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    Chemical Biology

    Chemical Biology: a scientific discipline spanning the fields of chemistry, biology, and physics. It involves the application of chemical techniques, tools, and analyses, and often compounds produced through synthetic chemistry, to the study and manipulation of biological systems. Chemical biologists attempt to use chemical principles to modulate systems to either investigate the underlying biology or create new function. Chemicals - including natural small molecules, such as lipids, carbohydrates and metals, or non-natural probe or drug molecules - are used to gain insight into biological problems at a mechanistic level.

    Webinars

    • NOV 12, 2020 | 9:00 AM
      Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
      Back to Work, School, and Life: Utility of COVID-19 Testing to...
      Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
      Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Thermo Fisher Scientific
      5
      NOV 05, 2020 | 7:30 AM
      Keynote Presentation: The Opioid Crisis: Made in America...Fade in America
      Keynote Presentation: The Opioid Crisis: Made in America...Fade...
      The opioid crisis is a uniquely American challenge. Many factors catalyzed this national nightmare and others continue to fuel it. This presentation delves into some of the major contributor...
      Speaker: Professor Bertha Madras (the Honorable)
      Presented at: Opioid Crisis Virtual Event Series 2020
      1
      NOV 05, 2020 | 7:00 AM
      Stem cell derived exosome production in stirred-tank bioreactors
      Stem cell derived exosome production in stirred-tank bioreactors
      DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
      Speaker: Jorge Escobar , Aurélie Tacheny
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      12
      OCT 29, 2020 | 6:00 AM
      Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
      Single-cell sequencing to investigate epigenetic mechanisms in...
      Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
      Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
      Sponsored By: Illumina, Dolomite Bio
      15
      OCT 08, 2020 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
      Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      33 5
      SEP 30, 2020 | 10:30 AM
      Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
      Straightforward CRISPR knockout: Leveraging predesigned synthetic...
      CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
      Speaker: James Goldmeyer, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Horizon Discovery
      3 1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 17, 2020 | 2:00 PM
      Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
      Keynote Presentation: The formation of an International Collaborative...
      Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
      Speaker: Jacqueline Fabius , Nevan Krogan, PhD
      Presented at: Coronavirus Series
      1
      SEP 16, 2020 | 12:15 PM
      High-resolution HCA-based phenotypic profiling of tumor spheroids and organoids
      High-resolution HCA-based phenotypic profiling of tumor spheroids...
      Image-based high-content screening (HCS) involving cancer cell lines grown in conventional two-dimensional (2D) cell culture, has provided a cornerstone assay for searching new agents to tre...
      Speaker: Meritxell B. Cutrona, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      2
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 08, 2020 | 11:00 PM
      Development of Respiratory Syncytial Virus and Universal Influenza Virus Vaccines Conformationally Stabilized by Targeted Dityrosine Crosslinking
      Development of Respiratory Syncytial Virus and Universal Influenza...
      While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
      Speaker: Mark A. Yondola, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 03, 2020 | 11:00 AM
      Filtered Fume Hoods: Expert insight on improving your lab's green initiative
      Filtered Fume Hoods: Expert insight on improving your lab's green...
      DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
      Speaker: Kasey Fulmer , Kenneth Crooks
      Sponsored By: Labconco
      11
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      AUG 11, 2020 | 10:00 AM
      Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
      Better resolution for CE-SDS analysis of new biopharmaceutical...
      DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
      Speaker: Andras Guttman, PhD
      Sponsored By: SCIEX
      9 4
      AUG 07, 2020 | 10:30 AM
      Part I: Adventures in Chemical Biology and Drug Discovery
      Part I: Adventures in Chemical Biology and Drug Discovery
      In this presentation, I will discuss my experiences leading to my current position as a scientist and team leader, focused on chemical biology and drug discovery in the pharmaceutical indust...
      Speaker: Christopher am Ende, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 07, 2020 | 9:00 AM
      Part II: Adventures in Molecular Recognition
      Part II: Adventures in Molecular Recognition
      In the movie "Moana" the lead character sings the refrain, "There's no telling how far I'll go" before she heads off on the adventure of a lifetime. In this short...
      Speaker: Ming Chen Hammond, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 10:00 AM
      Single Cell Antibody Discovery Using 'Islands of Automation'
      Single Cell Antibody Discovery Using 'Islands of Automation'
      DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
      Speaker: Paul Anderson
      Sponsored By: Beckman Coulter Life Sciences
      16 5
      AUG 06, 2020 | 12:00 AM
      Prevalence and reactivity of fused-rubredoxin AlkBs
      Prevalence and reactivity of fused-rubredoxin AlkBs
      Over 100 distinct alkane monooxygenase (AlkB) enzymes containing a covalently bound, or fused, rubredoxin domain were identified and analyzed using bioinformatic techniques. One such protein...
      Speaker: Shoshana Williams
      Presented at: 2020 Beckman Symposium
      1
      JUN 18, 2020 | 8:00 AM
      Cracking Cellular Metabolism
      Cracking Cellular Metabolism
      Are you interested in Novel Sample Prep and gaining Powerful Insights with Discovery-based LC/MS Workflows? In this session, we will demonstrate a complete untargeted metabolomics workflow f...
      Speaker: Mark Sartain, PhD , Genevieve Van de Bittner, PhD
      Presented at: Agilent's Virtual Mass Spectacular!
      2
      MAY 20, 2020 | 9:00 AM
      Keynote Presentation: Quantitative biology with droplet microfluidics
      Keynote Presentation: Quantitative biology with droplet microfluidics
      Many questions at the forefront of biology depend on the interactions of millions of single cells. My lab develops technologies for studying large numbers of single cells. In this talk, I wi...
      Speaker: Adam Abate, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 06, 2020 | 1:00 PM
      Estimating the age of biological evidence recovered from a crime scene by assessing RNA degradation in the sample
      Estimating the age of biological evidence recovered from a crime...
      The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
      Speaker: Robert W. Allen, PhD
      Presented at: Forensic Sciences Virtual Event Series 2020
      5
      MAY 06, 2020 | 9:00 AM
      Keynote Presentation: Pattern Evidence Reconstruction
      Keynote Presentation: Pattern Evidence Reconstruction
      Crime scene investigation is more than just processing or documentation of crime scenes, nor is it just the collection or packaging of physical evidence. It is the first step and the most cr...
      Speaker: Henry C. Lee, PhD
      Presented at: Forensic Sciences Virtual Event Series 2020
      2
      MAY 06, 2020 | 7:30 AM
      Keynote Presentation: Complexities of characterizing mineral particle toxicity at the pulmonary interface
      Keynote Presentation: Complexities of characterizing mineral particle...
      The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...
      Speaker: Christopher Weis, PhD, DABT
      Presented at: Forensic Sciences Virtual Event Series 2020
      1
      MAY 06, 2020 | 12:00 AM
      New Relevance of Hydroxychloroquine and Chloroquine in Forensic Toxicology
      New Relevance of Hydroxychloroquine and Chloroquine in Forensic...
      Hydroxychloroquine and chloroquine are long-standing antimalarial drugs recently brought into the spotlight as potential treatments for the pandemic-causing coronavirus (SARS-CoV-2). Notable...
      Speaker: Wendy Adams, PhD, F-ABFT
      Presented at: Forensic Sciences Virtual Event Series 2020
      2
    NOV 12, 2020 | 9:00 AM
    Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
    Back to Work, School, and Life: Utility of COVID-19 Testing to...
    Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
    Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Thermo Fisher Scientific
    5
    NOV 05, 2020 | 7:30 AM
    Keynote Presentation: The Opioid Crisis: Made in America...Fade in America
    Keynote Presentation: The Opioid Crisis: Made in America...Fade...
    The opioid crisis is a uniquely American challenge. Many factors catalyzed this national nightmare and others continue to fuel it. This presentation delves into some of the major contributor...
    Speaker: Professor Bertha Madras (the Honorable)
    Presented at: Opioid Crisis Virtual Event Series 2020
    1
    NOV 05, 2020 | 7:00 AM
    Stem cell derived exosome production in stirred-tank bioreactors
    Stem cell derived exosome production in stirred-tank bioreactors
    DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
    Speaker: Jorge Escobar , Aurélie Tacheny
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    12
    OCT 29, 2020 | 6:00 AM
    Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
    Single-cell sequencing to investigate epigenetic mechanisms in...
    Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
    Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
    Sponsored By: Illumina, Dolomite Bio
    15
    OCT 08, 2020 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    33 5
     
     
  • SEP 30, 2020 | 10:30 AM
    Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
    Straightforward CRISPR knockout: Leveraging predesigned synthetic...
    CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
    Speaker: James Goldmeyer, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Horizon Discovery
    3 1
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 17, 2020 | 2:00 PM
    Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
    Keynote Presentation: The formation of an International Collaborative...
    Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
    Speaker: Jacqueline Fabius , Nevan Krogan, PhD
    Presented at: Coronavirus Series
    1
    SEP 16, 2020 | 12:15 PM
    High-resolution HCA-based phenotypic profiling of tumor spheroids and organoids
    High-resolution HCA-based phenotypic profiling of tumor spheroids...
    Image-based high-content screening (HCS) involving cancer cell lines grown in conventional two-dimensional (2D) cell culture, has provided a cornerstone assay for searching new agents to tre...
    Speaker: Meritxell B. Cutrona, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    2
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
     
     
  • SEP 08, 2020 | 11:00 PM
    Development of Respiratory Syncytial Virus and Universal Influenza Virus Vaccines Conformationally Stabilized by Targeted Dityrosine Crosslinking
    Development of Respiratory Syncytial Virus and Universal Influenza...
    While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
    Speaker: Mark A. Yondola, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 03, 2020 | 11:00 AM
    Filtered Fume Hoods: Expert insight on improving your lab's green initiative
    Filtered Fume Hoods: Expert insight on improving your lab's green...
    DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
    Speaker: Kasey Fulmer , Kenneth Crooks
    Sponsored By: Labconco
    11
    AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
    AUG 11, 2020 | 10:00 AM
    Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
    Better resolution for CE-SDS analysis of new biopharmaceutical...
    DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
    Speaker: Andras Guttman, PhD
    Sponsored By: SCIEX
    9 4
    AUG 07, 2020 | 10:30 AM
    Part I: Adventures in Chemical Biology and Drug Discovery
    Part I: Adventures in Chemical Biology and Drug Discovery
    In this presentation, I will discuss my experiences leading to my current position as a scientist and team leader, focused on chemical biology and drug discovery in the pharmaceutical indust...
    Speaker: Christopher am Ende, PhD
    Presented at: 2020 Beckman Symposium
    1
     
     
  • AUG 07, 2020 | 9:00 AM
    Part II: Adventures in Molecular Recognition
    Part II: Adventures in Molecular Recognition
    In the movie "Moana" the lead character sings the refrain, "There's no telling how far I'll go" before she heads off on the adventure of a lifetime. In this short...
    Speaker: Ming Chen Hammond, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 10:00 AM
    Single Cell Antibody Discovery Using 'Islands of Automation'
    Single Cell Antibody Discovery Using 'Islands of Automation'
    DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
    Speaker: Paul Anderson
    Sponsored By: Beckman Coulter Life Sciences
    16 5
    AUG 06, 2020 | 12:00 AM
    Prevalence and reactivity of fused-rubredoxin AlkBs
    Prevalence and reactivity of fused-rubredoxin AlkBs
    Over 100 distinct alkane monooxygenase (AlkB) enzymes containing a covalently bound, or fused, rubredoxin domain were identified and analyzed using bioinformatic techniques. One such protein...
    Speaker: Shoshana Williams
    Presented at: 2020 Beckman Symposium
    1
    JUN 18, 2020 | 8:00 AM
    Cracking Cellular Metabolism
    Cracking Cellular Metabolism
    Are you interested in Novel Sample Prep and gaining Powerful Insights with Discovery-based LC/MS Workflows? In this session, we will demonstrate a complete untargeted metabolomics workflow f...
    Speaker: Mark Sartain, PhD , Genevieve Van de Bittner, PhD
    Presented at: Agilent's Virtual Mass Spectacular!
    2
    MAY 20, 2020 | 9:00 AM
    Keynote Presentation: Quantitative biology with droplet microfluidics
    Keynote Presentation: Quantitative biology with droplet microfluidics
    Many questions at the forefront of biology depend on the interactions of millions of single cells. My lab develops technologies for studying large numbers of single cells. In this talk, I wi...
    Speaker: Adam Abate, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
     
     
  • MAY 06, 2020 | 1:00 PM
    Estimating the age of biological evidence recovered from a crime scene by assessing RNA degradation in the sample
    Estimating the age of biological evidence recovered from a crime...
    The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
    Speaker: Robert W. Allen, PhD
    Presented at: Forensic Sciences Virtual Event Series 2020
    5
    MAY 06, 2020 | 9:00 AM
    Keynote Presentation: Pattern Evidence Reconstruction
    Keynote Presentation: Pattern Evidence Reconstruction
    Crime scene investigation is more than just processing or documentation of crime scenes, nor is it just the collection or packaging of physical evidence. It is the first step and the most cr...
    Speaker: Henry C. Lee, PhD
    Presented at: Forensic Sciences Virtual Event Series 2020
    2
    MAY 06, 2020 | 7:30 AM
    Keynote Presentation: Complexities of characterizing mineral particle toxicity at the pulmonary interface
    Keynote Presentation: Complexities of characterizing mineral particle...
    The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...
    Speaker: Christopher Weis, PhD, DABT
    Presented at: Forensic Sciences Virtual Event Series 2020
    1
    MAY 06, 2020 | 12:00 AM
    New Relevance of Hydroxychloroquine and Chloroquine in Forensic Toxicology
    New Relevance of Hydroxychloroquine and Chloroquine in Forensic...
    Hydroxychloroquine and chloroquine are long-standing antimalarial drugs recently brought into the spotlight as potential treatments for the pandemic-causing coronavirus (SARS-CoV-2). Notable...
    Speaker: Wendy Adams, PhD, F-ABFT
    Presented at: Forensic Sciences Virtual Event Series 2020
    2
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