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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • JUN 15, 2016 | 7:30 AM
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
      Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
      Speaker: Guinevere Kammeijer, MSc
      Sponsored By: Sciex, Sciex
      11 2
      JUN 14, 2016 | 8:00 AM
      More than data: A new generation of image sensors and signal processing
      More than data: A new generation of image sensors and signal processing
      DATE: June 14th, 2016 TIME: 8am Pacific time, 11am Eastern time Recent breakthroughs in image sensor performance and signal processing have joined to enable new possibilities for live cel...
      Speaker: Rachit Mohindra
      Sponsored By: Photometrics, Photometrics
      10
      JUN 02, 2016 | 8:00 AM
      WEBINAR: CE-SELEX:  Isolating High Affinity Aptamers Using Capillary Electrophoresis
      WEBINAR: CE-SELEX: Isolating High Affinity Aptamers Using Capillary...
           SELEX is a process that selects DNA or RNA from a random library of sequences based on their affinity for a target molecule.  These high affinity ligands, called apta...
      Speaker: Michael Bowser, PhD
      Sponsored By: Sciex, Sciex
      4 1
      MAY 26, 2016 | 8:00 AM
      Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA Seq
      Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA...
      DATE:  May 26, 2016TIME:  8am pacific time, 11am eastern timeJoin us live and learn about a breakthrough in TCR sequencing using single-cell analysis.T cells recognize spe...
      Speaker: Mike Stubbington, PhD , Tapio Lonnberg, PhD
      Sponsored By: Standard BioTools, Standard BioTools
      8
      MAY 24, 2016 | 8:00 AM
      Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
      Implement high-throughput 3D image analysis for samples from subcellular...
      DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
      Speaker: Oksana Sirenko, PhD , Steven Luke
      Sponsored By: Molecular Devices, Molecular Devices
      7 1
      MAY 12, 2016 | 1:30 PM
      Canon BioMedical - Revealing New Genotyping Solutions
      Canon BioMedical - Revealing New Genotyping Solutions
      Canon BioMedical was established last year to develop innovative technologies and solutions that empower biomedical research and healthcare communities. Our mission is broad and encompassing,...
      Speaker: Brian McNally, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      4
      MAY 12, 2016 | 12:00 PM
      Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
      Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
      The extravagant expectations around emerging technologies often gives way to a sense of disillusionment when the lofty expectations are not fulfilled. For genomics and precision precision to...
      Speaker: David Shaywitz, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 12, 2016 | 10:30 AM
      C.E. CREDITS
      Big data integration - Inferring and using individual patient network models
      Big data integration - Inferring and using individual patient...
      The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
      Speaker: Marieke Kuijjer, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      5
      MAY 11, 2016 | 1:30 PM
      C.E. CREDITS
      Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor Composition
      Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor...
      Human breast tumors have been shown to exhibit extensive inter- and intra-tumor heterogeneity. While recent advances in genomic technologies have allowed us to deconvolute this heterogeneity,...
      Speaker: Ioannis (Jiannis) Ragoussis, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      3
      MAY 11, 2016 | 10:30 AM
      Whole Genome? The Future of High-Quality Genomes & Transcriptomes
      Whole Genome? The Future of High-Quality Genomes & Transcriptomes
      New approaches to generate high-quality representations of human genomes and transcriptomes are now becoming available. In contrast to short-read “Whole-Genome” re-sequencing meth...
      Speaker: Jonas Korlach, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 10, 2016 | 8:00 AM
      The art of war, unleashing the immune system to fight cancer
      The art of war, unleashing the immune system to fight cancer
      DATE: May 10th, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Cancer is a complex, multifactorial disease that not only is a cause of major human suffering throughout history...
      Speaker: John Connolly, PhD
      Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
      18 2
      MAY 04, 2016 | 12:00 PM
      Development of a Mammalian Recombinant Protein Production Suite
      Development of a Mammalian Recombinant Protein Production Suite
      Complex recombinant protein biologics, such as monoclonal antibodies and coagulation factors, are key components of today’s biopharmaceutical industry. There are many effective paths fo...
      Speaker: Catherine Owczarek, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      MAY 04, 2016 | 10:00 AM
      The ExpiCHO transient expression system: Optimization of monoclonal antibody protein A purification
      The ExpiCHO transient expression system: Optimization of monoclonal...
      The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
      Speaker: Lina Mpanda, MSc.
      Presented at: 2016 Gibco ExpressionWorld
      2
      MAY 04, 2016 | 6:00 AM
      Streamlining the Drug Development Process with the ExpiCHO Transient Expression System
      Streamlining the Drug Development Process with the ExpiCHO Transient...
      CHO cells are the predominant host for biotherapeutic protein expression, with roughly 70% of licensed biologics manufactured in CHO.  Multiple attributes make CHO cells desirable for bi...
      Speaker: Jon Zmuda, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      APR 07, 2016 | 1:30 PM
      Introduction to exosomes and other extracellular vesicles the "the bodies molecular internet" for personalized & precision medicine.
      Introduction to exosomes and other extracellular vesicles the...
      A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based...
      Speaker: Rey Magana
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      2 1
      APR 07, 2016 | 9:00 AM
      The impact of precise medicine on the practice of classical pathology -- What are some of the challenges and opportunities?
      The impact of precise medicine on the practice of classical pathology...
      Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
      Speaker: Michael Donovan, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      2
      APR 06, 2016 | 1:30 PM
      Validation and Implementation of Whole-Exome Sequencing to Guide Precision Cancer Care
      Validation and Implementation of Whole-Exome Sequencing to Guide...
      Cancer remains the second leading cause of death in the United States.  Most tumors arise from a myriad of genetic changes that dysregulate cell growth and prompt survival.  Ident...
      Speaker: Hanna Rennert, PhD, F.A.C.M.G
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      4
      APR 06, 2016 | 1:30 PM
      The application of molecular diagnostics to stained cytology smears
      The application of molecular diagnostics to stained cytology smears
      Detection of mutational alterations is important for guiding treatment decisions of lung non-small cell carcinomas and thyroid nodules with atypical cytologic findings. Inoperable lung tumors...
      Speaker: Maja Oktay, MD, PhD , Sumanta Goswami, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      2
      MAR 29, 2016 | 8:00 AM
      WEBINAR: Applications of Targeted Gene Panels in Inherited Disease Research
      WEBINAR: Applications of Targeted Gene Panels in Inherited Disease...
      Recent advances in next-generation sequencing (NGS) have helped to accelerate the pace of discovery in the field of genetic disease research and testing. The ability to analyze multiple genes...
      Speaker: Brian Meyer, PhD , Robert Sebra, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent, Thermo Fisher Scientific - Ion Torrent
      11 3
      MAR 17, 2016 | 12:00 PM
      Keynote Speaker - Animal models in psychiatry research
      Keynote Speaker - Animal models in psychiatry research
      Schizophrenia, depression, bipolar disorder are all uniquely human conditions.  Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
      Speaker: Patricio O'Donnell, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      2
      MAR 17, 2016 | 7:30 AM
      Special Lecturer - NMDAR dysfunction in schizophrenia:  Implications for pathophysiology and basic neuroscience
      Special Lecturer - NMDAR dysfunction in schizophrenia: Implications...
      Schizophrenia (Sz) is a major mental disorder that affects ~1% of the population.  Although traditional models of Sz focused on dopaminergic dysfunction, newer models increasingly implic...
      Speaker: Daniel Javitt, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      2
      MAR 16, 2016 | 12:00 PM
      FTIR chemical imaging of CNS tissues for spatially resolved molecular chemical information
      FTIR chemical imaging of CNS tissues for spatially resolved molecular...
      This talk will provide an overview of Fourier Transform InfraRed (FTIR) chemical imaging as a powerful and versatile method for obtaining information about CNS tissues. By combining imaging a...
      Speaker: Kathleen Gough
      Presented at: Neuroscience Virtual Event Series 2016
      3
      MAR 16, 2016 | 10:30 AM
      Keynote Speaker - Regulation and Function of Neurogenesis in the Adult Hippocampus
      Keynote Speaker - Regulation and Function of Neurogenesis in the...
      In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
      Speaker: Fred Gage, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      4
      MAR 16, 2016 | 7:30 AM
      The Benefits of Combining Optogenetics, Microscopy and Electrophysiology
      The Benefits of Combining Optogenetics, Microscopy and Electrophysiology
      Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
      Speaker: Geraint Wilde, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      2
    JUN 15, 2016 | 7:30 AM
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
    Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
    Speaker: Guinevere Kammeijer, MSc
    Sponsored By: Sciex, Sciex
    11 2
    JUN 14, 2016 | 8:00 AM
    More than data: A new generation of image sensors and signal processing
    More than data: A new generation of image sensors and signal processing
    DATE: June 14th, 2016 TIME: 8am Pacific time, 11am Eastern time Recent breakthroughs in image sensor performance and signal processing have joined to enable new possibilities for live cel...
    Speaker: Rachit Mohindra
    Sponsored By: Photometrics, Photometrics
    10
    JUN 02, 2016 | 8:00 AM
    WEBINAR: CE-SELEX:  Isolating High Affinity Aptamers Using Capillary Electrophoresis
    WEBINAR: CE-SELEX: Isolating High Affinity Aptamers Using Capillary...
         SELEX is a process that selects DNA or RNA from a random library of sequences based on their affinity for a target molecule.  These high affinity ligands, called apta...
    Speaker: Michael Bowser, PhD
    Sponsored By: Sciex, Sciex
    4 1
    MAY 26, 2016 | 8:00 AM
    Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA Seq
    Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA...
    DATE:  May 26, 2016TIME:  8am pacific time, 11am eastern timeJoin us live and learn about a breakthrough in TCR sequencing using single-cell analysis.T cells recognize spe...
    Speaker: Mike Stubbington, PhD , Tapio Lonnberg, PhD
    Sponsored By: Standard BioTools, Standard BioTools
    8
    MAY 24, 2016 | 8:00 AM
    Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
    Implement high-throughput 3D image analysis for samples from subcellular...
    DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
    Speaker: Oksana Sirenko, PhD , Steven Luke
    Sponsored By: Molecular Devices, Molecular Devices
    7 1
     
     
  • MAY 12, 2016 | 1:30 PM
    Canon BioMedical - Revealing New Genotyping Solutions
    Canon BioMedical - Revealing New Genotyping Solutions
    Canon BioMedical was established last year to develop innovative technologies and solutions that empower biomedical research and healthcare communities. Our mission is broad and encompassing,...
    Speaker: Brian McNally, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    4
    MAY 12, 2016 | 12:00 PM
    Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
    Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
    The extravagant expectations around emerging technologies often gives way to a sense of disillusionment when the lofty expectations are not fulfilled. For genomics and precision precision to...
    Speaker: David Shaywitz, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 12, 2016 | 10:30 AM
    C.E. CREDITS
    Big data integration - Inferring and using individual patient network models
    Big data integration - Inferring and using individual patient...
    The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
    Speaker: Marieke Kuijjer, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    5
    MAY 11, 2016 | 1:30 PM
    C.E. CREDITS
    Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor Composition
    Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor...
    Human breast tumors have been shown to exhibit extensive inter- and intra-tumor heterogeneity. While recent advances in genomic technologies have allowed us to deconvolute this heterogeneity,...
    Speaker: Ioannis (Jiannis) Ragoussis, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    3
    MAY 11, 2016 | 10:30 AM
    Whole Genome? The Future of High-Quality Genomes & Transcriptomes
    Whole Genome? The Future of High-Quality Genomes & Transcriptomes
    New approaches to generate high-quality representations of human genomes and transcriptomes are now becoming available. In contrast to short-read “Whole-Genome” re-sequencing meth...
    Speaker: Jonas Korlach, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
     
     
  • MAY 10, 2016 | 8:00 AM
    The art of war, unleashing the immune system to fight cancer
    The art of war, unleashing the immune system to fight cancer
    DATE: May 10th, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Cancer is a complex, multifactorial disease that not only is a cause of major human suffering throughout history...
    Speaker: John Connolly, PhD
    Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
    18 2
    MAY 04, 2016 | 12:00 PM
    Development of a Mammalian Recombinant Protein Production Suite
    Development of a Mammalian Recombinant Protein Production Suite
    Complex recombinant protein biologics, such as monoclonal antibodies and coagulation factors, are key components of today’s biopharmaceutical industry. There are many effective paths fo...
    Speaker: Catherine Owczarek, PhD
    Presented at: 2016 Gibco ExpressionWorld
    2
    MAY 04, 2016 | 10:00 AM
    The ExpiCHO transient expression system: Optimization of monoclonal antibody protein A purification
    The ExpiCHO transient expression system: Optimization of monoclonal...
    The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
    Speaker: Lina Mpanda, MSc.
    Presented at: 2016 Gibco ExpressionWorld
    2
    MAY 04, 2016 | 6:00 AM
    Streamlining the Drug Development Process with the ExpiCHO Transient Expression System
    Streamlining the Drug Development Process with the ExpiCHO Transient...
    CHO cells are the predominant host for biotherapeutic protein expression, with roughly 70% of licensed biologics manufactured in CHO.  Multiple attributes make CHO cells desirable for bi...
    Speaker: Jon Zmuda, PhD
    Presented at: 2016 Gibco ExpressionWorld
    2
    APR 07, 2016 | 1:30 PM
    Introduction to exosomes and other extracellular vesicles the "the bodies molecular internet" for personalized & precision medicine.
    Introduction to exosomes and other extracellular vesicles the...
    A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based...
    Speaker: Rey Magana
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    2 1
     
     
  • APR 07, 2016 | 9:00 AM
    The impact of precise medicine on the practice of classical pathology -- What are some of the challenges and opportunities?
    The impact of precise medicine on the practice of classical pathology...
    Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
    Speaker: Michael Donovan, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    2
    APR 06, 2016 | 1:30 PM
    Validation and Implementation of Whole-Exome Sequencing to Guide Precision Cancer Care
    Validation and Implementation of Whole-Exome Sequencing to Guide...
    Cancer remains the second leading cause of death in the United States.  Most tumors arise from a myriad of genetic changes that dysregulate cell growth and prompt survival.  Ident...
    Speaker: Hanna Rennert, PhD, F.A.C.M.G
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    4
    APR 06, 2016 | 1:30 PM
    The application of molecular diagnostics to stained cytology smears
    The application of molecular diagnostics to stained cytology smears
    Detection of mutational alterations is important for guiding treatment decisions of lung non-small cell carcinomas and thyroid nodules with atypical cytologic findings. Inoperable lung tumors...
    Speaker: Maja Oktay, MD, PhD , Sumanta Goswami, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    2
    MAR 29, 2016 | 8:00 AM
    WEBINAR: Applications of Targeted Gene Panels in Inherited Disease Research
    WEBINAR: Applications of Targeted Gene Panels in Inherited Disease...
    Recent advances in next-generation sequencing (NGS) have helped to accelerate the pace of discovery in the field of genetic disease research and testing. The ability to analyze multiple genes...
    Speaker: Brian Meyer, PhD , Robert Sebra, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent, Thermo Fisher Scientific - Ion Torrent
    11 3
    MAR 17, 2016 | 12:00 PM
    Keynote Speaker - Animal models in psychiatry research
    Keynote Speaker - Animal models in psychiatry research
    Schizophrenia, depression, bipolar disorder are all uniquely human conditions.  Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
    Speaker: Patricio O'Donnell, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    2
     
     
  • MAR 17, 2016 | 7:30 AM
    Special Lecturer - NMDAR dysfunction in schizophrenia:  Implications for pathophysiology and basic neuroscience
    Special Lecturer - NMDAR dysfunction in schizophrenia: Implications...
    Schizophrenia (Sz) is a major mental disorder that affects ~1% of the population.  Although traditional models of Sz focused on dopaminergic dysfunction, newer models increasingly implic...
    Speaker: Daniel Javitt, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    2
    MAR 16, 2016 | 12:00 PM
    FTIR chemical imaging of CNS tissues for spatially resolved molecular chemical information
    FTIR chemical imaging of CNS tissues for spatially resolved molecular...
    This talk will provide an overview of Fourier Transform InfraRed (FTIR) chemical imaging as a powerful and versatile method for obtaining information about CNS tissues. By combining imaging a...
    Speaker: Kathleen Gough
    Presented at: Neuroscience Virtual Event Series 2016
    3
    MAR 16, 2016 | 10:30 AM
    Keynote Speaker - Regulation and Function of Neurogenesis in the Adult Hippocampus
    Keynote Speaker - Regulation and Function of Neurogenesis in the...
    In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
    Speaker: Fred Gage, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    4
    MAR 16, 2016 | 7:30 AM
    The Benefits of Combining Optogenetics, Microscopy and Electrophysiology
    The Benefits of Combining Optogenetics, Microscopy and Electrophysiology
    Optogenetics or optophysiology is a rapidly growing technique used across an ever broadening array of research fields. Investigators now genetically modify many signalling pathway elements to...
    Speaker: Geraint Wilde, PhD
    Presented at: Neuroscience Virtual Event Series 2016
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