Laboratory Testing: Laboratory tests check a sample of your blood, urine, or body tissues. A technician or your doctor analyzes the test samples to see if your results fall within the normal range. The tests use a range because what is normal differs from person to person. Depending on the test, the presence, absence, or amount of an analyte may mean you do have a particular condition or it may mean that you do not have the particular condition.
In November of 2013 the AHA/ACA jointly proposed new guidelines for the management of hypercholesterolemia, the first full update in over a decade. The charge was to create evidence bas...
Liquid chromatography triple quadrupole mass spectrometry (LC/MS/MS) is ideally suited for the direct and rapid analysis of prepared biological samples. While analysis times can be shortened...
Until recently most of the phenotypic information on congenital endocrine disorders have relied on biochemical testing of steroids, biogenic amines and peptides but is now...
Aggressive low-density lipoprotein cholesterol (LDL-C) lowering strategies are recommended for prevention of cardiovascular events in high-risk populations. Guidelines recommend a 30-50% redu...
FDA has generally not enforced applicable regulatory requirements on a group of IVD tests called Laboratory Developed Tests. This use of “enforcement discretion” has been un...
There is agreement among clinicians that laboratory analyses are indispensable for correct diagnosis of disease, therapy, and patient monitoring. It is evident that laboratory data should be...
Drugs of abuse toxicology testing by immunoassays is widely used clinically, but also known to be inadequate for many clinical indications. In this presentation, the speaker will outline diff...
Cancer is complex, but recent findings are yielding a greater understanding of the disease. The tumor suppressor genes BRCA1 and BRCA2 are implicated in breast, ovarian, prostate, and other c...
Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
The process by which observations in the laboratory or the clinic are transformed into demonstrably useful interventions that tangibly improve human health is frequently termed "translation."...
The antibiotic pipeline is broken, with a dearth of new antibiotics, a collapse in pharmaceutical company research1, and the exhaustion of chemical diversity contained in pharma libraries. "T...
DATE: September 15, 2015TIME: 10:00AM Pacific time, 1:00PM Eastern timeThe breadth of instruments available for quantitative PCR (qPCR) has continued to grow in the past 5-10 years. With ...
Chromosomal microarray analysis (CMA) is an established technology, which has demonstrated great sensitivity and specificity for detecting genome-wide copy number variants (CNVs). CMA represe...
Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
Date: Thursday, June 25, 2015 Time: 10:00 AM PST, 12:00 PM CST, 1:00 PM ESTSerology testing continues to be an indispensable tool for the management of several disease states, especially tr...
Consistent accuracy in reporting quantitative viral load results is critically important to patients, their physicians and to the clinical laboratory. In clinical practice, quantitative viral...
Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Appropriate utilization of laboratory testing is important for the quality and safety in the healthcare system and to assist in the control of unnecessary costs in the healthcare system. Per...
When a patient presents with acute bloody diarrhea and tests negative for common causes such as campylobacter and salmonella, what's missing? Shiga toxin-producing E. coli (STEC) is increasin...
Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
With current NGS platforms, the boundaries of variant detection and gene content for genetic disease panels has been vastly expanded leading to increases in detection rates. However these pla...
The implementation of Next Generation Sequencing (NGS) technology in the clinical laboratory has allowed for large-scale panel testing of many genes simultaneously at a reduced cost and turn-...
In November of 2013 the AHA/ACA jointly proposed new guidelines for the management of hypercholesterolemia, the first full update in over a decade. The charge was to create evidence bas...
Liquid chromatography triple quadrupole mass spectrometry (LC/MS/MS) is ideally suited for the direct and rapid analysis of prepared biological samples. While analysis times can be shortened...
Until recently most of the phenotypic information on congenital endocrine disorders have relied on biochemical testing of steroids, biogenic amines and peptides but is now...
Aggressive low-density lipoprotein cholesterol (LDL-C) lowering strategies are recommended for prevention of cardiovascular events in high-risk populations. Guidelines recommend a 30-50% redu...
FDA has generally not enforced applicable regulatory requirements on a group of IVD tests called Laboratory Developed Tests. This use of “enforcement discretion” has been un...
There is agreement among clinicians that laboratory analyses are indispensable for correct diagnosis of disease, therapy, and patient monitoring. It is evident that laboratory data should be...
Drugs of abuse toxicology testing by immunoassays is widely used clinically, but also known to be inadequate for many clinical indications. In this presentation, the speaker will outline diff...
Cancer is complex, but recent findings are yielding a greater understanding of the disease. The tumor suppressor genes BRCA1 and BRCA2 are implicated in breast, ovarian, prostate, and other c...
Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
The process by which observations in the laboratory or the clinic are transformed into demonstrably useful interventions that tangibly improve human health is frequently termed "translation."...
The antibiotic pipeline is broken, with a dearth of new antibiotics, a collapse in pharmaceutical company research1, and the exhaustion of chemical diversity contained in pharma libraries. "T...
DATE: September 15, 2015TIME: 10:00AM Pacific time, 1:00PM Eastern timeThe breadth of instruments available for quantitative PCR (qPCR) has continued to grow in the past 5-10 years. With ...
Chromosomal microarray analysis (CMA) is an established technology, which has demonstrated great sensitivity and specificity for detecting genome-wide copy number variants (CNVs). CMA represe...
Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
Date: Thursday, June 25, 2015 Time: 10:00 AM PST, 12:00 PM CST, 1:00 PM ESTSerology testing continues to be an indispensable tool for the management of several disease states, especially tr...
Consistent accuracy in reporting quantitative viral load results is critically important to patients, their physicians and to the clinical laboratory. In clinical practice, quantitative viral...
Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
Appropriate utilization of laboratory testing is important for the quality and safety in the healthcare system and to assist in the control of unnecessary costs in the healthcare system. Per...
When a patient presents with acute bloody diarrhea and tests negative for common causes such as campylobacter and salmonella, what's missing? Shiga toxin-producing E. coli (STEC) is increasin...
Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
With current NGS platforms, the boundaries of variant detection and gene content for genetic disease panels has been vastly expanded leading to increases in detection rates. However these pla...
The implementation of Next Generation Sequencing (NGS) technology in the clinical laboratory has allowed for large-scale panel testing of many genes simultaneously at a reduced cost and turn-...
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