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    Cancer Biology

    Cancer biology can be defined as the sub-field of biology targeted towards understanding Cancer, usually at the cellular level. While targeted towards cancer, it involves the research of everything from the adverse cellular processes of a cancer cell, to the hosts immune response, as well as every avenue in order to abolish the disease.

    Webinars

    • FEB 10, 2015 | 12:00 PM
      Primary HPV Cervical Cancer Screening: Supporting data and guidance updates
      Primary HPV Cervical Cancer Screening: Supporting data and guidance...
      Date: Tuesday, February 10th, 2015Time: 12:00PM PST, 3:00PM ESTFor the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology ...
      Speaker: Julia Engstrom-Melnyk, PhD
      Sponsored By: Roche Molecular Diagnostics, Roche Molecular Diagnostics
      8 5
      FEB 10, 2015 | 9:00 AM
      Primary HPV Cervical Cancer Screening: Supporting data and guidance updates
      Primary HPV Cervical Cancer Screening: Supporting data and guidance...
      Date: Tuesday, February 10th, 2015Time: 9:00AM PST, 12:00PM ESTFor the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology ...
      Speaker: Julia Engstrom-Melnyk, PhD
      Sponsored By: Roche Molecular Diagnostics, Roche Molecular Diagnostics
      10 24
      FEB 05, 2015 | 12:00 PM
      C.E. CREDITS
      The importance of pre-operative assessment and post-operative care in surgical procedures
      The importance of pre-operative assessment and post-operative...
      The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
      Speaker: Pilar Ariza Guzman, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      6
      FEB 04, 2015 | 1:30 PM
      C.E. CREDITS
      The Surgeons Toolbox: outcomes are only as good as the contents of the box
      The Surgeons Toolbox: outcomes are only as good as the contents...
      The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 10:30 AM
      C.E. CREDITS
      Keynote: Practical Tips to Optimize Surgical Results in Rodents
      Keynote: Practical Tips to Optimize Surgical Results in Rodents
      It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
      Speaker: Marcel Perret-Gentil, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 6:00 AM
      C.E. CREDITS
      PCR testing in rodent health monitoring program: where are we exactly?
      PCR testing in rodent health monitoring program: where are we...
      Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
      Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      33
      NOV 12, 2014 | 8:00 AM
      Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
      Hallmarks of cancer - Detect and quantify cell death signatures...
      Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
      Speaker: Oliver Kepp, PhD and Jayne A. Hesley
      Sponsored By: Molecular Devices, Molecular Devices
      33
      OCT 30, 2014 | 3:00 PM
      Probing cancer metabolism using isotope tracers to identify therapeutic targets
      Probing cancer metabolism using isotope tracers to identify therapeutic...
      Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
      Speaker: Christian Metallo, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 3:00 PM
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
      Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
      Speaker: Josip Blonder, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      30
      OCT 30, 2014 | 1:30 PM
      Dissecting cancer signaling pathways with chemical scalpels
      Dissecting cancer signaling pathways with chemical scalpels
      Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
      Speaker: Nadya Tarasova, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 30, 2014 | 1:30 PM
      Structural Pathways of Cancer
      Structural Pathways of Cancer
      Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
      Speaker: Ruth Nussinov, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 12:00 PM
      The metabolic microenvironment in tumors and its impact on T-cell mediated immunity
      The metabolic microenvironment in tumors and its impact on T-cell...
      It has become widely accepted that the presence of intraepithelial CD8+ T cell correlate with improved patient survival. In contrast, tumors largely devoid of immune infiltrations or infiltra...
      Speaker: Julian J. Lum, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 30, 2014 | 12:00 PM
      Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
      Breast-Predict: Leveraging the Power of Systems Medicine Towards...
      Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
      Speaker: William M. Gallagher, BSc PhD CBiol MSB
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 10:30 AM
      Genomics in the Clinic: Promises and Challenges
      Genomics in the Clinic: Promises and Challenges
      Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
      Speaker: John Carpten, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 9:00 AM
      A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
      A head-to-head comparison of whole blood derived samples (cfDNA...
      Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
      Speaker: Paul W. Dempsey, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 30, 2014 | 7:30 AM
      Challenges in biomarker testing in non-small cell lung cancer research
      Challenges in biomarker testing in non-small cell lung cancer...
      Fusion genes play a central role in many cancer types. They have been used to classify malignancy, risk factors, disease prognosis, and companion diagnostic biomarkers for certain approved dr...
      Speaker: Nicola Normanno, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 30, 2014 | 6:00 AM
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
      When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      8
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 1:30 PM
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
      Speaker: Walter Ausserer, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      50
      OCT 29, 2014 | 1:30 PM
      Metabolic therapy for the adjuvant treatment of malignant brain tumors
      Metabolic therapy for the adjuvant treatment of malignant brain...
      Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
      Speaker: Adrienne C. Scheck, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 1:30 PM
      Protein phosphatase 2A in cell survival upon metabolic stress
      Protein phosphatase 2A in cell survival upon metabolic stress
      Tumor cells often display fundamental changes in metabolism and increase their uptake of nutrients to meet the increased bioenergetic demands of proliferation. Glucose and glutamine are two m...
      Speaker: Mei Kong, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 29, 2014 | 12:00 PM
      Obesity, weight loss, and the microenvironment in basal-like breast cancer
      Obesity, weight loss, and the microenvironment in basal-like breast...
      Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
      Speaker: Liza Makowski, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 7:30 AM
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
      The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
      Speaker: Darran O'Connor, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 7:30 AM
      Making Clinical NGS possible
      Making Clinical NGS possible
      Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
      Speaker: Vikram Devgan, PhD, MBA
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
    FEB 10, 2015 | 12:00 PM
    Primary HPV Cervical Cancer Screening: Supporting data and guidance updates
    Primary HPV Cervical Cancer Screening: Supporting data and guidance...
    Date: Tuesday, February 10th, 2015Time: 12:00PM PST, 3:00PM ESTFor the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology ...
    Speaker: Julia Engstrom-Melnyk, PhD
    Sponsored By: Roche Molecular Diagnostics, Roche Molecular Diagnostics
    8 5
    FEB 10, 2015 | 9:00 AM
    Primary HPV Cervical Cancer Screening: Supporting data and guidance updates
    Primary HPV Cervical Cancer Screening: Supporting data and guidance...
    Date: Tuesday, February 10th, 2015Time: 9:00AM PST, 12:00PM ESTFor the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology ...
    Speaker: Julia Engstrom-Melnyk, PhD
    Sponsored By: Roche Molecular Diagnostics, Roche Molecular Diagnostics
    10 24
    FEB 05, 2015 | 12:00 PM
    C.E. CREDITS
    The importance of pre-operative assessment and post-operative care in surgical procedures
    The importance of pre-operative assessment and post-operative...
    The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
    Speaker: Pilar Ariza Guzman, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    6
    FEB 04, 2015 | 1:30 PM
    C.E. CREDITS
    The Surgeons Toolbox: outcomes are only as good as the contents of the box
    The Surgeons Toolbox: outcomes are only as good as the contents...
    The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
    FEB 04, 2015 | 10:30 AM
    C.E. CREDITS
    Keynote: Practical Tips to Optimize Surgical Results in Rodents
    Keynote: Practical Tips to Optimize Surgical Results in Rodents
    It is the often-ignored simple tips in rodent surgery that make the difference and help minimize postoperative complications and mortality. The presenter will use his years of experience to...
    Speaker: Marcel Perret-Gentil, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
     
     
  • FEB 04, 2015 | 6:00 AM
    C.E. CREDITS
    PCR testing in rodent health monitoring program: where are we exactly?
    PCR testing in rodent health monitoring program: where are we...
    Soiled-bedding sentinels are not always efficient in detecting pathogens in rodent colonies. In this context, PCR-based testing can be more sensitive and is being advocated as adjunct to trad...
    Speaker: Mathias Leblanc, DVM, PhD, DES, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    33
    NOV 12, 2014 | 8:00 AM
    Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
    Hallmarks of cancer - Detect and quantify cell death signatures...
    Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
    Speaker: Oliver Kepp, PhD and Jayne A. Hesley
    Sponsored By: Molecular Devices, Molecular Devices
    33
    OCT 30, 2014 | 3:00 PM
    Probing cancer metabolism using isotope tracers to identify therapeutic targets
    Probing cancer metabolism using isotope tracers to identify therapeutic...
    Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
    Speaker: Christian Metallo, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 3:00 PM
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
    Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
    Speaker: Josip Blonder, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    30
    OCT 30, 2014 | 1:30 PM
    Dissecting cancer signaling pathways with chemical scalpels
    Dissecting cancer signaling pathways with chemical scalpels
    Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
    Speaker: Nadya Tarasova, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
     
     
  • OCT 30, 2014 | 1:30 PM
    Structural Pathways of Cancer
    Structural Pathways of Cancer
    Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
    Speaker: Ruth Nussinov, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 12:00 PM
    The metabolic microenvironment in tumors and its impact on T-cell mediated immunity
    The metabolic microenvironment in tumors and its impact on T-cell...
    It has become widely accepted that the presence of intraepithelial CD8+ T cell correlate with improved patient survival. In contrast, tumors largely devoid of immune infiltrations or infiltra...
    Speaker: Julian J. Lum, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 30, 2014 | 12:00 PM
    Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
    Breast-Predict: Leveraging the Power of Systems Medicine Towards...
    Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
    Speaker: William M. Gallagher, BSc PhD CBiol MSB
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 10:30 AM
    Genomics in the Clinic: Promises and Challenges
    Genomics in the Clinic: Promises and Challenges
    Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
    Speaker: John Carpten, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 9:00 AM
    A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
    A head-to-head comparison of whole blood derived samples (cfDNA...
    Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
    Speaker: Paul W. Dempsey, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
     
     
  • OCT 30, 2014 | 7:30 AM
    Challenges in biomarker testing in non-small cell lung cancer research
    Challenges in biomarker testing in non-small cell lung cancer...
    Fusion genes play a central role in many cancer types. They have been used to classify malignancy, risk factors, disease prognosis, and companion diagnostic biomarkers for certain approved dr...
    Speaker: Nicola Normanno, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 30, 2014 | 6:00 AM
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
    When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    8
    OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 1:30 PM
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
    Speaker: Walter Ausserer, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    50
    OCT 29, 2014 | 1:30 PM
    Metabolic therapy for the adjuvant treatment of malignant brain tumors
    Metabolic therapy for the adjuvant treatment of malignant brain...
    Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
    Speaker: Adrienne C. Scheck, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
     
     
  • OCT 29, 2014 | 1:30 PM
    Protein phosphatase 2A in cell survival upon metabolic stress
    Protein phosphatase 2A in cell survival upon metabolic stress
    Tumor cells often display fundamental changes in metabolism and increase their uptake of nutrients to meet the increased bioenergetic demands of proliferation. Glucose and glutamine are two m...
    Speaker: Mei Kong, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 29, 2014 | 12:00 PM
    Obesity, weight loss, and the microenvironment in basal-like breast cancer
    Obesity, weight loss, and the microenvironment in basal-like breast...
    Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
    Speaker: Liza Makowski, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 29, 2014 | 7:30 AM
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
    The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
    Speaker: Darran O'Connor, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 29, 2014 | 7:30 AM
    Making Clinical NGS possible
    Making Clinical NGS possible
    Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
    Speaker: Vikram Devgan, PhD, MBA
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
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