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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • MAY 04, 2022 | 10:30 AM
      Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
      Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
      The coronavirus SARS-CoV-2 has led to a worldwide pandemic. Beside respiratory symptoms, infected people may develop neurologic dysfunctions such as loss of smell and taste, also seizures, a...
      Speaker: Susanne Krasemann, MD, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      4
      MAY 04, 2022 | 5:30 AM
      Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
      Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
      Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
      Speaker: Tracy Fischer, PhD
      Presented at: Coronavirus Series
      2
      MAY 03, 2022 | 8:00 AM
      Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
      Unlocking the genomics of cancer using Sanger sequencing and fragment...
      Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      APR 27, 2022 | 9:00 AM
      Tale of amyloid filaments in neurodegenerative diseases
      Tale of amyloid filaments in neurodegenerative diseases
      Date: April 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Abnormal accumulation of misfolded tau protein in filaments characterizes more than 20 neurodegenerative diseases—c...
      Speaker: Sofia Lövestam , Yang Shi , Abhay Kotecha, PhD
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific - Electron Microscopy
      6
      APR 26, 2022 | 7:00 AM
      High-Content Phenotypic Screening - Answering Questions You Haven't Even Asked Yet
      High-Content Phenotypic Screening - Answering Questions You Haven't...
      Date: April 19, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) High-content (HC) phenotypic profiling approaches are a powerful tool to study the effect of biological, genetic, and ch...
      Speaker: Dr. Angeline Lim , Dr. Victor Wong
      Sponsored By: Molecular Devices
      5
      APR 19, 2022 | 5:30 AM
      C.E. CREDITS
      Using Gene Regulatory Networks to Understand Sex Differences
      Using Gene Regulatory Networks to Understand Sex Differences
      Sex differences play an important role in development and progression of many diseases, and understanding how a disease differs between the sexes is essential for the advancement of preventi...
      Speaker: Camila Lopes-Ramos, PhD
      Presented at: Genetics Week Virtual Event Series 2022
      2
      APR 19, 2022 | 5:30 AM
      C.E. CREDITS
      Modelling the Accumulation of Mutations During Cancer Progression without Explicit Time
      Modelling the Accumulation of Mutations During Cancer Progression...
      Understanding the order in which mutations accumulate during cancer progression could help us identify effective therapeutic targets. Yet, our insights are limited by the fact that we can on...
      Speaker: Rebekka Burkholz, PhD
      Presented at: Genetics Week Virtual Event Series 2022
      2
      APR 06, 2022 | 5:30 AM
      Model-Assisted Design, Transfer and Scale-Up of an Antibody-Producing Cell Culture Process
      Model-Assisted Design, Transfer and Scale-Up of an Antibody-Producing...
      Biopharmaceuticals produced with mammalian cells are the key drivers for the medication of former untreatable diseases. The development of their production processes is still challenging bec...
      Speaker: Prof. Dr.-Ing. Habil. Ralf Pörtner
      Presented at: Bioprocessing Virtual Event Series 2022
      1
      APR 06, 2022 | 5:30 AM
      Optimising Cell Line Development for Bioprocessing
      Optimising Cell Line Development for Bioprocessing
      In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
      Speaker: Sami Ullah, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      5
      MAR 10, 2022 | 11:55 PM
      Higher Resolution Electrodes Improve Our Understanding Human Brain, Cognition, and Neurological Pathologies
      Higher Resolution Electrodes Improve Our Understanding Human Brain,...
      Neuroscience is experiencing an exciting era of integrating novel materials and tools to record neural activity made possible through significant advances in materials science, electrical en...
      Speaker: Angelique C. Paulk, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      1
      MAR 10, 2022 | 11:55 PM
      Characterizing Pathology-Inducing Protein Aggregates as Tools for Alzheimer's and Parkinson's Disease Models and Drug Discovery
      Characterizing Pathology-Inducing Protein Aggregates as Tools...
      Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in our society, no...
      Speaker: Jacob McPhail, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      2 1
      MAR 10, 2022 | 1:30 PM
      Utilization of the Luminex Platform to Discover and Develop Dual Toll-like Receptor 2 and 9 Antagonists for the Treatment of Neurodegenerative Diseases
      Utilization of the Luminex Platform to Discover and Develop Dual...
      Neuropore Therapies is discovering and developing novel small molecule disease-modifying therapeutics to treat patients with neurodegenerative diseases, including Parkinson’s disease a...
      Speaker: Diana L. Price, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      Sponsored By: Luminex - A DiaSorin Company
      1
      MAR 10, 2022 | 10:30 AM
      Automated 3D Light Sheet Microscopy: Opening New Dimensions in Neuroscience
      Automated 3D Light Sheet Microscopy: Opening New Dimensions in...
      The ability of light sheet microscopy to interrogate organoids, whole brain, and systems in 3D enables the study of complex neurological pathways, vasculature and disease models in unique wa...
      Speaker: Amanda Burke, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      Sponsored By: Miltenyi Biotec
      3
      FEB 24, 2022 | 9:00 AM
      Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate Detection and Interpretation of Cytokine Expression
      Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate...
      Date: February 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Cytokine profiling is a valuable tool used in preclinical research for monitoring an immune response and cell signaling pathways dur...
      Speaker: Laura Hocum Stone , Scott Hunter Oppler
      Sponsored By: ACD - A Bio-Techne Brand
      7
      FEB 23, 2022 | 11:55 PM
      Development and Characterization of an In Vitro Integrated Organ Platform for the Evaluation of Pharmacokinetic and Toxicologic Effects of Drugs and Chemicals
      Development and Characterization of an In Vitro Integrated Organ...
      The quest for alternatives to animal safety testing has fueled the development, characterization, and validation of many new technologies. There have been advances in cell and tissue models...
      Speaker: James McKim, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      3
      FEB 23, 2022 | 6:00 AM
      Autoantibodies as Biomarkers in Immuno-oncology
      Autoantibodies as Biomarkers in Immuno-oncology
      Cancer still accounts for nearly 1 in every 4 deaths worldwide. New immunotherapies have the power to induce durable responses in patients with fatal cancers, but only a small percentage of...
      Speaker: Hans-Dieter Zucht, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      Sponsored By: Luminex - A DiaSorin Company
      10
      DEC 08, 2021 | 11:00 AM
      Human Breast Organoid Models for Cancer Research
      Human Breast Organoid Models for Cancer Research
      Date: December 8, 2021 Time: 11:00am (PST), 2:00pam (EST) Breast cancer is the most common type of cancer and the leading cause of cancer deaths for women. Despite considerable ongoing resea...
      Speaker: Xiaojiang Cui, PhD
      Sponsored By: Akoya Biosciences
      12
      DEC 07, 2021 | 10:00 AM
      An overview of a novel RNAscopeâ„¢ in situ hybridization technology, and applications in pathology of animal models
      An overview of a novel RNAscopeâ„¢ in situ hybridization technology,...
      Date: December 07, 2021 Time: 10:00am (PST) The RNAscope™ technology allows high sensitivity and spatial resolution providing pivotal single-cell information to gain better insights in...
      Speaker: Anushka Dikshit, PhD , Sebastien Monette
      Sponsored By: ACD, a Bio-Techne brand
      1
      DEC 07, 2021 | 9:00 AM
      Enhanced ACE2 humanized rodent models to make COVID-19 research more translatable
      Enhanced ACE2 humanized rodent models to make COVID-19 research...
      Date: December 7, 2021 Time: 9:00am (PST), 12:00pm (EST) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than...
      Speaker: Justin Zhao, PhD
      Sponsored By: Envigo
      4 1
      OCT 26, 2021 | 11:00 AM
      Constructing a Spatially Resolved Single-cell Atlas of the Mouse Retina with the MERSCOPE Platform
      Constructing a Spatially Resolved Single-cell Atlas of the Mouse...
      Date: October 26, 2021 Time: 11:00am (PDT), 1:00pm (EDT) The retina is the light-sensing part of the visual system and is composed of six neuron types and several non-neuronal cell types, wi...
      Speaker: Rui Chen, B.S., Ph.D.
      Sponsored By: Vizgen
      5
      OCT 13, 2021 | 10:30 AM
      Altered MicroRNA Expression in COVID-19 Patients Accurately Identifies of SARS-CoV-2 Infection
      Altered MicroRNA Expression in COVID-19 Patients Accurately Identifies...
      By examining the host response to SARS-CoV-2 infection we gain valuable insights into viral pathogenesis and COVID-19 progression. MicroRNAs (miRNAs), a class of small (18-22nt), non-coding...
      Speaker: Ryan Farr, PhD
      Presented at: Coronavirus Series
      Sponsored By: QIAGEN
      1
      OCT 13, 2021 | 9:00 AM
      Keynote Presentation: Costly Closures: The Return on Investment in COVID-19 Prevention for Retail, School, Sports, and Entertainment
      Keynote Presentation: Costly Closures: The Return on Investment...
      Join me, an applied epidemiologist with boots on the ground, as we review key discoveries learned from the reopening of sports, entertainment and the arts. The four pillars of reopening incl...
      Speaker: Blythe Adamson, PhD, MPH
      Presented at: Coronavirus Series
      27
      SEP 29, 2021 | 11:00 AM
      Automating culture and high-content imaging of 3D organoids for in vitro assessment of compound effects
      Automating culture and high-content imaging of 3D organoids for...
      Date: Septembr 29, 2021 Time: 11:00am (PDT), 2:00pm (EDT) 3D cell models are becoming increasingly popular for studying complex biological effects, tissue functionality, and diseases. While...
      Speaker: Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      9
      SEP 17, 2021 | 12:00 PM
      Developing better techniques for 3D culture and analysis.
      Developing better techniques for 3D culture and analysis.
      Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
      Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
    MAY 04, 2022 | 10:30 AM
    Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
    Neuropathology of SARS-CoV-2 as Revealed by Spatial Biology
    The coronavirus SARS-CoV-2 has led to a worldwide pandemic. Beside respiratory symptoms, infected people may develop neurologic dysfunctions such as loss of smell and taste, also seizures, a...
    Speaker: Susanne Krasemann, MD, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    4
    MAY 04, 2022 | 5:30 AM
    Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
    Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
    Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
    Speaker: Tracy Fischer, PhD
    Presented at: Coronavirus Series
    2
    MAY 03, 2022 | 8:00 AM
    Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
    Unlocking the genomics of cancer using Sanger sequencing and fragment...
    Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    15
    APR 27, 2022 | 9:00 AM
    Tale of amyloid filaments in neurodegenerative diseases
    Tale of amyloid filaments in neurodegenerative diseases
    Date: April 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Abnormal accumulation of misfolded tau protein in filaments characterizes more than 20 neurodegenerative diseases—c...
    Speaker: Sofia Lövestam , Yang Shi , Abhay Kotecha, PhD
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific - Electron Microscopy
    6
    APR 26, 2022 | 7:00 AM
    High-Content Phenotypic Screening - Answering Questions You Haven't Even Asked Yet
    High-Content Phenotypic Screening - Answering Questions You Haven't...
    Date: April 19, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) High-content (HC) phenotypic profiling approaches are a powerful tool to study the effect of biological, genetic, and ch...
    Speaker: Dr. Angeline Lim , Dr. Victor Wong
    Sponsored By: Molecular Devices
    5
     
     
  • APR 19, 2022 | 5:30 AM
    C.E. CREDITS
    Using Gene Regulatory Networks to Understand Sex Differences
    Using Gene Regulatory Networks to Understand Sex Differences
    Sex differences play an important role in development and progression of many diseases, and understanding how a disease differs between the sexes is essential for the advancement of preventi...
    Speaker: Camila Lopes-Ramos, PhD
    Presented at: Genetics Week Virtual Event Series 2022
    2
    APR 19, 2022 | 5:30 AM
    C.E. CREDITS
    Modelling the Accumulation of Mutations During Cancer Progression without Explicit Time
    Modelling the Accumulation of Mutations During Cancer Progression...
    Understanding the order in which mutations accumulate during cancer progression could help us identify effective therapeutic targets. Yet, our insights are limited by the fact that we can on...
    Speaker: Rebekka Burkholz, PhD
    Presented at: Genetics Week Virtual Event Series 2022
    2
    APR 06, 2022 | 5:30 AM
    Model-Assisted Design, Transfer and Scale-Up of an Antibody-Producing Cell Culture Process
    Model-Assisted Design, Transfer and Scale-Up of an Antibody-Producing...
    Biopharmaceuticals produced with mammalian cells are the key drivers for the medication of former untreatable diseases. The development of their production processes is still challenging bec...
    Speaker: Prof. Dr.-Ing. Habil. Ralf Pörtner
    Presented at: Bioprocessing Virtual Event Series 2022
    1
    APR 06, 2022 | 5:30 AM
    Optimising Cell Line Development for Bioprocessing
    Optimising Cell Line Development for Bioprocessing
    In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
    Speaker: Sami Ullah, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    5
    MAR 10, 2022 | 11:55 PM
    Higher Resolution Electrodes Improve Our Understanding Human Brain, Cognition, and Neurological Pathologies
    Higher Resolution Electrodes Improve Our Understanding Human Brain,...
    Neuroscience is experiencing an exciting era of integrating novel materials and tools to record neural activity made possible through significant advances in materials science, electrical en...
    Speaker: Angelique C. Paulk, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    1
     
     
  • MAR 10, 2022 | 11:55 PM
    Characterizing Pathology-Inducing Protein Aggregates as Tools for Alzheimer's and Parkinson's Disease Models and Drug Discovery
    Characterizing Pathology-Inducing Protein Aggregates as Tools...
    Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Despite their debilitating effects and increasing prevalence in our society, no...
    Speaker: Jacob McPhail, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    2 1
    MAR 10, 2022 | 1:30 PM
    Utilization of the Luminex Platform to Discover and Develop Dual Toll-like Receptor 2 and 9 Antagonists for the Treatment of Neurodegenerative Diseases
    Utilization of the Luminex Platform to Discover and Develop Dual...
    Neuropore Therapies is discovering and developing novel small molecule disease-modifying therapeutics to treat patients with neurodegenerative diseases, including Parkinson’s disease a...
    Speaker: Diana L. Price, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    Sponsored By: Luminex - A DiaSorin Company
    1
    MAR 10, 2022 | 10:30 AM
    Automated 3D Light Sheet Microscopy: Opening New Dimensions in Neuroscience
    Automated 3D Light Sheet Microscopy: Opening New Dimensions in...
    The ability of light sheet microscopy to interrogate organoids, whole brain, and systems in 3D enables the study of complex neurological pathways, vasculature and disease models in unique wa...
    Speaker: Amanda Burke, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    Sponsored By: Miltenyi Biotec
    3
    FEB 24, 2022 | 9:00 AM
    Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate Detection and Interpretation of Cytokine Expression
    Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate...
    Date: February 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Cytokine profiling is a valuable tool used in preclinical research for monitoring an immune response and cell signaling pathways dur...
    Speaker: Laura Hocum Stone , Scott Hunter Oppler
    Sponsored By: ACD - A Bio-Techne Brand
    7
    FEB 23, 2022 | 11:55 PM
    Development and Characterization of an In Vitro Integrated Organ Platform for the Evaluation of Pharmacokinetic and Toxicologic Effects of Drugs and Chemicals
    Development and Characterization of an In Vitro Integrated Organ...
    The quest for alternatives to animal safety testing has fueled the development, characterization, and validation of many new technologies. There have been advances in cell and tissue models...
    Speaker: James McKim, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    3
     
     
  • FEB 23, 2022 | 6:00 AM
    Autoantibodies as Biomarkers in Immuno-oncology
    Autoantibodies as Biomarkers in Immuno-oncology
    Cancer still accounts for nearly 1 in every 4 deaths worldwide. New immunotherapies have the power to induce durable responses in patients with fatal cancers, but only a small percentage of...
    Speaker: Hans-Dieter Zucht, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    Sponsored By: Luminex - A DiaSorin Company
    10
    DEC 08, 2021 | 11:00 AM
    Human Breast Organoid Models for Cancer Research
    Human Breast Organoid Models for Cancer Research
    Date: December 8, 2021 Time: 11:00am (PST), 2:00pam (EST) Breast cancer is the most common type of cancer and the leading cause of cancer deaths for women. Despite considerable ongoing resea...
    Speaker: Xiaojiang Cui, PhD
    Sponsored By: Akoya Biosciences
    12
    DEC 07, 2021 | 10:00 AM
    An overview of a novel RNAscopeâ„¢ in situ hybridization technology, and applications in pathology of animal models
    An overview of a novel RNAscopeâ„¢ in situ hybridization technology,...
    Date: December 07, 2021 Time: 10:00am (PST) The RNAscope™ technology allows high sensitivity and spatial resolution providing pivotal single-cell information to gain better insights in...
    Speaker: Anushka Dikshit, PhD , Sebastien Monette
    Sponsored By: ACD, a Bio-Techne brand
    1
    DEC 07, 2021 | 9:00 AM
    Enhanced ACE2 humanized rodent models to make COVID-19 research more translatable
    Enhanced ACE2 humanized rodent models to make COVID-19 research...
    Date: December 7, 2021 Time: 9:00am (PST), 12:00pm (EST) The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than...
    Speaker: Justin Zhao, PhD
    Sponsored By: Envigo
    4 1
    OCT 26, 2021 | 11:00 AM
    Constructing a Spatially Resolved Single-cell Atlas of the Mouse Retina with the MERSCOPE Platform
    Constructing a Spatially Resolved Single-cell Atlas of the Mouse...
    Date: October 26, 2021 Time: 11:00am (PDT), 1:00pm (EDT) The retina is the light-sensing part of the visual system and is composed of six neuron types and several non-neuronal cell types, wi...
    Speaker: Rui Chen, B.S., Ph.D.
    Sponsored By: Vizgen
    5
     
     
  • OCT 13, 2021 | 10:30 AM
    Altered MicroRNA Expression in COVID-19 Patients Accurately Identifies of SARS-CoV-2 Infection
    Altered MicroRNA Expression in COVID-19 Patients Accurately Identifies...
    By examining the host response to SARS-CoV-2 infection we gain valuable insights into viral pathogenesis and COVID-19 progression. MicroRNAs (miRNAs), a class of small (18-22nt), non-coding...
    Speaker: Ryan Farr, PhD
    Presented at: Coronavirus Series
    Sponsored By: QIAGEN
    1
    OCT 13, 2021 | 9:00 AM
    Keynote Presentation: Costly Closures: The Return on Investment in COVID-19 Prevention for Retail, School, Sports, and Entertainment
    Keynote Presentation: Costly Closures: The Return on Investment...
    Join me, an applied epidemiologist with boots on the ground, as we review key discoveries learned from the reopening of sports, entertainment and the arts. The four pillars of reopening incl...
    Speaker: Blythe Adamson, PhD, MPH
    Presented at: Coronavirus Series
    27
    SEP 29, 2021 | 11:00 AM
    Automating culture and high-content imaging of 3D organoids for in vitro assessment of compound effects
    Automating culture and high-content imaging of 3D organoids for...
    Date: Septembr 29, 2021 Time: 11:00am (PDT), 2:00pm (EDT) 3D cell models are becoming increasingly popular for studying complex biological effects, tissue functionality, and diseases. While...
    Speaker: Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    9
    SEP 17, 2021 | 12:00 PM
    Developing better techniques for 3D culture and analysis.
    Developing better techniques for 3D culture and analysis.
    Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
    Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
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