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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • AUG 30, 2016 | 8:00 AM
      Human umbilical cord mesenchymal cells and the treatment of bronchopulmonary dysplasia
      Human umbilical cord mesenchymal cells and the treatment of bronchopulmonary...
      The human umbilical cord is a promising abundant source of mesenchymal stem cells (MSCs). Compare to other MSCs, the advantages of human umbilical cord MSCs (hUC-MSCs) are easily accessible a...
      Speaker: Willie Lin, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      AUG 24, 2016 | 8:00 AM
      Beyond Bone: Emerging Applications in Preclinical microCT Imaging
      Beyond Bone: Emerging Applications in Preclinical microCT Imaging
      DATE: August 24th 2016TIME:  8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
      Speaker: Gael Rochefort, PhD , Chris Damoci
      Sponsored By: Revvity
      32
      JUN 30, 2016 | 8:00 AM
      Surveying expression of immune checkpoint markers in the tissue microenvironment
      Surveying expression of immune checkpoint markers in the tissue...
      DATE:  June 30, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
      Speaker: Jeffrey Kim, PhD
      Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
      3 1
      JUN 30, 2016 | 7:30 AM
      Proteome centric precision medicine:  embracing pathological diversity
      Proteome centric precision medicine: embracing pathological diversity
      Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
      Speaker: Jennifer Van Eyk, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      8
      JUN 29, 2016 | 7:00 AM
      Raising antibody validation standards with knockout technology
      Raising antibody validation standards with knockout technology
      Antibodies are tremendously useful and versatile tools and they have found use in many areas of life science research. However, antibodies can be difficult to make and are used in inherently...
      Speaker: Alejandra Solache
      Presented at: Abcam virtual exhibition: support and products to advance your research
      Sponsored By: Abcam
      8
      JUN 28, 2016 | 8:00 AM
      Maximizing microscopy output in cell biology: A practical guide to high content imaging & analysis
      Maximizing microscopy output in cell biology: A practical guide...
      High content imaging and analysis offers a robust, high throughput method for analyzing large numbers of cells with the benefit of the spatial and temporal demarcation afforded by fluorescenc...
      Speaker: Nicholas Dolman, Ph.D.
      Presented at: Protein and Cell Analysis Education Series
      1
      JUN 28, 2016 | 6:00 AM
      Practical considerations for fluorescence microscopy
      Practical considerations for fluorescence microscopy
      In this presentation, we will go over some of the reasons you would want to consider using fluorescence imaging and give a brief introduction to using fluorescent probes for cell structure an...
      Speaker: Trillium Blackmer, Ph.D.
      Presented at: Protein and Cell Analysis Education Series
      4
      JUN 23, 2016 | 11:00 AM
      Spotlights on T cells: new developments for translational and basic T cell research
      Spotlights on T cells: new developments for translational and...
      DATE:  June 23, 2016 TIME:  11:00am Pacific time, 2:00pm Eastern time T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
      Speaker: Anne Richter, PhD
      Sponsored By: Miltenyi Biotec, Miltenyi Biotec
      6 1
      JUN 15, 2016 | 8:00 AM
      Novel  PET radiochemistries: Improving understanding and detection of disease
      Novel PET radiochemistries: Improving understanding and detection...
      DATE: June 15, 2016TIME:  08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
      Speaker: Timothy DeGrado, PhD , Roger Schibli, PhD
      Sponsored By: Revvity
      32 1
      JUN 15, 2016 | 7:30 AM
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
      Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
      Speaker: Guinevere Kammeijer, MSc
      Sponsored By: Sciex, Sciex
      11 2
      JUN 14, 2016 | 8:00 AM
      More than data: A new generation of image sensors and signal processing
      More than data: A new generation of image sensors and signal processing
      DATE: June 14th, 2016 TIME: 8am Pacific time, 11am Eastern time Recent breakthroughs in image sensor performance and signal processing have joined to enable new possibilities for live cel...
      Speaker: Rachit Mohindra
      Sponsored By: Photometrics, Photometrics
      10
      JUN 02, 2016 | 8:00 AM
      WEBINAR: CE-SELEX:  Isolating High Affinity Aptamers Using Capillary Electrophoresis
      WEBINAR: CE-SELEX: Isolating High Affinity Aptamers Using Capillary...
           SELEX is a process that selects DNA or RNA from a random library of sequences based on their affinity for a target molecule.  These high affinity ligands, called apta...
      Speaker: Michael Bowser, PhD
      Sponsored By: Sciex, Sciex
      4 1
      MAY 26, 2016 | 8:00 AM
      Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA Seq
      Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA...
      DATE:  May 26, 2016TIME:  8am pacific time, 11am eastern timeJoin us live and learn about a breakthrough in TCR sequencing using single-cell analysis.T cells recognize spe...
      Speaker: Mike Stubbington, PhD , Tapio Lonnberg, PhD
      Sponsored By: Standard BioTools, Standard BioTools
      8
      MAY 24, 2016 | 8:00 AM
      Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
      Implement high-throughput 3D image analysis for samples from subcellular...
      DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
      Speaker: Oksana Sirenko, PhD , Steven Luke
      Sponsored By: Molecular Devices, Molecular Devices
      7 1
      MAY 12, 2016 | 1:30 PM
      Canon BioMedical - Revealing New Genotyping Solutions
      Canon BioMedical - Revealing New Genotyping Solutions
      Canon BioMedical was established last year to develop innovative technologies and solutions that empower biomedical research and healthcare communities. Our mission is broad and encompassing,...
      Speaker: Brian McNally, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      4
      MAY 12, 2016 | 12:00 PM
      Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
      Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
      The extravagant expectations around emerging technologies often gives way to a sense of disillusionment when the lofty expectations are not fulfilled. For genomics and precision precision to...
      Speaker: David Shaywitz, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 12, 2016 | 10:30 AM
      C.E. CREDITS
      Big data integration - Inferring and using individual patient network models
      Big data integration - Inferring and using individual patient...
      The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
      Speaker: Marieke Kuijjer, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      5
      MAY 11, 2016 | 1:30 PM
      C.E. CREDITS
      Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor Composition
      Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor...
      Human breast tumors have been shown to exhibit extensive inter- and intra-tumor heterogeneity. While recent advances in genomic technologies have allowed us to deconvolute this heterogeneity,...
      Speaker: Ioannis (Jiannis) Ragoussis, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      3
      MAY 11, 2016 | 10:30 AM
      Whole Genome? The Future of High-Quality Genomes & Transcriptomes
      Whole Genome? The Future of High-Quality Genomes & Transcriptomes
      New approaches to generate high-quality representations of human genomes and transcriptomes are now becoming available. In contrast to short-read “Whole-Genome” re-sequencing meth...
      Speaker: Jonas Korlach, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 10, 2016 | 8:00 AM
      The art of war, unleashing the immune system to fight cancer
      The art of war, unleashing the immune system to fight cancer
      DATE: May 10th, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Cancer is a complex, multifactorial disease that not only is a cause of major human suffering throughout history...
      Speaker: John Connolly, PhD
      Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
      18 2
      MAY 04, 2016 | 12:00 PM
      Development of a Mammalian Recombinant Protein Production Suite
      Development of a Mammalian Recombinant Protein Production Suite
      Complex recombinant protein biologics, such as monoclonal antibodies and coagulation factors, are key components of today’s biopharmaceutical industry. There are many effective paths fo...
      Speaker: Catherine Owczarek, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      MAY 04, 2016 | 10:00 AM
      The ExpiCHO transient expression system: Optimization of monoclonal antibody protein A purification
      The ExpiCHO transient expression system: Optimization of monoclonal...
      The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
      Speaker: Lina Mpanda, MSc.
      Presented at: 2016 Gibco ExpressionWorld
      2
      MAY 04, 2016 | 6:00 AM
      Streamlining the Drug Development Process with the ExpiCHO Transient Expression System
      Streamlining the Drug Development Process with the ExpiCHO Transient...
      CHO cells are the predominant host for biotherapeutic protein expression, with roughly 70% of licensed biologics manufactured in CHO.  Multiple attributes make CHO cells desirable for bi...
      Speaker: Jon Zmuda, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      APR 07, 2016 | 1:30 PM
      Introduction to exosomes and other extracellular vesicles the "the bodies molecular internet" for personalized & precision medicine.
      Introduction to exosomes and other extracellular vesicles the...
      A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based...
      Speaker: Rey Magana
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      2 1
    AUG 30, 2016 | 8:00 AM
    Human umbilical cord mesenchymal cells and the treatment of bronchopulmonary dysplasia
    Human umbilical cord mesenchymal cells and the treatment of bronchopulmonary...
    The human umbilical cord is a promising abundant source of mesenchymal stem cells (MSCs). Compare to other MSCs, the advantages of human umbilical cord MSCs (hUC-MSCs) are easily accessible a...
    Speaker: Willie Lin, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    AUG 24, 2016 | 8:00 AM
    Beyond Bone: Emerging Applications in Preclinical microCT Imaging
    Beyond Bone: Emerging Applications in Preclinical microCT Imaging
    DATE: August 24th 2016TIME:  8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
    Speaker: Gael Rochefort, PhD , Chris Damoci
    Sponsored By: Revvity
    32
    JUN 30, 2016 | 8:00 AM
    Surveying expression of immune checkpoint markers in the tissue microenvironment
    Surveying expression of immune checkpoint markers in the tissue...
    DATE:  June 30, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
    Speaker: Jeffrey Kim, PhD
    Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
    3 1
    JUN 30, 2016 | 7:30 AM
    Proteome centric precision medicine:  embracing pathological diversity
    Proteome centric precision medicine: embracing pathological diversity
    Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
    Speaker: Jennifer Van Eyk, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    8
    JUN 29, 2016 | 7:00 AM
    Raising antibody validation standards with knockout technology
    Raising antibody validation standards with knockout technology
    Antibodies are tremendously useful and versatile tools and they have found use in many areas of life science research. However, antibodies can be difficult to make and are used in inherently...
    Speaker: Alejandra Solache
    Presented at: Abcam virtual exhibition: support and products to advance your research
    Sponsored By: Abcam
    8
     
     
  • JUN 28, 2016 | 8:00 AM
    Maximizing microscopy output in cell biology: A practical guide to high content imaging & analysis
    Maximizing microscopy output in cell biology: A practical guide...
    High content imaging and analysis offers a robust, high throughput method for analyzing large numbers of cells with the benefit of the spatial and temporal demarcation afforded by fluorescenc...
    Speaker: Nicholas Dolman, Ph.D.
    Presented at: Protein and Cell Analysis Education Series
    1
    JUN 28, 2016 | 6:00 AM
    Practical considerations for fluorescence microscopy
    Practical considerations for fluorescence microscopy
    In this presentation, we will go over some of the reasons you would want to consider using fluorescence imaging and give a brief introduction to using fluorescent probes for cell structure an...
    Speaker: Trillium Blackmer, Ph.D.
    Presented at: Protein and Cell Analysis Education Series
    4
    JUN 23, 2016 | 11:00 AM
    Spotlights on T cells: new developments for translational and basic T cell research
    Spotlights on T cells: new developments for translational and...
    DATE:  June 23, 2016 TIME:  11:00am Pacific time, 2:00pm Eastern time T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
    Speaker: Anne Richter, PhD
    Sponsored By: Miltenyi Biotec, Miltenyi Biotec
    6 1
    JUN 15, 2016 | 8:00 AM
    Novel  PET radiochemistries: Improving understanding and detection of disease
    Novel PET radiochemistries: Improving understanding and detection...
    DATE: June 15, 2016TIME:  08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
    Speaker: Timothy DeGrado, PhD , Roger Schibli, PhD
    Sponsored By: Revvity
    32 1
    JUN 15, 2016 | 7:30 AM
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
    Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
    Speaker: Guinevere Kammeijer, MSc
    Sponsored By: Sciex, Sciex
    11 2
     
     
  • JUN 14, 2016 | 8:00 AM
    More than data: A new generation of image sensors and signal processing
    More than data: A new generation of image sensors and signal processing
    DATE: June 14th, 2016 TIME: 8am Pacific time, 11am Eastern time Recent breakthroughs in image sensor performance and signal processing have joined to enable new possibilities for live cel...
    Speaker: Rachit Mohindra
    Sponsored By: Photometrics, Photometrics
    10
    JUN 02, 2016 | 8:00 AM
    WEBINAR: CE-SELEX:  Isolating High Affinity Aptamers Using Capillary Electrophoresis
    WEBINAR: CE-SELEX: Isolating High Affinity Aptamers Using Capillary...
         SELEX is a process that selects DNA or RNA from a random library of sequences based on their affinity for a target molecule.  These high affinity ligands, called apta...
    Speaker: Michael Bowser, PhD
    Sponsored By: Sciex, Sciex
    4 1
    MAY 26, 2016 | 8:00 AM
    Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA Seq
    Linking T Cell Clonotype to Phenotype with TCR Single-Cell RNA...
    DATE:  May 26, 2016TIME:  8am pacific time, 11am eastern timeJoin us live and learn about a breakthrough in TCR sequencing using single-cell analysis.T cells recognize spe...
    Speaker: Mike Stubbington, PhD , Tapio Lonnberg, PhD
    Sponsored By: Standard BioTools, Standard BioTools
    8
    MAY 24, 2016 | 8:00 AM
    Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
    Implement high-throughput 3D image analysis for samples from subcellular...
    DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
    Speaker: Oksana Sirenko, PhD , Steven Luke
    Sponsored By: Molecular Devices, Molecular Devices
    7 1
    MAY 12, 2016 | 1:30 PM
    Canon BioMedical - Revealing New Genotyping Solutions
    Canon BioMedical - Revealing New Genotyping Solutions
    Canon BioMedical was established last year to develop innovative technologies and solutions that empower biomedical research and healthcare communities. Our mission is broad and encompassing,...
    Speaker: Brian McNally, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    4
     
     
  • MAY 12, 2016 | 12:00 PM
    Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
    Precision Medicine 2.0: Impact Requires Data, Collaboration, Champions
    The extravagant expectations around emerging technologies often gives way to a sense of disillusionment when the lofty expectations are not fulfilled. For genomics and precision precision to...
    Speaker: David Shaywitz, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 12, 2016 | 10:30 AM
    C.E. CREDITS
    Big data integration - Inferring and using individual patient network models
    Big data integration - Inferring and using individual patient...
    The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
    Speaker: Marieke Kuijjer, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    5
    MAY 11, 2016 | 1:30 PM
    C.E. CREDITS
    Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor Composition
    Microfluidic Single Cell Exome-seq and RNA-seq analysis of Tumor...
    Human breast tumors have been shown to exhibit extensive inter- and intra-tumor heterogeneity. While recent advances in genomic technologies have allowed us to deconvolute this heterogeneity,...
    Speaker: Ioannis (Jiannis) Ragoussis, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    3
    MAY 11, 2016 | 10:30 AM
    Whole Genome? The Future of High-Quality Genomes & Transcriptomes
    Whole Genome? The Future of High-Quality Genomes & Transcriptomes
    New approaches to generate high-quality representations of human genomes and transcriptomes are now becoming available. In contrast to short-read “Whole-Genome” re-sequencing meth...
    Speaker: Jonas Korlach, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 10, 2016 | 8:00 AM
    The art of war, unleashing the immune system to fight cancer
    The art of war, unleashing the immune system to fight cancer
    DATE: May 10th, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Cancer is a complex, multifactorial disease that not only is a cause of major human suffering throughout history...
    Speaker: John Connolly, PhD
    Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
    18 2
     
     
  • MAY 04, 2016 | 12:00 PM
    Development of a Mammalian Recombinant Protein Production Suite
    Development of a Mammalian Recombinant Protein Production Suite
    Complex recombinant protein biologics, such as monoclonal antibodies and coagulation factors, are key components of today’s biopharmaceutical industry. There are many effective paths fo...
    Speaker: Catherine Owczarek, PhD
    Presented at: 2016 Gibco ExpressionWorld
    2
    MAY 04, 2016 | 10:00 AM
    The ExpiCHO transient expression system: Optimization of monoclonal antibody protein A purification
    The ExpiCHO transient expression system: Optimization of monoclonal...
    The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
    Speaker: Lina Mpanda, MSc.
    Presented at: 2016 Gibco ExpressionWorld
    2
    MAY 04, 2016 | 6:00 AM
    Streamlining the Drug Development Process with the ExpiCHO Transient Expression System
    Streamlining the Drug Development Process with the ExpiCHO Transient...
    CHO cells are the predominant host for biotherapeutic protein expression, with roughly 70% of licensed biologics manufactured in CHO.  Multiple attributes make CHO cells desirable for bi...
    Speaker: Jon Zmuda, PhD
    Presented at: 2016 Gibco ExpressionWorld
    2
    APR 07, 2016 | 1:30 PM
    Introduction to exosomes and other extracellular vesicles the "the bodies molecular internet" for personalized & precision medicine.
    Introduction to exosomes and other extracellular vesicles the...
    A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based...
    Speaker: Rey Magana
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    2 1
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