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Complex Disease
Caused by genetic, environmental, and lifestyle factors, complex diseases such as asthma, diabetes, epilepsy, hypertension, manic depression, schizophrenia, and others, are often difficult to treat. Disorders that are commonly referenced as "running in the family" can be classified as complex diseases.
MAY 13, 2015 | 5:00 AM
The implementation of Next Generation Sequencing (NGS) technology in the clinical laboratory has allowed for large-scale panel testing of many genes simultaneously at a reduced cost and turn-...
APR 07, 2015 | 8:30 AM
Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
MAR 18, 2015 | 1:30 PM
At the cellular and molecular levels of operation, neurons and their circuits achieve brain functions by chemical signals, in which the principle agents, neurotransmitters convey the signal f...
OCT 30, 2014 | 3:00 PM
Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
OCT 29, 2014 | 3:00 PM
Illumina next-generation sequencing (NGS) and microarray technologies are revolutionizing cancer research, enabling cancer variant discovery and detection and molecular monitoring. Join u...
OCT 29, 2014 | 12:00 PM
Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
OCT 29, 2014 | 10:30 AM
The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
OCT 29, 2014 | 9:00 AM
Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
OCT 24, 2014 | 12:00 PM
  Influenza is a major clinical and public health issue. Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
AUG 21, 2014 | 12:45 PM
When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
AUG 21, 2014 | 11:30 AM
The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
AUG 21, 2014 | 9:45 AM
In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
AUG 21, 2014 | 8:45 AM
With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
AUG 20, 2014 | 11:45 AM
The unanimous Supreme Court ruling of 2013 regarding gene patents made competition for BRCA1 and BRCA2 testing a reality. Within hours of the decision multiple labs began offering more compre...
AUG 20, 2014 | 11:30 AM
High-throughput short-read DNA sequencing has revolutionized our ability to measure genetic variation in the form of single-nucleotide polymorphisms (SNPs) in human genomes. However, ~75% of...
AUG 20, 2014 | 8:45 AM
The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
AUG 20, 2014 | 8:00 AM
Structural variants (SVs), defined as the deletion, duplication, insertion, inversion or translocation of genomic regions, are both a major source of genetic diversity in human populations an...
