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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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DEC 20, 2016Cancer
JUPITER, FL – December 20, 2016 – Scientists from the Florida campus of The Scripps Research Institute (TSRI ...Written By: The Scripps Research Institute (TSRI)DEC 18, 2016Genetics & Genomics
How do lymphocytes make the decision to launch an attack or act otherwise? Researchers from the Weizmann Institute of Sc ...Written By: Kara MarkerDEC 18, 2016Microbiology
To construct new tissue or maintain it in adulthood, cells have to be able to respond to mechanical and molecular cues f ...Written By: Carmen LeitchDEC 18, 2016Cancer
The newest leukemia research findings suggest that intermittent fasting may literally starve the cancer cells too. The s ...DEC 17, 2016Cell & Molecular Biology
Females carry two X chromosomes, and the genes of one of those chromosomes cannot be expressed during development or myr ...Written By: Carmen LeitchDEC 17, 2016Cancer
If a cancer is caused by the over-activation of proteins that enhance growth, then blocking these enzymes should stunt t ...DEC 16, 2016Cell & Molecular Biology
Reporting in Cell, scientists were able to extend the lifespan of mice that carry a genetic mutation that causes prematu ...Written By: Carmen LeitchDEC 13, 2016Cell & Molecular Biology
Genetic information from genes on DNA is first transcribed into RNA before being made into proteins, the major building ...Written By: Carmen LeitchDEC 13, 2016Cell & Molecular Biology
Organisms depend on chemical cascades to perform the many life-sustaining functions of cells. Those cascades depend on p ...Written By: Carmen LeitchDEC 12, 2016Neuroscience
When a patient is diagnosed with Parkinson’s disease (PD) it can seem overwhelming. There is no known cause for PD ...Written By: Brenda Kelley KimDEC 11, 2016Videos
In this video from Mayo Clinic, researcher Dr. Shane Shapiro discusses his use of stem cells to treat osteoarthritis pai ...Written By: Carmen LeitchDEC 11, 2016Cell & Molecular Biology
Cell division is a fundamental process in life. Our cells must continually replicate, and that replication and growth ha ...Written By: Carmen LeitchDEC 09, 2016Cell & Molecular Biology
Reporting in Nature, researchers have created a way to move molecules between cells; they refer to this new technology a ...Written By: Carmen LeitchDEC 09, 2016Genetics & Genomics
Combat Obesity by Turning White Fat into Brown FatWritten By: Jennifer EllisDEC 07, 2016Chemistry & Physics
Using Photodynamic Therapy to Kill Hard-to-Reach TumorsWritten By: Jennifer EllisDEC 06, 2016Immunology
Scientists have discovered a cellular switch that can be turned “on” or “off,” which could be vi ...Written By: Kara MarkerDEC 05, 2016Microbiology
Researchers working at the Karolinska Institutet have made a breakthrough that will aid scientists studying biofilms. Th ...Written By: Carmen LeitchDEC 05, 2016Cell & Molecular Biology
Reporting in Nature Medicine, scientists at St. Jude Children's Research Hospital have determined that a small piece ...Written By: Carmen LeitchDEC 05, 2016Neuroscience
While there are many health problems related to alcohol use, the stakes are even higher when teenagers drink. The brain ...Written By: Brenda Kelley KimDEC 05, 2016Clinical & Molecular DX
LA JOLLA, CA – December 5, 2016 – A common class of drugs for vision loss may actually add to the problem in ...Written By: The Scripps Research Institute (TSRI)DEC 03, 2016Plants & Animals
Researchers have found a new class of photoreceptor protein known as LITE-1 in invertebrates that could be up to 50 time ...Written By: Anthony BouchardDEC 02, 2016Microbiology
Chemically, carbon and silicon are a lot alike; silicon can form bonds with four atoms at once and can create the long, ...Written By: Carmen LeitchDEC 01, 2016Cell & Molecular Biology
As the brain develops, neurons are created from a special type of neural stem call called radial glia. Researchers at Du ...Written By: Carmen LeitchNOV 30, 2016Cell & Molecular Biology
The Allen Institute for Cell Science was founded by a contribution by Paul G. Allen, a cofounder of Microsoft, in 2014. ...Written By: Carmen Leitch
DEC 20, 2016
Cancer
JUPITER, FL – December 20, 2016 – Scientists from the Florida campus of The Scripps Research Institute (TSRI
...
Written By:
The Scripps Research Institute (TSRI)
DEC 18, 2016
Genetics & Genomics
How do lymphocytes make the decision to launch an attack or act otherwise? Researchers from the Weizmann Institute of Sc
...
Written By:
Kara Marker
DEC 18, 2016
Microbiology
To construct new tissue or maintain it in adulthood, cells have to be able to respond to mechanical and molecular cues f
...
Written By:
Carmen Leitch
DEC 18, 2016
Cancer
The newest leukemia research findings suggest that intermittent fasting may literally starve the cancer cells too. The s
...
DEC 17, 2016
Cell & Molecular Biology
Females carry two X chromosomes, and the genes of one of those chromosomes cannot be expressed during development or myr
...
Written By:
Carmen Leitch
DEC 17, 2016
Cancer
If a cancer is caused by the over-activation of proteins that enhance growth, then blocking these enzymes should stunt t
...
DEC 16, 2016
Cell & Molecular Biology
Reporting in Cell, scientists were able to extend the lifespan of mice that carry a genetic mutation that causes prematu
...
Written By:
Carmen Leitch
DEC 13, 2016
Cell & Molecular Biology
Genetic information from genes on DNA is first transcribed into RNA before being made into proteins, the major building
...
Written By:
Carmen Leitch
DEC 13, 2016
Cell & Molecular Biology
Organisms depend on chemical cascades to perform the many life-sustaining functions of cells. Those cascades depend on p
...
Written By:
Carmen Leitch
DEC 12, 2016
Neuroscience
When a patient is diagnosed with Parkinson’s disease (PD) it can seem overwhelming. There is no known cause for PD
...
Written By:
Brenda Kelley Kim
DEC 11, 2016
Videos
In this video from Mayo Clinic, researcher Dr. Shane Shapiro discusses his use of stem cells to treat osteoarthritis pai
...
Written By:
Carmen Leitch
DEC 11, 2016
Cell & Molecular Biology
Cell division is a fundamental process in life. Our cells must continually replicate, and that replication and growth ha
...
Written By:
Carmen Leitch
DEC 09, 2016
Cell & Molecular Biology
Reporting in Nature, researchers have created a way to move molecules between cells; they refer to this new technology a
...
Written By:
Carmen Leitch
DEC 09, 2016
Genetics & Genomics
Combat Obesity by Turning White Fat into Brown Fat
Written By:
Jennifer Ellis
DEC 07, 2016
Chemistry & Physics
Using Photodynamic Therapy to Kill Hard-to-Reach Tumors
Written By:
Jennifer Ellis
DEC 06, 2016
Immunology
Scientists have discovered a cellular switch that can be turned “on” or “off,” which could be vi
...
Written By:
Kara Marker
DEC 05, 2016
Microbiology
Researchers working at the Karolinska Institutet have made a breakthrough that will aid scientists studying biofilms. Th
...
Written By:
Carmen Leitch
DEC 05, 2016
Cell & Molecular Biology
Reporting in Nature Medicine, scientists at St. Jude Children's Research Hospital have determined that a small piece
...
Written By:
Carmen Leitch
DEC 05, 2016
Neuroscience
While there are many health problems related to alcohol use, the stakes are even higher when teenagers drink. The brain
...
Written By:
Brenda Kelley Kim
DEC 05, 2016
Clinical & Molecular DX
LA JOLLA, CA – December 5, 2016 – A common class of drugs for vision loss may actually add to the problem in
...
Written By:
The Scripps Research Institute (TSRI)
DEC 03, 2016
Plants & Animals
Researchers have found a new class of photoreceptor protein known as LITE-1 in invertebrates that could be up to 50 time
...
Written By:
Anthony Bouchard
DEC 02, 2016
Microbiology
Chemically, carbon and silicon are a lot alike; silicon can form bonds with four atoms at once and can create the long,
...
Written By:
Carmen Leitch
DEC 01, 2016
Cell & Molecular Biology
As the brain develops, neurons are created from a special type of neural stem call called radial glia. Researchers at Du
...
Written By:
Carmen Leitch
NOV 30, 2016
Cell & Molecular Biology
The Allen Institute for Cell Science was founded by a contribution by Paul G. Allen, a cofounder of Microsoft, in 2014.
...
Written By:
Carmen Leitch