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    CRISPR-Cas9

    CRISPR-Cas9: Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system,and form the basis of a genome editing technology known as CRISPR/Cas9 that allows permanent modification of genes within organisms. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. It is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.

    Trending News

    • MAR 03, 2020
      Cell & Molecular Biology
      New CRISPR-HOT Technique Can Color Cells and Genes
      New CRISPR-HOT Technique Can Color Cells and Genes
      Since the CRISPR/Cas9 editing tool was developed several years ago, many scientists have modified and improved it for di ...
      Written By: Carmen Leitch
      1
      FEB 05, 2020
      Clinical & Molecular DX
      A new CRISPR-based test for coronavirus infections
      A new CRISPR-based test for coronavirus infections
      A surge in infections has caused panic surrounding the coronavirus (2019-nCoV) outbreak to reach a fever pitch. Despite ...
      Written By: Tara Fernandes
      1
      JAN 28, 2020
      Genetics & Genomics
      Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
      Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
      Because of a genetic mutation, people that have Duchenne muscular dystrophy lack functional copies of a protein called d ...
      Written By: Carmen Leitch
      1
      DEC 25, 2019
      Genetics & Genomics
      Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
      Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
      A team of researchers from New York’s Cold Spring Harbor Laboratory have created a new strain of tomatoes that can ...
      Written By: Annie Lennon
      2
      DEC 23, 2019
      Genetics & Genomics
      A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
      A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
      Muscles have a supply of restorative stem cells called satellite cells, and now they have identified a new type.
      Written By: Carmen Leitch
      1
      DEC 20, 2019
      Genetics & Genomics
      Can We Cure Down's Syndrome with Gene Therapy?
      Can We Cure Down's Syndrome with Gene Therapy?
      Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome ...
      Written By: Annie Lennon
      1
      DEC 15, 2019
      Genetics & Genomics
      Making T-Cell Therapy Even More Effective
      Making T-Cell Therapy Even More Effective
      Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy.
      Written By: Carmen Leitch
      1
      DEC 10, 2019
      Genetics & Genomics
      The Fallout From the CRISPR Infant Experiment Continues
      The Fallout From the CRISPR Infant Experiment Continues
      Last year, Chinese scientist He Jiankui caused tremendous controversy in the scientific world by conducting a gene-editi ...
      Written By: Carmen Leitch
      1
      DEC 07, 2019
      Genetics & Genomics
      New Tool Rapidly Detects Unintended Gene Changes from CRISPR
      New Tool Rapidly Detects Unintended Gene Changes from CRISPR
      CRISPR is one of the most promising technologies under development to treat deadly inherited conditions such as cystic f ...
      Written By: Annie Lennon
      1
      DEC 01, 2019
      Cell & Molecular Biology
      Using CRISPR/Cas9 to Modify Chemical Reactions in Cells
      Using CRISPR/Cas9 to Modify Chemical Reactions in Cells
      Since the CRISPR gene editor was created, researchers around the world have tweaked and refined the tool to use it in a ...
      Written By: Carmen Leitch
      1
      NOV 03, 2019
      Genetics & Genomics
      Can CRISPR Replace Antibiotics?
      Can CRISPR Replace Antibiotics?
      Antibiotic-resistant infections claim around 700,000 lives per year, with estimates saying that this number could swell ...
      Written By: Annie Lennon
      1 1
      OCT 30, 2019
      Genetics & Genomics
      Disruptions in Mitochondrial Quality Control Can Cause Heart Disease
      Disruptions in Mitochondrial Quality Control Can Cause Heart Disease
      Researchers have learned why mutations in the ANT gene lead to heart problems.
      Written By: Carmen Leitch
      2
      OCT 22, 2019
      Cell & Molecular Biology
      Scientists Create a New Version of CRISPR - Prime Editing
      Scientists Create a New Version of CRISPR - Prime Editing
      A new technique enables researchers to target and modify one base pair out of billions, and could correct disease-causin ...
      Written By: Carmen Leitch
      2
      OCT 10, 2019
      Genetics & Genomics
      Gene-Editing Breakthrough for Cervical Cancer
      Gene-Editing Breakthrough for Cervical Cancer
      Researchers at the The Menzies Health Institute Queensland have found a way to use gene therapy CRISPR-Cas9 to treat cer ...
      Written By: Annie Lennon
      2
      OCT 06, 2019
      Microbiology
      Using CRISPR to Alter or Kill Bacteria
      Using CRISPR to Alter or Kill Bacteria
      In recent years, the gene editing tool CRISPR/Cas9 has been applied to a wide variety of different organisms, and now, b ...
      Written By: Carmen Leitch
      1
      OCT 03, 2019
      Genetics & Genomics
      A More Precise Version of CRISPR/Cas9 is Created
      A More Precise Version of CRISPR/Cas9 is Created
      A more accurate version of Cas9 has been created, reducing the number of off-target effects. It may be better suited for ...
      Written By: Carmen Leitch
      1
      SEP 23, 2019
      Cell & Molecular Biology
      Using CRISPR to Track and Image Genome Editing in Real Time
      Using CRISPR to Track and Image Genome Editing in Real Time
      A team of scientists use fluorescently labeled proteins and CRISPR technology to image DNA transcription and chromosomal ...
      Written By: Carly Boyd
      1
      SEP 20, 2019
      Neuroscience
      Can CRISPR Technology Treat Alzheimer's?
      Can CRISPR Technology Treat Alzheimer's?
      New drugs that seek to treat Alzheimer’s disease (AD) have a 99.6% failure rate. This makes it the only disease in ...
      Written By: Annie Lennon
      1
      SEP 11, 2019
      Genetics & Genomics
      Rearranging Whole Chromosomes with CRISPR
      Rearranging Whole Chromosomes with CRISPR
      CRISPR/Cas9 was developed as a gene-editing tool and now it's going beyond small, targeted changes in the genome.
      Written By: Carmen Leitch
      2
      AUG 30, 2019
      Health & Medicine
      Mutant sheep bred to help scientists understand rare child brain disease
      Mutant sheep bred to help scientists understand rare child brain disease
      Scientists at Edinburgh University’s Roslin Institute have created a flock of sheep that carry the gene for a heri ...
      Written By: Dr. Nina Lichtenberg
      2
      AUG 27, 2019
      Genetics & Genomics
      Using CRISPR to Edit the DNA Carried by Human Sperm
      Using CRISPR to Edit the DNA Carried by Human Sperm
      Efforts to edit the human genome are rolling forward, despite a call for a moratorium on heritable edits.
      Written By: Carmen Leitch
      1
      AUG 26, 2019
      Genetics & Genomics
      New Gene Editing Technology to Combat Hereditary Diseases
      New Gene Editing Technology to Combat Hereditary Diseases
      Until recently, many types of gene-editing methods were unable to target critical parts of DNA. Now however, researchers ...
      Written By: Annie Lennon
      2
      AUG 23, 2019
      Genetics & Genomics
      Altering Dozens or Hundreds of Genes at Once
      Altering Dozens or Hundreds of Genes at Once
      Since it was developed, the CRISPR gene editing system has been refined and advanced.
      Written By: Carmen Leitch
      3
      AUG 18, 2019
      Genetics & Genomics
      Modified CRISPR Can Manipulate Gene Activity in Neurons
      Modified CRISPR Can Manipulate Gene Activity in Neurons
      There are challenges to working with nerve cells in the lab, which can create research bottlenecks in the study of neuro ...
      Written By: Carmen Leitch
      1
    MAR 03, 2020
    Cell & Molecular Biology
    New CRISPR-HOT Technique Can Color Cells and Genes
    New CRISPR-HOT Technique Can Color Cells and Genes
    Since the CRISPR/Cas9 editing tool was developed several years ago, many scientists have modified and improved it for di ...
    Written By: Carmen Leitch
    1
    FEB 05, 2020
    Clinical & Molecular DX
    A new CRISPR-based test for coronavirus infections
    A new CRISPR-based test for coronavirus infections
    A surge in infections has caused panic surrounding the coronavirus (2019-nCoV) outbreak to reach a fever pitch. Despite ...
    Written By: Tara Fernandes
    1
    JAN 28, 2020
    Genetics & Genomics
    Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
    Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
    Because of a genetic mutation, people that have Duchenne muscular dystrophy lack functional copies of a protein called d ...
    Written By: Carmen Leitch
    1
    DEC 25, 2019
    Genetics & Genomics
    Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
    Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
    A team of researchers from New York’s Cold Spring Harbor Laboratory have created a new strain of tomatoes that can ...
    Written By: Annie Lennon
    2
    DEC 23, 2019
    Genetics & Genomics
    A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
    A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
    Muscles have a supply of restorative stem cells called satellite cells, and now they have identified a new type.
    Written By: Carmen Leitch
    1
     
     
  • DEC 20, 2019
    Genetics & Genomics
    Can We Cure Down's Syndrome with Gene Therapy?
    Can We Cure Down's Syndrome with Gene Therapy?
    Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome ...
    Written By: Annie Lennon
    1
    DEC 15, 2019
    Genetics & Genomics
    Making T-Cell Therapy Even More Effective
    Making T-Cell Therapy Even More Effective
    Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy.
    Written By: Carmen Leitch
    1
    DEC 10, 2019
    Genetics & Genomics
    The Fallout From the CRISPR Infant Experiment Continues
    The Fallout From the CRISPR Infant Experiment Continues
    Last year, Chinese scientist He Jiankui caused tremendous controversy in the scientific world by conducting a gene-editi ...
    Written By: Carmen Leitch
    1
    DEC 07, 2019
    Genetics & Genomics
    New Tool Rapidly Detects Unintended Gene Changes from CRISPR
    New Tool Rapidly Detects Unintended Gene Changes from CRISPR
    CRISPR is one of the most promising technologies under development to treat deadly inherited conditions such as cystic f ...
    Written By: Annie Lennon
    1
    DEC 01, 2019
    Cell & Molecular Biology
    Using CRISPR/Cas9 to Modify Chemical Reactions in Cells
    Using CRISPR/Cas9 to Modify Chemical Reactions in Cells
    Since the CRISPR gene editor was created, researchers around the world have tweaked and refined the tool to use it in a ...
    Written By: Carmen Leitch
    1
     
     
  • NOV 03, 2019
    Genetics & Genomics
    Can CRISPR Replace Antibiotics?
    Can CRISPR Replace Antibiotics?
    Antibiotic-resistant infections claim around 700,000 lives per year, with estimates saying that this number could swell ...
    Written By: Annie Lennon
    1 1
    OCT 30, 2019
    Genetics & Genomics
    Disruptions in Mitochondrial Quality Control Can Cause Heart Disease
    Disruptions in Mitochondrial Quality Control Can Cause Heart Disease
    Researchers have learned why mutations in the ANT gene lead to heart problems.
    Written By: Carmen Leitch
    2
    OCT 22, 2019
    Cell & Molecular Biology
    Scientists Create a New Version of CRISPR - Prime Editing
    Scientists Create a New Version of CRISPR - Prime Editing
    A new technique enables researchers to target and modify one base pair out of billions, and could correct disease-causin ...
    Written By: Carmen Leitch
    2
    OCT 10, 2019
    Genetics & Genomics
    Gene-Editing Breakthrough for Cervical Cancer
    Gene-Editing Breakthrough for Cervical Cancer
    Researchers at the The Menzies Health Institute Queensland have found a way to use gene therapy CRISPR-Cas9 to treat cer ...
    Written By: Annie Lennon
    2
    OCT 06, 2019
    Microbiology
    Using CRISPR to Alter or Kill Bacteria
    Using CRISPR to Alter or Kill Bacteria
    In recent years, the gene editing tool CRISPR/Cas9 has been applied to a wide variety of different organisms, and now, b ...
    Written By: Carmen Leitch
    1
     
     
  • OCT 03, 2019
    Genetics & Genomics
    A More Precise Version of CRISPR/Cas9 is Created
    A More Precise Version of CRISPR/Cas9 is Created
    A more accurate version of Cas9 has been created, reducing the number of off-target effects. It may be better suited for ...
    Written By: Carmen Leitch
    1
    SEP 23, 2019
    Cell & Molecular Biology
    Using CRISPR to Track and Image Genome Editing in Real Time
    Using CRISPR to Track and Image Genome Editing in Real Time
    A team of scientists use fluorescently labeled proteins and CRISPR technology to image DNA transcription and chromosomal ...
    Written By: Carly Boyd
    1
    SEP 20, 2019
    Neuroscience
    Can CRISPR Technology Treat Alzheimer's?
    Can CRISPR Technology Treat Alzheimer's?
    New drugs that seek to treat Alzheimer’s disease (AD) have a 99.6% failure rate. This makes it the only disease in ...
    Written By: Annie Lennon
    1
    SEP 11, 2019
    Genetics & Genomics
    Rearranging Whole Chromosomes with CRISPR
    Rearranging Whole Chromosomes with CRISPR
    CRISPR/Cas9 was developed as a gene-editing tool and now it's going beyond small, targeted changes in the genome.
    Written By: Carmen Leitch
    2
    AUG 30, 2019
    Health & Medicine
    Mutant sheep bred to help scientists understand rare child brain disease
    Mutant sheep bred to help scientists understand rare child brain disease
    Scientists at Edinburgh University’s Roslin Institute have created a flock of sheep that carry the gene for a heri ...
    Written By: Dr. Nina Lichtenberg
    2
     
     
  • AUG 27, 2019
    Genetics & Genomics
    Using CRISPR to Edit the DNA Carried by Human Sperm
    Using CRISPR to Edit the DNA Carried by Human Sperm
    Efforts to edit the human genome are rolling forward, despite a call for a moratorium on heritable edits.
    Written By: Carmen Leitch
    1
    AUG 26, 2019
    Genetics & Genomics
    New Gene Editing Technology to Combat Hereditary Diseases
    New Gene Editing Technology to Combat Hereditary Diseases
    Until recently, many types of gene-editing methods were unable to target critical parts of DNA. Now however, researchers ...
    Written By: Annie Lennon
    2
    AUG 23, 2019
    Genetics & Genomics
    Altering Dozens or Hundreds of Genes at Once
    Altering Dozens or Hundreds of Genes at Once
    Since it was developed, the CRISPR gene editing system has been refined and advanced.
    Written By: Carmen Leitch
    3
    AUG 18, 2019
    Genetics & Genomics
    Modified CRISPR Can Manipulate Gene Activity in Neurons
    Modified CRISPR Can Manipulate Gene Activity in Neurons
    There are challenges to working with nerve cells in the lab, which can create research bottlenecks in the study of neuro ...
    Written By: Carmen Leitch
    1
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