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    Computational Model

    Computational Model: is a mathematical model in computational science that requires extensive computational resources to study the behavior of a complex system by computer simulation. The system under study is often a complex nonlinear system for which simple, intuitive analytical solutions are not readily available.

    Webinars

    • DEC 07, 2016 | 9:00 AM
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
      Speaker: Edgar Jacoby, Ph.D.
      Sponsored By: DiscoverX, DiscoverX
      4
      SEP 20, 2016 | 7:00 AM
      Advanced Analysis of Complex Cell Models with the New Operetta CLS HCA System
      Advanced Analysis of Complex Cell Models with the New Operetta...
      DATE: September 20th, 2016TIME:  7:00AM PST, 10:00AM ETThere is a growing trend towards developing in vitro cell models that recapitulate the in vivo environment in basic research,...
      Speaker: Jacob Tesdorpf, PhD , Joe Trask
      Sponsored By: Revvity
      25
      AUG 24, 2016 | 8:00 AM
      Beyond Bone: Emerging Applications in Preclinical microCT Imaging
      Beyond Bone: Emerging Applications in Preclinical microCT Imaging
      DATE: August 24th 2016TIME:  8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
      Speaker: Gael Rochefort, PhD , Chris Damoci
      Sponsored By: Revvity
      32
      JUL 26, 2016 | 7:30 AM
      Automated assays for protein engineering: in vitro and in vivo
      Automated assays for protein engineering: in vitro and in vivo
      Enzyme engineering is a powerful technology now widely used in laboratories around the world. The goal is to obtain improved proteins that will serve as better biocatalysts, biosensors or as ...
      Speaker: Daniela Quaglia, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      10 2
      MAY 12, 2016 | 3:00 PM
      Using big data to interpret genomes for diagnostics, therapeutics, and precision medicine
      Using big data to interpret genomes for diagnostics, therapeutics,...
      Millions of individuals have been sequenced or genotyped and linked with medical records, providing an exciting opportunity for therapeutic target discovery. My lab has been using a resilienc...
      Speaker: Rong Chen, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 12, 2016 | 10:30 AM
      Antha: An Operating System for Seamlessly Linking Experimental Design and Lab Automation
      Antha: An Operating System for Seamlessly Linking Experimental...
      Working with biology currently takes too long, costs too much, and fails too often. At the core of this is the complexity of the systems we are trying to understand, compounded by a lack of r...
      Speaker: Sean Ward
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 12, 2016 | 10:30 AM
      C.E. CREDITS
      Big data integration - Inferring and using individual patient network models
      Big data integration - Inferring and using individual patient...
      The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
      Speaker: Marieke Kuijjer, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      5
      MAY 11, 2016 | 12:00 PM
      Assembly and Analysis of Non-model Organism Transcriptomes Using DNASTAR Software
      Assembly and Analysis of Non-model Organism Transcriptomes Using...
      DNASTAR offers an integrated suite of software for accurate assembly and analysis of sequence data from all major next-generation sequencing platforms supporting key workflows including de no...
      Speaker: Matthew Keyser, MS
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 11, 2016 | 10:30 AM
      C.E. CREDITS
      Challenges and Opportunities Building IT capabilities to support Large Scale Omics Projects in a Health System
      Challenges and Opportunities Building IT capabilities to support...
      We are at a time where traditionally risk-adverse health care systems and their IT architecture are confronted with the deluge of data at a massive scale and tremendous variability. In many H...
      Speaker: Aaron Black
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAR 16, 2016 | 1:30 PM
      Impulse control disorders (behavioural addictions): insights from dopaminergic medication-related behaviours in Parkinson's disease
      Impulse control disorders (behavioural addictions): insights from...
      Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences.  ICDs can also commonly occur with exposure...
      Speaker: Valerie Voon, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      2 1
      FEB 24, 2016 | 10:00 AM
      Harnessing the Power of Healthcare Data with Causal Machine Learning to drive Personalized and Effective Treatment Interventions
      Harnessing the Power of Healthcare Data with Causal Machine Learning...
      Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
      Speaker: Iya Khalil, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 8:00 AM
      Keynote Presentation - Integrating the digital universe of data with consumer-driven mobile apps and large-scale panomics data to better understand, treat, and prevent disease
      Keynote Presentation - Integrating the digital universe of data...
      One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
      Speaker: Eric Schadt, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 03, 2016 | 7:30 AM
      Keynote: Vibration, Noise & Ultrasonic Noise From Vivarium and Lab Equipment as Rapidly Growing Confounds in Animal Research
      Keynote: Vibration, Noise & Ultrasonic Noise From Vivarium and...
      Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
      Speaker: Jeremy Turner, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      3
      FEB 02, 2016 | 9:00 AM
      Arrays or RNA-Seq? Choosing the right tool for the job
      Arrays or RNA-Seq? Choosing the right tool for the job
      DATE: February 2nd, 2016 TIME:  9am pacific time, 12pm eastern time What is the most appropriate technology to empower your research?   Next generation sequencing (NGS) for RN...
      Speaker: Sridar Chittur, PhD, MBA , Yesim Gökmen-Polar, PhD
      Sponsored By: Affymetrix, Affymetrix
      11 3
      SEP 16, 2015 | 7:00 AM
      Open Science for Rare and Neglected Diseases
      Open Science for Rare and Neglected Diseases
      As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
      Speaker: Sean Ekins
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      4
      MAY 13, 2015 | 12:00 PM
      What can we learn from large gene expression data sets?
      What can we learn from large gene expression data sets?
      The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
      Speaker: Jeremy A Miller, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      2
      MAY 13, 2015 | 10:30 AM
      Statistical methods for bulk and single-cell RNA-seq experiments
      Statistical methods for bulk and single-cell RNA-seq experiments
      I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
      Speaker: Christina Kendziorski, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4 1
      MAY 13, 2015 | 7:30 AM
      Keynote: Big Data in Health Care and Biomedical Research
      Keynote: Big Data in Health Care and Biomedical Research
      Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      0 1
      APR 16, 2015 | 8:00 AM
      Advances in Sedimentation Analysis
      Advances in Sedimentation Analysis
      In recent years, sophisticated new methods for sedimentation data analysis have opened up new avenues for leveraging AUC technology in a wide range of technology sectors, including life scien...
      Speaker: Borries Demeler, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      12 1
      FEB 05, 2015 | 9:00 AM
      C.E. CREDITS
      Keynote: Advances in Perioperative Care -Promoting good animal welfare and good science
      Keynote: Advances in Perioperative Care -Promoting good animal...
      Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
      Speaker: Paul Flecknell, MA, VetMB, PhD, DLAS, DECVAA, DECLAM, (Hon)DACLAM, (Hon) FRCVS, Dr.hc
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      6
      OCT 30, 2014 | 3:00 PM
      Probing cancer metabolism using isotope tracers to identify therapeutic targets
      Probing cancer metabolism using isotope tracers to identify therapeutic...
      Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
      Speaker: Christian Metallo, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 12:00 PM
      Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
      Breast-Predict: Leveraging the Power of Systems Medicine Towards...
      Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
      Speaker: William M. Gallagher, BSc PhD CBiol MSB
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 10:30 AM
      Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
      Learning from the Pointillists - Using Big Data Approaches to...
      The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      SEP 24, 2014 | 1:00 PM
      Evolve or die a darwinian-like innovation process for technology
      Evolve or die a darwinian-like innovation process for technology
      At Biogen Idec, we have implemented a 3 part innovation operating model which includes innovation mentoring, agile experimentation and transition of experiments into pilots. In this presenta...
      Speaker: Martin Leach
      Presented at: Advances in Drug Discovery and Development
      0
    DEC 07, 2016 | 9:00 AM
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
    Speaker: Edgar Jacoby, Ph.D.
    Sponsored By: DiscoverX, DiscoverX
    4
    SEP 20, 2016 | 7:00 AM
    Advanced Analysis of Complex Cell Models with the New Operetta CLS HCA System
    Advanced Analysis of Complex Cell Models with the New Operetta...
    DATE: September 20th, 2016TIME:  7:00AM PST, 10:00AM ETThere is a growing trend towards developing in vitro cell models that recapitulate the in vivo environment in basic research,...
    Speaker: Jacob Tesdorpf, PhD , Joe Trask
    Sponsored By: Revvity
    25
    AUG 24, 2016 | 8:00 AM
    Beyond Bone: Emerging Applications in Preclinical microCT Imaging
    Beyond Bone: Emerging Applications in Preclinical microCT Imaging
    DATE: August 24th 2016TIME:  8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
    Speaker: Gael Rochefort, PhD , Chris Damoci
    Sponsored By: Revvity
    32
    JUL 26, 2016 | 7:30 AM
    Automated assays for protein engineering: in vitro and in vivo
    Automated assays for protein engineering: in vitro and in vivo
    Enzyme engineering is a powerful technology now widely used in laboratories around the world. The goal is to obtain improved proteins that will serve as better biocatalysts, biosensors or as ...
    Speaker: Daniela Quaglia, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    10 2
    MAY 12, 2016 | 3:00 PM
    Using big data to interpret genomes for diagnostics, therapeutics, and precision medicine
    Using big data to interpret genomes for diagnostics, therapeutics,...
    Millions of individuals have been sequenced or genotyped and linked with medical records, providing an exciting opportunity for therapeutic target discovery. My lab has been using a resilienc...
    Speaker: Rong Chen, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
     
     
  • MAY 12, 2016 | 10:30 AM
    Antha: An Operating System for Seamlessly Linking Experimental Design and Lab Automation
    Antha: An Operating System for Seamlessly Linking Experimental...
    Working with biology currently takes too long, costs too much, and fails too often. At the core of this is the complexity of the systems we are trying to understand, compounded by a lack of r...
    Speaker: Sean Ward
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 12, 2016 | 10:30 AM
    C.E. CREDITS
    Big data integration - Inferring and using individual patient network models
    Big data integration - Inferring and using individual patient...
    The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
    Speaker: Marieke Kuijjer, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    5
    MAY 11, 2016 | 12:00 PM
    Assembly and Analysis of Non-model Organism Transcriptomes Using DNASTAR Software
    Assembly and Analysis of Non-model Organism Transcriptomes Using...
    DNASTAR offers an integrated suite of software for accurate assembly and analysis of sequence data from all major next-generation sequencing platforms supporting key workflows including de no...
    Speaker: Matthew Keyser, MS
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 11, 2016 | 10:30 AM
    C.E. CREDITS
    Challenges and Opportunities Building IT capabilities to support Large Scale Omics Projects in a Health System
    Challenges and Opportunities Building IT capabilities to support...
    We are at a time where traditionally risk-adverse health care systems and their IT architecture are confronted with the deluge of data at a massive scale and tremendous variability. In many H...
    Speaker: Aaron Black
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAR 16, 2016 | 1:30 PM
    Impulse control disorders (behavioural addictions): insights from dopaminergic medication-related behaviours in Parkinson's disease
    Impulse control disorders (behavioural addictions): insights from...
    Impulse control disorders (ICDs), also known as behavioural addictions, are common in the general population and can have marked consequences.  ICDs can also commonly occur with exposure...
    Speaker: Valerie Voon, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    2 1
     
     
  • FEB 24, 2016 | 10:00 AM
    Harnessing the Power of Healthcare Data with Causal Machine Learning to drive Personalized and Effective Treatment Interventions
    Harnessing the Power of Healthcare Data with Causal Machine Learning...
    Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
    Speaker: Iya Khalil, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 8:00 AM
    Keynote Presentation - Integrating the digital universe of data with consumer-driven mobile apps and large-scale panomics data to better understand, treat, and prevent disease
    Keynote Presentation - Integrating the digital universe of data...
    One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
    Speaker: Eric Schadt, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 03, 2016 | 7:30 AM
    Keynote: Vibration, Noise & Ultrasonic Noise From Vivarium and Lab Equipment as Rapidly Growing Confounds in Animal Research
    Keynote: Vibration, Noise & Ultrasonic Noise From Vivarium and...
    Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
    Speaker: Jeremy Turner, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    3
    FEB 02, 2016 | 9:00 AM
    Arrays or RNA-Seq? Choosing the right tool for the job
    Arrays or RNA-Seq? Choosing the right tool for the job
    DATE: February 2nd, 2016 TIME:  9am pacific time, 12pm eastern time What is the most appropriate technology to empower your research?   Next generation sequencing (NGS) for RN...
    Speaker: Sridar Chittur, PhD, MBA , Yesim Gökmen-Polar, PhD
    Sponsored By: Affymetrix, Affymetrix
    11 3
    SEP 16, 2015 | 7:00 AM
    Open Science for Rare and Neglected Diseases
    Open Science for Rare and Neglected Diseases
    As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
    Speaker: Sean Ekins
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    4
     
     
  • MAY 13, 2015 | 12:00 PM
    What can we learn from large gene expression data sets?
    What can we learn from large gene expression data sets?
    The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
    Speaker: Jeremy A Miller, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    2
    MAY 13, 2015 | 10:30 AM
    Statistical methods for bulk and single-cell RNA-seq experiments
    Statistical methods for bulk and single-cell RNA-seq experiments
    I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
    Speaker: Christina Kendziorski, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4 1
    MAY 13, 2015 | 7:30 AM
    Keynote: Big Data in Health Care and Biomedical Research
    Keynote: Big Data in Health Care and Biomedical Research
    Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    0 1
    APR 16, 2015 | 8:00 AM
    Advances in Sedimentation Analysis
    Advances in Sedimentation Analysis
    In recent years, sophisticated new methods for sedimentation data analysis have opened up new avenues for leveraging AUC technology in a wide range of technology sectors, including life scien...
    Speaker: Borries Demeler, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    12 1
    FEB 05, 2015 | 9:00 AM
    C.E. CREDITS
    Keynote: Advances in Perioperative Care -Promoting good animal welfare and good science
    Keynote: Advances in Perioperative Care -Promoting good animal...
    Recent advances in anesthesia, monitoring, pain assessment and analgesia provide many opportunities for improving the quality of our in vivo scientific data, and promoting high standards of a...
    Speaker: Paul Flecknell, MA, VetMB, PhD, DLAS, DECVAA, DECLAM, (Hon)DACLAM, (Hon) FRCVS, Dr.hc
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    6
     
     
  • OCT 30, 2014 | 3:00 PM
    Probing cancer metabolism using isotope tracers to identify therapeutic targets
    Probing cancer metabolism using isotope tracers to identify therapeutic...
    Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
    Speaker: Christian Metallo, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 12:00 PM
    Breast-Predict: Leveraging the Power of Systems Medicine Towards Personalized Cancer Therapy
    Breast-Predict: Leveraging the Power of Systems Medicine Towards...
    Although the incidence of breast cancer is steadily increasing, mortality rates are decreasing. This means that the majority of women with breast cancer now survive, making it even more impor...
    Speaker: William M. Gallagher, BSc PhD CBiol MSB
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 29, 2014 | 10:30 AM
    Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
    Learning from the Pointillists - Using Big Data Approaches to...
    The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    SEP 24, 2014 | 1:00 PM
    Evolve or die a darwinian-like innovation process for technology
    Evolve or die a darwinian-like innovation process for technology
    At Biogen Idec, we have implemented a 3 part innovation operating model which includes innovation mentoring, agile experimentation and transition of experiments into pilots. In this presenta...
    Speaker: Martin Leach
    Presented at: Advances in Drug Discovery and Development
    0
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