormal accumulation of misfolded tau protein in filaments characterizes more than 20 neurodegenerative diseases—c...
Date: March 24, 2022 Time: 8:00am (PST), 11:00am (EST), 4:00pm (GMT) Key to precision oncology is the development of expert databases that organize and standardize information on cancer-rel...
Date: March 23, 2021 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEDT) In this presentation, Dr. Middleton will review the development and deployment of large-scale saliva-based COVID-19 test...
Several age-related neurodegenerative disorders are characterized by the deposition of aberrantly folded proteins. The histopathological hallmark of synucleinopathies is the deposition of É‘-...
Behavior in complex environments requires decisions that flexibly combine stimulus representations with context, goals, and memory. Two key aspects of such cognitive flexibility are the retr...
Major depression (MDD) is a common psychiatric condition and a leading cause of disability worldwide. While psychotherapy and pharmacotherapy are effective treatments for the majority of peo...
Treatment-resistant depression is an immense source of disability and suffering, and represents a major unmet clinical need for innovative and effective therapies. Deep brain stimulation tri...
Neuroscience is experiencing an exciting era of integrating novel materials and tools to record neural activity made possible through significant advances in materials science, electrical en...
Brain wave synchronization, also called neuronal coherence, is a fundamental mechanism of communication in the brain, where synchronized field potentials coordinate synaptic and spiking even...
Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in our society, no...
We are in critical need of targeted and individualized treatments for mental health disorders, which affect nearly 50% of Americans during our lifetimes. Brain stimulation treatments, includ...
Detection of neural signatures related to pathological behavioral states could enable adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for neurologic...
While our lives unfold over time, weaving dynamic information into continuous experience, our memories are organized as discrete events. Detection of cognitive boundaries is critical for seg...
We present intracranial recordings that tap into some elementary components of linguistic meaning, with implications for our understanding of sentence processing and the distribution of conc...
Patients with implanted neural devices offer researchers unique opportunities to study the basic workings of the human brain. This is made possible by patients undergoing epilepsy monitoring...
The ability of light sheet microscopy to interrogate organoids, whole brain, and systems in 3D enables the study of complex neurological pathways, vasculature and disease models in unique wa...
NanoString has started an ambitious project called the "Spatial Organ Atlas." The goal of this initiative is to map the architecture of tissues with spatially resolved whole transc...
Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
Date: November 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) Analysis of SARS-CoV-2–specific T cells is important to understand their role during acute disease and in long-term protection...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...
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