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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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JUL 25, 2018Immunology
Killer T cells of Ebola survivors respond better to nucleoproteins, not glycoproteins, potentially influencing Ebola vac ...Written By: Caitlin WilliamsJUL 24, 2018Drug Discovery & Development
Researchers at Lineberger Comprehensive Cancer Center in University of North Carolina revealed a therapeutic target for ...Written By: Nouran AminJUL 24, 2018Drug Discovery & Development
It would be a breakthrough for science if symptoms of aging were reversed in humans. Well, researchers at the University ...Written By: Nouran AminJUL 22, 2018Cell & Molecular Biology
Researchers are getting closer to creating targeted therapies that are delivered directly where needed.Written By: Carmen LeitchJUL 22, 2018Cardiology
Protein involved in blood vessel formation found to be higher in offspring of mothers who had gestational diabetes, hold ...Written By: Caitlin WilliamsJUL 21, 2018Immunology
Recent study shows that sensory cells native to the gut are found in Hassall's corpuscles in the thymus, these are shown ...Written By: Caitlin WilliamsJUL 20, 2018Genetics & Genomics
Although CRISPR has grabbed a lot of headlines in recent years, it is not the only gene-editing game in town.Written By: Carmen LeitchJUL 19, 2018Microbiology
For many years, scientists have been trying to learn more about the causes of autism.Written By: Carmen LeitchJUL 18, 2018Cannabis Sciences
Chemists have synthesized several variants of THC, the active ingredient in cannabis. The ability to alter its structure ...Written By: Futurity (futurity.org)JUL 17, 2018Cancer
A new subtype of small cell lung cancer is reported to account for potentially 20% of small cell lung cancers diagnosed; ...Written By: Mauri BrueggemanJUL 17, 2018Cancer
The largest coordinated study on Prostate cancer aims to look at both genetic and environmental factors that lead to inc ...Written By: Mauri BrueggemanJUL 17, 2018Drug Discovery & Development
International researchers have sought to be the first in mapping family trees of cancer cells in acute myeloid leukemia ...Written By: Nouran AminJUL 12, 2018Cell & Molecular Biology
New techniques that can make stem cells could have a big impact on therapeutics.Written By: Carmen LeitchJUL 12, 2018Infographics
Learn about the advantages and the technology behind 3D cellular image acquisition and analysis with this infographic fr ...JUL 11, 2018Microbiology
Scientists have learned how some pathogenic bacteria stick to cells in the intestine, which gets their infection started ...Written By: Carmen LeitchJUL 11, 2018Drug Discovery & Development
Acetazolamide, which is sold under the trade name Diamox and used to treat altitude sickness, is considere ...Written By: Nouran AminJUL 10, 2018Cancer
Researchers utilized genome-wide association studies to identify a variant SNP within a gene at 14q11.2 which is linked ...Written By: Mauri BrueggemanJUL 10, 2018Cancer
A new small molecule inhibitor, called PTC596, initiated apoptosis in MCL cells according to a study published this mont ...Written By: Mauri BrueggemanJUL 10, 2018Cell & Molecular Biology
Scientists discovered an enzyme that can harvest a versatile molecule from trash.Written By: Carmen LeitchJUL 09, 2018Immunology
The protein complex mTORC1 has been shown to integrate metabolic and signaling activity to determine the fate of T cell ...Written By: Caitlin WilliamsJUL 09, 2018Neuroscience
When researching diseases that affect the brain, it's difficult to ethically use human patients. There are experimen ...Written By: Brenda Kelley KimJUL 08, 2018Earth & The Environment
One of the principal arguments that solar energy comes up against is its obvious dependence on sunlight - and for places ...Written By: Kathryn DeMuth SullivanJUL 07, 2018Genetics & Genomics
Gender is a known factor in the development of neurological disorders. Now scientists think they know why.Written By: Carmen LeitchJUL 06, 2018Genetics & Genomics
After early setbacks, genetic therapeutics are being developed again.Written By: Carmen Leitch
JUL 25, 2018
Immunology
Killer T cells of Ebola survivors respond better to nucleoproteins, not glycoproteins, potentially influencing Ebola vac
...
Written By:
Caitlin Williams
JUL 24, 2018
Drug Discovery & Development
Researchers at Lineberger Comprehensive Cancer Center in University of North Carolina revealed a therapeutic target for
...
Written By:
Nouran Amin
JUL 24, 2018
Drug Discovery & Development
It would be a breakthrough for science if symptoms of aging were reversed in humans. Well, researchers at the University
...
Written By:
Nouran Amin
JUL 22, 2018
Cell & Molecular Biology
Researchers are getting closer to creating targeted therapies that are delivered directly where needed.
Written By:
Carmen Leitch
JUL 22, 2018
Cardiology
Protein involved in blood vessel formation found to be higher in offspring of mothers who had gestational diabetes, hold
...
Written By:
Caitlin Williams
JUL 21, 2018
Immunology
Recent study shows that sensory cells native to the gut are found in Hassall's corpuscles in the thymus, these are shown
...
Written By:
Caitlin Williams
JUL 20, 2018
Genetics & Genomics
Although CRISPR has grabbed a lot of headlines in recent years, it is not the only gene-editing game in town.
Written By:
Carmen Leitch
JUL 19, 2018
Microbiology
For many years, scientists have been trying to learn more about the causes of autism.
Written By:
Carmen Leitch
JUL 18, 2018
Cannabis Sciences
Chemists have synthesized several variants of THC, the active ingredient in cannabis. The ability to alter its structure
...
Written By:
Futurity (futurity.org)
JUL 17, 2018
Cancer
A new subtype of small cell lung cancer is reported to account for potentially 20% of small cell lung cancers diagnosed;
...
Written By:
Mauri Brueggeman
JUL 17, 2018
Cancer
The largest coordinated study on Prostate cancer aims to look at both genetic and environmental factors that lead to inc
...
Written By:
Mauri Brueggeman
JUL 17, 2018
Drug Discovery & Development
International researchers have sought to be the first in mapping family trees of cancer cells in acute myeloid leukemia
...
Written By:
Nouran Amin
JUL 12, 2018
Cell & Molecular Biology
New techniques that can make stem cells could have a big impact on therapeutics.
Written By:
Carmen Leitch
JUL 12, 2018
Infographics
Learn about the advantages and the technology behind 3D cellular image acquisition and analysis with this infographic fr
...
JUL 11, 2018
Microbiology
Scientists have learned how some pathogenic bacteria stick to cells in the intestine, which gets their infection started
...
Written By:
Carmen Leitch
JUL 11, 2018
Drug Discovery & Development
Acetazolamide, which is sold under the trade name Diamox and used to treat altitude sickness, is considere
...
Written By:
Nouran Amin
JUL 10, 2018
Cancer
Researchers utilized genome-wide association studies to identify a variant SNP within a gene at 14q11.2 which is linked
...
Written By:
Mauri Brueggeman
JUL 10, 2018
Cancer
A new small molecule inhibitor, called PTC596, initiated apoptosis in MCL cells according to a study published this mont
...
Written By:
Mauri Brueggeman
JUL 10, 2018
Cell & Molecular Biology
Scientists discovered an enzyme that can harvest a versatile molecule from trash.
Written By:
Carmen Leitch
JUL 09, 2018
Immunology
The protein complex mTORC1 has been shown to integrate metabolic and signaling activity to determine the fate of T cell
...
Written By:
Caitlin Williams
JUL 09, 2018
Neuroscience
When researching diseases that affect the brain, it's difficult to ethically use human patients. There are experimen
...
Written By:
Brenda Kelley Kim
JUL 08, 2018
Earth & The Environment
One of the principal arguments that solar energy comes up against is its obvious dependence on sunlight - and for places
...
Written By:
Kathryn DeMuth Sullivan
JUL 07, 2018
Genetics & Genomics
Gender is a known factor in the development of neurological disorders. Now scientists think they know why.
Written By:
Carmen Leitch
JUL 06, 2018
Genetics & Genomics
After early setbacks, genetic therapeutics are being developed again.
Written By:
Carmen Leitch