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Compound screening
Compound screening in an important step in the drug discovery pipeline. Performed in a laboratory setting, compound screening identifies compounds in small molecules that have a beneficial biological impact. Once identified, compounds are held in libraries containing information and details in a searchable formal.
AUG 27, 2020 | 7:00 AM
DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
JUN 30, 2020 | 9:00 AM
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
MAY 12, 2020 | 9:00 AM
NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
MAY 06, 2020 | 12:00 AM
Hydroxychloroquine and chloroquine are long-standing antimalarial drugs recently brought into the spotlight as potential treatments for the pandemic-causing coronavirus (SARS-CoV-2). Notable...
MAR 25, 2020 | 6:00 AM
Household produce varieties such as ‘Red Delicious,’ ‘Campari,’ and ‘Earlidew’ have been selectively bred and have been enhanced for flavor since the 1990...
JAN 14, 2020 | 8:00 AM
DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
OCT 24, 2019 | 10:30 AM
Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
SEP 27, 2019 | 9:00 AM
DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
SEP 24, 2019 | 8:00 AM
DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
AUG 22, 2019 | 6:00 AM
Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
FEB 27, 2019 | 3:00 PM
In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
NOV 06, 2018 | 12:00 AM
The last decade has seen a significant shift in the way that mammalian cells are used in biomedical science. Researchers are increasingly turning from simple, reductionist recombinant cells t...
NOV 05, 2018 | 12:00 AM
Biomedical researchers are increasingly using advanced human cell models for translational biology and therapeutic discovery studies. These include patient-specific samples, cultured micro-ti...
NOV 01, 2018 | 12:00 AM
Deriving deeper biological insight & improving productivity in immune-cell biologyThe most common in vitro methods for immunologists to analyze cells of the immune system are flow cyt...
NOV 01, 2018 | 12:00 AM
Kinetic antibody internalization assays using live-cell analysisMonoclonal antibodies (mAb) and antibody-drug conjugates (ADCs) are widely used biological therapeutics. A key property of...
NOV 01, 2018 | 12:00 AM
Integrated protocols and live-cell analysis solutions for different 3D tumor modelsIn the search for greater clinical translation, cancer researchers are increasingly turning to more comp...
OCT 24, 2018 | 12:00 PM
Ion mobility-mass spectrometry (IM-MS) is a rapid, gas-phase separation technique that has become an integral part of the analytical repertoire of techniques for the -omics. This method coupl...
OCT 24, 2018 | 9:00 AM
Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of co...
