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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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NOV 25, 2019Drug Discovery & Development
Researchers have long known that the cause behind Alexander disease is a genetic culprit—mainly a mutation leading ...Written By: Nouran AminNOV 24, 2019Cell & Molecular Biology
Proteins are critical to biology, and are generated by vital, ancient cellular structures called ribosomes.Written By: Carmen LeitchNOV 18, 2019Drug Discovery & Development
Sickle cell disease affects approximately 100,000 Americans. Currently, the only available cure for the disease is a cos ...Written By: Annie LennonNOV 06, 2019Drug Discovery & Development
Scientists at Karolinska Institutet in Sweden were able to pinpoint 10 tumor-specific potential drug targets for the fat ...Written By: Nouran AminNOV 01, 2019Chemistry & Physics
In a recent study, a group of biomedical researchers at Michigan State University developed a new platform for tweaking ...Written By: Daniel DuanOCT 23, 2019Immunology
Delivering gluten to the body in a friendly, harmless package may be the way for people with celiac disease to finally h ...Written By: Kara MarkerOCT 21, 2019Technology
Researchers have developed a software system that converts cell phones into augmented reality (AR) portals that allows u ...Written By: Nouran AminOCT 15, 2019Microbiology
We produce several liters of mucus every day to cover more than 200 square meters in the human body.Written By: Carmen LeitchOCT 13, 2019Microbiology
Now a team of scientists has found a molecule in human breast milk that may reduce the risk of illness and disease.Written By: Carmen LeitchOCT 12, 2019Immunology
The body’s own immune cells may be the common denominator in Alzheimer’s disease. In a new study of the rela ...Written By: Kara MarkerOCT 07, 2019Clinical & Molecular DX
Hypertension is also known as high blood pressure is a serious condition. According to the Centers for Disease Cont ...Written By: Nupur SrivastavaSEP 29, 2019Cell & Molecular Biology
Understanding how and when and why certain genes are or are not active is a critical aspect of biomedical research.Written By: Carmen LeitchSEP 17, 2019Cannabis Sciences
This is an introduction into cannabis genetics including chromosome number, genetic variation leading to expression diff ...Written By: Mauri BrueggemanSEP 03, 2019Microbiology
While attention has been brought to the issue and some progress has been made, hospital-acquired infections are still a ...Written By: Carmen LeitchAUG 18, 2019Cell & Molecular Biology
As tissues grow in a developing embryo, they have to fold in the right way to create the proper structures.Written By: Carmen LeitchJUL 22, 2019Plants & Animals
Getting a blood sample from a massive whale shark can be particularly challenging and would typically require administer ...Written By: Anthony BouchardJUL 11, 2019Health & Medicine
The Pennsylvania Department of Health added anxiety disorders and Tourette's syndrome to a rather short list of heal ...JUL 09, 2019Genetics & Genomics
Agriculture has valued the production of a handful of staple foods, and genetic diversity among our crops has declined, ...Written By: Carmen LeitchJUL 09, 2019Drug Discovery & Development
Uveal melanoma is a rare and aggressive type of melanoma that targets the eye and affects an estimated 2,500 people in t ...Written By: Nouran AminJUN 18, 2019Drug Discovery & Development
Researchers from the University of Sheffield in collaboration with Glasgow-based biotech company Mironid, have developed ...Written By: Nouran AminJUN 15, 2019Cell & Molecular Biology
In RA, cells of the immune system mistakenly attack the joints, and cause the painful inflammation that is a hallmark of ...Written By: Carmen LeitchJUN 07, 2019Cell & Molecular Biology
Researchers were surprised to find that neurons aren't the only aged cells in the body.Written By: Carmen LeitchJUN 07, 2019Health & Medicine
A stem cell, by definition, must be able to self-replicate to make more stem cells and to differentiate into a matu ...Written By: Dena ArutaMAY 24, 2019Cancer
Castration-resistant prostate cancer (CRPC) is a particularly aggressive form of prostate cancer. Although the standard ...Written By: Kathryn DeMuth Sullivan
NOV 25, 2019
Drug Discovery & Development
Researchers have long known that the cause behind Alexander disease is a genetic culprit—mainly a mutation leading
...
Written By:
Nouran Amin
NOV 24, 2019
Cell & Molecular Biology
Proteins are critical to biology, and are generated by vital, ancient cellular structures called ribosomes.
Written By:
Carmen Leitch
NOV 18, 2019
Drug Discovery & Development
Sickle cell disease affects approximately 100,000 Americans. Currently, the only available cure for the disease is a cos
...
Written By:
Annie Lennon
NOV 06, 2019
Drug Discovery & Development
Scientists at Karolinska Institutet in Sweden were able to pinpoint 10 tumor-specific potential drug targets for the fat
...
Written By:
Nouran Amin
NOV 01, 2019
Chemistry & Physics
In a recent study, a group of biomedical researchers at Michigan State University developed a new platform for tweaking
...
Written By:
Daniel Duan
OCT 23, 2019
Immunology
Delivering gluten to the body in a friendly, harmless package may be the way for people with celiac disease to finally h
...
Written By:
Kara Marker
OCT 21, 2019
Technology
Researchers have developed a software system that converts cell phones into augmented reality (AR) portals that allows u
...
Written By:
Nouran Amin
OCT 15, 2019
Microbiology
We produce several liters of mucus every day to cover more than 200 square meters in the human body.
Written By:
Carmen Leitch
OCT 13, 2019
Microbiology
Now a team of scientists has found a molecule in human breast milk that may reduce the risk of illness and disease.
Written By:
Carmen Leitch
OCT 12, 2019
Immunology
The body’s own immune cells may be the common denominator in Alzheimer’s disease. In a new study of the rela
...
Written By:
Kara Marker
OCT 07, 2019
Clinical & Molecular DX
Hypertension is also known as high blood pressure is a serious condition. According to the Centers for Disease Cont
...
Written By:
Nupur Srivastava
SEP 29, 2019
Cell & Molecular Biology
Understanding how and when and why certain genes are or are not active is a critical aspect of biomedical research.
Written By:
Carmen Leitch
SEP 17, 2019
Cannabis Sciences
This is an introduction into cannabis genetics including chromosome number, genetic variation leading to expression diff
...
Written By:
Mauri Brueggeman
SEP 03, 2019
Microbiology
While attention has been brought to the issue and some progress has been made, hospital-acquired infections are still a
...
Written By:
Carmen Leitch
AUG 18, 2019
Cell & Molecular Biology
As tissues grow in a developing embryo, they have to fold in the right way to create the proper structures.
Written By:
Carmen Leitch
JUL 22, 2019
Plants & Animals
Getting a blood sample from a massive whale shark can be particularly challenging and would typically require administer
...
Written By:
Anthony Bouchard
JUL 11, 2019
Health & Medicine
The Pennsylvania Department of Health added anxiety disorders and Tourette's syndrome to a rather short list of heal
...
JUL 09, 2019
Genetics & Genomics
Agriculture has valued the production of a handful of staple foods, and genetic diversity among our crops has declined,
...
Written By:
Carmen Leitch
JUL 09, 2019
Drug Discovery & Development
Uveal melanoma is a rare and aggressive type of melanoma that targets the eye and affects an estimated 2,500 people in t
...
Written By:
Nouran Amin
JUN 18, 2019
Drug Discovery & Development
Researchers from the University of Sheffield in collaboration with Glasgow-based biotech company Mironid, have developed
...
Written By:
Nouran Amin
JUN 15, 2019
Cell & Molecular Biology
In RA, cells of the immune system mistakenly attack the joints, and cause the painful inflammation that is a hallmark of
...
Written By:
Carmen Leitch
JUN 07, 2019
Cell & Molecular Biology
Researchers were surprised to find that neurons aren't the only aged cells in the body.
Written By:
Carmen Leitch
JUN 07, 2019
Health & Medicine
A stem cell, by definition, must be able to self-replicate to make more stem cells and to differentiate into a matu
...
Written By:
Dena Aruta
MAY 24, 2019
Cancer
Castration-resistant prostate cancer (CRPC) is a particularly aggressive form of prostate cancer. Although the standard
...
Written By:
Kathryn DeMuth Sullivan