Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.
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C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
Antibody therapeutics is a fast-growing market boosted by developments in bispecific antibodies and in newly emerging tetra-specific antibodies. With the ability to recruit a combination of...
Stem cells have the capability to develop into any specialized cell type, which makes them a valuable resource in research and regenerative medicine. Differentiated stem cell models provide...
Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...
This webinar will provide an overview of the antibody discovery process, from target validation to candidate selection, highlighting the critical steps involved in developing effective antib...
While HSC research holds immense potential for regenerative medicine and disease treatment, the field poses significant challenges. Successful isolation and purification — and the abil...
Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
Date: May 09, 2023 Time: 5:00am (PDT), 8:00pm (EDT), 2:00pm (CEST) Advances in high content imaging (HCI) have improved the use of cell culture to make a large number of comparisons within i...
Date: March 30, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join the Gibco Cell Culture Heroes webinar featuring Heather Beasley, PhD as she presents "SLC25A46 as a Novel Mitoc...
Date: March 16, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Protein polymerization underpins major biological processes, such as cell division and intracellular transport, while und...
Date: March 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) An unbiased characterization of the human microbiome is crucial to a more complete understanding of microbial effect on h...
Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...