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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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FEB 23, 2020Immunology
Babies born more than three weeks before full term are met with complicated and often life-threatening health challenges ...Written By: Tara FernandesFEB 21, 2020Drug Discovery & Development
Studies on rats revealed that two existing drugs can boost repair machinery by triggering the release of bone marrow ste ...Written By: Nouran AminFEB 19, 2020Immunology
What do the gut microbiome, antibodies, and rainbow trout have in common? A lot, says researcher J. Oriol Sunyer from th ...Written By: Tara FernandesFEB 12, 2020Genetics & Genomics
The activity of genes can be altered with chemical tags that get added to the genome, so-called epigenetic modifications ...Written By: Carmen LeitchFEB 04, 2020Microbiology
The human metapneumovirus (HMPV) might now be well-known, but it is the second biggest cause of respiratory infections.Written By: Carmen LeitchFEB 04, 2020Cancer
Researchers from Osaka University have recently discovered a new function of the multifunctional enzyme entitled serine ...Written By: Kathryn DeMuth SullivanJAN 27, 2020Genetics & Genomics
Machine learning algorithms are increasingly being applied to the vast amount of genetic data that has been generated ov ...Written By: Carmen LeitchJAN 21, 2020Drug Discovery & Development
The FDA has recently approved Ayvakit (avapritinib) for the treatment of unresectable and metastatic gastrointestinal st ...Written By: Nouran AminJAN 21, 2020Cell & Molecular Biology
Drugs have to be rigorously tested before they can be offered to patients, so it can be much easier to find more than on ...Written By: Carmen LeitchJAN 20, 2020Cancer
A study from MIT. Harvard and the Dana-Farber Cancer Institute has concluded that almost 50 existing non-oncological dru ...Written By: Kathryn DeMuth SullivanJAN 07, 2020Immunology
T cells may be able to reach their full potential in the fight against cancer with a little nudge. In 2010, scientists f ...Written By: Kara MarkerDEC 31, 2019Genetics & Genomics
He Jiankui, the scientist behind the world’s first gene-edited babies in 2018, has been sentenced to three years i ...Written By: Annie LennonDEC 25, 2019Drug Discovery & Development
The US Food and Drug Administration has granted accelerated approval to new breast cancer drug, trastuzumab deruxtecan. ...Written By: Annie LennonDEC 18, 2019Genetics & Genomics
Cancer cells can adapt to mutations in the genome that might kill the cells by altering the activity of their genes.Written By: Carmen LeitchDEC 18, 2019Cancer
Pancreatic cancer is a dangerous disease for two reasons: its stealth and its resistance to many anti-cancer drugs. The ...Written By: Kathryn DeMuth SullivanDEC 17, 2019Microbiology
There may be a small silver lining to getting a cold or the flu.Written By: Carmen LeitchDEC 12, 2019Cell & Molecular Biology
While the human genome has been sequenced, there are plenty of parts of it that we don't know much about.Written By: Carmen LeitchDEC 11, 2019Drug Discovery & Development
Biomedical researchers at the University of California—Riverside, found that the therapeutic drug ‘tofacitin ...Written By: Nouran AminDEC 11, 2019Drug Discovery & Development
Researchers using mouse models of Alzheimer disease were able to demonstrate that the investigational drug candidates &l ...Written By: Nouran AminDEC 10, 2019Immunology
A specialized form of T cell emerges as a new focus for gastrointestinal health research, specifically in the context of ...Written By: Kara MarkerDEC 01, 2019Cell & Molecular Biology
Since the CRISPR gene editor was created, researchers around the world have tweaked and refined the tool to use it in a ...Written By: Carmen LeitchNOV 25, 2019Drug Discovery & Development
Researchers have long known that the cause behind Alexander disease is a genetic culprit—mainly a mutation leading ...Written By: Nouran AminNOV 24, 2019Cell & Molecular Biology
Proteins are critical to biology, and are generated by vital, ancient cellular structures called ribosomes.Written By: Carmen LeitchNOV 18, 2019Drug Discovery & Development
Sickle cell disease affects approximately 100,000 Americans. Currently, the only available cure for the disease is a cos ...Written By: Annie Lennon
FEB 23, 2020
Immunology
Babies born more than three weeks before full term are met with complicated and often life-threatening health challenges
...
Written By:
Tara Fernandes
FEB 21, 2020
Drug Discovery & Development
Studies on rats revealed that two existing drugs can boost repair machinery by triggering the release of bone marrow ste
...
Written By:
Nouran Amin
FEB 19, 2020
Immunology
What do the gut microbiome, antibodies, and rainbow trout have in common? A lot, says researcher J. Oriol Sunyer from th
...
Written By:
Tara Fernandes
FEB 12, 2020
Genetics & Genomics
The activity of genes can be altered with chemical tags that get added to the genome, so-called epigenetic modifications
...
Written By:
Carmen Leitch
FEB 04, 2020
Microbiology
The human metapneumovirus (HMPV) might now be well-known, but it is the second biggest cause of respiratory infections.
Written By:
Carmen Leitch
FEB 04, 2020
Cancer
Researchers from Osaka University have recently discovered a new function of the multifunctional enzyme entitled serine
...
Written By:
Kathryn DeMuth Sullivan
JAN 27, 2020
Genetics & Genomics
Machine learning algorithms are increasingly being applied to the vast amount of genetic data that has been generated ov
...
Written By:
Carmen Leitch
JAN 21, 2020
Drug Discovery & Development
The FDA has recently approved Ayvakit (avapritinib) for the treatment of unresectable and metastatic gastrointestinal st
...
Written By:
Nouran Amin
JAN 21, 2020
Cell & Molecular Biology
Drugs have to be rigorously tested before they can be offered to patients, so it can be much easier to find more than on
...
Written By:
Carmen Leitch
JAN 20, 2020
Cancer
A study from MIT. Harvard and the Dana-Farber Cancer Institute has concluded that almost 50 existing non-oncological dru
...
Written By:
Kathryn DeMuth Sullivan
JAN 07, 2020
Immunology
T cells may be able to reach their full potential in the fight against cancer with a little nudge. In 2010, scientists f
...
Written By:
Kara Marker
DEC 31, 2019
Genetics & Genomics
He Jiankui, the scientist behind the world’s first gene-edited babies in 2018, has been sentenced to three years i
...
Written By:
Annie Lennon
DEC 25, 2019
Drug Discovery & Development
The US Food and Drug Administration has granted accelerated approval to new breast cancer drug, trastuzumab deruxtecan.
...
Written By:
Annie Lennon
DEC 18, 2019
Genetics & Genomics
Cancer cells can adapt to mutations in the genome that might kill the cells by altering the activity of their genes.
Written By:
Carmen Leitch
DEC 18, 2019
Cancer
Pancreatic cancer is a dangerous disease for two reasons: its stealth and its resistance to many anti-cancer drugs. The
...
Written By:
Kathryn DeMuth Sullivan
DEC 17, 2019
Microbiology
There may be a small silver lining to getting a cold or the flu.
Written By:
Carmen Leitch
DEC 12, 2019
Cell & Molecular Biology
While the human genome has been sequenced, there are plenty of parts of it that we don't know much about.
Written By:
Carmen Leitch
DEC 11, 2019
Drug Discovery & Development
Biomedical researchers at the University of California—Riverside, found that the therapeutic drug ‘tofacitin
...
Written By:
Nouran Amin
DEC 11, 2019
Drug Discovery & Development
Researchers using mouse models of Alzheimer disease were able to demonstrate that the investigational drug candidates &l
...
Written By:
Nouran Amin
DEC 10, 2019
Immunology
A specialized form of T cell emerges as a new focus for gastrointestinal health research, specifically in the context of
...
Written By:
Kara Marker
DEC 01, 2019
Cell & Molecular Biology
Since the CRISPR gene editor was created, researchers around the world have tweaked and refined the tool to use it in a
...
Written By:
Carmen Leitch
NOV 25, 2019
Drug Discovery & Development
Researchers have long known that the cause behind Alexander disease is a genetic culprit—mainly a mutation leading
...
Written By:
Nouran Amin
NOV 24, 2019
Cell & Molecular Biology
Proteins are critical to biology, and are generated by vital, ancient cellular structures called ribosomes.
Written By:
Carmen Leitch
NOV 18, 2019
Drug Discovery & Development
Sickle cell disease affects approximately 100,000 Americans. Currently, the only available cure for the disease is a cos
...
Written By:
Annie Lennon