A primary cell is a battery that is designed to be used once and discarded, and not recharged with electricity and reused like a secondary cell. In general, the electrochemical reaction occurring in the cell is not reversible, rendering the cell unrechargeable.
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Cell painting has established itself as a powerful tool for high content imaging, able to generate vast quantities of data in response to chemical perturbations. Over the past decade, cell p...
Real-time reverse transcription PCR analysis of RNA expression in normal and diseased states is a fundamental technique used in research workflows. Immortalized and primary cells are often u...
Deciphering somatic mosaicism in healthy tissues and clonal diversity in tumors necessitates single-cell analysis. High-quality genomic and transcriptomic data at the single-cell level depen...
Learning Objevtives: 1. Demonstrate Knowledge with gene editing, microfluidics and non-viral delivery methods. 2. Review the uses of a low-volume high-throughput transfection platform for ge...
NAFLD (non-alcoholic fatty liver disease) is a global epidemic that affects 25% of the world’s population, with its epicentre in the West. Twenty percent of NAFLD patients go on to dev...
Learning Objectives: 1. Summarize the benefits and challenges of current preclinical methods in drug discovery and development. 2. Review new alternative methodologies (NAMs) and microphysio...
Calcium signaling is essential for cellular communication, orchestrating a myriad of physiological processes. As the quest for a more profound understanding of cellular dynamics intensifies,...
Spheroids and organoids, two examples of 3D cell culture models, have become invaluable tools to study the processes that dictate behavior of tissues under physiological and pathological con...
With the fast progress and deeper understanding of CAR-T cell therapy, finding a better solution other than lentivirus transduction is more requested, to overcome the functional limitation o...