Science continues to evolve at a rapid pace. Our understanding of laboratory animal behavior and welfare is also growing. The biomedical research community continues to receive criticisms fro...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The reproducibility of animal studies is now critical to ensure that limited resources are used wisely and that efforts yield useable knowledge. At this time, IACUCs and other similar a...
A number of elements come into the mix when trying to optimise experimental design. Among these are having clear objectives, setting up valid comparisons, knowing how to avoid bias during the...
Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Animal studies performed on behalf of GlaxoSmithKline (GSK) are expected to uphold the core principles established by Corporate Policy 403, ‘Care, Welfare and Treatment of Animals by GS...
Quality animal research is based on quality animal care and use. This is achieved by coordinating several key personnel and activities, and implementing appropriate animal care and use proced...
Background: The extracellular vesicle (EV) research field has dramatically increased in the last five years. Using a high-speed flow cytometric sorter, EVs may be isolated at high...
In Chile, the regulatory context regarding animal use in research is very poor. A legal framework for Animal Care and Use Committees is practically nonexistent. Also, the chilean culture play...
Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
The 2011 Guide for the Care and Use of Laboratory Animals has required that institutions place importance on assuring that staff working with animals are trained and competent to perform thei...
The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
Training for researchers using animals is a requirement in most European countries. However, somewhat surprisingly, the main actor in providing specific guidelines for such training is a scie...
Almost all discussion to date on the ethics of animal use in research has revolved around the balance of harms (to the animals) versus benefits (to us) associated with conducting the researc...
Malignancies caused by so-called Type I chemical and biological carcinogens provide important opportunities studying early events in cancer development, providing essential information for de...
In addition to the exciting promise that genome sequencing holds, concerns are also often described. These concerns relate to: privacy/confidentiality of findings; impact of findings on insur...
Massively parallel sequencing technology has proven to enable the identification of driver genetic alterations in patients' tumors that may be suppressed by targeted therapies. Through retros...
Our ability to view and alter biology is progressing at an exponential pace -- faster even than electronics. Next generation sequencing can be used to assess inherited, environmental and epi-...
 The Project (PersonalGenomes.org) enables open observation and critique of a large cohort "test-driving" comprehensive participatory personalized medicine. This is the only fully open-access...
Science continues to evolve at a rapid pace. Our understanding of laboratory animal behavior and welfare is also growing. The biomedical research community continues to receive criticisms fro...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The reproducibility of animal studies is now critical to ensure that limited resources are used wisely and that efforts yield useable knowledge. At this time, IACUCs and other similar a...
A number of elements come into the mix when trying to optimise experimental design. Among these are having clear objectives, setting up valid comparisons, knowing how to avoid bias during the...
Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Animal studies performed on behalf of GlaxoSmithKline (GSK) are expected to uphold the core principles established by Corporate Policy 403, ‘Care, Welfare and Treatment of Animals by GS...
Quality animal research is based on quality animal care and use. This is achieved by coordinating several key personnel and activities, and implementing appropriate animal care and use proced...
Background: The extracellular vesicle (EV) research field has dramatically increased in the last five years. Using a high-speed flow cytometric sorter, EVs may be isolated at high...
In Chile, the regulatory context regarding animal use in research is very poor. A legal framework for Animal Care and Use Committees is practically nonexistent. Also, the chilean culture play...
Adherence to strict aseptic technique is vital to all types of animal models requiring surgical intervention from both scientific and welfare perspectives. Training of both new and experience...
When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
It is well documented that social housing is fundamental to good welfare for non-human primates (NHPs). Despite this, many laboratory NHPs around the world continue to be singly housed, thoug...
The 2011 Guide for the Care and Use of Laboratory Animals has required that institutions place importance on assuring that staff working with animals are trained and competent to perform thei...
The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
Training for researchers using animals is a requirement in most European countries. However, somewhat surprisingly, the main actor in providing specific guidelines for such training is a scie...
Almost all discussion to date on the ethics of animal use in research has revolved around the balance of harms (to the animals) versus benefits (to us) associated with conducting the researc...
Malignancies caused by so-called Type I chemical and biological carcinogens provide important opportunities studying early events in cancer development, providing essential information for de...
In addition to the exciting promise that genome sequencing holds, concerns are also often described. These concerns relate to: privacy/confidentiality of findings; impact of findings on insur...
Massively parallel sequencing technology has proven to enable the identification of driver genetic alterations in patients' tumors that may be suppressed by targeted therapies. Through retros...
Our ability to view and alter biology is progressing at an exponential pace -- faster even than electronics. Next generation sequencing can be used to assess inherited, environmental and epi-...
 The Project (PersonalGenomes.org) enables open observation and critique of a large cohort "test-driving" comprehensive participatory personalized medicine. This is the only fully open-access...
Follow
