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    In Vivo

    In Vivo: are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

    Webinars

    • DEC 08, 2021 | 11:00 AM
      Human Breast Organoid Models for Cancer Research
      Human Breast Organoid Models for Cancer Research
      Date: December 8, 2021 Time: 11:00am (PST), 2:00pam (EST) Breast cancer is the most common type of cancer and the leading cause of cancer deaths for women. Despite considerable ongoing resea...
      Speaker: Xiaojiang Cui, PhD
      Sponsored By: Akoya Biosciences
      12
      DEC 07, 2021 | 8:00 AM
      T Cells in COVID-19 - Translating research findings into clinical options
      T Cells in COVID-19 - Translating research findings into clinical...
      Date: November 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) Analysis of SARS-CoV-2–specific T cells is important to understand their role during acute disease and in long-term protection...
      Speaker: Lorenz Fülle, PhD , Kirsten Langeveld
      Sponsored By: Miltenyi Biotec
      10 1
      OCT 26, 2021 | 8:00 AM
      Maximizing tumor microenvironment analysis for TILs from limited patient samples
      Maximizing tumor microenvironment analysis for TILs from limited...
      Date: October 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) A complex interaction among heterogenous immune and tumor cells within the tumorous tissue not only influences tumor progression, but...
      Speaker: Dr. César Evaristo
      Sponsored By: Miltenyi Biotec
      5
      OCT 13, 2021 | 6:00 AM
      Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2 Human Monoclonal Antibodies
      Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2...
      We’ll discuss the rapid discovery efforts to identify human monoclonal antibody drugs that protect against COVID-19. We will review the technologies used to find antibodies, the optima...
      Speaker: James Crowe, MD
      Presented at: Coronavirus Series
      26
      OCT 07, 2021 | 10:00 AM
      Optimizing tumor study performance:  Evaluating the B-NDG & NSGâ„¢ models in PDX and CDX tumor studies.
      Optimizing tumor study performance: Evaluating the B-NDG & NSGâ„¢...
      Date: October 07, 2021 Time: 10:00am (PDT), 1:00pm (EDT) It's estimated than less than 10% of investigational anti-cancer drugs successfully achieve FDA approval for clinical use. This i...
      Speaker: Viktoria Hyddmark
      Sponsored By: Envigo
      3 1
      SEP 29, 2021 | 11:59 PM
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy, PhD
      Presented at: CRISPR Virtual Event Series 2021
      2 2
      SEP 29, 2021 | 11:00 AM
      Automating culture and high-content imaging of 3D organoids for in vitro assessment of compound effects
      Automating culture and high-content imaging of 3D organoids for...
      Date: Septembr 29, 2021 Time: 11:00am (PDT), 2:00pm (EDT) 3D cell models are becoming increasingly popular for studying complex biological effects, tissue functionality, and diseases. While...
      Speaker: Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      9
      SEP 08, 2021 | 8:00 AM
      Immunotoxicology assay toolbox: maximize standardization
      Immunotoxicology assay toolbox: maximize standardization
      Date: September 08, 2021 Time: 8:00am (PST), 11:00am (EST) Developing biopharmaceuticals is challenging, with safety liability remaining one of the primary reasons for failure. As such, safe...
      Speaker: Urmi Roy, PhD
      Sponsored By: Miltenyi Biotec
      5
      SEP 08, 2021 | 12:00 AM
      Development of Self-Replicating Propagation-Defective RNAs as Next Generation Vaccine Candidates Against Human Coronaviruses
      Development of Self-Replicating Propagation-Defective RNAs as...
      Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
      Speaker: Isabel Sola, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      SEP 08, 2021 | 12:00 AM
      Memory CD4 T cells established by endemic human Coronaviruses have the potential to be recruited into the response to SARS-Cov-2
      Memory CD4 T cells established by endemic human Coronaviruses...
      For centuries, humans have become infected with endemic circulating Coronaviruses (hCoV), typically repeatedly throughout life. To understand how these respiratory infections establish CD4 T...
      Speaker: Andrea J. Sant, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      AUG 25, 2021 | 12:00 AM
      A Novel Mouse Model of Ataxia Telangiectasia for Testing Small Molecule Readthrough (SMRT) Compounds
      A Novel Mouse Model of Ataxia Telangiectasia for Testing Small...
      Ataxia Telangiectasia, also known as A-T, is a devastating neuropediatric and genetic disorder for which there is no cure. Patients suffer from immune deficiency, cancer predisposition, and...
      Speaker: Paul Mathews, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
      AUG 25, 2021 | 12:00 AM
      Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic Lateral Sclerosis
      Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic...
      Over 40 tandem repeats undergo expansion events that lead to neurological disease. This number is likely an underestimate as many repeats are difficult to amplify using existing short read s...
      Speaker: Paul Valdmanis, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: PacBio
      1
      AUG 25, 2021 | 12:00 AM
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
      Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
      Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
      Speaker: Andrii Domanskyi, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      5
      JUN 24, 2021 | 8:00 AM
      Insights to Heart Development and Disease using Single-Cell Analysis and In Vitro Modeling of Pluripotent Stem Cells
      Insights to Heart Development and Disease using Single-Cell Analysis...
      Date: June 24, 2021 Time: 8:00am (PDT), 11:00am (EDT) Cardiovascular disease is a leading health problem, affecting almost 30% of individuals in the developed world, and comprises a wide ran...
      Speaker: Dr. Peter Andersen
      Sponsored By: Sony Biotechnology
      3
      JUN 08, 2021 | 8:00 AM
      Antigen-specific CD4 T cell responses in humans: SARS-CoV-2 and beyond
      Antigen-specific CD4 T cell responses in humans: SARS-CoV-2 and...
      Date: June 08, 2021 Time: 08:00am (PDT) COVID-19 displays high clinical variability, but what determines its severity is unclear. Analysis of antigen-specific T cell responses has contribu...
      Speaker: Prof. Dr. Alexander Scheffold , Felix Eppler, PhD
      Sponsored By: Miltenyi Biotec
      15
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
      APR 27, 2021 | 7:00 AM
      High Resolution Imaging of Zebrafish at Nano and Millimeter Scale
      High Resolution Imaging of Zebrafish at Nano and Millimeter Scale
      Date: April 27, 2021 Time: 7:00am (PDT), 11:00am (EDT) Visualization is an important step to address complex biological questions in vivo. The imaging process can widen the perspective of an...
      Speaker: Julien Resseguier , Claudia Florindo, PhD
      Sponsored By: Andor
      8
      FEB 24, 2021 | 1:30 PM
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
      Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      1
      FEB 24, 2021 | 12:00 PM
      Deep Mechanistic profiling of immune oncology drug combinations in cancer patients with CIVO intratumoral micro-dosing and NanoString's GeoMx® Digital Spatial Profiler
      Deep Mechanistic profiling of immune oncology drug combinations...
      With an introduction by Sarah Warren, the Senior Director of Translational Science, this webinar will open by providing a brief technology overview of NanoString Technologies. Dr. Warren wil...
      Speaker: Jason Frazier , Sarah Warren, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      Sponsored By: NanoString Technologies
      2
      FEB 24, 2021 | 10:00 AM
      Biosafety Enclosures and the Automated Lab: Steps for Success
      Biosafety Enclosures and the Automated Lab: Steps for Success
      DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
      Speaker: David Wasescha , Simon Fogarty
      Sponsored By: Labconco
      15
      FEB 24, 2021 | 12:00 AM
      Evolution of a Platform-Based Non-Clinical Safety Assessment Approach for Vaccines
      Evolution of a Platform-Based Non-Clinical Safety Assessment Approach...
      Platform based therapeutics and vaccines offer a unique opportunity to simplify and streamline the drug development process. Moderna has taken the approach of harnessing the power of mRNA as...
      Speaker: Joseph J. Senn, PhD, DABT
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      2
      FEB 24, 2021 | 12:00 AM
      The development and application of TRUPATH biosensors to the study of GPCR pharmacology and functional selectivity
      The development and application of TRUPATH biosensors to the study...
      G-protein-coupled receptors (GPCRs) remain major drug targets, despite an incomplete understanding of how they signal through 16 non-visual G-protein signal transducers (collectively named t...
      Speaker: Reid Olsen, PhD, Pharmacology, Head of GPCR Pharmacology
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      4
      FEB 10, 2021 | 12:00 AM
      Refining Pain Management for Laboratory Mice
      Refining Pain Management for Laboratory Mice
      Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
      Speaker: Paulin Jirkof, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      4
      FEB 10, 2021 | 12:00 AM
      The Experimental Design Assistant: an interactive web-based tool to provide bespoke feedback on experimental plans for in vivo studies
      The Experimental Design Assistant: an interactive web-based tool...
      There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
      Speaker: Dr. Esther Pearl
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      2
    DEC 08, 2021 | 11:00 AM
    Human Breast Organoid Models for Cancer Research
    Human Breast Organoid Models for Cancer Research
    Date: December 8, 2021 Time: 11:00am (PST), 2:00pam (EST) Breast cancer is the most common type of cancer and the leading cause of cancer deaths for women. Despite considerable ongoing resea...
    Speaker: Xiaojiang Cui, PhD
    Sponsored By: Akoya Biosciences
    12
    DEC 07, 2021 | 8:00 AM
    T Cells in COVID-19 - Translating research findings into clinical options
    T Cells in COVID-19 - Translating research findings into clinical...
    Date: November 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) Analysis of SARS-CoV-2–specific T cells is important to understand their role during acute disease and in long-term protection...
    Speaker: Lorenz Fülle, PhD , Kirsten Langeveld
    Sponsored By: Miltenyi Biotec
    10 1
    OCT 26, 2021 | 8:00 AM
    Maximizing tumor microenvironment analysis for TILs from limited patient samples
    Maximizing tumor microenvironment analysis for TILs from limited...
    Date: October 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) A complex interaction among heterogenous immune and tumor cells within the tumorous tissue not only influences tumor progression, but...
    Speaker: Dr. César Evaristo
    Sponsored By: Miltenyi Biotec
    5
    OCT 13, 2021 | 6:00 AM
    Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2 Human Monoclonal Antibodies
    Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2...
    We’ll discuss the rapid discovery efforts to identify human monoclonal antibody drugs that protect against COVID-19. We will review the technologies used to find antibodies, the optima...
    Speaker: James Crowe, MD
    Presented at: Coronavirus Series
    26
    OCT 07, 2021 | 10:00 AM
    Optimizing tumor study performance:  Evaluating the B-NDG & NSGâ„¢ models in PDX and CDX tumor studies.
    Optimizing tumor study performance: Evaluating the B-NDG & NSGâ„¢...
    Date: October 07, 2021 Time: 10:00am (PDT), 1:00pm (EDT) It's estimated than less than 10% of investigational anti-cancer drugs successfully achieve FDA approval for clinical use. This i...
    Speaker: Viktoria Hyddmark
    Sponsored By: Envigo
    3 1
     
     
  • SEP 29, 2021 | 11:59 PM
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy, PhD
    Presented at: CRISPR Virtual Event Series 2021
    2 2
    SEP 29, 2021 | 11:00 AM
    Automating culture and high-content imaging of 3D organoids for in vitro assessment of compound effects
    Automating culture and high-content imaging of 3D organoids for...
    Date: Septembr 29, 2021 Time: 11:00am (PDT), 2:00pm (EDT) 3D cell models are becoming increasingly popular for studying complex biological effects, tissue functionality, and diseases. While...
    Speaker: Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    9
    SEP 08, 2021 | 8:00 AM
    Immunotoxicology assay toolbox: maximize standardization
    Immunotoxicology assay toolbox: maximize standardization
    Date: September 08, 2021 Time: 8:00am (PST), 11:00am (EST) Developing biopharmaceuticals is challenging, with safety liability remaining one of the primary reasons for failure. As such, safe...
    Speaker: Urmi Roy, PhD
    Sponsored By: Miltenyi Biotec
    5
    SEP 08, 2021 | 12:00 AM
    Development of Self-Replicating Propagation-Defective RNAs as Next Generation Vaccine Candidates Against Human Coronaviruses
    Development of Self-Replicating Propagation-Defective RNAs as...
    Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
    Speaker: Isabel Sola, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
    SEP 08, 2021 | 12:00 AM
    Memory CD4 T cells established by endemic human Coronaviruses have the potential to be recruited into the response to SARS-Cov-2
    Memory CD4 T cells established by endemic human Coronaviruses...
    For centuries, humans have become infected with endemic circulating Coronaviruses (hCoV), typically repeatedly throughout life. To understand how these respiratory infections establish CD4 T...
    Speaker: Andrea J. Sant, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
     
     
  • AUG 25, 2021 | 12:00 AM
    A Novel Mouse Model of Ataxia Telangiectasia for Testing Small Molecule Readthrough (SMRT) Compounds
    A Novel Mouse Model of Ataxia Telangiectasia for Testing Small...
    Ataxia Telangiectasia, also known as A-T, is a devastating neuropediatric and genetic disorder for which there is no cure. Patients suffer from immune deficiency, cancer predisposition, and...
    Speaker: Paul Mathews, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    1
    AUG 25, 2021 | 12:00 AM
    Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic Lateral Sclerosis
    Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic...
    Over 40 tandem repeats undergo expansion events that lead to neurological disease. This number is likely an underestimate as many repeats are difficult to amplify using existing short read s...
    Speaker: Paul Valdmanis, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: PacBio
    1
    AUG 25, 2021 | 12:00 AM
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant and How can we Model it?
    Alpha-synuclein Aggregation in Parkinson's Disease - Is it Relevant...
    Parkinson’s disease (PD) is the second most common neurodegenerative disorder with multiple motor and non-motor symptoms. PD is characterized by the presence on proteinaceous neuronal...
    Speaker: Andrii Domanskyi, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    5
    JUN 24, 2021 | 8:00 AM
    Insights to Heart Development and Disease using Single-Cell Analysis and In Vitro Modeling of Pluripotent Stem Cells
    Insights to Heart Development and Disease using Single-Cell Analysis...
    Date: June 24, 2021 Time: 8:00am (PDT), 11:00am (EDT) Cardiovascular disease is a leading health problem, affecting almost 30% of individuals in the developed world, and comprises a wide ran...
    Speaker: Dr. Peter Andersen
    Sponsored By: Sony Biotechnology
    3
    JUN 08, 2021 | 8:00 AM
    Antigen-specific CD4 T cell responses in humans: SARS-CoV-2 and beyond
    Antigen-specific CD4 T cell responses in humans: SARS-CoV-2 and...
    Date: June 08, 2021 Time: 08:00am (PDT) COVID-19 displays high clinical variability, but what determines its severity is unclear. Analysis of antigen-specific T cell responses has contribu...
    Speaker: Prof. Dr. Alexander Scheffold , Felix Eppler, PhD
    Sponsored By: Miltenyi Biotec
    15
     
     
  • MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    APR 27, 2021 | 7:00 AM
    High Resolution Imaging of Zebrafish at Nano and Millimeter Scale
    High Resolution Imaging of Zebrafish at Nano and Millimeter Scale
    Date: April 27, 2021 Time: 7:00am (PDT), 11:00am (EDT) Visualization is an important step to address complex biological questions in vivo. The imaging process can widen the perspective of an...
    Speaker: Julien Resseguier , Claudia Florindo, PhD
    Sponsored By: Andor
    8
    FEB 24, 2021 | 1:30 PM
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
    Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    1
    FEB 24, 2021 | 12:00 PM
    Deep Mechanistic profiling of immune oncology drug combinations in cancer patients with CIVO intratumoral micro-dosing and NanoString's GeoMx® Digital Spatial Profiler
    Deep Mechanistic profiling of immune oncology drug combinations...
    With an introduction by Sarah Warren, the Senior Director of Translational Science, this webinar will open by providing a brief technology overview of NanoString Technologies. Dr. Warren wil...
    Speaker: Jason Frazier , Sarah Warren, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    Sponsored By: NanoString Technologies
    2
    FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
     
     
  • FEB 24, 2021 | 12:00 AM
    Evolution of a Platform-Based Non-Clinical Safety Assessment Approach for Vaccines
    Evolution of a Platform-Based Non-Clinical Safety Assessment Approach...
    Platform based therapeutics and vaccines offer a unique opportunity to simplify and streamline the drug development process. Moderna has taken the approach of harnessing the power of mRNA as...
    Speaker: Joseph J. Senn, PhD, DABT
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    2
    FEB 24, 2021 | 12:00 AM
    The development and application of TRUPATH biosensors to the study of GPCR pharmacology and functional selectivity
    The development and application of TRUPATH biosensors to the study...
    G-protein-coupled receptors (GPCRs) remain major drug targets, despite an incomplete understanding of how they signal through 16 non-visual G-protein signal transducers (collectively named t...
    Speaker: Reid Olsen, PhD, Pharmacology, Head of GPCR Pharmacology
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    4
    FEB 10, 2021 | 12:00 AM
    Refining Pain Management for Laboratory Mice
    Refining Pain Management for Laboratory Mice
    Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
    Speaker: Paulin Jirkof, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    4
    FEB 10, 2021 | 12:00 AM
    The Experimental Design Assistant: an interactive web-based tool to provide bespoke feedback on experimental plans for in vivo studies
    The Experimental Design Assistant: an interactive web-based tool...
    There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
    Speaker: Dr. Esther Pearl
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    2
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