Follow
Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
-
FEB 15, 2018Cell & Molecular Biology
CRISPR technology continues to revolutionize biology; two new diagnostic tools based on the technique have now been deve ...Written By: Carmen LeitchFEB 13, 2018Neuroscience
When the brain is developing, stem cells, the building blocks of everything, are actively producing cellular offspring i ...Written By: Brenda Kelley KimFEB 10, 2018Videos
Researchers were able, for the first time, to grow early-stage human egg cells in the laboratory until they were fully m ...Written By: Carmen LeitchFEB 09, 2018Health & Medicine
It's not uncommon for people to have a glass of wine after a long day, or when at social functions. The choice to ha ...Written By: Brenda Kelley KimFEB 08, 2018Cell & Molecular Biology
There may come a time when people won't require surgery to replace their joints.Written By: Carmen LeitchFEB 06, 2018Immunology
Scientists continue to build upon a vaccine candidate to prevent HIV infection, the virus that causes AIDS. AIDSVAX was ...Written By: Kara MarkerFEB 06, 2018Clinical & Molecular DX
Two key factors implicated in the development of bipolar disorder (BD) are connected, researchers involved in a new stud ...Written By: Kara MarkerFEB 05, 2018Neuroscience
Alzheimer's disease (AD) is a progressive, neurodegenerative disease, for which there is no cure. Hundreds of resear ...Written By: Brenda Kelley KimFEB 04, 2018Genetics & Genomics
At some point organisms changed, and grew from a single cell into one made up of many cells. But how that happened is no ...Written By: Carmen LeitchFEB 03, 2018Microbiology
Zika virus only impacts six to twelve percent of children born to infected mothers. Researchers are learning exactly why ...Written By: Carmen LeitchFEB 01, 2018Cell & Molecular Biology
Kids with autism are less social, and one researcher adapted a common game to learn more about why.Written By: Carmen LeitchJAN 31, 2018Neuroscience
Getting medication to the brain can be a tricky business. The blood-brain-barrier is designed to prevent toxic substance ...Written By: Brenda Kelley KimJAN 30, 2018Microbiology
As babies crawl around on floors, the action kicks up a lot of stuff. Skin cells, dirt, bacteria, pollen and fungal spor ...Written By: Carmen LeitchJAN 29, 2018Cardiology
Early during development as the embryo begins to form, the heart is the first organ to materialize. So-called “pro ...Written By: Kara MarkerJAN 26, 2018Chemistry & Physics
Solar cells are the basic power-generating units within a typical solar panel. It converts the energy of sunlight direct ...Written By: Daniel DuanJAN 26, 2018Cardiology
After a heart attack, heart cells lose sensitivity. According to recent discoveries from Queen Mary University of London ...Written By: Kara MarkerJAN 24, 2018Genetics & Genomics
Two identical primates have been cloned using a technique called somatic cell nuclear transfer (SCNT), the same tool use ...Written By: Carmen LeitchJAN 24, 2018Cell & Molecular Biology
Stem cells hold a tremendous amount of research promise. Now researchers have found a very easy way to create them.Written By: Carmen LeitchJAN 24, 2018Immunology
Sometimes it’s hard to convince people to get the annual flu vaccine, especially when the current vaccine struggle ...Written By: Kara MarkerJAN 20, 2018Cardiology
One small molecule called nitric oxide (NO) plays so many different roles in the cell, valuable and destructive. Scienti ...Written By: Kara MarkerJAN 19, 2018Genetics & Genomics
For the first time, scientists have captred images of the process by which DNA is transcribed into RNAWritten By: Carmen LeitchJAN 19, 2018Immunology
A group of scientists are studying all things type 1 diabetes, looking for causation - genetic and environmental - as we ...Written By: Kara MarkerJAN 18, 2018Drug Discovery & Development
Brief overview of Ewing sarcoma therapeuticsWritten By: Courtney SchaalJAN 17, 2018Immunology
The high fat, high calorie, and low fiber diet commonly referred to as the “Western diet” has long been asso ...Written By: Kara Marker
FEB 15, 2018
Cell & Molecular Biology
CRISPR technology continues to revolutionize biology; two new diagnostic tools based on the technique have now been deve
...
Written By:
Carmen Leitch
FEB 13, 2018
Neuroscience
When the brain is developing, stem cells, the building blocks of everything, are actively producing cellular offspring i
...
Written By:
Brenda Kelley Kim
FEB 10, 2018
Videos
Researchers were able, for the first time, to grow early-stage human egg cells in the laboratory until they were fully m
...
Written By:
Carmen Leitch
FEB 09, 2018
Health & Medicine
It's not uncommon for people to have a glass of wine after a long day, or when at social functions. The choice to ha
...
Written By:
Brenda Kelley Kim
FEB 08, 2018
Cell & Molecular Biology
There may come a time when people won't require surgery to replace their joints.
Written By:
Carmen Leitch
FEB 06, 2018
Immunology
Scientists continue to build upon a vaccine candidate to prevent HIV infection, the virus that causes AIDS. AIDSVAX was
...
Written By:
Kara Marker
FEB 06, 2018
Clinical & Molecular DX
Two key factors implicated in the development of bipolar disorder (BD) are connected, researchers involved in a new stud
...
Written By:
Kara Marker
FEB 05, 2018
Neuroscience
Alzheimer's disease (AD) is a progressive, neurodegenerative disease, for which there is no cure. Hundreds of resear
...
Written By:
Brenda Kelley Kim
FEB 04, 2018
Genetics & Genomics
At some point organisms changed, and grew from a single cell into one made up of many cells. But how that happened is no
...
Written By:
Carmen Leitch
FEB 03, 2018
Microbiology
Zika virus only impacts six to twelve percent of children born to infected mothers. Researchers are learning exactly why
...
Written By:
Carmen Leitch
FEB 01, 2018
Cell & Molecular Biology
Kids with autism are less social, and one researcher adapted a common game to learn more about why.
Written By:
Carmen Leitch
JAN 31, 2018
Neuroscience
Getting medication to the brain can be a tricky business. The blood-brain-barrier is designed to prevent toxic substance
...
Written By:
Brenda Kelley Kim
JAN 30, 2018
Microbiology
As babies crawl around on floors, the action kicks up a lot of stuff. Skin cells, dirt, bacteria, pollen and fungal spor
...
Written By:
Carmen Leitch
JAN 29, 2018
Cardiology
Early during development as the embryo begins to form, the heart is the first organ to materialize. So-called “pro
...
Written By:
Kara Marker
JAN 26, 2018
Chemistry & Physics
Solar cells are the basic power-generating units within a typical solar panel. It converts the energy of sunlight direct
...
Written By:
Daniel Duan
JAN 26, 2018
Cardiology
After a heart attack, heart cells lose sensitivity. According to recent discoveries from Queen Mary University of London
...
Written By:
Kara Marker
JAN 24, 2018
Genetics & Genomics
Two identical primates have been cloned using a technique called somatic cell nuclear transfer (SCNT), the same tool use
...
Written By:
Carmen Leitch
JAN 24, 2018
Cell & Molecular Biology
Stem cells hold a tremendous amount of research promise. Now researchers have found a very easy way to create them.
Written By:
Carmen Leitch
JAN 24, 2018
Immunology
Sometimes it’s hard to convince people to get the annual flu vaccine, especially when the current vaccine struggle
...
Written By:
Kara Marker
JAN 20, 2018
Cardiology
One small molecule called nitric oxide (NO) plays so many different roles in the cell, valuable and destructive. Scienti
...
Written By:
Kara Marker
JAN 19, 2018
Genetics & Genomics
For the first time, scientists have captred images of the process by which DNA is transcribed into RNA
Written By:
Carmen Leitch
JAN 19, 2018
Immunology
A group of scientists are studying all things type 1 diabetes, looking for causation - genetic and environmental - as we
...
Written By:
Kara Marker
JAN 18, 2018
Drug Discovery & Development
Brief overview of Ewing sarcoma therapeutics
Written By:
Courtney Schaal
JAN 17, 2018
Immunology
The high fat, high calorie, and low fiber diet commonly referred to as the “Western diet” has long been asso
...
Written By:
Kara Marker