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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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AUG 11, 2018Cardiology
New targeted drug delivery system allows for rapid response to break down clots during heart attack, limiting cardiac da ...Written By: Caitlin WilliamsAUG 09, 2018Cell & Molecular Biology
A new method can track the formation and movement of lipids, DNA and proteins in live cells.Written By: Carmen LeitchAUG 08, 2018Immunology
Chemotherapy drug Doxorubicin disrupts metabolism that controls immune responses in the heart leading to heart toxicity.Written By: Caitlin WilliamsAUG 08, 2018Drug Discovery & Development
A brutal lung disease called Pulmonary Alveolar Proteinosis (PAP) is caused by a thick substance known as surfactant tha ...Written By: Nouran AminAUG 07, 2018Cancer
DNA methylation patterns in renal cell carcinoma (RCC) have a strong association with myelodysplastic syndrome DNA hyper ...Written By: Mauri BrueggemanAUG 06, 2018Cell & Molecular Biology
Researchers studying cocaine addiction have managed to significantly reduce relapse rates in a preclinical model.Written By: Carmen LeitchAUG 06, 2018Immunology
Maternal Dengue immunity produces CD8+ T cells that protect against fetal Zika infection preventing zika-related malform ...Written By: Caitlin WilliamsAUG 04, 2018Immunology
An infant's innate immune response develops from fetus to birth, but it may not be as "immature" as previously thought.Written By: Caitlin WilliamsAUG 03, 2018Genetics & Genomics
A new study challenges the prevailing view of how humans acquired an unusual trait - the spoken word.Written By: Carmen LeitchAUG 02, 2018Genetics & Genomics
In some of our body's tissues, cells have to replicate many times. That introduces a chance for new genetic errors every ...Written By: Carmen LeitchAUG 02, 2018Cannabis Sciences
The Ice Bucket Challenge brought attention to ALS (Amyotrophic Lateral Sclerosis) and the need for further research on t ...Written By: Amanda KahlAUG 01, 2018Videos
Every year, the Koch Institute at MIT shares some of the most stunning images produced at the research facility.Written By: Carmen LeitchAUG 01, 2018Cell & Molecular Biology
Depression can be hard to classify and therefore, challenging to treat. New work could help change that.Written By: Carmen LeitchAUG 01, 2018Drug Discovery & Development
According to a paper in the Proceedings of the National Academy of Sciences, a research team led by Dr. Vishal Gohil of ...Written By: Nouran AminJUL 31, 2018Cell & Molecular Biology
Cell use this shape when packing together to form structures.Written By: Carmen LeitchJUL 31, 2018Cancer
DNA replication is a carefully regulated process in each cell of the body. Researchers are looking at the mechanism of ...Written By: Mauri BrueggemanJUL 31, 2018Cardiology
Largest genome study of of its type identifies biological processes related to the heart's electrical activity.Written By: Caitlin WilliamsJUL 31, 2018Cancer
Researchers have determined that sodium thiosulfate's antioxidant properties can prevent hearing loss in pediatric cance ...Written By: Mauri BrueggemanJUL 30, 2018Cancer
Researchers have found key markers in identifying the progression of melanoma by stages.Written By: Mauri BrueggemanJUL 30, 2018Immunology
Childhood adversity alters the immune system which contributes to increased risk of addiction as an adult.Written By: Caitlin WilliamsJUL 28, 2018Cell & Molecular Biology
All the structures in the body arise from a fertilized cell, and scientists are learning more about how that happens.Written By: Carmen LeitchJUL 27, 2018Microbiology
Without the right experimental design, behavioral testing can easily produce the wrong results.Written By: Carmen LeitchJUL 26, 2018Health & Medicine
Since they first became widely available, studies on the safety of mobile phones have sought to determine if there are a ...Written By: Brenda Kelley KimJUL 25, 2018Cell & Molecular Biology
Alzheimer's disease is the sixth leading cause of death in the US.Written By: Carmen Leitch
AUG 11, 2018
Cardiology
New targeted drug delivery system allows for rapid response to break down clots during heart attack, limiting cardiac da
...
Written By:
Caitlin Williams
AUG 09, 2018
Cell & Molecular Biology
A new method can track the formation and movement of lipids, DNA and proteins in live cells.
Written By:
Carmen Leitch
AUG 08, 2018
Immunology
Chemotherapy drug Doxorubicin disrupts metabolism that controls immune responses in the heart leading to heart toxicity.
Written By:
Caitlin Williams
AUG 08, 2018
Drug Discovery & Development
A brutal lung disease called Pulmonary Alveolar Proteinosis (PAP) is caused by a thick substance known as surfactant tha
...
Written By:
Nouran Amin
AUG 07, 2018
Cancer
DNA methylation patterns in renal cell carcinoma (RCC) have a strong association with myelodysplastic syndrome DNA hyper
...
Written By:
Mauri Brueggeman
AUG 06, 2018
Cell & Molecular Biology
Researchers studying cocaine addiction have managed to significantly reduce relapse rates in a preclinical model.
Written By:
Carmen Leitch
AUG 06, 2018
Immunology
Maternal Dengue immunity produces CD8+ T cells that protect against fetal Zika infection preventing zika-related malform
...
Written By:
Caitlin Williams
AUG 04, 2018
Immunology
An infant's innate immune response develops from fetus to birth, but it may not be as "immature" as previously thought.
Written By:
Caitlin Williams
AUG 03, 2018
Genetics & Genomics
A new study challenges the prevailing view of how humans acquired an unusual trait - the spoken word.
Written By:
Carmen Leitch
AUG 02, 2018
Genetics & Genomics
In some of our body's tissues, cells have to replicate many times. That introduces a chance for new genetic errors every
...
Written By:
Carmen Leitch
AUG 02, 2018
Cannabis Sciences
The Ice Bucket Challenge brought attention to ALS (Amyotrophic Lateral Sclerosis) and the need for further research on t
...
Written By:
Amanda Kahl
AUG 01, 2018
Videos
Every year, the Koch Institute at MIT shares some of the most stunning images produced at the research facility.
Written By:
Carmen Leitch
AUG 01, 2018
Cell & Molecular Biology
Depression can be hard to classify and therefore, challenging to treat. New work could help change that.
Written By:
Carmen Leitch
AUG 01, 2018
Drug Discovery & Development
According to a paper in the Proceedings of the National Academy of Sciences, a research team led by Dr. Vishal Gohil of
...
Written By:
Nouran Amin
JUL 31, 2018
Cell & Molecular Biology
Cell use this shape when packing together to form structures.
Written By:
Carmen Leitch
JUL 31, 2018
Cancer
DNA replication is a carefully regulated process in each cell of the body. Researchers are looking at the mechanism of
...
Written By:
Mauri Brueggeman
JUL 31, 2018
Cardiology
Largest genome study of of its type identifies biological processes related to the heart's electrical activity.
Written By:
Caitlin Williams
JUL 31, 2018
Cancer
Researchers have determined that sodium thiosulfate's antioxidant properties can prevent hearing loss in pediatric cance
...
Written By:
Mauri Brueggeman
JUL 30, 2018
Cancer
Researchers have found key markers in identifying the progression of melanoma by stages.
Written By:
Mauri Brueggeman
JUL 30, 2018
Immunology
Childhood adversity alters the immune system which contributes to increased risk of addiction as an adult.
Written By:
Caitlin Williams
JUL 28, 2018
Cell & Molecular Biology
All the structures in the body arise from a fertilized cell, and scientists are learning more about how that happens.
Written By:
Carmen Leitch
JUL 27, 2018
Microbiology
Without the right experimental design, behavioral testing can easily produce the wrong results.
Written By:
Carmen Leitch
JUL 26, 2018
Health & Medicine
Since they first became widely available, studies on the safety of mobile phones have sought to determine if there are a
...
Written By:
Brenda Kelley Kim
JUL 25, 2018
Cell & Molecular Biology
Alzheimer's disease is the sixth leading cause of death in the US.
Written By:
Carmen Leitch