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    Genome Editing

    Genome editing: a group of technologies that give scientists the ability to alter an organism's DNA. Several approaches to genome editing have been developed.

    Webinars

    • NOV 17, 2016 | 7:00 AM
      Using patient-derived iPSCs to model and treat inherited retinal degenerative blindness
      Using patient-derived iPSCs to model and treat inherited retinal...
      Inherited retinal degenerative disorders such as retinitis pigmentosa are characterized by death of the light sensing photoreceptive neurons of the outer retina. Like the rest of the CNS, the...
      Speaker: KEYNOTE: Budd Tucker, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      6
      OCT 18, 2016 | 9:00 AM
      Genome Editing of Human Pluripotent Stem Cells to Generate Human Cellular Disease Models
      Genome Editing of Human Pluripotent Stem Cells to Generate Human...
      ...
      Speaker: Kiran Musunuru, MD, PhD, MPH
      Presented at: SyncD³ - Where drug discovery & development meet
      0
      AUG 30, 2016 | 8:00 AM
      Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
      Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
      The isolation of human embryonic stem cells (hESCs) and the discovery of human induced pluripotent stem cell (hiPSC) reprogramming have sparked a renaissance in stem cell biology, in vitro di...
      Speaker: William Hendriks
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      AUG 30, 2016 | 8:00 AM
      Delivery solutions for robust CRISPR-based genomic editing in stem cells for disease model generation
      Delivery solutions for robust CRISPR-based genomic editing in...
      Stem cells, specifically induced pluripotent stem cells (iPSCs), offer exciting potential for the future of cell therapy and regenerative medicine. More recently, genetic engineering of stem ...
      Speaker: Nektaria Andronikou
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      0
      AUG 30, 2016 | 8:00 AM
      iPSC Generation and Validation: Ensuring the best materials for downstream applications  iPSC Generation and Validation: Ensuring the best materials for downstream applications
      iPSC Generation and Validation: Ensuring the best materials for...
      The reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSC) has great potential of applications, not only in basic research, but also in drug screening and cell therapy. Wit...
      Speaker: Rene Quintanilla Jr.
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      0
      JUN 28, 2016 | 8:00 AM
      Maximizing microscopy output in cell biology: A practical guide to high content imaging & analysis
      Maximizing microscopy output in cell biology: A practical guide...
      High content imaging and analysis offers a robust, high throughput method for analyzing large numbers of cells with the benefit of the spatial and temporal demarcation afforded by fluorescenc...
      Speaker: Nicholas Dolman, Ph.D.
      Presented at: Protein and Cell Analysis Education Series
      1
      JUN 23, 2016 | 8:00 AM
      A workflow for CRISPR-Cas9 high throughput arrayed screening with synthetic crRNA
      A workflow for CRISPR-Cas9 high throughput arrayed screening with...
      DATE:  June 23, 2016 TIME:  8am Pacific time, 11am Eastern time In this webinar you will learn: Key factors in successful arrayed crRNA screening Benefits of the dual CR...
      Speaker: Louise Baskin
      Sponsored By: Dharmacon, Dharmacon
      12
      JUN 22, 2016 | 9:00 AM
      Mapping nuclear-exosome targeted poly(A) tails with 3´-RNA seq
      Mapping nuclear-exosome targeted poly(A) tails with 3´-RNA seq
      DATE: June 22, 2016 TIME: 9am Pacific time, 12pm Eastern time, 6pm Central European time A large fraction of the RNA transcribed in eukaryotic cells is rapidly degraded in the nucleus. A ...
      Speaker: Kevin Roy, PhD
      Sponsored By: Lexogen, Lexogen
      10
      MAY 12, 2016 | 10:30 AM
      DNA methylation analysis by multiplexed reduced representation bisulfite sequencing
      DNA methylation analysis by multiplexed reduced representation...
      DNA methylation is an essential mechanism of epigenetic gene regulation with broad relevance in development and disease. Its localization on genomic DNA and general stability make this epigen...
      Speaker: Paul Datlinger
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 11, 2016 | 12:00 PM
      C.E. CREDITS
      Implementing Longitudinal Clinical/Whole Genome Research
      Implementing Longitudinal Clinical/Whole Genome Research
      Technological advances have made genomic sequencing more affordable, efficient, and available. Questions related to the implementation and effects of large-scale sequencing in healthcare have...
      Speaker: Benjamin Solomon, MD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      3
      MAR 31, 2016 | 8:00 AM
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      DATE:  March 31, 2016 TIME:   8am PT, 11am ET, 4pm GMT In this webinar, you will learn:  Basics of homology-directed repair (HDR) using CRISPR-Cas9 Selection of CRISP...
      Speaker: John Schiel, Ph.D.
      Sponsored By: Dharmacon, Dharmacon
      31 12
      MAR 22, 2016 | 7:00 AM
      C.E. CREDITS
      From History to Action
      From History to Action
      Family history can be viewed as the first stop in the assessment of genetic risks for any individual. For many genetic disorders there will be no obvious signs of symptoms until significant m...
      Speaker: Bruce R. Korf, MD, PhD
      Presented at: GENETICS IN YOUR CLINIC: WHAT YOU CAN AND SHOULD DO NOW
      3 2
      FEB 24, 2016 | 1:00 PM
      From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
      From genomics to precision medicine: Uncovering and manipulating...
      Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
      Speaker: Manolis Kellis, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      JAN 21, 2016 | 8:00 AM
      How to identify key genes with CRISPR-Cas9 and shRNA screens
      How to identify key genes with CRISPR-Cas9 and shRNA screens
      DATE:  January 21, 2016 TIME:   8am Pacific time, 11am Eastern time In this webinar, you will learn:  basics of pooled lentiviral screening workflows implications of ...
      Speaker: Anja Smith, PhD
      Sponsored By: Dharmacon, Dharmacon
      18 1
      NOV 12, 2015 | 9:00 AM
      Introducing an ancestrally diverse whole genome data set for select cohort and control research applications
      Introducing an ancestrally diverse whole genome data set for select...
      Introduction and adoption of whole-genome sequencing has enabled new methods of investigation in the quest for answers in diagnostic odyssey cases as well as in the broader study of genetic d...
      Speaker: Benjamin Solomon, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      3
      OCT 01, 2015 | 9:00 AM
      RNA-editing in melanoma - Case for a sensitive analysis and interpretation platform for the resolution of a diverse molecular process and likely pathogenic variants
      RNA-editing in melanoma - Case for a sensitive analysis and interpretation...
      Of special interest in a clinical setting is the identification and interpretation of somatic variants from the DNA of a tumor/normal matched pair. Studies have shown that a large proportion...
      Speaker: Anika Joecker, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 29, 2015 | 8:00 AM
      Improve CRISPR-Cas9 experiments with rationally designed guide RNAs
      Improve CRISPR-Cas9 experiments with rationally designed guide...
      To learn more about Gene Editing watch “Webinar: CRISPR-Cas9 Gene Editing with Synthetic RNA – from start to finish!”  Attendees will learn: the importance of ...
      Speaker: Louise Baskin
      Sponsored By: Dharmacon, Dharmacon
      11 4
      SEP 16, 2015 | 7:00 AM
      Editas Medicine, Creating a novel class of genome editing therapeutics
      Editas Medicine, Creating a novel class of genome editing therapeutics
      Genome editing technologies, including the CRISPR/Cas9 system, allow for precise and corrective molecular modifications to treat the underlying cause of genetic diseases. Editas Medicine is d...
      Speaker: Vic Myer
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      2
      MAY 12, 2015 | 8:00 AM
      RNAi success in difficult-to-transfect cells by self-delivering siRNA
      RNAi success in difficult-to-transfect cells by self-delivering...
      Please click here to watch this webinar On DemandsiRNA-mediated silencing of gene expression has revolutionized the study of biology by enabling rapid and unbiased loss-of-function studies to...
      Speaker: Louise Baskin , Michael Freeley
      Sponsored By: Dharmacon, Dharmacon
      9 13
      FEB 19, 2015 | 8:00 AM
      Presenting a complete workflow - from start to finish!
      Presenting a complete workflow - from start to finish!
      For more on Gene Editing watch “Webinar: Improve CRISPR-Cas9 experiments with rationally designed guide RNAs” The CRISPR-Cas9 system is being widely used for genome engineering...
      Speaker: Emily Anderson, Ph.D.
      Sponsored By: Dharmacon, Dharmacon
      34 1
      FEB 04, 2015 | 6:00 AM
      C.E. CREDITS
      PCR testing in rodent health monitoring program: where are we exactly?
      PCR testing in rodent health monitoring program: where are we...
      Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
      Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      33
      SEP 24, 2014 | 2:00 PM
      Development and Applications of CRISPR-Cas9 for Genome Editing
      Development and Applications of CRISPR-Cas9 for Genome Editing
      The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
      Speaker: Feng Zhang, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      39
      AUG 21, 2014 | 3:00 PM
      Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
      Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
      ...
      Speaker: Piero Carninci, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      0
      AUG 21, 2014 | 11:15 AM
      Keynote: Integration of Genetics and Genomics into Medical Practice: Educational Challenges
      Keynote: Integration of Genetics and Genomics into Medical Practice:...
      Medical applications of genetics and genomics have been advancing dramatically since completion of the sequencing of the human genome. The cost of DNA sequencing has plummeted, leading to the...
      Speaker: Bruce R. Korf, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      76
    NOV 17, 2016 | 7:00 AM
    Using patient-derived iPSCs to model and treat inherited retinal degenerative blindness
    Using patient-derived iPSCs to model and treat inherited retinal...
    Inherited retinal degenerative disorders such as retinitis pigmentosa are characterized by death of the light sensing photoreceptive neurons of the outer retina. Like the rest of the CNS, the...
    Speaker: KEYNOTE: Budd Tucker, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    6
    OCT 18, 2016 | 9:00 AM
    Genome Editing of Human Pluripotent Stem Cells to Generate Human Cellular Disease Models
    Genome Editing of Human Pluripotent Stem Cells to Generate Human...
    ...
    Speaker: Kiran Musunuru, MD, PhD, MPH
    Presented at: SyncD³ - Where drug discovery & development meet
    0
    AUG 30, 2016 | 8:00 AM
    Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
    Human PSC-based disease modeling to study X-linked Dystonia-Parkinsonism
    The isolation of human embryonic stem cells (hESCs) and the discovery of human induced pluripotent stem cell (hiPSC) reprogramming have sparked a renaissance in stem cell biology, in vitro di...
    Speaker: William Hendriks
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    AUG 30, 2016 | 8:00 AM
    Delivery solutions for robust CRISPR-based genomic editing in stem cells for disease model generation
    Delivery solutions for robust CRISPR-based genomic editing in...
    Stem cells, specifically induced pluripotent stem cells (iPSCs), offer exciting potential for the future of cell therapy and regenerative medicine. More recently, genetic engineering of stem ...
    Speaker: Nektaria Andronikou
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    0
    AUG 30, 2016 | 8:00 AM
    iPSC Generation and Validation: Ensuring the best materials for downstream applications  iPSC Generation and Validation: Ensuring the best materials for downstream applications
    iPSC Generation and Validation: Ensuring the best materials for...
    The reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSC) has great potential of applications, not only in basic research, but also in drug screening and cell therapy. Wit...
    Speaker: Rene Quintanilla Jr.
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    0
     
     
  • JUN 28, 2016 | 8:00 AM
    Maximizing microscopy output in cell biology: A practical guide to high content imaging & analysis
    Maximizing microscopy output in cell biology: A practical guide...
    High content imaging and analysis offers a robust, high throughput method for analyzing large numbers of cells with the benefit of the spatial and temporal demarcation afforded by fluorescenc...
    Speaker: Nicholas Dolman, Ph.D.
    Presented at: Protein and Cell Analysis Education Series
    1
    JUN 23, 2016 | 8:00 AM
    A workflow for CRISPR-Cas9 high throughput arrayed screening with synthetic crRNA
    A workflow for CRISPR-Cas9 high throughput arrayed screening with...
    DATE:  June 23, 2016 TIME:  8am Pacific time, 11am Eastern time In this webinar you will learn: Key factors in successful arrayed crRNA screening Benefits of the dual CR...
    Speaker: Louise Baskin
    Sponsored By: Dharmacon, Dharmacon
    12
    JUN 22, 2016 | 9:00 AM
    Mapping nuclear-exosome targeted poly(A) tails with 3´-RNA seq
    Mapping nuclear-exosome targeted poly(A) tails with 3´-RNA seq
    DATE: June 22, 2016 TIME: 9am Pacific time, 12pm Eastern time, 6pm Central European time A large fraction of the RNA transcribed in eukaryotic cells is rapidly degraded in the nucleus. A ...
    Speaker: Kevin Roy, PhD
    Sponsored By: Lexogen, Lexogen
    10
    MAY 12, 2016 | 10:30 AM
    DNA methylation analysis by multiplexed reduced representation bisulfite sequencing
    DNA methylation analysis by multiplexed reduced representation...
    DNA methylation is an essential mechanism of epigenetic gene regulation with broad relevance in development and disease. Its localization on genomic DNA and general stability make this epigen...
    Speaker: Paul Datlinger
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 11, 2016 | 12:00 PM
    C.E. CREDITS
    Implementing Longitudinal Clinical/Whole Genome Research
    Implementing Longitudinal Clinical/Whole Genome Research
    Technological advances have made genomic sequencing more affordable, efficient, and available. Questions related to the implementation and effects of large-scale sequencing in healthcare have...
    Speaker: Benjamin Solomon, MD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    3
     
     
  • MAR 31, 2016 | 8:00 AM
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    DATE:  March 31, 2016 TIME:   8am PT, 11am ET, 4pm GMT In this webinar, you will learn:  Basics of homology-directed repair (HDR) using CRISPR-Cas9 Selection of CRISP...
    Speaker: John Schiel, Ph.D.
    Sponsored By: Dharmacon, Dharmacon
    31 12
    MAR 22, 2016 | 7:00 AM
    C.E. CREDITS
    From History to Action
    From History to Action
    Family history can be viewed as the first stop in the assessment of genetic risks for any individual. For many genetic disorders there will be no obvious signs of symptoms until significant m...
    Speaker: Bruce R. Korf, MD, PhD
    Presented at: GENETICS IN YOUR CLINIC: WHAT YOU CAN AND SHOULD DO NOW
    3 2
    FEB 24, 2016 | 1:00 PM
    From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
    From genomics to precision medicine: Uncovering and manipulating...
    Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
    Speaker: Manolis Kellis, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    JAN 21, 2016 | 8:00 AM
    How to identify key genes with CRISPR-Cas9 and shRNA screens
    How to identify key genes with CRISPR-Cas9 and shRNA screens
    DATE:  January 21, 2016 TIME:   8am Pacific time, 11am Eastern time In this webinar, you will learn:  basics of pooled lentiviral screening workflows implications of ...
    Speaker: Anja Smith, PhD
    Sponsored By: Dharmacon, Dharmacon
    18 1
    NOV 12, 2015 | 9:00 AM
    Introducing an ancestrally diverse whole genome data set for select cohort and control research applications
    Introducing an ancestrally diverse whole genome data set for select...
    Introduction and adoption of whole-genome sequencing has enabled new methods of investigation in the quest for answers in diagnostic odyssey cases as well as in the broader study of genetic d...
    Speaker: Benjamin Solomon, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    3
     
     
  • OCT 01, 2015 | 9:00 AM
    RNA-editing in melanoma - Case for a sensitive analysis and interpretation platform for the resolution of a diverse molecular process and likely pathogenic variants
    RNA-editing in melanoma - Case for a sensitive analysis and interpretation...
    Of special interest in a clinical setting is the identification and interpretation of somatic variants from the DNA of a tumor/normal matched pair. Studies have shown that a large proportion...
    Speaker: Anika Joecker, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 29, 2015 | 8:00 AM
    Improve CRISPR-Cas9 experiments with rationally designed guide RNAs
    Improve CRISPR-Cas9 experiments with rationally designed guide...
    To learn more about Gene Editing watch “Webinar: CRISPR-Cas9 Gene Editing with Synthetic RNA – from start to finish!”  Attendees will learn: the importance of ...
    Speaker: Louise Baskin
    Sponsored By: Dharmacon, Dharmacon
    11 4
    SEP 16, 2015 | 7:00 AM
    Editas Medicine, Creating a novel class of genome editing therapeutics
    Editas Medicine, Creating a novel class of genome editing therapeutics
    Genome editing technologies, including the CRISPR/Cas9 system, allow for precise and corrective molecular modifications to treat the underlying cause of genetic diseases. Editas Medicine is d...
    Speaker: Vic Myer
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    2
    MAY 12, 2015 | 8:00 AM
    RNAi success in difficult-to-transfect cells by self-delivering siRNA
    RNAi success in difficult-to-transfect cells by self-delivering...
    Please click here to watch this webinar On DemandsiRNA-mediated silencing of gene expression has revolutionized the study of biology by enabling rapid and unbiased loss-of-function studies to...
    Speaker: Louise Baskin , Michael Freeley
    Sponsored By: Dharmacon, Dharmacon
    9 13
    FEB 19, 2015 | 8:00 AM
    Presenting a complete workflow - from start to finish!
    Presenting a complete workflow - from start to finish!
    For more on Gene Editing watch “Webinar: Improve CRISPR-Cas9 experiments with rationally designed guide RNAs” The CRISPR-Cas9 system is being widely used for genome engineering...
    Speaker: Emily Anderson, Ph.D.
    Sponsored By: Dharmacon, Dharmacon
    34 1
     
     
  • FEB 04, 2015 | 6:00 AM
    C.E. CREDITS
    PCR testing in rodent health monitoring program: where are we exactly?
    PCR testing in rodent health monitoring program: where are we...
    Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
    Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    33
    SEP 24, 2014 | 2:00 PM
    Development and Applications of CRISPR-Cas9 for Genome Editing
    Development and Applications of CRISPR-Cas9 for Genome Editing
    The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
    Speaker: Feng Zhang, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    39
    AUG 21, 2014 | 3:00 PM
    Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
    Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
    ...
    Speaker: Piero Carninci, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    0
    AUG 21, 2014 | 11:15 AM
    Keynote: Integration of Genetics and Genomics into Medical Practice: Educational Challenges
    Keynote: Integration of Genetics and Genomics into Medical Practice:...
    Medical applications of genetics and genomics have been advancing dramatically since completion of the sequencing of the human genome. The cost of DNA sequencing has plummeted, leading to the...
    Speaker: Bruce R. Korf, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    76
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