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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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SEP 25, 2015Cell & Molecular Biology
The mitochondria of the cell are unusual organelles that serve as tiny little power plants that provide energy to our ce ...Written By: Sarah HertrichSEP 25, 2015Genetics & Genomics
To protect people from infectious disease, clinicians can target pathogens and parasites with medicines such as antibiot ...Written By: Ilene SchneiderSEP 22, 2015Neuroscience
Stem cells can create tissue models that reflect human physiology. These stem cell-derived models can be used in researc ...Written By: Ilene SchneiderSEP 22, 2015Cancer
Researchers at the University of Adelaide in Australia have discovered the role played by a gene that suppresses th ...Written By: Ilene SchneiderSEP 22, 2015Genetics & Genomics
A modular system of proteins can detect a particular DNA sequence in a cell and then trigger a specific response, such a ...Written By: Ilene SchneiderSEP 21, 2015Cancer
Scientists at The Scripps Research Institute have discovered a critical role played by an enzyme in cancer and autoimmun ...Written By: Ilene SchneiderSEP 21, 2015Neuroscience
Is there a connection between the brain’s stress response and a protein related to Alzheimer’s disease? Rese ...Written By: Ilene SchneiderSEP 21, 2015Immunology
Last week allergy researchers from The Alfred and Monash University in Australia revealed a link between allergens in ce ...Written By: Kara MarkerSEP 19, 2015Neuroscience
The abnormal behavior of two genes (BDNF and DTNBP1) is related to the underlying cause of schizophrenia, providing a ne ...Written By: Ilene SchneiderSEP 19, 2015Neuroscience
While interactions between brain cells hold the key to healthy brain function and cognition, many of those interactions ...Written By: Ilene SchneiderSEP 18, 2015Cancer
Cells can adapt to overcome cancer drugs designed to interfere with their genetic controls, according to a study by Canc ...Written By: Ilene SchneiderSEP 16, 2015Cancer
University of Manchester scientists have identified a gene, FOXC1, that, if turned on, can cause more aggressive cancer ...Written By: Ilene SchneiderSEP 16, 2015Cancer
Pancreatic cancer stem cells (PancSCs) are virtually addicted to oxygen-based metabolism, and could be “suffocated ...Written By: Ilene SchneiderSEP 16, 2015Microbiology
Methicillin-Resistant Staphylococcus Aureus (MRSA) is a dangerous bacterium that has become increasingly resistant to mu ...Written By: Kara MarkerSEP 13, 2015Cancer
A team at the University of Pennsylvania reported that a multiple myeloma patient whose cancer had stopped respondi ...Written By: Ilene SchneiderSEP 11, 2015Cancer
The global market value for Non-Small Cell Lung Cancer (NSCLC) treatment will rise from $6.9 billion in 2014 to $10.9 bi ...Written By: Ilene SchneiderSEP 10, 2015Genetics & Genomics
An international team of scientists led by Sweden's Karolinska Institutet (http://ki.se/en/startpage?) has mapped fo ...Written By: Ilene SchneiderSEP 10, 2015Cancer
A drug-like molecule could prove valuable in cancer research with the potential of developing a new pharmaceutical. ...Written By: Ilene SchneiderSEP 10, 2015Immunology
Allergic reactions occur when the immune system overreacts to an environmental protein that's not threatening the bo ...Written By: Kara MarkerSEP 08, 2015Neuroscience
People who have type 2 diabetes could be at greater risk for the buildup of tangles of protein in their spinal fluid, ir ...Written By: Ilene SchneiderSEP 07, 2015Immunology
Our immune system is our protection against foreign invaders like harmful bacteria and viruses. When our immune cells re ...Written By: Kara MarkerSEP 06, 2015Cancer
Immunotherapy is powerful, and British researchers have found a way to make it even more so. By giving cancer patients a ...Written By: Ilene SchneiderSEP 06, 2015Neuroscience
What causes severe early infant epilepsy? Scientists at Karolinska Institutet and Karolinska University Hospital in Swed ...Written By: Ilene SchneiderSEP 06, 2015Neuroscience
Approximately 8 million Americans suffer from nightmares and flashbacks to a traumatic event. While this condition, post ...Written By: Ilene Schneider
SEP 25, 2015
Cell & Molecular Biology
The mitochondria of the cell are unusual organelles that serve as tiny little power plants that provide energy to our ce
...
Written By:
Sarah Hertrich
SEP 25, 2015
Genetics & Genomics
To protect people from infectious disease, clinicians can target pathogens and parasites with medicines such as antibiot
...
Written By:
Ilene Schneider
SEP 22, 2015
Neuroscience
Stem cells can create tissue models that reflect human physiology. These stem cell-derived models can be used in researc
...
Written By:
Ilene Schneider
SEP 22, 2015
Cancer
Researchers at the University of Adelaide in Australia have discovered the role played by a gene that suppresses th
...
Written By:
Ilene Schneider
SEP 22, 2015
Genetics & Genomics
A modular system of proteins can detect a particular DNA sequence in a cell and then trigger a specific response, such a
...
Written By:
Ilene Schneider
SEP 21, 2015
Cancer
Scientists at The Scripps Research Institute have discovered a critical role played by an enzyme in cancer and autoimmun
...
Written By:
Ilene Schneider
SEP 21, 2015
Neuroscience
Is there a connection between the brain’s stress response and a protein related to Alzheimer’s disease? Rese
...
Written By:
Ilene Schneider
SEP 21, 2015
Immunology
Last week allergy researchers from The Alfred and Monash University in Australia revealed a link between allergens in ce
...
Written By:
Kara Marker
SEP 19, 2015
Neuroscience
The abnormal behavior of two genes (BDNF and DTNBP1) is related to the underlying cause of schizophrenia, providing a ne
...
Written By:
Ilene Schneider
SEP 19, 2015
Neuroscience
While interactions between brain cells hold the key to healthy brain function and cognition, many of those interactions
...
Written By:
Ilene Schneider
SEP 18, 2015
Cancer
Cells can adapt to overcome cancer drugs designed to interfere with their genetic controls, according to a study by Canc
...
Written By:
Ilene Schneider
SEP 16, 2015
Cancer
University of Manchester scientists have identified a gene, FOXC1, that, if turned on, can cause more aggressive cancer
...
Written By:
Ilene Schneider
SEP 16, 2015
Cancer
Pancreatic cancer stem cells (PancSCs) are virtually addicted to oxygen-based metabolism, and could be “suffocated
...
Written By:
Ilene Schneider
SEP 16, 2015
Microbiology
Methicillin-Resistant Staphylococcus Aureus (MRSA) is a dangerous bacterium that has become increasingly resistant to mu
...
Written By:
Kara Marker
SEP 13, 2015
Cancer
A team at the University of Pennsylvania reported that a multiple myeloma patient whose cancer had stopped respondi
...
Written By:
Ilene Schneider
SEP 11, 2015
Cancer
The global market value for Non-Small Cell Lung Cancer (NSCLC) treatment will rise from $6.9 billion in 2014 to $10.9 bi
...
Written By:
Ilene Schneider
SEP 10, 2015
Genetics & Genomics
An international team of scientists led by Sweden's Karolinska Institutet (http://ki.se/en/startpage?) has mapped fo
...
Written By:
Ilene Schneider
SEP 10, 2015
Cancer
A drug-like molecule could prove valuable in cancer research with the potential of developing a new pharmaceutical.
...
Written By:
Ilene Schneider
SEP 10, 2015
Immunology
Allergic reactions occur when the immune system overreacts to an environmental protein that's not threatening the bo
...
Written By:
Kara Marker
SEP 08, 2015
Neuroscience
People who have type 2 diabetes could be at greater risk for the buildup of tangles of protein in their spinal fluid, ir
...
Written By:
Ilene Schneider
SEP 07, 2015
Immunology
Our immune system is our protection against foreign invaders like harmful bacteria and viruses. When our immune cells re
...
Written By:
Kara Marker
SEP 06, 2015
Cancer
Immunotherapy is powerful, and British researchers have found a way to make it even more so. By giving cancer patients a
...
Written By:
Ilene Schneider
SEP 06, 2015
Neuroscience
What causes severe early infant epilepsy? Scientists at Karolinska Institutet and Karolinska University Hospital in Swed
...
Written By:
Ilene Schneider
SEP 06, 2015
Neuroscience
Approximately 8 million Americans suffer from nightmares and flashbacks to a traumatic event. While this condition, post
...
Written By:
Ilene Schneider