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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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MAY 17, 2016Genetics & Genomics
Although the genetic code is famous for its double helix and not its quadruple helix, it is known to occur in other form ...Written By: Kara MarkerMAY 16, 2016Microbiology
On May 13, 2016, the White House announced the new National Microbiome Initiative (NMI) for the benefit of people and th ...Written By: Carmen LeitchMAY 11, 2016Cardiology
Newly developed drugs can take 7-10 years to be approved in the United States, and that does not account for the many ye ...Written By: Kara MarkerMAY 11, 2016Immunology
B cells, which are mostly known for antibody production in the face of invading pathogens, provide another function in t ...Written By: Kara MarkerMAY 11, 2016Genetics & Genomics
Scientists from Michigan State University are developing a system to read the genome like normal people read a book. Lik ...Written By: Kara MarkerMAY 10, 2016Cell & Molecular Biology
Since the development of the gene-editing tool CRISPR/Cas9, researchers have found many ways to both improve and vary th ...Written By: Carmen LeitchMAY 06, 2016Cancer
Researchers say a protein biomarker could indicate whether a childhood cancer, neuroblastoma, will relapse. Absence of t ...MAY 05, 2016Cardiology
Dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (DCM) share some qualities in their tissue makeup and in th ...Written By: Kara MarkerMAY 04, 2016Neuroscience
Rupture of small blood vessels in the brain can cause hemorrhagic stroke and brain microbleeds, and finding the fastest ...Written By: Kara MarkerMAY 04, 2016Videos
While no creature can live forever, the jellyfish does have a certain ability to not only stop the aging process, but to ...Written By: Brenda Kelley KimMAY 03, 2016Cancer
Designing effective new drugs, especially drugs to fight cancer, demands that you know as much as you can about the mole ...Written By: The Scripps Research Institute (TSRI)MAY 02, 2016Health & Medicine
For people with a certain gene mutation, metabolizing fat can be much harder for the body to do than it would be for a h ...Written By: Kara MarkerMAY 02, 2016Health & Medicine
It is the antibodies that detect pathogens in order to fight infections and prevent disease, but there is an entire team ...Written By: Kara MarkerMAY 02, 2016Immunology
Findings Could Guide Development of Treatments for Lassa Fever For the first time, scientists at The Scripps Research In ...Written By: The Scripps Research Institute (TSRI)APR 29, 2016Cancer
What do cancer researchers think is the most dangerous part of cancer? Metastasis. This is the ability of cancer to spre ...APR 29, 2016Cell & Molecular Biology
Starving immune cells of key nutrients thwarts their ability to launch an allergic response, according to new resea ...Written By: Futurity (futurity.org)APR 24, 2016Microbiology
Very small fibers made by a bacteria have the unique property of transporting charges at speeds of 1 billion electrons p ...Written By: Futurity (futurity.org)APR 18, 2016Microbiology
Cholera bacteria kill as many as 140,000 people a year. Away from humans, the same bacteria kill neighboring microbes wi ...Written By: Futurity (futurity.org)APR 14, 2016Genetics & Genomics
Chimeric organisms are ones that are made up of cells or tissues from more than one individual, most commonly thought of ...Written By: Kara MarkerAPR 14, 2016Neuroscience
It’s been shown in several research studies that the brains of adults who speak more than one language are more ac ...Written By: Brenda Kelley KimAPR 13, 2016Immunology
A new hope for vaccine development and cancer therapy has been identified, and it is a signaling protein called c-Myc th ...Written By: Kara MarkerAPR 11, 2016Immunology
If you thought finding a needle in a haystack was hard, try maneuvering a T lymphocyte through the “three-dimensio ...Written By: Kara MarkerAPR 11, 2016Cardiology
Antiviral medications used to control HIV and prevent its progression to AIDS improve the health and increase survival f ...Written By: Futurity (futurity.org)APR 11, 2016Health & Medicine
Celiac disease is an autoimmune disorder that is directly related to a misdirected immune response to gluten, a protein ...Written By: Kara Marker
MAY 17, 2016
Genetics & Genomics
Although the genetic code is famous for its double helix and not its quadruple helix, it is known to occur in other form
...
Written By:
Kara Marker
MAY 16, 2016
Microbiology
On May 13, 2016, the White House announced the new National Microbiome Initiative (NMI) for the benefit of people and th
...
Written By:
Carmen Leitch
MAY 11, 2016
Cardiology
Newly developed drugs can take 7-10 years to be approved in the United States, and that does not account for the many ye
...
Written By:
Kara Marker
MAY 11, 2016
Immunology
B cells, which are mostly known for antibody production in the face of invading pathogens, provide another function in t
...
Written By:
Kara Marker
MAY 11, 2016
Genetics & Genomics
Scientists from Michigan State University are developing a system to read the genome like normal people read a book. Lik
...
Written By:
Kara Marker
MAY 10, 2016
Cell & Molecular Biology
Since the development of the gene-editing tool CRISPR/Cas9, researchers have found many ways to both improve and vary th
...
Written By:
Carmen Leitch
MAY 06, 2016
Cancer
Researchers say a protein biomarker could indicate whether a childhood cancer, neuroblastoma, will relapse. Absence of t
...
MAY 05, 2016
Cardiology
Dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (DCM) share some qualities in their tissue makeup and in th
...
Written By:
Kara Marker
MAY 04, 2016
Neuroscience
Rupture of small blood vessels in the brain can cause hemorrhagic stroke and brain microbleeds, and finding the fastest
...
Written By:
Kara Marker
MAY 04, 2016
Videos
While no creature can live forever, the jellyfish does have a certain ability to not only stop the aging process, but to
...
Written By:
Brenda Kelley Kim
MAY 03, 2016
Cancer
Designing effective new drugs, especially drugs to fight cancer, demands that you know as much as you can about the mole
...
Written By:
The Scripps Research Institute (TSRI)
MAY 02, 2016
Health & Medicine
For people with a certain gene mutation, metabolizing fat can be much harder for the body to do than it would be for a h
...
Written By:
Kara Marker
MAY 02, 2016
Health & Medicine
It is the antibodies that detect pathogens in order to fight infections and prevent disease, but there is an entire team
...
Written By:
Kara Marker
MAY 02, 2016
Immunology
Findings Could Guide Development of Treatments for Lassa Fever For the first time, scientists at The Scripps Research In
...
Written By:
The Scripps Research Institute (TSRI)
APR 29, 2016
Cancer
What do cancer researchers think is the most dangerous part of cancer? Metastasis. This is the ability of cancer to spre
...
APR 29, 2016
Cell & Molecular Biology
Starving immune cells of key nutrients thwarts their ability to launch an allergic response, according to new resea
...
Written By:
Futurity (futurity.org)
APR 24, 2016
Microbiology
Very small fibers made by a bacteria have the unique property of transporting charges at speeds of 1 billion electrons p
...
Written By:
Futurity (futurity.org)
APR 18, 2016
Microbiology
Cholera bacteria kill as many as 140,000 people a year. Away from humans, the same bacteria kill neighboring microbes wi
...
Written By:
Futurity (futurity.org)
APR 14, 2016
Genetics & Genomics
Chimeric organisms are ones that are made up of cells or tissues from more than one individual, most commonly thought of
...
Written By:
Kara Marker
APR 14, 2016
Neuroscience
It’s been shown in several research studies that the brains of adults who speak more than one language are more ac
...
Written By:
Brenda Kelley Kim
APR 13, 2016
Immunology
A new hope for vaccine development and cancer therapy has been identified, and it is a signaling protein called c-Myc th
...
Written By:
Kara Marker
APR 11, 2016
Immunology
If you thought finding a needle in a haystack was hard, try maneuvering a T lymphocyte through the “three-dimensio
...
Written By:
Kara Marker
APR 11, 2016
Cardiology
Antiviral medications used to control HIV and prevent its progression to AIDS improve the health and increase survival f
...
Written By:
Futurity (futurity.org)
APR 11, 2016
Health & Medicine
Celiac disease is an autoimmune disorder that is directly related to a misdirected immune response to gluten, a protein
...
Written By:
Kara Marker