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    Mrna

    mRNA stands for messenger ribonucleic acids, is a type of RNA found in the cell. It transfers the information from DNA to the cell machinery that makes proteins. The mRNA is an RNA version of the gene that leaves the cell nucleus and moves to the cytoplasm where proteins are made.

    Webinars

    • OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      MAY 09, 2018 | 1:30 PM
      Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
      Next-Generation Sequencing to Understand the Function of miRNAs...
      There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
      Speaker: Ulrich Broeckel, MD , Amy Turner, BS
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      MAY 09, 2018 | 1:30 PM
      C.E. CREDITS
      Bimodal Gene Expression in Breast Cancer
      Bimodal Gene Expression in Breast Cancer
      Tumors are often categorized into standard molecular subtypes. However, largescale studies have demonstrated that patient heterogeneity in the regulatory make-up of tumors remain. At the tran...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      FEB 22, 2018 | 10:30 AM
      Protective Effect of a Novel Noncompetitive IL-1 Receptor-Biased Ligand in an Infection - and Inflammation-Induced Preterm Birth as Well as in Fetal Injury and Developmental Outcomes
      Protective Effect of a Novel Noncompetitive IL-1 Receptor-Biased...
      Preterm birth (PTB) is the leading cause of infant mortality and morbidity worldwide. Both preterm labor and neonatal injuries have been linked to inflammation. Of all mediators of inflammati...
      Speaker: Sylvain Chemtob, MD, PhD, FRCPC, FAAP, FCAHS
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      NOV 15, 2017 | 9:00 AM
      WEBINAR: The essential role of miRNA and mRNA on cancer progression and biomarker discovery
      WEBINAR: The essential role of miRNA and mRNA on cancer progression...
      DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
      Speaker: Dr. Malte Buchholz
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      6
      OCT 24, 2017 | 9:00 AM
      WEBINAR:  Genome Editing for Functional Genomics and Drug Discovery
      WEBINAR: Genome Editing for Functional Genomics and Drug Discovery
      DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
      Speaker: Chetana Revankar , Sanjay Kumar
      Sponsored By: Thermo Fisher Scientific
      4 2
      OCT 19, 2017 | 8:00 AM
      New viral and non-viral platforms for T-cell engineering
      New viral and non-viral platforms for T-cell engineering
      Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than ever for curative effects. However, many technical challenges in T c...
      Speaker: Xavier de Mollerat du Jeu
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      3
      OCT 19, 2017 | 8:00 AM
      WEBINAR: New viral and non-viral platforms for T-cell engineering
      WEBINAR: New viral and non-viral platforms for T-cell engineering
      DATE: October 19, 2017TIME: 08:00am PDT, 11:00am EDT Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than...
      Speaker: Xavier de Mollerat du Jeu
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      OCT 12, 2017 | 12:00 PM
      Comprehensive genomic and transcriptomic analysis of acral melanoma: A path towards therapeutic development
      Comprehensive genomic and transcriptomic analysis of acral melanoma:...
      Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
      Speaker: Winnie Liang, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      SEP 27, 2017 | 7:30 AM
      Keynote Presentation: What Microscopy Can Tell Us About the Life of an mRNA in Living Cells
      Keynote Presentation: What Microscopy Can Tell Us About the Life...
      Einstein researcher Robert Singer, Ph.D., discusses a breakthrough in microscopy that is allowing scientists to track messenger RNA in living cells in real time. The study, published in the S...
      Speaker: Robert Singer, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      JUL 01, 2017 | 12:00 AM
      Highly efficient stem cell engineering via Cas9 protein transfection
      Highly efficient stem cell engineering via Cas9 protein transfection
      CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering.  The delivery of Cas9 plasmid DNA or mR...
      Speaker: Xiquan Liang
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUN 28, 2017 | 9:00 AM
      WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution RNA maps for the regulation of alternative polyadenylation
      WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution...
      DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
      Speaker: Jernej Ule, PhD , Gregor Rot, PhD
      Sponsored By: Lexogen
      5
      MAY 10, 2017 | 1:30 PM
      Addressing "NGS Dead Zones" with Third-Generation PacBio Sequencing
      Addressing "NGS Dead Zones" with Third-Generation PacBio Sequencing
      SMRT Sequencing is a DNA sequencing technology characterized by long read lengths and high consensus accuracy, regardless of the sequence complexity or GC content of the DNA sample. These cha...
      Speaker: Jonas Korlach, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2017
      Sponsored By: PacBio
      2
      MAY 10, 2017 | 12:00 PM
      Identifying genes "related to" or "specific for" a disease of interest
      Identifying genes "related to" or "specific for" a disease of...
      A plethora of methods and tools have been developed to identify genes differentially expressed between two compared conditions, such as "diseased versus healthy". For many scientist...
      Speaker: Philip Zimmerman, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2017
      2
      APR 05, 2017 | 6:00 AM
      A workflow for CRISPR-Cas9 high throughput arrayed screening with synthetic crRNA
      A workflow for CRISPR-Cas9 high throughput arrayed screening with...
      There is rapidly growing interest in using the CRISPR-Cas9 system for functional screening, both as a primary screening tool and as an orthogonal tool for RNAi hit validation. High throughput...
      Speaker: Louise Baskin
      Presented at: Protein Research Live
      20
      MAR 21, 2017 | 10:00 AM
      WEBINAR: Application of combined RNA in situ hybridization and multiplex immunohistochemistry to unravel tumor heterogeneity in prostate cancer
      WEBINAR: Application of combined RNA in situ hybridization and...
      DATE: March 21, 2017TIME: 10:00am PT, 1:00pm ETSponsored By:      Prostate cancer is a complex disease with multiple tumors originating independent...
      Speaker: Nallasivam Palanisamy, PhD , Courtney Anderson, PhD
      Sponsored By: Novus Biologicals a Bio-Techne Brand
      20 9
      FEB 20, 2017 | 8:00 AM
      Getting started with siRNA: considerations and recommendations
      Getting started with siRNA: considerations and recommendations
      This is an introduction to the biological mechanism of RNA interference (RNAi) and experimental application of short, interfering RNA (siRNA). The key steps of the endogenous RNAi pathway wil...
      Speaker: Louise Baskin
      Presented at: Protein Research Live
      3
      DEC 14, 2016 | 9:00 AM
      Beyond Sequencing: Population Analysis in an Era of Mass Spectrometry Proteomics
      Beyond Sequencing: Population Analysis in an Era of Mass Spectrometry...
      DATE: December 14, 2016TIME: 9:00 AM PT, 12:00 PM ETMicroarrays and nucleotide sequencers have become commonplace tools in current research, yet until now, equivalent technologies for p...
      Speaker: Evan Williams, PhD
      Sponsored By: SCIEX, SCIEX
      25
      NOV 17, 2016 | 8:30 AM
      Simultaneous, single-cell visualization of RNA and Protein
      Simultaneous, single-cell visualization of RNA and Protein
      DATE: November 17, 2016 TIME: 8:30am PT, 11:30am ET The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
      Speaker: Sara Becker-Catania, PhD
      Sponsored By: eBioscience Business Unit, Thermo Fisher Scientific, eBioscience Business Unit, Thermo Fisher Scientific
      4
      NOV 16, 2016 | 8:00 AM
      The important role of lncRNAs in breast cancer
      The important role of lncRNAs in breast cancer
      DATE:  November 16, 2016 TIME:  8:00am PT, 11:00am ET  Breast cancer is the most commonly diagnosed cancer in women and is the second leading cause of cancer death among wo...
      Speaker: Rebecca DeVaux, PhD , Alfredo Hidalgo-Miranda, PhD
      Sponsored By: Affymetrix, Affymetrix
      8
      NOV 10, 2016 | 10:00 AM
      How Do You effectively Detect Heterogeneity in Single-cells?
      How Do You effectively Detect Heterogeneity in Single-cells?
      Bulk analysis often leads to conclusions that assume averages reflect the dominant biological mechanism operating within an entire population. To fully understand how cellular heterogeneity c...
      Speaker:
      Presented at: Microbiology Virtual Event Series 2015
      0
      NOV 10, 2016 | 10:00 AM
      Single-cell analysis of virus infection:  Zika & beyond
      Single-cell analysis of virus infection: Zika & beyond
      DATE:  November 10, 2016 TIME:  10am PT, 1pm ET How do you effectively detect heterogeneity in single cells? Bulk analysis often leads to conclusions that assume average...
      Speaker: Eric Clambey, PhD
      Sponsored By: Affymetrix, Affymetrix
      6
      OCT 19, 2016 | 9:00 AM
      Controlling RNA-Seq Experiments Using Spike-In RNA Variants
      Controlling RNA-Seq Experiments Using Spike-In RNA Variants
      DATE: October 19, 2016 TIME:  9:00 AM PT, 12:00 PM ET, 6:00 PM CEST    Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
      Speaker: Lukas Paul, PhD
      Sponsored By: Lexogen, Lexogen
      7 2
      OCT 04, 2016 | 8:00 AM
      Overcoming the Clinical Sample Bottleneck for Expression Studies
      Overcoming the Clinical Sample Bottleneck for Expression Studies
      DATE:  October 4, 2016 TIME:  8:00am PT, 11:00am ET Extracting robust expression data from clinical samples represents a unique opportunity to find actionable biomarkers. But it...
      Speaker: Mark Manary, MD , Sean Diehl, PhD
      Sponsored By: Affymetrix, Affymetrix
      4
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    MAY 09, 2018 | 1:30 PM
    Next-Generation Sequencing to Understand the Function of miRNAs in Human IPSC-Cardiomyocyte Disease Models
    Next-Generation Sequencing to Understand the Function of miRNAs...
    There is increasing evidence that intracellular miRNAs play a role in the pathogenesis of many complex disease phenotypes.  In addition, extracellular miRNAs in exosomes are emerging as...
    Speaker: Ulrich Broeckel, MD , Amy Turner, BS
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    MAY 09, 2018 | 1:30 PM
    C.E. CREDITS
    Bimodal Gene Expression in Breast Cancer
    Bimodal Gene Expression in Breast Cancer
    Tumors are often categorized into standard molecular subtypes. However, largescale studies have demonstrated that patient heterogeneity in the regulatory make-up of tumors remain. At the tran...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    FEB 22, 2018 | 10:30 AM
    Protective Effect of a Novel Noncompetitive IL-1 Receptor-Biased Ligand in an Infection - and Inflammation-Induced Preterm Birth as Well as in Fetal Injury and Developmental Outcomes
    Protective Effect of a Novel Noncompetitive IL-1 Receptor-Biased...
    Preterm birth (PTB) is the leading cause of infant mortality and morbidity worldwide. Both preterm labor and neonatal injuries have been linked to inflammation. Of all mediators of inflammati...
    Speaker: Sylvain Chemtob, MD, PhD, FRCPC, FAAP, FCAHS
    Presented at: Drug Discovery Virtual Event Series 2018
    1
    NOV 15, 2017 | 9:00 AM
    WEBINAR: The essential role of miRNA and mRNA on cancer progression and biomarker discovery
    WEBINAR: The essential role of miRNA and mRNA on cancer progression...
    DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
    Speaker: Dr. Malte Buchholz
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    6
     
     
  • OCT 24, 2017 | 9:00 AM
    WEBINAR:  Genome Editing for Functional Genomics and Drug Discovery
    WEBINAR: Genome Editing for Functional Genomics and Drug Discovery
    DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
    Speaker: Chetana Revankar , Sanjay Kumar
    Sponsored By: Thermo Fisher Scientific
    4 2
    OCT 19, 2017 | 8:00 AM
    New viral and non-viral platforms for T-cell engineering
    New viral and non-viral platforms for T-cell engineering
    Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than ever for curative effects. However, many technical challenges in T c...
    Speaker: Xavier de Mollerat du Jeu
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    3
    OCT 19, 2017 | 8:00 AM
    WEBINAR: New viral and non-viral platforms for T-cell engineering
    WEBINAR: New viral and non-viral platforms for T-cell engineering
    DATE: October 19, 2017TIME: 08:00am PDT, 11:00am EDT Recent FDA approval of the first Chimeric Antigen Receptor T cell (CAR-T) therapy offers cancer patients more promise than...
    Speaker: Xavier de Mollerat du Jeu
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    OCT 12, 2017 | 12:00 PM
    Comprehensive genomic and transcriptomic analysis of acral melanoma: A path towards therapeutic development
    Comprehensive genomic and transcriptomic analysis of acral melanoma:...
    Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
    Speaker: Winnie Liang, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    SEP 27, 2017 | 7:30 AM
    Keynote Presentation: What Microscopy Can Tell Us About the Life of an mRNA in Living Cells
    Keynote Presentation: What Microscopy Can Tell Us About the Life...
    Einstein researcher Robert Singer, Ph.D., discusses a breakthrough in microscopy that is allowing scientists to track messenger RNA in living cells in real time. The study, published in the S...
    Speaker: Robert Singer, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
     
     
  • JUL 01, 2017 | 12:00 AM
    Highly efficient stem cell engineering via Cas9 protein transfection
    Highly efficient stem cell engineering via Cas9 protein transfection
    CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering.  The delivery of Cas9 plasmid DNA or mR...
    Speaker: Xiquan Liang
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUN 28, 2017 | 9:00 AM
    WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution RNA maps for the regulation of alternative polyadenylation
    WEBINAR: Integration of 3´ mRNA-Seq and iCLIP to derive high-resolution...
    DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
    Speaker: Jernej Ule, PhD , Gregor Rot, PhD
    Sponsored By: Lexogen
    5
    MAY 10, 2017 | 1:30 PM
    Addressing "NGS Dead Zones" with Third-Generation PacBio Sequencing
    Addressing "NGS Dead Zones" with Third-Generation PacBio Sequencing
    SMRT Sequencing is a DNA sequencing technology characterized by long read lengths and high consensus accuracy, regardless of the sequence complexity or GC content of the DNA sample. These cha...
    Speaker: Jonas Korlach, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2017
    Sponsored By: PacBio
    2
    MAY 10, 2017 | 12:00 PM
    Identifying genes "related to" or "specific for" a disease of interest
    Identifying genes "related to" or "specific for" a disease of...
    A plethora of methods and tools have been developed to identify genes differentially expressed between two compared conditions, such as "diseased versus healthy". For many scientist...
    Speaker: Philip Zimmerman, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2017
    2
    APR 05, 2017 | 6:00 AM
    A workflow for CRISPR-Cas9 high throughput arrayed screening with synthetic crRNA
    A workflow for CRISPR-Cas9 high throughput arrayed screening with...
    There is rapidly growing interest in using the CRISPR-Cas9 system for functional screening, both as a primary screening tool and as an orthogonal tool for RNAi hit validation. High throughput...
    Speaker: Louise Baskin
    Presented at: Protein Research Live
    20
     
     
  • MAR 21, 2017 | 10:00 AM
    WEBINAR: Application of combined RNA in situ hybridization and multiplex immunohistochemistry to unravel tumor heterogeneity in prostate cancer
    WEBINAR: Application of combined RNA in situ hybridization and...
    DATE: March 21, 2017TIME: 10:00am PT, 1:00pm ETSponsored By:      Prostate cancer is a complex disease with multiple tumors originating independent...
    Speaker: Nallasivam Palanisamy, PhD , Courtney Anderson, PhD
    Sponsored By: Novus Biologicals a Bio-Techne Brand
    20 9
    FEB 20, 2017 | 8:00 AM
    Getting started with siRNA: considerations and recommendations
    Getting started with siRNA: considerations and recommendations
    This is an introduction to the biological mechanism of RNA interference (RNAi) and experimental application of short, interfering RNA (siRNA). The key steps of the endogenous RNAi pathway wil...
    Speaker: Louise Baskin
    Presented at: Protein Research Live
    3
    DEC 14, 2016 | 9:00 AM
    Beyond Sequencing: Population Analysis in an Era of Mass Spectrometry Proteomics
    Beyond Sequencing: Population Analysis in an Era of Mass Spectrometry...
    DATE: December 14, 2016TIME: 9:00 AM PT, 12:00 PM ETMicroarrays and nucleotide sequencers have become commonplace tools in current research, yet until now, equivalent technologies for p...
    Speaker: Evan Williams, PhD
    Sponsored By: SCIEX, SCIEX
    25
    NOV 17, 2016 | 8:30 AM
    Simultaneous, single-cell visualization of RNA and Protein
    Simultaneous, single-cell visualization of RNA and Protein
    DATE: November 17, 2016 TIME: 8:30am PT, 11:30am ET The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
    Speaker: Sara Becker-Catania, PhD
    Sponsored By: eBioscience Business Unit, Thermo Fisher Scientific, eBioscience Business Unit, Thermo Fisher Scientific
    4
    NOV 16, 2016 | 8:00 AM
    The important role of lncRNAs in breast cancer
    The important role of lncRNAs in breast cancer
    DATE:  November 16, 2016 TIME:  8:00am PT, 11:00am ET  Breast cancer is the most commonly diagnosed cancer in women and is the second leading cause of cancer death among wo...
    Speaker: Rebecca DeVaux, PhD , Alfredo Hidalgo-Miranda, PhD
    Sponsored By: Affymetrix, Affymetrix
    8
     
     
  • NOV 10, 2016 | 10:00 AM
    How Do You effectively Detect Heterogeneity in Single-cells?
    How Do You effectively Detect Heterogeneity in Single-cells?
    Bulk analysis often leads to conclusions that assume averages reflect the dominant biological mechanism operating within an entire population. To fully understand how cellular heterogeneity c...
    Speaker:
    Presented at: Microbiology Virtual Event Series 2015
    0
    NOV 10, 2016 | 10:00 AM
    Single-cell analysis of virus infection:  Zika & beyond
    Single-cell analysis of virus infection: Zika & beyond
    DATE:  November 10, 2016 TIME:  10am PT, 1pm ET How do you effectively detect heterogeneity in single cells? Bulk analysis often leads to conclusions that assume average...
    Speaker: Eric Clambey, PhD
    Sponsored By: Affymetrix, Affymetrix
    6
    OCT 19, 2016 | 9:00 AM
    Controlling RNA-Seq Experiments Using Spike-In RNA Variants
    Controlling RNA-Seq Experiments Using Spike-In RNA Variants
    DATE: October 19, 2016 TIME:  9:00 AM PT, 12:00 PM ET, 6:00 PM CEST    Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
    Speaker: Lukas Paul, PhD
    Sponsored By: Lexogen, Lexogen
    7 2
    OCT 04, 2016 | 8:00 AM
    Overcoming the Clinical Sample Bottleneck for Expression Studies
    Overcoming the Clinical Sample Bottleneck for Expression Studies
    DATE:  October 4, 2016 TIME:  8:00am PT, 11:00am ET Extracting robust expression data from clinical samples represents a unique opportunity to find actionable biomarkers. But it...
    Speaker: Mark Manary, MD , Sean Diehl, PhD
    Sponsored By: Affymetrix, Affymetrix
    4
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