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    Drug Resistance

    Drug Resistance refers to microorganisms mutates and becomes insensitive to a drug that was previously effective. The term is used in the context of resistance that pathogens or cancers have "acquired", that is, resistance has evolved.

    Webinars

    • AUG 06, 2020 | 12:00 AM
      From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      From biochemical nanosensors to imaging to informatics to COVID-19...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
      Causes and consequences of rapid cancer cell adaptation to therapeutic...
      Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
      Speaker: Sabrina Spencer, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 29, 2020 | 1:00 PM
      Using quantitative imaging microscopy to explore and target the molecular origins of cancer
      Using quantitative imaging microscopy to explore and target the...
      The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
      Speaker: Kirk McManus, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      MAY 14, 2020 | 12:00 AM
      Animal Models for Tuberculosis Research
      Animal Models for Tuberculosis Research
      Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
      Speaker: Yong Cheng, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      2
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      MAY 05, 2020 | 9:00 AM
      The Pharmacogenomics Behind the Investigational Treatments of COVID-19 and its High-Risk Underlying Conditions
      The Pharmacogenomics Behind the Investigational Treatments of...
      DATE: May 5, 2020 TIME: 9:00am PT As of May 4, 2020, 1,152,372 total COVID-19 cases and 67,456 total deaths have been reported in the United States (U.S.)...
      Speaker: Becky Winslow, BS, PharmD
      Sponsored By: Admera Health
      26 2
      APR 29, 2020 | 6:00 AM
      Developing novel serosurveillance tools to monitor declining infection in the malaria elimination age
      Developing novel serosurveillance tools to monitor declining infection...
      Background and aim: Worldwide malaria cases have declined. However, despite recent advances, resistance to front line drugs and insecticides means the burden remains high (219 million cases...
      Speaker: Kevin Tetteh, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      2
      APR 29, 2020 | 6:00 AM
      Development of xMAP based assays for food and environmental safety
      Development of xMAP based assays for food and environmental safety
      In order to emit less contaminants into the environment, and at the same time produce healthier foods that are free of those contaminants, all production systems should be investigated, i.e....
      Speaker: Jeroen Peters, MSc
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      4
      APR 23, 2020 | 10:30 AM
      Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
      Keynote Presentation: Systematic identification of therapeutic...
      Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
      Speaker: Kris C. Wood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      MAR 31, 2020 | 9:00 AM
      Impact of liquid biopsy in advanced HER2+ breast cancer tumors: a follow-up study
      Impact of liquid biopsy in advanced HER2+ breast cancer tumors:...
      DATE: March 31, 2020 TIME: 9:00am PT, 12:00pm ET HER2-positive breast cancer is a type of breast cancer caused by over-expression of a protein called human epidermal growth factor receptor 2...
      Speaker: Matteo Allegretti, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent, Thermo Fisher Scientific - Applied Biosystems
      7
      MAR 25, 2020 | 6:00 AM
      Metabolomics: An Evolving Approach to Cannabis Breeding
      Metabolomics: An Evolving Approach to Cannabis Breeding
      Household produce varieties such as ‘Red Delicious,’ ‘Campari,’ and ‘Earlidew’ have been selectively bred and have been enhanced for flavor since the 1990...
      Speaker: Caleb King
      Presented at: Cannabis Sciences Virtual Event Series 2020
      2
      MAR 11, 2020 | 1:30 PM
      PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary Consortium Utilizing Human Single-Neuron Recordings
      PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary...
      Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
      Speaker: Adam Mamelak, MD , Ueli Rutishauser, PhD , Gabriel Kreiman, PhD , Jie Zheng, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 03, 2020 | 9:00 AM
      The Importance of CPO Carriers Within the Healthcare System
      The Importance of CPO Carriers Within the Healthcare System
      DATE: March 3, 2020 TIME: 9:00am PT, 12:00pm ET Despite the advances of new drugs and the lowering of carbapenem breakpoints to enhance detection of CRE, there should be no complacency about...
      Speaker: Kenneth Thomson, PhD
      Presented at: BD MAX Webinar Library
      Sponsored By: BD
      5 1
      FEB 26, 2020 | 7:30 AM
      Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
      Keynote Presentation: Emerging Drug Combinations: Evolution From...
      Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
      Speaker: Khyati Shah, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      FEB 26, 2020 | 6:00 AM
      Keynote Presentation: Discovery and Development of a Novel First-in-Class Resuscitative Agent
      Keynote Presentation: Discovery and Development of a Novel First-in-Class...
      Centhaquine (previously used names, centhaquin and PMZ-2010; International Non-proprietary Name (INN) recently approved by WHO is centhaquine) is being developed by us as a first-in-class re...
      Speaker: Professor Anil Gulati, MD, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      2
      FEB 13, 2020 | 7:30 PM
      Introducing Flow Cytometry-assisted Antimicrobial Susceptibility Testing (FAST)
      Introducing Flow Cytometry-assisted Antimicrobial Susceptibility...
      DATE: February 14, 2020 TIME: 11:30am SGT, 2:30pm AET Antimicrobial resistance is a growing threat to the health and safety of the world’s population. The World Health Organisation rec...
      Speaker: Tim Inglis, PhD
      Sponsored By: Thermo Fisher Scientific
      4 1
      FEB 13, 2020 | 10:00 AM
      Introducing Flow Cytometry-assisted Antimicrobial Susceptibility Testing (FAST)
      Introducing Flow Cytometry-assisted Antimicrobial Susceptibility...
      DATE: February 13, 2020 TIME: 10:00am PST Antimicrobial resistance is a growing threat to the health and safety of the world’s population. The World Health Organisation recognizes fast...
      Speaker: Tim Inglis, PhD
      Sponsored By: Thermo Fisher Scientific
      12
      FEB 13, 2020 | 1:00 AM
      Introducing Flow Cytometry-assisted Antimicrobial Susceptibility Testing (FAST)
      Introducing Flow Cytometry-assisted Antimicrobial Susceptibility...
      DATE: February 13, 2020 TIME: 10:00am CET...
      Speaker: Tim Inglis, PhD
      Sponsored By: Thermo Fisher Scientific
      6
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      DEC 12, 2019 | 9:00 AM
      Psychiatric Pharmacogenomics: Practical Applications for the Community Psychiatrist
      Psychiatric Pharmacogenomics: Practical Applications for the Community...
      DATE: December 12 2019TIME: 9:00am PT, 12:00pm ET The Community Psychiatrist is at the vanguard of the mental health crisis afflicting the nation, providing care to the patien...
      Speaker: Joachim Benitez, MD
      19 2
      NOV 06, 2019 | 10:30 AM
      Drug discovery and pharmacology of antivirals targeting drug-resistant influenza viruses
      Drug discovery and pharmacology of antivirals targeting drug-resistant...
      The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
      Speaker: Jun Wang, PhD
      Presented at: Influenza Virtual Event Series 2019
      6
      OCT 10, 2019 | 1:30 PM
      Precision oncology: Biomarkers for treatment selection in metastatic castration resistant prostate cancer
      Precision oncology: Biomarkers for treatment selection in metastatic...
      Metastatic castration resistant prostate cancer (mCRPC) refractory to secondary hormonal treatments such as enzalutamide or abiraterone acetate are the most lethal of prostate cancers. In thi...
      Speaker: Tian Zhang, MD, MHS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      OCT 10, 2019 | 9:00 AM
      Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
      Dynamic evolution of unstable genomes: insights from in vitro...
      Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
      Speaker: Cheng-Zhong Zhang, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      OCT 09, 2019 | 7:30 AM
      Keynote Presentation: Pairing protein profiling with drug screens uncovers an effective therapy against high risk leukemia
      Keynote Presentation: Pairing protein profiling with drug screens...
      Acute lymphoblastic leukemia is the most common cancer in children and adolescents. While current treatments have resulted in 85-90% cure, the remaining 10-15% cases represent the leading cau...
      Speaker: Ernesto Diaz-Flores, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      2
    AUG 06, 2020 | 12:00 AM
    From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    From biochemical nanosensors to imaging to informatics to COVID-19...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
    Causes and consequences of rapid cancer cell adaptation to therapeutic...
    Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
    Speaker: Sabrina Spencer, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 29, 2020 | 1:00 PM
    Using quantitative imaging microscopy to explore and target the molecular origins of cancer
    Using quantitative imaging microscopy to explore and target the...
    The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
    Speaker: Kirk McManus, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    MAY 14, 2020 | 12:00 AM
    Animal Models for Tuberculosis Research
    Animal Models for Tuberculosis Research
    Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
    Speaker: Yong Cheng, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    2
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
     
     
  • MAY 05, 2020 | 9:00 AM
    The Pharmacogenomics Behind the Investigational Treatments of COVID-19 and its High-Risk Underlying Conditions
    The Pharmacogenomics Behind the Investigational Treatments of...
    DATE: May 5, 2020 TIME: 9:00am PT As of May 4, 2020, 1,152,372 total COVID-19 cases and 67,456 total deaths have been reported in the United States (U.S.)...
    Speaker: Becky Winslow, BS, PharmD
    Sponsored By: Admera Health
    26 2
    APR 29, 2020 | 6:00 AM
    Developing novel serosurveillance tools to monitor declining infection in the malaria elimination age
    Developing novel serosurveillance tools to monitor declining infection...
    Background and aim: Worldwide malaria cases have declined. However, despite recent advances, resistance to front line drugs and insecticides means the burden remains high (219 million cases...
    Speaker: Kevin Tetteh, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    2
    APR 29, 2020 | 6:00 AM
    Development of xMAP based assays for food and environmental safety
    Development of xMAP based assays for food and environmental safety
    In order to emit less contaminants into the environment, and at the same time produce healthier foods that are free of those contaminants, all production systems should be investigated, i.e....
    Speaker: Jeroen Peters, MSc
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    4
    APR 23, 2020 | 10:30 AM
    Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
    Keynote Presentation: Systematic identification of therapeutic...
    Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
    Speaker: Kris C. Wood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    MAR 31, 2020 | 9:00 AM
    Impact of liquid biopsy in advanced HER2+ breast cancer tumors: a follow-up study
    Impact of liquid biopsy in advanced HER2+ breast cancer tumors:...
    DATE: March 31, 2020 TIME: 9:00am PT, 12:00pm ET HER2-positive breast cancer is a type of breast cancer caused by over-expression of a protein called human epidermal growth factor receptor 2...
    Speaker: Matteo Allegretti, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent, Thermo Fisher Scientific - Applied Biosystems
    7
     
     
  • MAR 25, 2020 | 6:00 AM
    Metabolomics: An Evolving Approach to Cannabis Breeding
    Metabolomics: An Evolving Approach to Cannabis Breeding
    Household produce varieties such as ‘Red Delicious,’ ‘Campari,’ and ‘Earlidew’ have been selectively bred and have been enhanced for flavor since the 1990...
    Speaker: Caleb King
    Presented at: Cannabis Sciences Virtual Event Series 2020
    2
    MAR 11, 2020 | 1:30 PM
    PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary Consortium Utilizing Human Single-Neuron Recordings
    PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary...
    Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
    Speaker: Adam Mamelak, MD , Ueli Rutishauser, PhD , Gabriel Kreiman, PhD , Jie Zheng, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 03, 2020 | 9:00 AM
    The Importance of CPO Carriers Within the Healthcare System
    The Importance of CPO Carriers Within the Healthcare System
    DATE: March 3, 2020 TIME: 9:00am PT, 12:00pm ET Despite the advances of new drugs and the lowering of carbapenem breakpoints to enhance detection of CRE, there should be no complacency about...
    Speaker: Kenneth Thomson, PhD
    Presented at: BD MAX Webinar Library
    Sponsored By: BD
    5 1
    FEB 26, 2020 | 7:30 AM
    Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
    Keynote Presentation: Emerging Drug Combinations: Evolution From...
    Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
    Speaker: Khyati Shah, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    FEB 26, 2020 | 6:00 AM
    Keynote Presentation: Discovery and Development of a Novel First-in-Class Resuscitative Agent
    Keynote Presentation: Discovery and Development of a Novel First-in-Class...
    Centhaquine (previously used names, centhaquin and PMZ-2010; International Non-proprietary Name (INN) recently approved by WHO is centhaquine) is being developed by us as a first-in-class re...
    Speaker: Professor Anil Gulati, MD, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    2
     
     
  • FEB 13, 2020 | 7:30 PM
    Introducing Flow Cytometry-assisted Antimicrobial Susceptibility Testing (FAST)
    Introducing Flow Cytometry-assisted Antimicrobial Susceptibility...
    DATE: February 14, 2020 TIME: 11:30am SGT, 2:30pm AET Antimicrobial resistance is a growing threat to the health and safety of the world’s population. The World Health Organisation rec...
    Speaker: Tim Inglis, PhD
    Sponsored By: Thermo Fisher Scientific
    4 1
    FEB 13, 2020 | 10:00 AM
    Introducing Flow Cytometry-assisted Antimicrobial Susceptibility Testing (FAST)
    Introducing Flow Cytometry-assisted Antimicrobial Susceptibility...
    DATE: February 13, 2020 TIME: 10:00am PST Antimicrobial resistance is a growing threat to the health and safety of the world’s population. The World Health Organisation recognizes fast...
    Speaker: Tim Inglis, PhD
    Sponsored By: Thermo Fisher Scientific
    12
    FEB 13, 2020 | 1:00 AM
    Introducing Flow Cytometry-assisted Antimicrobial Susceptibility Testing (FAST)
    Introducing Flow Cytometry-assisted Antimicrobial Susceptibility...
    DATE: February 13, 2020 TIME: 10:00am CET...
    Speaker: Tim Inglis, PhD
    Sponsored By: Thermo Fisher Scientific
    6
    JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    DEC 12, 2019 | 9:00 AM
    Psychiatric Pharmacogenomics: Practical Applications for the Community Psychiatrist
    Psychiatric Pharmacogenomics: Practical Applications for the Community...
    DATE: December 12 2019TIME: 9:00am PT, 12:00pm ET The Community Psychiatrist is at the vanguard of the mental health crisis afflicting the nation, providing care to the patien...
    Speaker: Joachim Benitez, MD
    19 2
     
     
  • NOV 06, 2019 | 10:30 AM
    Drug discovery and pharmacology of antivirals targeting drug-resistant influenza viruses
    Drug discovery and pharmacology of antivirals targeting drug-resistant...
    The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
    Speaker: Jun Wang, PhD
    Presented at: Influenza Virtual Event Series 2019
    6
    OCT 10, 2019 | 1:30 PM
    Precision oncology: Biomarkers for treatment selection in metastatic castration resistant prostate cancer
    Precision oncology: Biomarkers for treatment selection in metastatic...
    Metastatic castration resistant prostate cancer (mCRPC) refractory to secondary hormonal treatments such as enzalutamide or abiraterone acetate are the most lethal of prostate cancers. In thi...
    Speaker: Tian Zhang, MD, MHS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    OCT 10, 2019 | 9:00 AM
    Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
    Dynamic evolution of unstable genomes: insights from in vitro...
    Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
    Speaker: Cheng-Zhong Zhang, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    OCT 09, 2019 | 7:30 AM
    Keynote Presentation: Pairing protein profiling with drug screens uncovers an effective therapy against high risk leukemia
    Keynote Presentation: Pairing protein profiling with drug screens...
    Acute lymphoblastic leukemia is the most common cancer in children and adolescents. While current treatments have resulted in 85-90% cure, the remaining 10-15% cases represent the leading cau...
    Speaker: Ernesto Diaz-Flores, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    2
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