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    Research

    Research: comprises "creative and systematic work undertaken to increase the stock of knowledge, including knowledge of humans, culture and society, and the use of this stock of knowledge to devise new applications."

    Webinars

    • SEP 24, 2014 | 7:00 AM
      Making molecular prosthetics
      Making molecular prosthetics
      Diseases caused by an excess of protein function can often be treated by small molecule inhibitors. In contrast, many diseases caused by missing proteins cannot be addressed with this classic...
      Speaker: Martin Burke , MD, PhD
      Presented at: Advances in Drug Discovery and Development
      30
      SEP 24, 2014 | 6:00 AM
      Attacking Dementias Moving from symptoms to causes the advance of precision medicine
      Attacking Dementias Moving from symptoms to causes the advance...
      Transforming serious brain disease through cutting edge science, generating novel medicines that enable patients to overcome everyday challenges and achieve their full potential...
      Speaker: Deborah Dunsire, MD
      Presented at: Advances in Drug Discovery and Development
      58
      SEP 24, 2014 | 6:00 AM
      Translational Medicine for Rare Disease: Lessons from Duchenne Muscular Dystrophy
      Translational Medicine for Rare Disease: Lessons from Duchenne...
      Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disease occurring in 1 in 3,500 births, and is uniformly fatal in boys. It is caused by any one of over 50 known mutations in the gen...
      Speaker: Susan Ward, PhD
      Presented at: Advances in Drug Discovery and Development
      14
      SEP 24, 2014 | 5:00 AM
      Exploring macrocycles for drug discovery: Novel lead series for challenging protein-protein interactions
      Exploring macrocycles for drug discovery: Novel lead series for...
      Macrocycles offer a new structural class that has the potential to address challenging protein-protein interaction targets and still present attractive drug-like properties including cell mem...
      Speaker: Nick K. Terrett, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      16
      SEP 24, 2014 | 5:00 AM
      Algorithmic Drug Design (Prerecorded)
      Algorithmic Drug Design (Prerecorded)
      Since leaving Pfizer to go back to academia in 2007, Andrew Hopkins (University of Dundee, UK) has been a leading researcher in the search for new informatics and computational methods to imp...
      Speaker: Andrew Hopkins, FRSC
      Presented at: Advances in Drug Discovery and Development
      28
      SEP 16, 2014 | 10:00 AM
      Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
      Expanded clinical research opportunities for Crizotinib identified...
      Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
      Speaker: Sean Eddy, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      12
      SEP 16, 2014 | 9:30 AM
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
      Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
      Speaker: Nickolay Khazanov, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      18
      SEP 16, 2014 | 8:30 AM
      The use of transcriptional signatures for clinical population selection
      The use of transcriptional signatures for clinical population...
      The use of biomarkers for the stratification of populations for therapy is a concept that holds the potential to revolutionize clinical trial design, the economics of healthcare, and most imp...
      Speaker: Mary Ellen Urick, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      18
      SEP 16, 2014 | 8:00 AM
      Overview
      Overview
      ...
      Speaker: Emma Bowden, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      6
      SEP 11, 2014 | 9:00 AM
      The Clinical Utility of 1,25 Dihydroxyvitamin D
      The Clinical Utility of 1,25 Dihydroxyvitamin D
        Practicing Internist and vitamin D researcher Gregory A. Plotnikoff, MD, MTS, FACP, will review how new testing for 1,25-Dihydroxyvitamin D can enhance your clinical practice. Issues to be ...
      Speaker: Gregory Plotnikoff, MD, MTS, FACP
      Sponsored By: Diasorin, Diasorin
      51
      SEP 10, 2014 | 10:00 AM
      NGS Lessons in Translational Diagnostics
      NGS Lessons in Translational Diagnostics
      In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
      Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
      Sponsored By: Asuragen, Asuragen
      48
      SEP 10, 2014 | 7:00 AM
      Physical & Chemical Characterization of Nanoparticle Constructs using the Analytical Ultracentrifuge
      Physical & Chemical Characterization of Nanoparticle Constructs...
        Colloidal nanoparticles have become important materials in biomedicine, catalysis, and optoelectronics. Their unique nanoscale properties stem from their size (particularly of the i...
      Speaker: Osman M Bakr, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      25
      AUG 21, 2014 | 3:00 PM
      Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
      Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
      ...
      Speaker: Piero Carninci, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      0
      AUG 21, 2014 | 2:30 PM
      Integrating patient specific information in rare disorder analysis
      Integrating patient specific information in rare disorder analysis
      Rare disorder analysis has been facilitated by the declining cost of sequencing. Despite numerous success stories the underlying cause remains unexplained in >50% cases, emphasizing the ne...
      Speaker: Asif Javed, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      28
      AUG 21, 2014 | 12:45 PM
      Predictive and not: understanding the mixed messages of our DNA
      Predictive and not: understanding the mixed messages of our DNA
      When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
      Speaker: Cecile Janssens, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      36
      AUG 21, 2014 | 12:15 PM
      A Next-Gen Sequencing Software Workflow for Gene Panel Validation Control
      A Next-Gen Sequencing Software Workflow for Gene Panel Validation...
      DNASTAR offers an integrated suite of software for assembling and analyzing sequence data from all major next-generation sequencing platforms. DNASTAR software supports a variety of key workf...
      Speaker: Matthew Keyser, MS
      Presented at: Genetics and Genomics Virtual Event Series 2014
      11
      AUG 21, 2014 | 11:30 AM
      Understanding the Genetics of Common Disease:  Using Big Data approaches to see the emergent whole
      Understanding the Genetics of Common Disease: Using Big Data...
      The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2014
      198
      AUG 21, 2014 | 11:15 AM
      Keynote: Integration of Genetics and Genomics into Medical Practice: Educational Challenges
      Keynote: Integration of Genetics and Genomics into Medical Practice:...
      Medical applications of genetics and genomics have been advancing dramatically since completion of the sequencing of the human genome. The cost of DNA sequencing has plummeted, leading to the...
      Speaker: Bruce R. Korf, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      76
      AUG 21, 2014 | 10:45 AM
      The Role of Genetic Counselors in the Implementation of Personalized Genomic Medicine
      The Role of Genetic Counselors in the Implementation of Personalized...
      For personalized genomic medicine (PGM) to be readily adopted into clinical practice, there is a need for a multidisciplinary team, and a need to educate health care professionals and the...
      Speaker: Colleen Campbell, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      128
      AUG 21, 2014 | 9:45 AM
      Shotgun sequencing enables non-invasive monitoring of infection and rejection in transplantation
      Shotgun sequencing enables non-invasive monitoring of infection...
      Accurate and timely diagnosis of rejection and infection is essential for long-term survival of solid-organ transplant recipients. We evaluated the performance a novel test to monitor rejecti...
      Speaker: Iwijn De Vlaminck, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      64
      AUG 21, 2014 | 9:45 AM
      Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
      Pathway based analyses for genetic susceptibility to cancer and...
      In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      62
      AUG 21, 2014 | 9:30 AM
      Studying the Transcriptome with Next-Generation Sequencing
      Studying the Transcriptome with Next-Generation Sequencing
      Next-Generation Sequencing is enabling scientists to study the transcriptome in ways never before possible. During this session with Illumina Distinguished Scientist, Dr. Gary Schroth, you w...
      Speaker: Gary Schroth,PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      68
      AUG 21, 2014 | 8:45 AM
      Genome and exome sequencing in a clinical laboratory
      Genome and exome sequencing in a clinical laboratory
      With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
      Speaker: Matthew Lebo, PhD, FACMG
      Presented at: Genetics and Genomics Virtual Event Series 2014
      30
      AUG 21, 2014 | 8:45 AM
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
      Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
      Speaker: Luk H Vandenberghe, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      0
    SEP 24, 2014 | 7:00 AM
    Making molecular prosthetics
    Making molecular prosthetics
    Diseases caused by an excess of protein function can often be treated by small molecule inhibitors. In contrast, many diseases caused by missing proteins cannot be addressed with this classic...
    Speaker: Martin Burke , MD, PhD
    Presented at: Advances in Drug Discovery and Development
    30
    SEP 24, 2014 | 6:00 AM
    Attacking Dementias Moving from symptoms to causes the advance of precision medicine
    Attacking Dementias Moving from symptoms to causes the advance...
    Transforming serious brain disease through cutting edge science, generating novel medicines that enable patients to overcome everyday challenges and achieve their full potential...
    Speaker: Deborah Dunsire, MD
    Presented at: Advances in Drug Discovery and Development
    58
    SEP 24, 2014 | 6:00 AM
    Translational Medicine for Rare Disease: Lessons from Duchenne Muscular Dystrophy
    Translational Medicine for Rare Disease: Lessons from Duchenne...
    Duchenne Muscular Dystrophy (DMD) is an X-linked genetic disease occurring in 1 in 3,500 births, and is uniformly fatal in boys. It is caused by any one of over 50 known mutations in the gen...
    Speaker: Susan Ward, PhD
    Presented at: Advances in Drug Discovery and Development
    14
    SEP 24, 2014 | 5:00 AM
    Exploring macrocycles for drug discovery: Novel lead series for challenging protein-protein interactions
    Exploring macrocycles for drug discovery: Novel lead series for...
    Macrocycles offer a new structural class that has the potential to address challenging protein-protein interaction targets and still present attractive drug-like properties including cell mem...
    Speaker: Nick K. Terrett, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    16
    SEP 24, 2014 | 5:00 AM
    Algorithmic Drug Design (Prerecorded)
    Algorithmic Drug Design (Prerecorded)
    Since leaving Pfizer to go back to academia in 2007, Andrew Hopkins (University of Dundee, UK) has been a leading researcher in the search for new informatics and computational methods to imp...
    Speaker: Andrew Hopkins, FRSC
    Presented at: Advances in Drug Discovery and Development
    28
     
     
  • SEP 16, 2014 | 10:00 AM
    Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
    Expanded clinical research opportunities for Crizotinib identified...
    Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
    Speaker: Sean Eddy, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    12
    SEP 16, 2014 | 9:30 AM
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
    Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
    Speaker: Nickolay Khazanov, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    18
    SEP 16, 2014 | 8:30 AM
    The use of transcriptional signatures for clinical population selection
    The use of transcriptional signatures for clinical population...
    The use of biomarkers for the stratification of populations for therapy is a concept that holds the potential to revolutionize clinical trial design, the economics of healthcare, and most imp...
    Speaker: Mary Ellen Urick, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    18
    SEP 16, 2014 | 8:00 AM
    Overview
    Overview
    ...
    Speaker: Emma Bowden, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    6
    SEP 11, 2014 | 9:00 AM
    The Clinical Utility of 1,25 Dihydroxyvitamin D
    The Clinical Utility of 1,25 Dihydroxyvitamin D
      Practicing Internist and vitamin D researcher Gregory A. Plotnikoff, MD, MTS, FACP, will review how new testing for 1,25-Dihydroxyvitamin D can enhance your clinical practice. Issues to be ...
    Speaker: Gregory Plotnikoff, MD, MTS, FACP
    Sponsored By: Diasorin, Diasorin
    51
     
     
  • SEP 10, 2014 | 10:00 AM
    NGS Lessons in Translational Diagnostics
    NGS Lessons in Translational Diagnostics
    In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
    Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
    Sponsored By: Asuragen, Asuragen
    48
    SEP 10, 2014 | 7:00 AM
    Physical & Chemical Characterization of Nanoparticle Constructs using the Analytical Ultracentrifuge
    Physical & Chemical Characterization of Nanoparticle Constructs...
      Colloidal nanoparticles have become important materials in biomedicine, catalysis, and optoelectronics. Their unique nanoscale properties stem from their size (particularly of the i...
    Speaker: Osman M Bakr, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    25
    AUG 21, 2014 | 3:00 PM
    Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
    Unexpected Findings from Analysis of Complex Mammalian Transcriptomes
    ...
    Speaker: Piero Carninci, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    0
    AUG 21, 2014 | 2:30 PM
    Integrating patient specific information in rare disorder analysis
    Integrating patient specific information in rare disorder analysis
    Rare disorder analysis has been facilitated by the declining cost of sequencing. Despite numerous success stories the underlying cause remains unexplained in >50% cases, emphasizing the ne...
    Speaker: Asif Javed, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    28
    AUG 21, 2014 | 12:45 PM
    Predictive and not: understanding the mixed messages of our DNA
    Predictive and not: understanding the mixed messages of our DNA
    When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
    Speaker: Cecile Janssens, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    36
     
     
  • AUG 21, 2014 | 12:15 PM
    A Next-Gen Sequencing Software Workflow for Gene Panel Validation Control
    A Next-Gen Sequencing Software Workflow for Gene Panel Validation...
    DNASTAR offers an integrated suite of software for assembling and analyzing sequence data from all major next-generation sequencing platforms. DNASTAR software supports a variety of key workf...
    Speaker: Matthew Keyser, MS
    Presented at: Genetics and Genomics Virtual Event Series 2014
    11
    AUG 21, 2014 | 11:30 AM
    Understanding the Genetics of Common Disease:  Using Big Data approaches to see the emergent whole
    Understanding the Genetics of Common Disease: Using Big Data...
    The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2014
    198
    AUG 21, 2014 | 11:15 AM
    Keynote: Integration of Genetics and Genomics into Medical Practice: Educational Challenges
    Keynote: Integration of Genetics and Genomics into Medical Practice:...
    Medical applications of genetics and genomics have been advancing dramatically since completion of the sequencing of the human genome. The cost of DNA sequencing has plummeted, leading to the...
    Speaker: Bruce R. Korf, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    76
    AUG 21, 2014 | 10:45 AM
    The Role of Genetic Counselors in the Implementation of Personalized Genomic Medicine
    The Role of Genetic Counselors in the Implementation of Personalized...
    For personalized genomic medicine (PGM) to be readily adopted into clinical practice, there is a need for a multidisciplinary team, and a need to educate health care professionals and the...
    Speaker: Colleen Campbell, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    128
    AUG 21, 2014 | 9:45 AM
    Shotgun sequencing enables non-invasive monitoring of infection and rejection in transplantation
    Shotgun sequencing enables non-invasive monitoring of infection...
    Accurate and timely diagnosis of rejection and infection is essential for long-term survival of solid-organ transplant recipients. We evaluated the performance a novel test to monitor rejecti...
    Speaker: Iwijn De Vlaminck, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    64
     
     
  • AUG 21, 2014 | 9:45 AM
    Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
    Pathway based analyses for genetic susceptibility to cancer and...
    In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    62
    AUG 21, 2014 | 9:30 AM
    Studying the Transcriptome with Next-Generation Sequencing
    Studying the Transcriptome with Next-Generation Sequencing
    Next-Generation Sequencing is enabling scientists to study the transcriptome in ways never before possible. During this session with Illumina Distinguished Scientist, Dr. Gary Schroth, you w...
    Speaker: Gary Schroth,PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    68
    AUG 21, 2014 | 8:45 AM
    Genome and exome sequencing in a clinical laboratory
    Genome and exome sequencing in a clinical laboratory
    With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
    Speaker: Matthew Lebo, PhD, FACMG
    Presented at: Genetics and Genomics Virtual Event Series 2014
    30
    AUG 21, 2014 | 8:45 AM
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
    Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
    Speaker: Luk H Vandenberghe, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    0
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