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    In Vivo

    In Vivo: are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

    Webinars

    • JUL 26, 2023 | 4:45 PM
      SLEEK: A highly efficient transgene knock-in technology in clinically relevant cell types
      SLEEK: A highly efficient transgene knock-in technology in clinically...
      Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this study, we used a CRISPR nuclease that targets a site within an exon of an essential gene and de...
      Speaker: Dr. John Zuris
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      5
      JUL 26, 2023 | 12:15 PM
      Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
      Advancing Protein Stabilization Therapeutic Development and DUBTAC...
      Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
      Speaker: Dr. Yongli Shan
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 20, 2023 | 9:00 AM
      The Future of Antibody Drug Discovery: From Target Validation to Candidate Selection
      The Future of Antibody Drug Discovery: From Target Validation...
      This webinar will provide an overview of the antibody discovery process, from target validation to candidate selection, highlighting the critical steps involved in developing effective antib...
      Speaker: Sanjay Saraf , Vega Shah, PhD
      Sponsored By: Benchling
      18
      JUN 29, 2023 | 7:55 PM
      RNA Interference - From Single Gene Studies to Whole Genome Screens
      RNA Interference - From Single Gene Studies to Whole Genome Screens
      RNA interference (RNAi) offers a fast and easy system to study gene functions. However, the traditionally used small interfering RNAs (siRNAs) can exhibit pronounced and problematic off-targ...
      Speaker: Julia Krüger, PhD
      Sponsored By: MilliporeSigma
      9
      JUN 27, 2023 | 8:00 AM
      Science of Tissue Processing, Tidal vs. Rotational processing
      Science of Tissue Processing, Tidal vs. Rotational processing
      Quality sample preparation is fundamental to the analytical process. Tissue Processing is the most complex and one of the longest step in the histology workflow. The quality of the processed...
      Speaker: Andrew Lisowski
      Sponsored By: Epredia
      18
      MAY 31, 2023 | 11:00 AM
      Unveiling insights: Leveraging single-cell transcriptomics and epigenomics for biomarker discovery
      Unveiling insights: Leveraging single-cell transcriptomics and...
      Date: May 31, 2023 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CET) Single-cell genomics has facilitated the understanding of mechanisms involved in various biological processes such as tumor...
      Speaker: Dr. Derek Janssens, PhD , Dr. Ilaria Iacobucci, PhD
      Sponsored By: Takara Bio
      21
      MAY 09, 2023 | 1:00 PM
      Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating the biology of cell-in-cell structures in the human liver using a range of microscopy modalities
      Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating...
      Date: May 09, 2023 Time: 5:00am (PDT), 8:00pm (EDT), 2:00pm (CEST) Advances in high content imaging (HCI) have improved the use of cell culture to make a large number of comparisons within i...
      Speaker: Scott Davies, PhD, MRes, MSci
      Sponsored By: Thermo Fisher Scientific
      10
      MAR 30, 2023 | 5:00 PM
      Memory-rich CAR-T cell engineering by piggyBac transposon system for solid malignancies
      Memory-rich CAR-T cell engineering by piggyBac transposon system...
      Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
      Speaker: Dr. Shigeki Yagyu
      Sponsored By: MaxCyte®
      15
      MAR 30, 2023 | 8:00 AM
      Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as a Novel Mitochondrial Regulator and Biomarker in Breast Cancer
      Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as...
      Date: March 30, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join the Gibco Cell Culture Heroes webinar featuring Heather Beasley, PhD as she presents "SLC25A46 as a Novel Mitoc...
      Speaker: Heather Beasley, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      21
      MAR 22, 2023 | 6:00 AM
      Microfluidics Platforms for High Throughput In Vivo Screening
      Microfluidics Platforms for High Throughput In Vivo Screening
      Preclinical research and development are the cornerstone of modern drug discovery. A variety of biological systems including in vitro, 3D cultures, and organoids are essential tools, with ul...
      Speaker: Siva Vanapalli, PhD
      Presented at: Laboratory Automation Virtual Event Series 2023
      1
      MAR 08, 2023 | 7:30 AM
      Keynote Presentation: Improving Research Translation in Dementia: Humanized Mouse Models, Cognition and Imaging with Live Q&A
      Keynote Presentation: Improving Research Translation in Dementia:...
      Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
      Speaker: Marco A.M. Prado, Pharm, MSc, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      4
      MAR 08, 2023 | 6:00 AM
      Novel Tools for Drug Discovery in Neurodegenerative Diseases
      Novel Tools for Drug Discovery in Neurodegenerative Diseases
      Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Both diseases are characterized by abnormal aggregates in the brain, which incl...
      Speaker: Jacob McPhail, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      3
      FEB 22, 2023 | 9:00 AM
      A scalable miniature circular GenCircleâ„¢ dsDNA production system for gene and cell therapy
      A scalable miniature circular GenCircleâ„¢ dsDNA production system...
      Date: February 22, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated...
      Speaker: Dr. Fan Zhou, PhD
      Sponsored By: GenScript
      7
      FEB 22, 2023 | 5:30 AM
      Cells, Tox and Rock 'n' Roll - Cell Validation and Drug-Induced Liver Injury Using a Human Liver Microphysiological System
      Cells, Tox and Rock 'n' Roll - Cell Validation and Drug-Induced...
      Ninety percent of therapeutic agents reaching clinical trial fail to reach entry to market, with safety concerns being a major cause for failures in phase I and II clinical trials. Drug-indu...
      Speaker: Christiana Skarlatopoulou
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      FEB 22, 2023 | 5:30 AM
      Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
      Bridging the Gap - How Human Microphysiological Systems Improve...
      Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
      Speaker: Raul Silva
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      FEB 22, 2023 | 5:30 AM
      Avoiding InVivo Study Pitfalls
      Avoiding InVivo Study Pitfalls
      Learning Objectives: 1. Describe and discuss some of the unique aspect of in vivo studies. 2. Identify specific study practices to ensure high quality study data and animal welfare. 3. Discu...
      Speaker: Matthew Flegal, BS, SRS
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      1
      FEB 15, 2023 | 7:00 AM
      Scattering Microscopy: Label-Free Imaging Approaches
      Scattering Microscopy: Label-Free Imaging Approaches
      Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
      Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
      Sponsored By: Teledyne Photometrics
      28
      NOV 09, 2022 | 8:00 AM
      Addressing common challenges in lentiviral vector clarification using closed, automated counterflow centrifugation systems
      Addressing common challenges in lentiviral vector clarification...
      Date: November 09, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) The field of cell and gene therapy is rapidly growing. In particular, the use of lentiviruses in CAR-T applications is...
      Speaker: Carl Dargitz , Magda Tomala
      Sponsored By: Thermo Fisher Scientific, Sartorius
      16
      NOV 08, 2022 | 11:00 AM
      Thinking translational: Things to consider in CAR T cell workflows
      Thinking translational: Things to consider in CAR T cell workflows
      Date: November 08, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CET) Developing safe and effective CAR T cell therapies is a challenging task. That’s why thinking translational earl...
      Speaker: Robert Davies
      Sponsored By: Miltenyi Biotec
      9
      NOV 01, 2022 | 8:00 AM
      Debunking Antibody Titration Myths
      Debunking Antibody Titration Myths
      Date: November 01, 2022 Time: 8:00am (PDT), 1:00am (EDT), 4:00pm (CEST) This webinar will focus on sub-micron particle analysis utilizing high sensitivity violet side scatter detection. We w...
      Speaker: Diana Bonilla Escobar, PhD
      Sponsored By: Cytek Biosciences
      26
      OCT 19, 2022 | 10:00 AM
      Immunodeficient Mouse Models to Support Prolonged Engraftment of Human NK and Tumor Cells
      Immunodeficient Mouse Models to Support Prolonged Engraftment...
      Date: October 19, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) In this webinar, we will introduce the generation and applications of Biocytogen’s severely immunodeficient (B-N...
      Speaker: Jenna Frame
      Sponsored By: Envigo
      13
      OCT 19, 2022 | 6:00 AM
      Evolution of SARS-CoV-2
      Evolution of SARS-CoV-2
      At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), emerged in China. As of September 2022, SARS-CoV...
      Speaker: Kei Sato, PhD
      Presented at: Coronavirus Series
      6
      SEP 29, 2022 | 6:00 AM
      Reliable Antifungal Susceptibility Testing with MICRONAUT-AM according to EUCAST standards
      Reliable Antifungal Susceptibility Testing with MICRONAUT-AM according...
      Date: September 29, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CET) The global burden of candidiasis remains relatively stable. However, the epidemiology of the last ten years shows a shi...
      Speaker: Alix Coste, PhD, FAMH
      Sponsored By: Bruker Microbiology & Diagnostics
      11
      SEP 15, 2022 | 9:00 AM
      Advances and Challenges in Targeting Kinases in Cancer Therapeutics
      Advances and Challenges in Targeting Kinases in Cancer Therapeutics
      Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
      Speaker: Aishath Shanaz Naeem , Veronique Baron
      Sponsored By: BPS Bioscience
      9
    JUL 26, 2023 | 4:45 PM
    SLEEK: A highly efficient transgene knock-in technology in clinically relevant cell types
    SLEEK: A highly efficient transgene knock-in technology in clinically...
    Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this study, we used a CRISPR nuclease that targets a site within an exon of an essential gene and de...
    Speaker: Dr. John Zuris
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    5
    JUL 26, 2023 | 12:15 PM
    Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
    Advancing Protein Stabilization Therapeutic Development and DUBTAC...
    Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
    Speaker: Dr. Yongli Shan
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    JUL 20, 2023 | 9:00 AM
    The Future of Antibody Drug Discovery: From Target Validation to Candidate Selection
    The Future of Antibody Drug Discovery: From Target Validation...
    This webinar will provide an overview of the antibody discovery process, from target validation to candidate selection, highlighting the critical steps involved in developing effective antib...
    Speaker: Sanjay Saraf , Vega Shah, PhD
    Sponsored By: Benchling
    18
    JUN 29, 2023 | 7:55 PM
    RNA Interference - From Single Gene Studies to Whole Genome Screens
    RNA Interference - From Single Gene Studies to Whole Genome Screens
    RNA interference (RNAi) offers a fast and easy system to study gene functions. However, the traditionally used small interfering RNAs (siRNAs) can exhibit pronounced and problematic off-targ...
    Speaker: Julia Krüger, PhD
    Sponsored By: MilliporeSigma
    9
    JUN 27, 2023 | 8:00 AM
    Science of Tissue Processing, Tidal vs. Rotational processing
    Science of Tissue Processing, Tidal vs. Rotational processing
    Quality sample preparation is fundamental to the analytical process. Tissue Processing is the most complex and one of the longest step in the histology workflow. The quality of the processed...
    Speaker: Andrew Lisowski
    Sponsored By: Epredia
    18
     
     
  • MAY 31, 2023 | 11:00 AM
    Unveiling insights: Leveraging single-cell transcriptomics and epigenomics for biomarker discovery
    Unveiling insights: Leveraging single-cell transcriptomics and...
    Date: May 31, 2023 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CET) Single-cell genomics has facilitated the understanding of mechanisms involved in various biological processes such as tumor...
    Speaker: Dr. Derek Janssens, PhD , Dr. Ilaria Iacobucci, PhD
    Sponsored By: Takara Bio
    21
    MAY 09, 2023 | 1:00 PM
    Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating the biology of cell-in-cell structures in the human liver using a range of microscopy modalities
    Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating...
    Date: May 09, 2023 Time: 5:00am (PDT), 8:00pm (EDT), 2:00pm (CEST) Advances in high content imaging (HCI) have improved the use of cell culture to make a large number of comparisons within i...
    Speaker: Scott Davies, PhD, MRes, MSci
    Sponsored By: Thermo Fisher Scientific
    10
    MAR 30, 2023 | 5:00 PM
    Memory-rich CAR-T cell engineering by piggyBac transposon system for solid malignancies
    Memory-rich CAR-T cell engineering by piggyBac transposon system...
    Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
    Speaker: Dr. Shigeki Yagyu
    Sponsored By: MaxCyte®
    15
    MAR 30, 2023 | 8:00 AM
    Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as a Novel Mitochondrial Regulator and Biomarker in Breast Cancer
    Gibco Cell Culture Heroes - Heather Beasley, PhD - SLC25A46 as...
    Date: March 30, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join the Gibco Cell Culture Heroes webinar featuring Heather Beasley, PhD as she presents "SLC25A46 as a Novel Mitoc...
    Speaker: Heather Beasley, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    21
    MAR 22, 2023 | 6:00 AM
    Microfluidics Platforms for High Throughput In Vivo Screening
    Microfluidics Platforms for High Throughput In Vivo Screening
    Preclinical research and development are the cornerstone of modern drug discovery. A variety of biological systems including in vitro, 3D cultures, and organoids are essential tools, with ul...
    Speaker: Siva Vanapalli, PhD
    Presented at: Laboratory Automation Virtual Event Series 2023
    1
     
     
  • MAR 08, 2023 | 7:30 AM
    Keynote Presentation: Improving Research Translation in Dementia: Humanized Mouse Models, Cognition and Imaging with Live Q&A
    Keynote Presentation: Improving Research Translation in Dementia:...
    Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
    Speaker: Marco A.M. Prado, Pharm, MSc, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    4
    MAR 08, 2023 | 6:00 AM
    Novel Tools for Drug Discovery in Neurodegenerative Diseases
    Novel Tools for Drug Discovery in Neurodegenerative Diseases
    Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Both diseases are characterized by abnormal aggregates in the brain, which incl...
    Speaker: Jacob McPhail, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    3
    FEB 22, 2023 | 9:00 AM
    A scalable miniature circular GenCircleâ„¢ dsDNA production system for gene and cell therapy
    A scalable miniature circular GenCircleâ„¢ dsDNA production system...
    Date: February 22, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated...
    Speaker: Dr. Fan Zhou, PhD
    Sponsored By: GenScript
    7
    FEB 22, 2023 | 5:30 AM
    Cells, Tox and Rock 'n' Roll - Cell Validation and Drug-Induced Liver Injury Using a Human Liver Microphysiological System
    Cells, Tox and Rock 'n' Roll - Cell Validation and Drug-Induced...
    Ninety percent of therapeutic agents reaching clinical trial fail to reach entry to market, with safety concerns being a major cause for failures in phase I and II clinical trials. Drug-indu...
    Speaker: Christiana Skarlatopoulou
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
    FEB 22, 2023 | 5:30 AM
    Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
    Bridging the Gap - How Human Microphysiological Systems Improve...
    Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
    Speaker: Raul Silva
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
     
     
  • FEB 22, 2023 | 5:30 AM
    Avoiding InVivo Study Pitfalls
    Avoiding InVivo Study Pitfalls
    Learning Objectives: 1. Describe and discuss some of the unique aspect of in vivo studies. 2. Identify specific study practices to ensure high quality study data and animal welfare. 3. Discu...
    Speaker: Matthew Flegal, BS, SRS
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    1
    FEB 15, 2023 | 7:00 AM
    Scattering Microscopy: Label-Free Imaging Approaches
    Scattering Microscopy: Label-Free Imaging Approaches
    Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
    Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
    Sponsored By: Teledyne Photometrics
    28
    NOV 09, 2022 | 8:00 AM
    Addressing common challenges in lentiviral vector clarification using closed, automated counterflow centrifugation systems
    Addressing common challenges in lentiviral vector clarification...
    Date: November 09, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) The field of cell and gene therapy is rapidly growing. In particular, the use of lentiviruses in CAR-T applications is...
    Speaker: Carl Dargitz , Magda Tomala
    Sponsored By: Thermo Fisher Scientific, Sartorius
    16
    NOV 08, 2022 | 11:00 AM
    Thinking translational: Things to consider in CAR T cell workflows
    Thinking translational: Things to consider in CAR T cell workflows
    Date: November 08, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CET) Developing safe and effective CAR T cell therapies is a challenging task. That’s why thinking translational earl...
    Speaker: Robert Davies
    Sponsored By: Miltenyi Biotec
    9
    NOV 01, 2022 | 8:00 AM
    Debunking Antibody Titration Myths
    Debunking Antibody Titration Myths
    Date: November 01, 2022 Time: 8:00am (PDT), 1:00am (EDT), 4:00pm (CEST) This webinar will focus on sub-micron particle analysis utilizing high sensitivity violet side scatter detection. We w...
    Speaker: Diana Bonilla Escobar, PhD
    Sponsored By: Cytek Biosciences
    26
     
     
  • OCT 19, 2022 | 10:00 AM
    Immunodeficient Mouse Models to Support Prolonged Engraftment of Human NK and Tumor Cells
    Immunodeficient Mouse Models to Support Prolonged Engraftment...
    Date: October 19, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) In this webinar, we will introduce the generation and applications of Biocytogen’s severely immunodeficient (B-N...
    Speaker: Jenna Frame
    Sponsored By: Envigo
    13
    OCT 19, 2022 | 6:00 AM
    Evolution of SARS-CoV-2
    Evolution of SARS-CoV-2
    At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), emerged in China. As of September 2022, SARS-CoV...
    Speaker: Kei Sato, PhD
    Presented at: Coronavirus Series
    6
    SEP 29, 2022 | 6:00 AM
    Reliable Antifungal Susceptibility Testing with MICRONAUT-AM according to EUCAST standards
    Reliable Antifungal Susceptibility Testing with MICRONAUT-AM according...
    Date: September 29, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CET) The global burden of candidiasis remains relatively stable. However, the epidemiology of the last ten years shows a shi...
    Speaker: Alix Coste, PhD, FAMH
    Sponsored By: Bruker Microbiology & Diagnostics
    11
    SEP 15, 2022 | 9:00 AM
    Advances and Challenges in Targeting Kinases in Cancer Therapeutics
    Advances and Challenges in Targeting Kinases in Cancer Therapeutics
    Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
    Speaker: Aishath Shanaz Naeem , Veronique Baron
    Sponsored By: BPS Bioscience
    9
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