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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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NOV 29, 2016Microbiology
Many of our drugs are derived from stuff found in nature, and as the development of new drugs becomes more critical to p ...Written By: Carmen LeitchNOV 28, 2016Microbiology
By using a vulnerability they found in the genetic code of venezuelan equine encephalitis virus (VEEV), researchers were ...Written By: Carmen LeitchNOV 28, 2016Cell & Molecular Biology
An organism is dependent on the replenishment and maintenance of cellular proteins in order to survive. One family of pr ...Written By: Carmen LeitchNOV 28, 2016Cancer
A cancer drug that’s approved for the treatment of kidney cancer may also be effective against a form of muscular ...NOV 28, 2016Neuroscience
There was disappointing news recently on a drug many had hoped would provide some relief for patients suffering with Alz ...Written By: Brenda Kelley KimNOV 25, 2016Cell & Molecular Biology
ALS, amyotrophic lateral sclerosis or Lou Gehrig’s disease, is a disorder of the nervous system; the nerve cells t ...Written By: Carmen LeitchNOV 23, 2016Cell & Molecular Biology
Reporting in Nature Medicine, researchers have been able to use stem cells to make intestinal organoids with functional ...Written By: Carmen LeitchNOV 23, 2016Cardiology
Many organisms are capable of regenerating limbs. Why not humans? New research could help humans experience the benefits ...Written By: Kara MarkerNOV 22, 2016Immunology
Thanks to immune soldiers called T cells, the body is protected from most infections: viral, bacterial, parasitical, or ...Written By: Kara MarkerNOV 20, 2016Cell & Molecular Biology
A study published in Cell demonstrated how the brains of patients with different kinds of autism spectrum disorder (ASD) ...Written By: Carmen LeitchNOV 20, 2016Microbiology
Using a special type of microscopy, researchers were able to capture changes in the nucleus of nerve cells as they under ...Written By: Carmen LeitchNOV 17, 2016Videos
Demonstrated in the video below, scientists have created a way to build artificial cells that could lead to the developm ...Written By: Carmen LeitchNOV 17, 2016Videos
At Johns Hopkins, new research into a molecule that targets specific proteins and makes tumors more sensitive to radiati ...Written By: Brenda Kelley KimNOV 16, 2016Cardiology
How do heart cells follow their genetic programming to create a heart? What can mice hearts do to help scientists unders ...Written By: Kara MarkerNOV 15, 2016Cell & Molecular Biology
Researchers at the University of Wisconsin - Madison have discovered a new protein that provides a critical link between ...Written By: Carmen LeitchNOV 15, 2016Cancer
Bacteria have all but hogged the limelight in our recent understanding of microbiomes and how these ecosystems influence ...NOV 14, 2016Immunology
Interferon drugs have long been used as treatments for multiple sclerosis (MS), an autoimmune disease where damaged nerv ...Written By: Kara MarkerNOV 14, 2016Cell & Molecular Biology
New work reported in Developmental Cell by researchers at Johns Hopkins University has demonstrated that a protein known ...Written By: Carmen LeitchNOV 14, 2016Cardiology
Three known transcription factors are capable of reprogramming connective tissue in the heart to transform scar tissue i ...Written By: Kara MarkerNOV 12, 2016Videos
The CRISPR/Cas9 genome technique has paved the way for the development of many biological advances not only in research, ...Written By: Carmen LeitchNOV 10, 2016Immunology
Two proteins serve as internal clocks for immune cells, a new system of regulation that defies most of what scientists t ...Written By: Kara MarkerNOV 09, 2016Microbiology
Urinary tract infections (UTIs), which are primarily caused by uropathogenic Escherichia coli (UPEC), are becoming more ...Written By: Carmen LeitchNOV 09, 2016Cell & Molecular Biology
A new report in Nature has shed some light on the process of necroptosis, a type of programmed cell death that is regula ...Written By: Carmen LeitchNOV 08, 2016Immunology
Could it be possible to predict the onset of type 1 diabetes before symptoms appear? If so, what kind of benefits would ...Written By: Kara Marker
NOV 29, 2016
Microbiology
Many of our drugs are derived from stuff found in nature, and as the development of new drugs becomes more critical to p
...
Written By:
Carmen Leitch
NOV 28, 2016
Microbiology
By using a vulnerability they found in the genetic code of venezuelan equine encephalitis virus (VEEV), researchers were
...
Written By:
Carmen Leitch
NOV 28, 2016
Cell & Molecular Biology
An organism is dependent on the replenishment and maintenance of cellular proteins in order to survive. One family of pr
...
Written By:
Carmen Leitch
NOV 28, 2016
Cancer
A cancer drug that’s approved for the treatment of kidney cancer may also be effective against a form of muscular
...
NOV 28, 2016
Neuroscience
There was disappointing news recently on a drug many had hoped would provide some relief for patients suffering with Alz
...
Written By:
Brenda Kelley Kim
NOV 25, 2016
Cell & Molecular Biology
ALS, amyotrophic lateral sclerosis or Lou Gehrig’s disease, is a disorder of the nervous system; the nerve cells t
...
Written By:
Carmen Leitch
NOV 23, 2016
Cell & Molecular Biology
Reporting in Nature Medicine, researchers have been able to use stem cells to make intestinal organoids with functional
...
Written By:
Carmen Leitch
NOV 23, 2016
Cardiology
Many organisms are capable of regenerating limbs. Why not humans? New research could help humans experience the benefits
...
Written By:
Kara Marker
NOV 22, 2016
Immunology
Thanks to immune soldiers called T cells, the body is protected from most infections: viral, bacterial, parasitical, or
...
Written By:
Kara Marker
NOV 20, 2016
Cell & Molecular Biology
A study published in Cell demonstrated how the brains of patients with different kinds of autism spectrum disorder (ASD)
...
Written By:
Carmen Leitch
NOV 20, 2016
Microbiology
Using a special type of microscopy, researchers were able to capture changes in the nucleus of nerve cells as they under
...
Written By:
Carmen Leitch
NOV 17, 2016
Videos
Demonstrated in the video below, scientists have created a way to build artificial cells that could lead to the developm
...
Written By:
Carmen Leitch
NOV 17, 2016
Videos
At Johns Hopkins, new research into a molecule that targets specific proteins and makes tumors more sensitive to radiati
...
Written By:
Brenda Kelley Kim
NOV 16, 2016
Cardiology
How do heart cells follow their genetic programming to create a heart? What can mice hearts do to help scientists unders
...
Written By:
Kara Marker
NOV 15, 2016
Cell & Molecular Biology
Researchers at the University of Wisconsin - Madison have discovered a new protein that provides a critical link between
...
Written By:
Carmen Leitch
NOV 15, 2016
Cancer
Bacteria have all but hogged the limelight in our recent understanding of microbiomes and how these ecosystems influence
...
NOV 14, 2016
Immunology
Interferon drugs have long been used as treatments for multiple sclerosis (MS), an autoimmune disease where damaged nerv
...
Written By:
Kara Marker
NOV 14, 2016
Cell & Molecular Biology
New work reported in Developmental Cell by researchers at Johns Hopkins University has demonstrated that a protein known
...
Written By:
Carmen Leitch
NOV 14, 2016
Cardiology
Three known transcription factors are capable of reprogramming connective tissue in the heart to transform scar tissue i
...
Written By:
Kara Marker
NOV 12, 2016
Videos
The CRISPR/Cas9 genome technique has paved the way for the development of many biological advances not only in research,
...
Written By:
Carmen Leitch
NOV 10, 2016
Immunology
Two proteins serve as internal clocks for immune cells, a new system of regulation that defies most of what scientists t
...
Written By:
Kara Marker
NOV 09, 2016
Microbiology
Urinary tract infections (UTIs), which are primarily caused by uropathogenic Escherichia coli (UPEC), are becoming more
...
Written By:
Carmen Leitch
NOV 09, 2016
Cell & Molecular Biology
A new report in Nature has shed some light on the process of necroptosis, a type of programmed cell death that is regula
...
Written By:
Carmen Leitch
NOV 08, 2016
Immunology
Could it be possible to predict the onset of type 1 diabetes before symptoms appear? If so, what kind of benefits would
...
Written By:
Kara Marker