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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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AUG 24, 2017Microbiology
Scientists are learning more about the specialized microbiomes of elite athletes.Written By: Carmen LeitchAUG 23, 2017Cardiology
Self-driving cars? How about self-healing heart cells? For a while scientists have been looking for ways to help heart c ...Written By: Kara MarkerAUG 22, 2017Plants & Animals
Climate change is a major concern for environmentalists; one of the things they do is try to protect wildlife from succu ...Written By: Anthony BouchardAUG 21, 2017Cardiology
A heart attack wounds the heart similar to the way a deep cut wounds the skin: it leaves a scar. However, a scar on the ...Written By: Kara MarkerAUG 21, 2017Cell & Molecular Biology
Our genomic material is in a constant state of replication, and errors in that process have been linked to disease. New ...Written By: Carmen LeitchAUG 19, 2017Cell & Molecular Biology
New work is upending an old theory about the development of sex-specific mammalian reproductive systems.Written By: Carmen LeitchAUG 16, 2017Cardiology
Heart attack patients can be given regenerative tissue to help them recover, but the current procedure involves open-hea ...Written By: Kara MarkerAUG 16, 2017Immunology
A vaccine for yellow fever was first developed in 1937, using a strain of the yellow fever virus that was just a few ami ...Written By: Kara MarkerAUG 15, 2017Cardiology
Inflammation in the liver and boosted cholesterol levels in the blood vessels create the perfect storm for vascular dise ...Written By: Kara MarkerAUG 13, 2017Cell & Molecular Biology
Researchers have identified a drug that has slowed the progression of a rare genetic disease in clinical trials.Written By: Carmen LeitchAUG 13, 2017Videos
In this video, you can see a 2017 Koch Institute Image Award winner, "Body of Knowledge." This research is part of the D ...Written By: Carmen LeitchAUG 12, 2017Immunology
Immune cells all over the body protect native human cells from pathogens like bacteria and viruses, but in the testis, i ...Written By: Kara MarkerAUG 12, 2017Cancer
Chemotherapy works against cancer by poisoning the cells. As such, few chemotherapy agents are safely prescribed to expe ...AUG 09, 2017Immunology
Too much inflammation in the gut triggers inflammatory bowel disease (IBD). There are immune cells specifically designed ...Written By: Kara MarkerAUG 06, 2017Cell & Molecular Biology
This new molecule doesn't have to enter the cell to exert an effect.Written By: Carmen LeitchAUG 04, 2017Cell & Molecular Biology
One reason cancer is so deadly is that cancer cells can break away from where they originated and spread disease through ...Written By: Carmen LeitchAUG 04, 2017Immunology
An intricate relationship between the gastrointestinal (GI) tract and the part of the brain that senses smell contribute ...Written By: Kara MarkerAUG 02, 2017Cell & Molecular Biology
Researchers have made a breakthrough by successfully repairing a deleterious genetic mutation in a human embryo that cau ...Written By: Carmen LeitchAUG 02, 2017Cancer
Turmeric, the trendy spicy that’s making its way into lattes, could be key in defeating pancreatic cancer drug res ...JUL 29, 2017Cell & Molecular Biology
There is a massive effort to sequence the genomes of thousands of plants, part of a bigger effort to gather more genomic ...Written By: Carmen LeitchJUL 28, 2017Plants & Animals
Tardigrades are fascinating organisms, not just because they would likely survive almost any cataclysmic event that&rsqu ...Written By: Anthony BouchardJUL 27, 2017Cancer
Brain cancer is on higher on the discussion list this week after news broke of Senator John McCain’s recent gliobl ...JUL 26, 2017Cardiology
The hormone responsible for preventing us from constant eating and keeping us at a healthy weight apparently also plays ...Written By: Kara MarkerJUL 25, 2017Cell & Molecular Biology
A new study suggests that sex differences should be taken into account when determining treatments for severe antisocial ...Written By: Carmen Leitch
AUG 24, 2017
Microbiology
Scientists are learning more about the specialized microbiomes of elite athletes.
Written By:
Carmen Leitch
AUG 23, 2017
Cardiology
Self-driving cars? How about self-healing heart cells? For a while scientists have been looking for ways to help heart c
...
Written By:
Kara Marker
AUG 22, 2017
Plants & Animals
Climate change is a major concern for environmentalists; one of the things they do is try to protect wildlife from succu
...
Written By:
Anthony Bouchard
AUG 21, 2017
Cardiology
A heart attack wounds the heart similar to the way a deep cut wounds the skin: it leaves a scar. However, a scar on the
...
Written By:
Kara Marker
AUG 21, 2017
Cell & Molecular Biology
Our genomic material is in a constant state of replication, and errors in that process have been linked to disease. New
...
Written By:
Carmen Leitch
AUG 19, 2017
Cell & Molecular Biology
New work is upending an old theory about the development of sex-specific mammalian reproductive systems.
Written By:
Carmen Leitch
AUG 16, 2017
Cardiology
Heart attack patients can be given regenerative tissue to help them recover, but the current procedure involves open-hea
...
Written By:
Kara Marker
AUG 16, 2017
Immunology
A vaccine for yellow fever was first developed in 1937, using a strain of the yellow fever virus that was just a few ami
...
Written By:
Kara Marker
AUG 15, 2017
Cardiology
Inflammation in the liver and boosted cholesterol levels in the blood vessels create the perfect storm for vascular dise
...
Written By:
Kara Marker
AUG 13, 2017
Cell & Molecular Biology
Researchers have identified a drug that has slowed the progression of a rare genetic disease in clinical trials.
Written By:
Carmen Leitch
AUG 13, 2017
Videos
In this video, you can see a 2017 Koch Institute Image Award winner, "Body of Knowledge." This research is part of the D
...
Written By:
Carmen Leitch
AUG 12, 2017
Immunology
Immune cells all over the body protect native human cells from pathogens like bacteria and viruses, but in the testis, i
...
Written By:
Kara Marker
AUG 12, 2017
Cancer
Chemotherapy works against cancer by poisoning the cells. As such, few chemotherapy agents are safely prescribed to expe
...
AUG 09, 2017
Immunology
Too much inflammation in the gut triggers inflammatory bowel disease (IBD). There are immune cells specifically designed
...
Written By:
Kara Marker
AUG 06, 2017
Cell & Molecular Biology
This new molecule doesn't have to enter the cell to exert an effect.
Written By:
Carmen Leitch
AUG 04, 2017
Cell & Molecular Biology
One reason cancer is so deadly is that cancer cells can break away from where they originated and spread disease through
...
Written By:
Carmen Leitch
AUG 04, 2017
Immunology
An intricate relationship between the gastrointestinal (GI) tract and the part of the brain that senses smell contribute
...
Written By:
Kara Marker
AUG 02, 2017
Cell & Molecular Biology
Researchers have made a breakthrough by successfully repairing a deleterious genetic mutation in a human embryo that cau
...
Written By:
Carmen Leitch
AUG 02, 2017
Cancer
Turmeric, the trendy spicy that’s making its way into lattes, could be key in defeating pancreatic cancer drug res
...
JUL 29, 2017
Cell & Molecular Biology
There is a massive effort to sequence the genomes of thousands of plants, part of a bigger effort to gather more genomic
...
Written By:
Carmen Leitch
JUL 28, 2017
Plants & Animals
Tardigrades are fascinating organisms, not just because they would likely survive almost any cataclysmic event that&rsqu
...
Written By:
Anthony Bouchard
JUL 27, 2017
Cancer
Brain cancer is on higher on the discussion list this week after news broke of Senator John McCain’s recent gliobl
...
JUL 26, 2017
Cardiology
The hormone responsible for preventing us from constant eating and keeping us at a healthy weight apparently also plays
...
Written By:
Kara Marker
JUL 25, 2017
Cell & Molecular Biology
A new study suggests that sex differences should be taken into account when determining treatments for severe antisocial
...
Written By:
Carmen Leitch