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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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NOV 07, 2016Cell & Molecular Biology
New neurons in the brain of adult rodents are regulated by the blood vessels that are associated with them. Research tha ...Written By: Carmen LeitchNOV 07, 2016Earth & The Environment
A new study released by a team of researchers from the United Kingdom in Cell Press journal Current Biology have determi ...Written By: Kathryn DeMuth SullivanNOV 04, 2016Microbiology
Electron microscopy is a powerful tool that produces images of things magnified up to ten million times, but the images ...Written By: Carmen LeitchNOV 04, 2016Cancer
Seeking to unravel the mysteries surrounding ovarian cancer development, researchers at the University of Michigan ident ...NOV 03, 2016Cardiology
Risk factors leading to cardiovascular disease are often thought to be obesity, a sedentary lifestyle, and environmental ...Written By: Kara MarkerNOV 03, 2016Cancer
Adding to the astonishing list of organoids engineered in the lab, researchers at Cardiff University announced the devel ...NOV 02, 2016Cell & Molecular Biology
While interactions of biological molecules have been studied in depth. that work has not usually been done in the typica ...Written By: Carmen LeitchNOV 01, 2016Cardiology
Two interactive proteins were discovered in connection to atherosclerosis-related macrophage activation, according to a ...Written By: Kara MarkerNOV 01, 2016Microbiology
A new study from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (USDA HNRCA) has shown ...Written By: Carmen LeitchOCT 28, 2016Cell & Molecular Biology
A new report from Shinya Yamanaka, who won a Nobel Prize for his work on stem cells, has been published in the Proceedin ...Written By: Carmen LeitchOCT 27, 2016Cancer
Could stool samples reveal a person’s colorectal cancer risks? Researchers studying the molecular makeup of colon ...OCT 26, 2016Cell & Molecular Biology
Publishing in Cell Reports, researchers have identified a link between the molecular mechanism of Ewing’s sarcoma, ...Written By: Carmen LeitchOCT 25, 2016Cardiology
Studying the contractile forces of the human heart just got monumentally easier with the newest technology: 3D-printed h ...Written By: Kara MarkerOCT 25, 2016Videos
What, exactly, is albinism? Albinism is a collective term for many loosely related conditions. Everyone with albinism ma ...Written By: Kathryn DeMuth SullivanOCT 25, 2016Immunology
Next-generation sequencing revealed a rare protein deficiency from an inherited genetic mutation as the cause of a sever ...Written By: Kara MarkerOCT 24, 2016Cardiology
New imaging technology developed at Stanford University could help prevent strokes and heart attacks caused by severe at ...Written By: Kara MarkerOCT 24, 2016Cancer
In the world of drug development, finding new uses for old drugs seems like the ideal situation. But the road to repurpo ...OCT 22, 2016Cell & Molecular Biology
Modifications to DNA and RNA can exert a powerful influence on gene expression. The most modification to RNA, the interm ...Written By: Carmen LeitchOCT 21, 2016Microbiology
Biofilms form when microbes attach to a surface and adhere to each other, often inside of a matrix created by the cells ...Written By: Carmen LeitchOCT 21, 2016Clinical & Molecular DX
A new drug may lift hopes for many people plagued with a certain type of hair loss. In clinical trials, researchers have ...OCT 18, 2016Immunology
Since the 1960s, scientists have studied the antibody production and cell-mediated immune response duties of B lymphocyt ...Written By: Kara MarkerOCT 17, 2016Cardiology
For reasons not completely understood by scientists, our own heart muscle cells, called cardiomyocytes, secrete a protei ...Written By: Kara MarkerOCT 17, 2016Immunology
Image Credit: CDC JUPITER, FL – October 17, 2016 – In a study that could one day help eliminate the tragic b ...Written By: The Scripps Research Institute (TSRI)OCT 17, 2016Cardiology
Beams of light can replace painful electric shocks to restore normal heartbeat in people suffering from potentially fata ...Written By: Futurity (futurity.org)
NOV 07, 2016
Cell & Molecular Biology
New neurons in the brain of adult rodents are regulated by the blood vessels that are associated with them. Research tha
...
Written By:
Carmen Leitch
NOV 07, 2016
Earth & The Environment
A new study released by a team of researchers from the United Kingdom in Cell Press journal Current Biology have determi
...
Written By:
Kathryn DeMuth Sullivan
NOV 04, 2016
Microbiology
Electron microscopy is a powerful tool that produces images of things magnified up to ten million times, but the images
...
Written By:
Carmen Leitch
NOV 04, 2016
Cancer
Seeking to unravel the mysteries surrounding ovarian cancer development, researchers at the University of Michigan ident
...
NOV 03, 2016
Cardiology
Risk factors leading to cardiovascular disease are often thought to be obesity, a sedentary lifestyle, and environmental
...
Written By:
Kara Marker
NOV 03, 2016
Cancer
Adding to the astonishing list of organoids engineered in the lab, researchers at Cardiff University announced the devel
...
NOV 02, 2016
Cell & Molecular Biology
While interactions of biological molecules have been studied in depth. that work has not usually been done in the typica
...
Written By:
Carmen Leitch
NOV 01, 2016
Cardiology
Two interactive proteins were discovered in connection to atherosclerosis-related macrophage activation, according to a
...
Written By:
Kara Marker
NOV 01, 2016
Microbiology
A new study from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (USDA HNRCA) has shown
...
Written By:
Carmen Leitch
OCT 28, 2016
Cell & Molecular Biology
A new report from Shinya Yamanaka, who won a Nobel Prize for his work on stem cells, has been published in the Proceedin
...
Written By:
Carmen Leitch
OCT 27, 2016
Cancer
Could stool samples reveal a person’s colorectal cancer risks? Researchers studying the molecular makeup of colon
...
OCT 26, 2016
Cell & Molecular Biology
Publishing in Cell Reports, researchers have identified a link between the molecular mechanism of Ewing’s sarcoma,
...
Written By:
Carmen Leitch
OCT 25, 2016
Cardiology
Studying the contractile forces of the human heart just got monumentally easier with the newest technology: 3D-printed h
...
Written By:
Kara Marker
OCT 25, 2016
Videos
What, exactly, is albinism? Albinism is a collective term for many loosely related conditions. Everyone with albinism ma
...
Written By:
Kathryn DeMuth Sullivan
OCT 25, 2016
Immunology
Next-generation sequencing revealed a rare protein deficiency from an inherited genetic mutation as the cause of a sever
...
Written By:
Kara Marker
OCT 24, 2016
Cardiology
New imaging technology developed at Stanford University could help prevent strokes and heart attacks caused by severe at
...
Written By:
Kara Marker
OCT 24, 2016
Cancer
In the world of drug development, finding new uses for old drugs seems like the ideal situation. But the road to repurpo
...
OCT 22, 2016
Cell & Molecular Biology
Modifications to DNA and RNA can exert a powerful influence on gene expression. The most modification to RNA, the interm
...
Written By:
Carmen Leitch
OCT 21, 2016
Microbiology
Biofilms form when microbes attach to a surface and adhere to each other, often inside of a matrix created by the cells
...
Written By:
Carmen Leitch
OCT 21, 2016
Clinical & Molecular DX
A new drug may lift hopes for many people plagued with a certain type of hair loss. In clinical trials, researchers have
...
OCT 18, 2016
Immunology
Since the 1960s, scientists have studied the antibody production and cell-mediated immune response duties of B lymphocyt
...
Written By:
Kara Marker
OCT 17, 2016
Cardiology
For reasons not completely understood by scientists, our own heart muscle cells, called cardiomyocytes, secrete a protei
...
Written By:
Kara Marker
OCT 17, 2016
Immunology
Image Credit: CDC JUPITER, FL – October 17, 2016 – In a study that could one day help eliminate the tragic b
...
Written By:
The Scripps Research Institute (TSRI)
OCT 17, 2016
Cardiology
Beams of light can replace painful electric shocks to restore normal heartbeat in people suffering from potentially fata
...
Written By:
Futurity (futurity.org)