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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • AUG 23, 2023 | 10:00 AM
      Emerging role of neuroinflammation in C9orf72-ALS
      Emerging role of neuroinflammation in C9orf72-ALS
      C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
      Speaker: Deepti Lall, PhD
      Sponsored By: Miltenyi Biotec
      16
      AUG 10, 2023 | 8:00 AM
      Current Landscape and Future Directions of Multi-specific Antibodies
      Current Landscape and Future Directions of Multi-specific Antibodies
      Antibody therapeutics is a fast-growing market boosted by developments in bispecific antibodies and in newly emerging tetra-specific antibodies. With the ability to recruit a combination of...
      Speaker: Shebna Massey, PhD
      Sponsored By: Sino Biological
      14
      AUG 01, 2023 | 10:00 PM
      Unraveling the Potential of Neural Stem Cells: Antibodies as Key Tools
      Unraveling the Potential of Neural Stem Cells: Antibodies as Key...
      Stem cells have the capability to develop into any specialized cell type, which makes them a valuable resource in research and regenerative medicine. Differentiated stem cell models provide...
      Speaker: Jamuna KS
      Sponsored By: Thermo Fisher Scientific
      33
      JUL 26, 2023 | 2:30 PM
      Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
      Serine-129 phosphorylation of α-synuclein is an activity-dependent...
      Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
      Speaker: Dr. Leonardo Parra-Rivas
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 26, 2023 | 12:15 PM
      Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
      Advancing Protein Stabilization Therapeutic Development and DUBTAC...
      Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
      Speaker: Dr. Yongli Shan
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 26, 2023 | 11:20 AM
      CD3ζ as a novel integration site for reprogramming immune cells with Chimeric Antigen Receptors
      CD3ζ as a novel integration site for reprogramming immune cells...
      Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...
      Speaker: Dr. Dimitrios L. Wagner
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 20, 2023 | 9:00 AM
      The Future of Antibody Drug Discovery: From Target Validation to Candidate Selection
      The Future of Antibody Drug Discovery: From Target Validation...
      This webinar will provide an overview of the antibody discovery process, from target validation to candidate selection, highlighting the critical steps involved in developing effective antib...
      Speaker: Sanjay Saraf , Vega Shah, PhD
      Sponsored By: Benchling
      18
      JUL 18, 2023 | 12:00 PM
      Advancing HSC research
      Advancing HSC research
      While HSC research holds immense potential for regenerative medicine and disease treatment, the field poses significant challenges. Successful isolation and purification — and the abil...
      Speaker: Richard Yao
      Sponsored By: Miltenyi Biotec
      12
      JUN 15, 2023 | 10:00 AM
      Expanding the frontiers of gene editing: the role of genotypic confirmation
      Expanding the frontiers of gene editing: the role of genotypic...
      Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      18
      JUN 14, 2023 | 8:00 AM
      Expanding the frontiers of gene editing: the role of genotypic confirmation
      Expanding the frontiers of gene editing: the role of genotypic...
      Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      MAY 09, 2023 | 1:00 PM
      Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating the biology of cell-in-cell structures in the human liver using a range of microscopy modalities
      Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating...
      Date: May 09, 2023 Time: 5:00am (PDT), 8:00pm (EDT), 2:00pm (CEST) Advances in high content imaging (HCI) have improved the use of cell culture to make a large number of comparisons within i...
      Speaker: Scott Davies, PhD, MRes, MSci
      Sponsored By: Thermo Fisher Scientific
      10
      MAR 30, 2023 | 8:00 AM
      Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as a Novel Mitochondrial Regulator and Biomarker in Breast Cancer
      Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as...
      Date: March 30, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join the Gibco Cell Culture Heroes webinar featuring Heather Beasley, PhD as she presents "SLC25A46 as a Novel Mitoc...
      Speaker: Heather Beasley, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      21
      MAR 16, 2023 | 8:00 AM
      Studying protein polymerization with mass photometry
      Studying protein polymerization with mass photometry
      Date: March 16, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Protein polymerization underpins major biological processes, such as cell division and intracellular transport, while und...
      Speaker: Nikolas Hundt
      Sponsored By: Refeyn
      20
      MAR 08, 2023 | 9:00 AM
      Boost microbial detection sensitivity with unbiased human host DNA and RNA depletion
      Boost microbial detection sensitivity with unbiased human host...
      Date: March 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) An unbiased characterization of the human microbiome is crucial to a more complete understanding of microbial effect on h...
      Speaker: Zenas George, Ph.D.
      Sponsored By: Jumpcode Genomics
      8
      MAR 08, 2023 | 8:00 AM
      Considerations to Limit Off-Target Edits in your Gene Editing Experiments
      Considerations to Limit Off-Target Edits in your Gene Editing...
      Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
      Speaker: Kevin Pridham
      Sponsored By: Thermo Fisher Scientific
      12
      MAR 08, 2023 | 7:30 AM
      Keynote Presentation: Improving Research Translation in Dementia: Humanized Mouse Models, Cognition and Imaging with Live Q&A
      Keynote Presentation: Improving Research Translation in Dementia:...
      Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
      Speaker: Marco A.M. Prado, Pharm, MSc, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      4
      MAR 08, 2023 | 6:00 AM
      Understanding the Role of Alzheimer's Disease Pathologies in Spatial Memory Dysfunction
      Understanding the Role of Alzheimer's Disease Pathologies in Spatial...
      Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
      Speaker: Abid Hussaini, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      2
      MAR 08, 2023 | 6:00 AM
      Novel Tools for Drug Discovery in Neurodegenerative Diseases
      Novel Tools for Drug Discovery in Neurodegenerative Diseases
      Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Both diseases are characterized by abnormal aggregates in the brain, which incl...
      Speaker: Jacob McPhail, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      3
      FEB 22, 2023 | 5:30 AM
      Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
      Bridging the Gap - How Human Microphysiological Systems Improve...
      Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
      Speaker: Raul Silva
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      FEB 21, 2023 | 8:00 AM
      Next generation pan-cancer blood proteome profiling using proximity extension assay
      Next generation pan-cancer blood proteome profiling using proximity...
      Date: February 21, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Cancer is a highly heterogeneous disease in need of accurate and non-invasive diagnostic tools. Here, we describe a no...
      Speaker: Prof. Mathias Uhlén, PhD
      Sponsored By: Olink Proteomics
      16
      DEC 07, 2022 | 9:00 AM
      Gibco Cell Culture Heroes: 60th Anniversary Edition
      Gibco Cell Culture Heroes: 60th Anniversary Edition
      Date: December 07, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Join us for an exciting live panel webinar, as we celebrate the 60th anniversary of Gibco Cell Culture. The panelists...
      Speaker: Jessica Hess , Rukia Henry , Ernesto Goulart , Ameet Chimote, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      20
      NOV 16, 2022 | 7:00 PM
      Innovation in Science and Technology: Translating Cellular Therapies from Bench to Bedside
      Innovation in Science and Technology: Translating Cellular Therapies...
      Date: November 16, 2022 Time: 2:00pm (AEST) Date: November 17, 2022 7:00pm (PST), 10:00pm (EST), 4:00am (CET) The growth in FDA-approved cell and gene therapy products for the treatment of d...
      Speaker: Khalid Shah , Jean Qiu
      Sponsored By: Revvity
      26
      NOV 15, 2022 | 9:00 AM
      Reverse engineering the human heart with pluripotent stem cells
      Reverse engineering the human heart with pluripotent stem cells
      Date: November 15, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Recent advances in stem cell technologies, synthetic development and organoid biology are enabling us to create more a...
      Speaker: Aitor Aguirre, PhD
      Sponsored By: BPS Bioscience
      14
      NOV 08, 2022 | 11:00 AM
      Thinking translational: Things to consider in CAR T cell workflows
      Thinking translational: Things to consider in CAR T cell workflows
      Date: November 08, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CET) Developing safe and effective CAR T cell therapies is a challenging task. That’s why thinking translational earl...
      Speaker: Robert Davies
      Sponsored By: Miltenyi Biotec
      9
    AUG 23, 2023 | 10:00 AM
    Emerging role of neuroinflammation in C9orf72-ALS
    Emerging role of neuroinflammation in C9orf72-ALS
    C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
    Speaker: Deepti Lall, PhD
    Sponsored By: Miltenyi Biotec
    16
    AUG 10, 2023 | 8:00 AM
    Current Landscape and Future Directions of Multi-specific Antibodies
    Current Landscape and Future Directions of Multi-specific Antibodies
    Antibody therapeutics is a fast-growing market boosted by developments in bispecific antibodies and in newly emerging tetra-specific antibodies. With the ability to recruit a combination of...
    Speaker: Shebna Massey, PhD
    Sponsored By: Sino Biological
    14
    AUG 01, 2023 | 10:00 PM
    Unraveling the Potential of Neural Stem Cells: Antibodies as Key Tools
    Unraveling the Potential of Neural Stem Cells: Antibodies as Key...
    Stem cells have the capability to develop into any specialized cell type, which makes them a valuable resource in research and regenerative medicine. Differentiated stem cell models provide...
    Speaker: Jamuna KS
    Sponsored By: Thermo Fisher Scientific
    33
    JUL 26, 2023 | 2:30 PM
    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
    Serine-129 phosphorylation of α-synuclein is an activity-dependent...
    Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
    Speaker: Dr. Leonardo Parra-Rivas
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    JUL 26, 2023 | 12:15 PM
    Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
    Advancing Protein Stabilization Therapeutic Development and DUBTAC...
    Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
    Speaker: Dr. Yongli Shan
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
     
     
  • JUL 26, 2023 | 11:20 AM
    CD3ζ as a novel integration site for reprogramming immune cells with Chimeric Antigen Receptors
    CD3ζ as a novel integration site for reprogramming immune cells...
    Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...
    Speaker: Dr. Dimitrios L. Wagner
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    JUL 20, 2023 | 9:00 AM
    The Future of Antibody Drug Discovery: From Target Validation to Candidate Selection
    The Future of Antibody Drug Discovery: From Target Validation...
    This webinar will provide an overview of the antibody discovery process, from target validation to candidate selection, highlighting the critical steps involved in developing effective antib...
    Speaker: Sanjay Saraf , Vega Shah, PhD
    Sponsored By: Benchling
    18
    JUL 18, 2023 | 12:00 PM
    Advancing HSC research
    Advancing HSC research
    While HSC research holds immense potential for regenerative medicine and disease treatment, the field poses significant challenges. Successful isolation and purification — and the abil...
    Speaker: Richard Yao
    Sponsored By: Miltenyi Biotec
    12
    JUN 15, 2023 | 10:00 AM
    Expanding the frontiers of gene editing: the role of genotypic confirmation
    Expanding the frontiers of gene editing: the role of genotypic...
    Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    18
    JUN 14, 2023 | 8:00 AM
    Expanding the frontiers of gene editing: the role of genotypic confirmation
    Expanding the frontiers of gene editing: the role of genotypic...
    Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    15
     
     
  • MAY 09, 2023 | 1:00 PM
    Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating the biology of cell-in-cell structures in the human liver using a range of microscopy modalities
    Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating...
    Date: May 09, 2023 Time: 5:00am (PDT), 8:00pm (EDT), 2:00pm (CEST) Advances in high content imaging (HCI) have improved the use of cell culture to make a large number of comparisons within i...
    Speaker: Scott Davies, PhD, MRes, MSci
    Sponsored By: Thermo Fisher Scientific
    10
    MAR 30, 2023 | 8:00 AM
    Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as a Novel Mitochondrial Regulator and Biomarker in Breast Cancer
    Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as...
    Date: March 30, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join the Gibco Cell Culture Heroes webinar featuring Heather Beasley, PhD as she presents "SLC25A46 as a Novel Mitoc...
    Speaker: Heather Beasley, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    21
    MAR 16, 2023 | 8:00 AM
    Studying protein polymerization with mass photometry
    Studying protein polymerization with mass photometry
    Date: March 16, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Protein polymerization underpins major biological processes, such as cell division and intracellular transport, while und...
    Speaker: Nikolas Hundt
    Sponsored By: Refeyn
    20
    MAR 08, 2023 | 9:00 AM
    Boost microbial detection sensitivity with unbiased human host DNA and RNA depletion
    Boost microbial detection sensitivity with unbiased human host...
    Date: March 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) An unbiased characterization of the human microbiome is crucial to a more complete understanding of microbial effect on h...
    Speaker: Zenas George, Ph.D.
    Sponsored By: Jumpcode Genomics
    8
    MAR 08, 2023 | 8:00 AM
    Considerations to Limit Off-Target Edits in your Gene Editing Experiments
    Considerations to Limit Off-Target Edits in your Gene Editing...
    Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
    Speaker: Kevin Pridham
    Sponsored By: Thermo Fisher Scientific
    12
     
     
  • MAR 08, 2023 | 7:30 AM
    Keynote Presentation: Improving Research Translation in Dementia: Humanized Mouse Models, Cognition and Imaging with Live Q&A
    Keynote Presentation: Improving Research Translation in Dementia:...
    Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
    Speaker: Marco A.M. Prado, Pharm, MSc, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    4
    MAR 08, 2023 | 6:00 AM
    Understanding the Role of Alzheimer's Disease Pathologies in Spatial Memory Dysfunction
    Understanding the Role of Alzheimer's Disease Pathologies in Spatial...
    Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
    Speaker: Abid Hussaini, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    2
    MAR 08, 2023 | 6:00 AM
    Novel Tools for Drug Discovery in Neurodegenerative Diseases
    Novel Tools for Drug Discovery in Neurodegenerative Diseases
    Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Both diseases are characterized by abnormal aggregates in the brain, which incl...
    Speaker: Jacob McPhail, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    3
    FEB 22, 2023 | 5:30 AM
    Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
    Bridging the Gap - How Human Microphysiological Systems Improve...
    Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
    Speaker: Raul Silva
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
    FEB 21, 2023 | 8:00 AM
    Next generation pan-cancer blood proteome profiling using proximity extension assay
    Next generation pan-cancer blood proteome profiling using proximity...
    Date: February 21, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Cancer is a highly heterogeneous disease in need of accurate and non-invasive diagnostic tools. Here, we describe a no...
    Speaker: Prof. Mathias Uhlén, PhD
    Sponsored By: Olink Proteomics
    16
     
     
  • DEC 07, 2022 | 9:00 AM
    Gibco Cell Culture Heroes: 60th Anniversary Edition
    Gibco Cell Culture Heroes: 60th Anniversary Edition
    Date: December 07, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Join us for an exciting live panel webinar, as we celebrate the 60th anniversary of Gibco Cell Culture. The panelists...
    Speaker: Jessica Hess , Rukia Henry , Ernesto Goulart , Ameet Chimote, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    20
    NOV 16, 2022 | 7:00 PM
    Innovation in Science and Technology: Translating Cellular Therapies from Bench to Bedside
    Innovation in Science and Technology: Translating Cellular Therapies...
    Date: November 16, 2022 Time: 2:00pm (AEST) Date: November 17, 2022 7:00pm (PST), 10:00pm (EST), 4:00am (CET) The growth in FDA-approved cell and gene therapy products for the treatment of d...
    Speaker: Khalid Shah , Jean Qiu
    Sponsored By: Revvity
    26
    NOV 15, 2022 | 9:00 AM
    Reverse engineering the human heart with pluripotent stem cells
    Reverse engineering the human heart with pluripotent stem cells
    Date: November 15, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Recent advances in stem cell technologies, synthetic development and organoid biology are enabling us to create more a...
    Speaker: Aitor Aguirre, PhD
    Sponsored By: BPS Bioscience
    14
    NOV 08, 2022 | 11:00 AM
    Thinking translational: Things to consider in CAR T cell workflows
    Thinking translational: Things to consider in CAR T cell workflows
    Date: November 08, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CET) Developing safe and effective CAR T cell therapies is a challenging task. That’s why thinking translational earl...
    Speaker: Robert Davies
    Sponsored By: Miltenyi Biotec
    9
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