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    CHO Cells

    Chinese hamster ovary (CHO) cells are an epithelial cell line derived from the ovary of the Chinese hamster, often used in biological and medical research and commercially in the production of therapeutic proteins. They have found wide use in studies of genetics, toxicity screening, nutrition and gene expression, particularly to express recombinant proteins. CHO cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics.

    Webinars

    • On Demand
      Diosgenin Induces Anti-Hyperalgesic Effect via Antagonism of Transient Receptor Potential Vanilloid 1 in Pain Model
      Diosgenin Induces Anti-Hyperalgesic Effect via Antagonism of Transient...
      Diosgenin is a botanical steroidal saponin with anti-inflammatory, antioxidant, anti-thrombotic, anti- apoptotic, anti-depressant, and anti-nociceptive properties. However, it's unknown...
      Speaker: Dr. Md. Mahbubur Rahman, DVM, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2024
      2
      OCT 24, 2023 | 9:00 PM
      Protein Expression Webinar
      Protein Expression Webinar
      This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
      Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      FEB 15, 2023 | 7:00 AM
      Scattering Microscopy: Label-Free Imaging Approaches
      Scattering Microscopy: Label-Free Imaging Approaches
      Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
      Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
      Sponsored By: Teledyne Photometrics
      28
      SEP 21, 2022 | 9:00 AM
      Arctis Cryo-Plasma-FIB for throughput and connectivity in cellular cryo-electron tomography
      Arctis Cryo-Plasma-FIB for throughput and connectivity in cellular...
      Date: September 21, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Cellular cryo-electron tomography is a high-resolution technique that enables imaging of the molecular machinery of...
      Speaker: Alex Rigort , Michael Grange
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific - Electron Microscopy
      15
      AUG 16, 2022 | 9:00 AM
      A novel and rapid platform to generate gram-level antibodies for diagnostic and therapeutic use
      A novel and rapid platform to generate gram-level antibodies for...
      Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
      Speaker: Hao Tan, PhD
      Sponsored By: GenScript
      12
      OCT 27, 2021 | 6:00 AM
      Comprehensive characterization of Etanercept using the ZenoTOF 7600 system
      Comprehensive characterization of Etanercept using the ZenoTOF...
      Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
      Speaker: Xuezhi Bi, PhD
      Sponsored By: SCIEX
      5
      JUL 13, 2021 | 11:00 AM
      Monoclonality Assurance Using CloneSelect Single-Cell Printer and CloneSelect Imager in Human Stem Cell (hSC) Engineering Workflow
      Monoclonality Assurance Using CloneSelect Single-Cell Printer...
      Date: July 13, 2021 Time: 11:00am (PDT), 1:00pm (EDT) 1 R&D, Cell Culture & Fermentation Sciences, Bio Pharmaceutical Development, AstraZeneca, Gaithersburg, USA, 2 R&D, ADPE, Ce...
      Speaker: Gargi Roy
      Sponsored By: Molecular Devices
      9 10
      MAY 25, 2021 | 8:00 AM
      Complete Workflow Solution from Gene-to-Protein
      Complete Workflow Solution from Gene-to-Protein
      Date: May 25, 2021 Time: 8:00am (PDT) Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, bu...
      Speaker: Stephan Fath, PhD
      Sponsored By: Thermo Fisher Scientific
      16 1
      APR 07, 2021 | 9:00 AM
      Keynote Presentation: Doing more with less - Maximizing Phase Appropriate DOE Strategies
      Keynote Presentation: Doing more with less - Maximizing Phase...
      One challenge pharmaceutical companies face, is moving promising biotherapeutic products into the clinic as fast as safely possible. Devoting the correct amount of time and resources to earl...
      Speaker: Patricia McNeill
      Presented at: Bioprocessing Virtual Event Series 2021
      Sponsored By: Roche Diagnostics
      1
      APR 07, 2021 | 12:00 AM
      A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells
      A Chinese hamster transcription start site atlas that enables...
      Chinese hamster ovary (CHO) cells are the most widely used cells for producing biopharmaceuticals. Engineering gene expression in CHO is key to improving drug quality and affordability. Howe...
      Speaker: Isaac Shamie
      Presented at: Bioprocessing Virtual Event Series 2021
      1
      SEP 23, 2020 | 10:30 AM
      iPSC- and patient- derived intestinal organoids for gastrointestinal research
      iPSC- and patient- derived intestinal organoids for gastrointestinal...
      Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
      Speaker: Kevin Su
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      JUL 22, 2020 | 10:00 AM
      Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
      Molecular Diagnostic Solutions in a Pandemic: Planning for the...
      DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
      Speaker: Heba Mostafa, MD, PhD, D(ABMM)
      Sponsored By: GenMark Dx
      27 13
      JUN 02, 2020 | 7:00 AM
      Harnessing the Power of Protein Expression Systems in Vaccine Development
      Harnessing the Power of Protein Expression Systems in Vaccine...
      DATE: June 2, 2020 TIME: 7:00am PT, 10:00am ET In just a few months COVID-19 has risen from a regional crisis to a global threat, and drug makers are now scrambling to develop vaccines aimed...
      Speaker: Roland Leathers, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      15 1
      APR 15, 2020 | 4:00 PM
      From cell seeding to analysis - Getting the best out of your cell-based assay
      From cell seeding to analysis - Getting the best out of your cell-based...
      DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
      Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
      Sponsored By: Eppendorf, Promega
      19 2
      MAR 26, 2020 | 9:00 AM
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
      DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
      Speaker: Namritha Ravinder
      Sponsored By: Thermo Fisher Scientific
      7
      NOV 07, 2019 | 9:00 AM
      Factor V Expression in ExpiCHO Cells
      Factor V Expression in ExpiCHO Cells
      DATE: November 7, 2019 TIME: 9:00am PST, 12:00pm EST In collaboration with Hematherix and Thermo Fisher, Dr. Laurent Mosnier is investigating a new treatment for acute traumatic bl...
      Speaker: Laurent Mosnier, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      5 2
      OCT 22, 2019 | 9:00 AM
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
      DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
      Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
      Sponsored By: Advanced Instruments
      10 1
      SEP 25, 2019 | 8:00 AM
      Expression, Purification and Characterization of Difficult to Express Membrane Proteins in the Expi293 and ExpiCHO Expression Systems:  Case study of Potassium chloride co-transporter KCC2
      Expression, Purification and Characterization of Difficult to...
      DATE: September 25, 2019TIME: 8:00am PT, 11:00am ET This talk will focus on strategies for optimizing expression levels of membrane proteins using the Gibcoâ„¢ Expi293â„¢ and ExpiCHOâ„¢ Expres...
      Speaker: Anass Jawhari, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      4
      SEP 10, 2019 | 3:00 PM
      From cell seeding to analysis - Getting the best out of your cell-based assay
      From cell seeding to analysis - Getting the best out of your cell-based...
      DATE: September 10, 2019 TIME: 3:00pm CEST, 06:00am PT, 09:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be...
      Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
      Sponsored By: Eppendorf, Promega
      16
      AUG 29, 2019 | 9:00 AM
      Enabling Next-Generation Targeted siRNA Therapies with ExpiCHO
      Enabling Next-Generation Targeted siRNA Therapies with ExpiCHO
      DATE: August 29, 2019TIME: 9:00am PT/ 12:00pm ET Monoclonal antibodies (mAbs) are a cornerstone of modern biomedical research and biotherapeutics. Therefore, reproducibly obtai...
      Speaker: Ian Huggins, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUN 19, 2019 | 10:00 AM
      Getting started in 3D:  Ask an Expert
      Getting started in 3D: Ask an Expert
      DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
      Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
      Sponsored By: Thermo Fisher Scientific
      6
      MAY 23, 2019 | 9:00 AM
      Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
      Doing More with Less: Stem Cells Regulate Their Fate by Altering...
      DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
      Speaker: Melika Sarem, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      APR 17, 2019 | 9:00 AM
      You've cultured an organoid and spheroid... now what?
      You've cultured an organoid and spheroid... now what?
      DATE:  April 17, 2019TIME:  9:00am PDT...
      Speaker: Takanori Takebe
      Sponsored By: Thermo Fisher Scientific
      5
      APR 03, 2019 | 9:00 AM
      How to analyze/characterize your 3D culture
      How to analyze/characterize your 3D culture
      DATE:  April 3, 2019TIME:  9:00am PDT...
      Speaker: Chris Langsdorf
      Sponsored By: Thermo Fisher Scientific
      6
    On Demand
    Diosgenin Induces Anti-Hyperalgesic Effect via Antagonism of Transient Receptor Potential Vanilloid 1 in Pain Model
    Diosgenin Induces Anti-Hyperalgesic Effect via Antagonism of Transient...
    Diosgenin is a botanical steroidal saponin with anti-inflammatory, antioxidant, anti-thrombotic, anti- apoptotic, anti-depressant, and anti-nociceptive properties. However, it's unknown...
    Speaker: Dr. Md. Mahbubur Rahman, DVM, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2024
    2
    OCT 24, 2023 | 9:00 PM
    Protein Expression Webinar
    Protein Expression Webinar
    This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
    Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
    Sponsored By: Thermo Fisher Scientific
    15
    FEB 15, 2023 | 7:00 AM
    Scattering Microscopy: Label-Free Imaging Approaches
    Scattering Microscopy: Label-Free Imaging Approaches
    Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
    Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
    Sponsored By: Teledyne Photometrics
    28
    SEP 21, 2022 | 9:00 AM
    Arctis Cryo-Plasma-FIB for throughput and connectivity in cellular cryo-electron tomography
    Arctis Cryo-Plasma-FIB for throughput and connectivity in cellular...
    Date: September 21, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Cellular cryo-electron tomography is a high-resolution technique that enables imaging of the molecular machinery of...
    Speaker: Alex Rigort , Michael Grange
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific - Electron Microscopy
    15
    AUG 16, 2022 | 9:00 AM
    A novel and rapid platform to generate gram-level antibodies for diagnostic and therapeutic use
    A novel and rapid platform to generate gram-level antibodies for...
    Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
    Speaker: Hao Tan, PhD
    Sponsored By: GenScript
    12
     
     
  • OCT 27, 2021 | 6:00 AM
    Comprehensive characterization of Etanercept using the ZenoTOF 7600 system
    Comprehensive characterization of Etanercept using the ZenoTOF...
    Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
    Speaker: Xuezhi Bi, PhD
    Sponsored By: SCIEX
    5
    JUL 13, 2021 | 11:00 AM
    Monoclonality Assurance Using CloneSelect Single-Cell Printer and CloneSelect Imager in Human Stem Cell (hSC) Engineering Workflow
    Monoclonality Assurance Using CloneSelect Single-Cell Printer...
    Date: July 13, 2021 Time: 11:00am (PDT), 1:00pm (EDT) 1 R&D, Cell Culture & Fermentation Sciences, Bio Pharmaceutical Development, AstraZeneca, Gaithersburg, USA, 2 R&D, ADPE, Ce...
    Speaker: Gargi Roy
    Sponsored By: Molecular Devices
    9 10
    MAY 25, 2021 | 8:00 AM
    Complete Workflow Solution from Gene-to-Protein
    Complete Workflow Solution from Gene-to-Protein
    Date: May 25, 2021 Time: 8:00am (PDT) Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, bu...
    Speaker: Stephan Fath, PhD
    Sponsored By: Thermo Fisher Scientific
    16 1
    APR 07, 2021 | 9:00 AM
    Keynote Presentation: Doing more with less - Maximizing Phase Appropriate DOE Strategies
    Keynote Presentation: Doing more with less - Maximizing Phase...
    One challenge pharmaceutical companies face, is moving promising biotherapeutic products into the clinic as fast as safely possible. Devoting the correct amount of time and resources to earl...
    Speaker: Patricia McNeill
    Presented at: Bioprocessing Virtual Event Series 2021
    Sponsored By: Roche Diagnostics
    1
    APR 07, 2021 | 12:00 AM
    A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells
    A Chinese hamster transcription start site atlas that enables...
    Chinese hamster ovary (CHO) cells are the most widely used cells for producing biopharmaceuticals. Engineering gene expression in CHO is key to improving drug quality and affordability. Howe...
    Speaker: Isaac Shamie
    Presented at: Bioprocessing Virtual Event Series 2021
    1
     
     
  • SEP 23, 2020 | 10:30 AM
    iPSC- and patient- derived intestinal organoids for gastrointestinal research
    iPSC- and patient- derived intestinal organoids for gastrointestinal...
    Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
    Speaker: Kevin Su
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    JUL 22, 2020 | 10:00 AM
    Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
    Molecular Diagnostic Solutions in a Pandemic: Planning for the...
    DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
    Speaker: Heba Mostafa, MD, PhD, D(ABMM)
    Sponsored By: GenMark Dx
    27 13
    JUN 02, 2020 | 7:00 AM
    Harnessing the Power of Protein Expression Systems in Vaccine Development
    Harnessing the Power of Protein Expression Systems in Vaccine...
    DATE: June 2, 2020 TIME: 7:00am PT, 10:00am ET In just a few months COVID-19 has risen from a regional crisis to a global threat, and drug makers are now scrambling to develop vaccines aimed...
    Speaker: Roland Leathers, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    15 1
    APR 15, 2020 | 4:00 PM
    From cell seeding to analysis - Getting the best out of your cell-based assay
    From cell seeding to analysis - Getting the best out of your cell-based...
    DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
    Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
    Sponsored By: Eppendorf, Promega
    19 2
    MAR 26, 2020 | 9:00 AM
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
    DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
    Speaker: Namritha Ravinder
    Sponsored By: Thermo Fisher Scientific
    7
     
     
  • NOV 07, 2019 | 9:00 AM
    Factor V Expression in ExpiCHO Cells
    Factor V Expression in ExpiCHO Cells
    DATE: November 7, 2019 TIME: 9:00am PST, 12:00pm EST In collaboration with Hematherix and Thermo Fisher, Dr. Laurent Mosnier is investigating a new treatment for acute traumatic bl...
    Speaker: Laurent Mosnier, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    5 2
    OCT 22, 2019 | 9:00 AM
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
    DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
    Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
    Sponsored By: Advanced Instruments
    10 1
    SEP 25, 2019 | 8:00 AM
    Expression, Purification and Characterization of Difficult to Express Membrane Proteins in the Expi293 and ExpiCHO Expression Systems:  Case study of Potassium chloride co-transporter KCC2
    Expression, Purification and Characterization of Difficult to...
    DATE: September 25, 2019TIME: 8:00am PT, 11:00am ET This talk will focus on strategies for optimizing expression levels of membrane proteins using the Gibcoâ„¢ Expi293â„¢ and ExpiCHOâ„¢ Expres...
    Speaker: Anass Jawhari, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    4
    SEP 10, 2019 | 3:00 PM
    From cell seeding to analysis - Getting the best out of your cell-based assay
    From cell seeding to analysis - Getting the best out of your cell-based...
    DATE: September 10, 2019 TIME: 3:00pm CEST, 06:00am PT, 09:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be...
    Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
    Sponsored By: Eppendorf, Promega
    16
    AUG 29, 2019 | 9:00 AM
    Enabling Next-Generation Targeted siRNA Therapies with ExpiCHO
    Enabling Next-Generation Targeted siRNA Therapies with ExpiCHO
    DATE: August 29, 2019TIME: 9:00am PT/ 12:00pm ET Monoclonal antibodies (mAbs) are a cornerstone of modern biomedical research and biotherapeutics. Therefore, reproducibly obtai...
    Speaker: Ian Huggins, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
     
     
  • JUN 19, 2019 | 10:00 AM
    Getting started in 3D:  Ask an Expert
    Getting started in 3D: Ask an Expert
    DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
    Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
    Sponsored By: Thermo Fisher Scientific
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    MAY 23, 2019 | 9:00 AM
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    DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
    Speaker: Melika Sarem, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    APR 17, 2019 | 9:00 AM
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    DATE:  April 17, 2019TIME:  9:00am PDT...
    Speaker: Takanori Takebe
    Sponsored By: Thermo Fisher Scientific
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    APR 03, 2019 | 9:00 AM
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    How to analyze/characterize your 3D culture
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    Speaker: Chris Langsdorf
    Sponsored By: Thermo Fisher Scientific
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