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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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APR 09, 2018Drug Discovery & Development
Transthyretin amyloidosis (ATTR) is a slowly progressive disease characterized by the buildup of abnormal deposits of a ...Written By: Nouran AminAPR 09, 2018Immunology
An important cellular reaction mediates part of the immune system responsible for tolerance. Without tolerance, the immu ...Written By: Kara MarkerAPR 08, 2018Microbiology
This new kind of compound acts in a unique way, and may be effective against drug-resistant bacteria.Written By: Carmen LeitchAPR 08, 2018Cannabis Sciences
According to the 2016 National Survey of Children's Health, there are 5.4 million children with a current dia ...Written By: Melissa MooreAPR 07, 2018Cell & Molecular Biology
Organoids are miniature versions of human organs that are advancing the study of biology. These 3D structures are an exc ...Written By: Carmen LeitchAPR 07, 2018Cardiology
The immune cells that are partly responsible for clogging arteries in a disease called atherosclerosis are under investi ...Written By: Kara MarkerAPR 06, 2018Cancer
The Cancer Genome Atlas project used genomic profiles and bioinformatics to catalogue 33 prevalent types of cancer and i ...Written By: Mauri BrueggemanAPR 05, 2018Cell & Molecular Biology
Astrocytes are a special type of brain cell; shaped like stars, they are thought to have a critical role in the developm ...Written By: Carmen LeitchAPR 03, 2018Cancer
Carbon-Ion Radiotherapy continues to be investigated but shows promise in treating some types of refractory or radiation ...Written By: Mauri BrueggemanAPR 02, 2018Drug Discovery & Development
DNA-encoded chemical library (DECL), containing about 35 million different drugs, is a new screening method devel ...Written By: Nouran AminAPR 02, 2018Cell & Molecular Biology
Eggshells are a marvel of nature; they can resist breakage by outside forces, yet will easily crack open from the inside ...Written By: Carmen LeitchAPR 01, 2018Genetics & Genomics
This work could help create cells that work as therapeutics for heart damage.Written By: Carmen LeitchMAR 29, 2018Immunology
Regulating inflammation is vital for controlling various autoimmune and inflammatory diseases. Inflammation is important ...Written By: Kara MarkerMAR 28, 2018Neuroscience
Many neurological conditions are progressive. The disease begins, perhaps mildly at first, but then gets worse. This is ...Written By: Brenda Kelley KimMAR 25, 2018Drug Discovery & Development
Researchers have discovered a crucial step in blood digestion of hookworms that feed and infect the blood of mice. The k ...Written By: Nouran AminMAR 25, 2018Drug Discovery & Development
Mesothelioma is an aggressive and deadly form of cancer that occurs in the outer linings of the internal organs, particu ...Written By: Nouran AminMAR 24, 2018Microbiology
An anti-bacterial chemical commonly used in toiletries is effective as an anti-malaria drug, even in drug-resistant para ...Written By: Carmen LeitchMAR 23, 2018Immunology
A supposedly rare genetic mutation that provides protection from malaria is actually present in one-third of people of A ...Written By: Kara MarkerMAR 22, 2018Neuroscience
It takes nine months for a baby to grow from a few cells to a full-term newborn and there’s a lot going on during ...Written By: Brenda Kelley KimMAR 17, 2018Clinical & Molecular DX
Before new drugs are tested in humans, researchers have to ensure that they are both effective and safe. Animal models o ...Written By: Kara MarkerMAR 16, 2018Cell & Molecular Biology
This new tool, SPLiT-seq, uses barcoding to tease out the genetic information in individual cells within tissue.Written By: Carmen LeitchMAR 16, 2018Technology
Mice showed ~100% tumor shrinkage with LANT method developed by Dr. Hadiyah-Nicole Green.Written By: Julia TraversMAR 15, 2018Health & Medicine
For the first time, a form of medicinal cannabis has been shown to reduce—and even stop—seizures in some chi ...Written By: Invisiverse PuccioMAR 15, 2018Cannabis Sciences
Chemists have synthesized several variants of THC, the active ingredient in cannabis. The ability to alter its structure ...Written By: Invisiverse Puccio
APR 09, 2018
Drug Discovery & Development
Transthyretin amyloidosis (ATTR) is a slowly progressive disease characterized by the buildup of abnormal deposits of a
...
Written By:
Nouran Amin
APR 09, 2018
Immunology
An important cellular reaction mediates part of the immune system responsible for tolerance. Without tolerance, the immu
...
Written By:
Kara Marker
APR 08, 2018
Microbiology
This new kind of compound acts in a unique way, and may be effective against drug-resistant bacteria.
Written By:
Carmen Leitch
APR 08, 2018
Cannabis Sciences
According to the 2016 National Survey of Children's Health, there are 5.4 million children with a current dia
...
Written By:
Melissa Moore
APR 07, 2018
Cell & Molecular Biology
Organoids are miniature versions of human organs that are advancing the study of biology. These 3D structures are an exc
...
Written By:
Carmen Leitch
APR 07, 2018
Cardiology
The immune cells that are partly responsible for clogging arteries in a disease called atherosclerosis are under investi
...
Written By:
Kara Marker
APR 06, 2018
Cancer
The Cancer Genome Atlas project used genomic profiles and bioinformatics to catalogue 33 prevalent types of cancer and i
...
Written By:
Mauri Brueggeman
APR 05, 2018
Cell & Molecular Biology
Astrocytes are a special type of brain cell; shaped like stars, they are thought to have a critical role in the developm
...
Written By:
Carmen Leitch
APR 03, 2018
Cancer
Carbon-Ion Radiotherapy continues to be investigated but shows promise in treating some types of refractory or radiation
...
Written By:
Mauri Brueggeman
APR 02, 2018
Drug Discovery & Development
DNA-encoded chemical library (DECL), containing about 35 million different drugs, is a new screening method devel
...
Written By:
Nouran Amin
APR 02, 2018
Cell & Molecular Biology
Eggshells are a marvel of nature; they can resist breakage by outside forces, yet will easily crack open from the inside
...
Written By:
Carmen Leitch
APR 01, 2018
Genetics & Genomics
This work could help create cells that work as therapeutics for heart damage.
Written By:
Carmen Leitch
MAR 29, 2018
Immunology
Regulating inflammation is vital for controlling various autoimmune and inflammatory diseases. Inflammation is important
...
Written By:
Kara Marker
MAR 28, 2018
Neuroscience
Many neurological conditions are progressive. The disease begins, perhaps mildly at first, but then gets worse. This is
...
Written By:
Brenda Kelley Kim
MAR 25, 2018
Drug Discovery & Development
Researchers have discovered a crucial step in blood digestion of hookworms that feed and infect the blood of mice. The k
...
Written By:
Nouran Amin
MAR 25, 2018
Drug Discovery & Development
Mesothelioma is an aggressive and deadly form of cancer that occurs in the outer linings of the internal organs, particu
...
Written By:
Nouran Amin
MAR 24, 2018
Microbiology
An anti-bacterial chemical commonly used in toiletries is effective as an anti-malaria drug, even in drug-resistant para
...
Written By:
Carmen Leitch
MAR 23, 2018
Immunology
A supposedly rare genetic mutation that provides protection from malaria is actually present in one-third of people of A
...
Written By:
Kara Marker
MAR 22, 2018
Neuroscience
It takes nine months for a baby to grow from a few cells to a full-term newborn and there’s a lot going on during
...
Written By:
Brenda Kelley Kim
MAR 17, 2018
Clinical & Molecular DX
Before new drugs are tested in humans, researchers have to ensure that they are both effective and safe. Animal models o
...
Written By:
Kara Marker
MAR 16, 2018
Cell & Molecular Biology
This new tool, SPLiT-seq, uses barcoding to tease out the genetic information in individual cells within tissue.
Written By:
Carmen Leitch
MAR 16, 2018
Technology
Mice showed ~100% tumor shrinkage with LANT method developed by Dr. Hadiyah-Nicole Green.
Written By:
Julia Travers
MAR 15, 2018
Health & Medicine
For the first time, a form of medicinal cannabis has been shown to reduce—and even stop—seizures in some chi
...
Written By:
Invisiverse Puccio
MAR 15, 2018
Cannabis Sciences
Chemists have synthesized several variants of THC, the active ingredient in cannabis. The ability to alter its structure
...
Written By:
Invisiverse Puccio