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    Hippocampus

    The hippocampus has a unique shape, similar to that of a horseshoe. It not only assists with the storage of long term memories, but is also responsible for the memory of the location of objects or people. We would not even be able to remember where our house is without the work of the hippocampus. Alzheimer's disease, (a disease that affects elderly people and often results in loss of memory) has been proven to have affected and damaged this area of the brain.

    Webinars

    • MAR 08, 2023 | 6:00 AM
      Understanding the Role of Alzheimer's Disease Pathologies in Spatial Memory Dysfunction
      Understanding the Role of Alzheimer's Disease Pathologies in Spatial...
      Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
      Speaker: Abid Hussaini, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      2
      SEP 27, 2022 | 10:00 AM
      Spatial Single Cell Characterization of Alzheimer's Disease in Mouse and Human Hippocampus
      Spatial Single Cell Characterization of Alzheimer's Disease in...
      Date: September 27, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Alzheimer’s disease is the most common cause of dementia and the seventh leading cause of death in the United...
      Speaker: Vikram Devgan , Miranda Orr
      Sponsored By: NanoString Technologies
      10
      APR 20, 2021 | 12:00 AM
      Cell type-specific vulnerability to traumatic brain injury
      Cell type-specific vulnerability to traumatic brain injury
      Traumatic brain injury (TBI) is best characterized as brain dysfunction caused by an outside force, usually a violent blow to the head, often occurring as a result of a severe sports injury...
      Speaker: Araks Martirosyan, Ph.D.
      Presented at: Genetics Week Virtual Event Series 2021
      1
      AUG 06, 2020 | 10:00 AM
      Part VI: Dissecting Cell Signaling Networks That Regulate Adult Neural Stem Cell Functions
      Part VI: Dissecting Cell Signaling Networks That Regulate Adult...
      In the adult mammalian hippocampus, neurogenesis (in which new neurons are generated and integrated into the CNS) is believed to underlie learning and memory. Within the hippocampus, numerou...
      Speaker: Kira Mosher, PhD
      Presented at: 2020 Beckman Symposium
      1
      MAR 11, 2020 | 3:00 PM
      PANEL: Anatomical Characterization of Neuron Cell Types in the Mouse Brain
      PANEL: Anatomical Characterization of Neuron Cell Types in the...
      Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
      Speaker: Giorgio Ascoli, PhD , Hong-Wei Dong, MD, PhD , Byungkook Lim, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 9:00 AM
      PANEL: Neural circuit mechanisms of memory replay
      PANEL: Neural circuit mechanisms of memory replay
      Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
      Speaker: György Buzsáki, PhD , Attila Losonczy , Mark Schnitzer , Ivan Soltesz
      Presented at: Neuroscience Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Acoustically Targeted Molecular Neuromodulation
      Acoustically Targeted Molecular Neuromodulation
      The study of biological function in intact organisms and the development of targeted cellular therapeutics necessitate methods to image and control cellular function in vivo. Technologies su...
      Speaker: Mikhail Shapiro, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      2
      NOV 19, 2019 | 10:00 AM
      LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
      LC3-associated endocytosis: guarding against neuroinflammation...
      DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
      Speaker: Bradlee L. Heckmann, Ph.D.
      Sponsored By: Miltenyi Biotec
      6
      SEP 26, 2019 | 6:00 AM
      The reciprocal relationship between cytokine dysregulation and binge alcohol consumption
      The reciprocal relationship between cytokine dysregulation and...
      Neuroinflammation has been implicated as a factor in alcohol-induced neurodegeneration, but the role of the neuroimmune system in alcohol consumption has only recently come to the forefront....
      Speaker: S. Alex Marshall, PhD
      Presented at: Cell Biology Virtual Event Series 2019
      2
      MAR 28, 2019 | 12:00 PM
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
      Speaker: Debra Kimless, MD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      6
      FEB 27, 2019 | 8:00 AM
      Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
      Prepare for success: GMP cell banks as part of a staged, standardized,...
      DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
      Speaker: Benjamin Fryer
      Sponsored By: Thermo Fisher Scientific/Gibco
      9
      DEC 06, 2018 | 9:00 AM
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      MAR 29, 2018 | 1:30 PM
      Cannabidiol Treatment of Epilepsy and Autism Through Restoration of GABAergic Signaling
      Cannabidiol Treatment of Epilepsy and Autism Through Restoration...
      Cannabidiol (CBD) has emerged as a promising anti-epileptic drug in otherwise treatment-resistant genetic epileptic disorders. However, the clinical trials have been limited by their use of C...
      Speaker: Joshua Kaplan, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
      MAR 14, 2018 | 10:30 AM
      Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental Disorders
      Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental...
      Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
      Speaker: Chiara Manzini, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      FEB 21, 2018 | 12:00 PM
      Allosteric Modulation of Metabotropic Glutamate Receptors for the Treatment of Neurodevelopmental Disorders
      Allosteric Modulation of Metabotropic Glutamate Receptors for...
      Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
      Speaker: Colleen Niswender, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      MAR 15, 2017 | 6:00 AM
      Prefrontal control of learned fear and avoidance
      Prefrontal control of learned fear and avoidance
      We are nearing three decades of research on the neural circuits of Pavlovian fear conditioning. The advent of new techniques such as genetic and optogenetic manipulations have greatly advance...
      Speaker: Gregory Quirk, PhD
      Presented at: Neuroscience Virtual Event Series 2017
      3
      MAR 16, 2016 | 10:30 AM
      Keynote Speaker - Regulation and Function of Neurogenesis in the Adult Hippocampus
      Keynote Speaker - Regulation and Function of Neurogenesis in the...
      In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
      Speaker: Fred Gage, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      4
      MAR 18, 2015 | 12:00 PM
      Keynote - Psychosis as a Learning and Memory Disorder
      Keynote - Psychosis as a Learning and Memory Disorder
      The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
      Speaker: Carol Tamminga, MD
      Presented at: Neuroscience Virtual Event Series 2015
      10
      MAR 18, 2015 | 6:00 AM
      Keynote -Dopamine System Dysregulation in the Pathophysiology of Schizophrenia and Depression
      Keynote -Dopamine System Dysregulation in the Pathophysiology...
      The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
      Speaker: Anthony Grace, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      11
      MAR 20, 2014 | 1:00 PM
      Neurogenesis, cognitive dysfunction and Alzheimer's disease
      Neurogenesis, cognitive dysfunction and Alzheimer's disease
      Neural stem cells exist in the adult mammalian brain throughout life. They reside in the subgranular layer of the dentate gyrus and in the subventricular zone. Neural stem cells have the capa...
      Speaker: Orly Lazarov, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      124
      MAR 19, 2014 | 9:00 AM
      Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic Plasticity
      Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic...
      Dendritic spine shape enables sequestering of subcellular components needed for synaptic plasticity, including polyribosomes for local protein synthesis, smooth endoplasmic reticulum (SER) to...
      Speaker: Kristen Harris, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      24
      MAR 19, 2014 | 7:00 AM
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
      Speaker: Ahmad Salehi, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      15
    MAR 08, 2023 | 6:00 AM
    Understanding the Role of Alzheimer's Disease Pathologies in Spatial Memory Dysfunction
    Understanding the Role of Alzheimer's Disease Pathologies in Spatial...
    Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
    Speaker: Abid Hussaini, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    2
    SEP 27, 2022 | 10:00 AM
    Spatial Single Cell Characterization of Alzheimer's Disease in Mouse and Human Hippocampus
    Spatial Single Cell Characterization of Alzheimer's Disease in...
    Date: September 27, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Alzheimer’s disease is the most common cause of dementia and the seventh leading cause of death in the United...
    Speaker: Vikram Devgan , Miranda Orr
    Sponsored By: NanoString Technologies
    10
    APR 20, 2021 | 12:00 AM
    Cell type-specific vulnerability to traumatic brain injury
    Cell type-specific vulnerability to traumatic brain injury
    Traumatic brain injury (TBI) is best characterized as brain dysfunction caused by an outside force, usually a violent blow to the head, often occurring as a result of a severe sports injury...
    Speaker: Araks Martirosyan, Ph.D.
    Presented at: Genetics Week Virtual Event Series 2021
    1
    AUG 06, 2020 | 10:00 AM
    Part VI: Dissecting Cell Signaling Networks That Regulate Adult Neural Stem Cell Functions
    Part VI: Dissecting Cell Signaling Networks That Regulate Adult...
    In the adult mammalian hippocampus, neurogenesis (in which new neurons are generated and integrated into the CNS) is believed to underlie learning and memory. Within the hippocampus, numerou...
    Speaker: Kira Mosher, PhD
    Presented at: 2020 Beckman Symposium
    1
    MAR 11, 2020 | 3:00 PM
    PANEL: Anatomical Characterization of Neuron Cell Types in the Mouse Brain
    PANEL: Anatomical Characterization of Neuron Cell Types in the...
    Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
    Speaker: Giorgio Ascoli, PhD , Hong-Wei Dong, MD, PhD , Byungkook Lim, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
     
     
  • MAR 11, 2020 | 9:00 AM
    PANEL: Neural circuit mechanisms of memory replay
    PANEL: Neural circuit mechanisms of memory replay
    Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
    Speaker: György Buzsáki, PhD , Attila Losonczy , Mark Schnitzer , Ivan Soltesz
    Presented at: Neuroscience Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Acoustically Targeted Molecular Neuromodulation
    Acoustically Targeted Molecular Neuromodulation
    The study of biological function in intact organisms and the development of targeted cellular therapeutics necessitate methods to image and control cellular function in vivo. Technologies su...
    Speaker: Mikhail Shapiro, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    2
    NOV 19, 2019 | 10:00 AM
    LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
    LC3-associated endocytosis: guarding against neuroinflammation...
    DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
    Speaker: Bradlee L. Heckmann, Ph.D.
    Sponsored By: Miltenyi Biotec
    6
    SEP 26, 2019 | 6:00 AM
    The reciprocal relationship between cytokine dysregulation and binge alcohol consumption
    The reciprocal relationship between cytokine dysregulation and...
    Neuroinflammation has been implicated as a factor in alcohol-induced neurodegeneration, but the role of the neuroimmune system in alcohol consumption has only recently come to the forefront....
    Speaker: S. Alex Marshall, PhD
    Presented at: Cell Biology Virtual Event Series 2019
    2
    MAR 28, 2019 | 12:00 PM
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
    Speaker: Debra Kimless, MD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    6
     
     
  • FEB 27, 2019 | 8:00 AM
    Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
    Prepare for success: GMP cell banks as part of a staged, standardized,...
    DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
    Speaker: Benjamin Fryer
    Sponsored By: Thermo Fisher Scientific/Gibco
    9
    DEC 06, 2018 | 9:00 AM
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    MAR 29, 2018 | 1:30 PM
    Cannabidiol Treatment of Epilepsy and Autism Through Restoration of GABAergic Signaling
    Cannabidiol Treatment of Epilepsy and Autism Through Restoration...
    Cannabidiol (CBD) has emerged as a promising anti-epileptic drug in otherwise treatment-resistant genetic epileptic disorders. However, the clinical trials have been limited by their use of C...
    Speaker: Joshua Kaplan, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
    MAR 14, 2018 | 10:30 AM
    Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental Disorders
    Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental...
    Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
    Speaker: Chiara Manzini, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
    FEB 21, 2018 | 12:00 PM
    Allosteric Modulation of Metabotropic Glutamate Receptors for the Treatment of Neurodevelopmental Disorders
    Allosteric Modulation of Metabotropic Glutamate Receptors for...
    Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
    Speaker: Colleen Niswender, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
     
     
  • MAR 15, 2017 | 6:00 AM
    Prefrontal control of learned fear and avoidance
    Prefrontal control of learned fear and avoidance
    We are nearing three decades of research on the neural circuits of Pavlovian fear conditioning. The advent of new techniques such as genetic and optogenetic manipulations have greatly advance...
    Speaker: Gregory Quirk, PhD
    Presented at: Neuroscience Virtual Event Series 2017
    3
    MAR 16, 2016 | 10:30 AM
    Keynote Speaker - Regulation and Function of Neurogenesis in the Adult Hippocampus
    Keynote Speaker - Regulation and Function of Neurogenesis in the...
    In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
    Speaker: Fred Gage, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    4
    MAR 18, 2015 | 12:00 PM
    Keynote - Psychosis as a Learning and Memory Disorder
    Keynote - Psychosis as a Learning and Memory Disorder
    The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
    Speaker: Carol Tamminga, MD
    Presented at: Neuroscience Virtual Event Series 2015
    10
    MAR 18, 2015 | 6:00 AM
    Keynote -Dopamine System Dysregulation in the Pathophysiology of Schizophrenia and Depression
    Keynote -Dopamine System Dysregulation in the Pathophysiology...
    The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
    Speaker: Anthony Grace, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    11
    MAR 20, 2014 | 1:00 PM
    Neurogenesis, cognitive dysfunction and Alzheimer's disease
    Neurogenesis, cognitive dysfunction and Alzheimer's disease
    Neural stem cells exist in the adult mammalian brain throughout life. They reside in the subgranular layer of the dentate gyrus and in the subventricular zone. Neural stem cells have the capa...
    Speaker: Orly Lazarov, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    124
     
     
  • MAR 19, 2014 | 9:00 AM
    Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic Plasticity
    Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic...
    Dendritic spine shape enables sequestering of subcellular components needed for synaptic plasticity, including polyribosomes for local protein synthesis, smooth endoplasmic reticulum (SER) to...
    Speaker: Kristen Harris, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    24
    MAR 19, 2014 | 7:00 AM
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
    Speaker: Ahmad Salehi, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    15
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