The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) is a research initiative that is a collaboration of public and private research established by the Obama Administration in 2013. The purpose of the initiative is to aid in the application and creation of technology to better understand the function of the brain. Researchers under BRAIN strive to further explore the causes of brain disorders such as: Alzheimer's, Parkinson's, depression, and traumatic brain injury.
Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The BRAIN Initiative is enabling exciting advances in our understanding of human neuroscience. This session will highlight recent advances made towards understanding the human nervous system...
The goal is to inform the community of the BRAIN Initiative's support for the diversity of species used in neuroscience research. By leveraging advances in genetics and neuroscience tool...
Novel neurotechnologies are generating exciting opportunities for groups in The BRAIN Initiative and the broader biomedical community to re-imagine the boundaries of recording and modulating...
The BRAIN Initiative has enabled the development of novel neural recording tools that can benefit many labs, but are difficult to transition to industry for a variety of reasons. Here we ass...
Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
Brain machine interfaces (BMIs) aim to help patients with paralysis to use their recorded brain activity to control assistive devices. BMI research requires the collaboration of neuroscienti...
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
Brain function is remarkably reliable despite the imprecise performance of neurons, and the continuous perturbations caused by aging, disease or injury. How does the brain succeed in produci...
The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
I describe a framework for improving the targeting and precision of transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique used for research and clinical applicat...
Early phase clinical trials investigating novel applications of neural devices, such as deep brain stimulation (DBS) devices, pose ethical challenge during the recruitment of human subjects...
Recent technological advancements in neuroprosthetics allow for wireless recording and stimulation of brain activity in freely moving human participants. At the same time, advancements in vi...
Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The BRAIN Initiative is enabling exciting advances in our understanding of human neuroscience. This session will highlight recent advances made towards understanding the human nervous system...
The goal is to inform the community of the BRAIN Initiative's support for the diversity of species used in neuroscience research. By leveraging advances in genetics and neuroscience tool...
Novel neurotechnologies are generating exciting opportunities for groups in The BRAIN Initiative and the broader biomedical community to re-imagine the boundaries of recording and modulating...
The BRAIN Initiative has enabled the development of novel neural recording tools that can benefit many labs, but are difficult to transition to industry for a variety of reasons. Here we ass...
Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
Brain machine interfaces (BMIs) aim to help patients with paralysis to use their recorded brain activity to control assistive devices. BMI research requires the collaboration of neuroscienti...
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
Brain function is remarkably reliable despite the imprecise performance of neurons, and the continuous perturbations caused by aging, disease or injury. How does the brain succeed in produci...
The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
I describe a framework for improving the targeting and precision of transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique used for research and clinical applicat...
Early phase clinical trials investigating novel applications of neural devices, such as deep brain stimulation (DBS) devices, pose ethical challenge during the recruitment of human subjects...
Recent technological advancements in neuroprosthetics allow for wireless recording and stimulation of brain activity in freely moving human participants. At the same time, advancements in vi...
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