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    Disease Modeling

    Disease modeling is the use of a disease model, which is an animal or cells containing all or some of the pathological characteristics and mechanisms of a disease, to study that particular disease.

    Webinars

    • JUL 09, 2020 | 11:00 AM
      Learning to aggress: from complex social behavior to whole brain light sheet microscopy
      Learning to aggress: from complex social behavior to whole brain...
      DATE: July 9, 2020 TIME: 11:00am PT Maladaptive aggression is an immutable force that contributes to the suffering and death of millions of people around the world annually, as well as prese...
      Speaker: Sam Golden, Ph.D
      Sponsored By: Miltenyi Biotec
      10
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 18, 2020 | 9:00 AM
      Unveiling the role of T cell dysfunction in the development and progression of glioblastoma
      Unveiling the role of T cell dysfunction in the development and...
      DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
      Speaker: Felipe Galvez Cancino, Ph.D.
      Sponsored By: Thermo Fisher Scientific/Gibco
      18 2
      JUN 17, 2020 | 6:00 AM
      Rapid Development of Multiplex Serological Assays for COVID-19 Beyond
      Rapid Development of Multiplex Serological Assays for COVID-19...
      Since the outbreak of the Covid-19 pandemic, the development of diagnostics for both the virus (molecular) and the host immune response (serological) has become essential for monitoring the...
      Speaker: Steve Angeloni , Nicole Pecora, MD, PhD
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUN 09, 2020 | 6:00 AM
      Smart Plastics: Improving qPCR reliability & reproducibility
      Smart Plastics: Improving qPCR reliability & reproducibility
      DATE: June 9, 2020 TIME: 6am PT, 9am ET, 3pm CEST The importance of disposable plastic consumables and their overall impact on the experimental workflow of qPCR has been taken into considera...
      Speaker: Michael Pfaffl, Ph.D. , Tim Schommartz, PhD , Rafal Grzeskowiak, PhD
      Sponsored By: Eppendorf
      39
      JUN 03, 2020 | 8:00 AM
      Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment) in Experimental and Diagnostic Pathology
      Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment)...
      Cancer initiation and virulence depends on mechanisms to evade host immunosurveillance and suppression of early invasion and growth. Distinct phenotypes of the immune infiltrates in and arou...
      Speaker: Alexander David Borowsky, MD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Leica Biosystems
      1
      MAY 28, 2020 | 9:00 AM
      Detection of Chemical Agents in Bone by LC-MS
      Detection of Chemical Agents in Bone by LC-MS
      A recently proposed model for the incorporation of xenobiotics of clinical and forensic interest into the human skeleton suggests nerve agent metabolites may incorporate into bone at relativ...
      Speaker: Timothy Garrett, PhD
      Presented at: Healthcare Heroes - Clinical Customer Appreciation Symposium
      1
      MAY 20, 2020 | 1:15 PM
      Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells & CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment...
      Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart®...
      Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
      Speaker: Jan Davidson, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 11:15 AM
      Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant Ribociclib Plus Letrozole Versus Chemotherapy in PAM50 Luminal B Early Breast Cancer
      Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant...
      Background: CDK4/6 inhibitors increase tumor immunogenicity in preclinical models of breast cancer and several trials combining CDK4/6 inhibitors and anti-PD1/PDL1 therapies are underway. Ho...
      Speaker: Aleix Prat, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 20, 2020 | 12:00 AM
      Single-cell Genomics Tools for better understanding and treatment of Human Disease
      Single-cell Genomics Tools for better understanding and treatment...
      The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
      Speaker: Anindita Basu, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      2
      MAY 19, 2020 | 1:15 PM
      Immune Infiltration Influences the Survival of Pancreatic Cancer Patients
      Immune Infiltration Influences the Survival of Pancreatic Cancer...
      Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
      Speaker: Dana Mustafa, Ph.D.
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 14, 2020 | 12:00 AM
      Tissue Chips: Building Confidence Through Independent Experimental Testing
      Tissue Chips: Building Confidence Through Independent Experimental...
      Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by b...
      Speaker: Ivan Rusyn, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      0
      MAY 14, 2020 | 12:00 AM
      Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel Cage-Side Measures
      Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel...
      The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test...
      Speaker: Jennifer Lofgren, DVM, MS, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      0
      MAY 13, 2020 | 7:00 AM
      Stem cell culture: Make or break - Find the optimum for your MSCs and PSCs
      Stem cell culture: Make or break - Find the optimum for your MSCs...
      DATE: May 13, 2020 TIME: 7am PT, 10am ET, 4pm CEST Stem cells represent an important tool in a wide range of applications, including basic research, disease modeling, drug discovery, and reg...
      Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
      Sponsored By: Eppendorf
      37
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      MAY 12, 2020 | 8:00 AM
      Deep phenotyping of Tregs in health and disease - lessons from Bone Marrow Failure Syndromes
      Deep phenotyping of Tregs in health and disease - lessons from...
      DATE: May 12, 2020 TIME: 8:00am PT Idiopathic aplastic anemia (AA) has two key characteristics: an autoimmune response against hematopoietic stem/progenitor cells and regulatory T cells (Tre...
      Speaker: Dr. Shahram Kordasti
      Sponsored By: Beckman Coulter Life Sciences
      13 3
      MAY 08, 2020 | 10:00 AM
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
      DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
      Speaker: Brian O'Connor, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      16 10
      APR 30, 2020 | 7:00 AM
      Nucleic Acid Purification - Understand the details, tackle the routines!
      Nucleic Acid Purification - Understand the details, tackle the...
      DATE: April 30, 2020 TIME: 7am PT, 10am ET, 4pm CEST Aged more than one century, nucleic acid purification is anything but ordinary. Nucleic Acid Purification, also termed Nucleic Acid Extra...
      Speaker: Andreas von Bohl, PhD , Milan Dieris, PhD , Tim Schommartz, PhD
      Sponsored By: Eppendorf, Macherey-Nagel
      45 13
      APR 29, 2020 | 6:00 AM
      Antitumor Immune Activity $ Safety of a Novel PD-1 Vaccine Alone & in Combination With 2 Chimeric HER-2 Peptide Vaccine in Syngeneic Balb/C & C57Bl/6 Models & in Canine and Non-Human Primates
      Antitumor Immune Activity $ Safety of a Novel PD-1 Vaccine Alone...
      ...
      Speaker: Pravin Kaumaya, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 29, 2020 | 6:00 AM
      Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically Meaningful Subsets: Immune Signatures as a Lens for Discovery
      Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically...
      ...
      Speaker: Mady Hornig, MA, MD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      2
      APR 24, 2020 | 8:00 AM
      The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
      The International Council for Standardisation in Hematology (ICSH)...
      The International Council for Standardization in Haematology (ICSH) is a nonprofit organization dedicated to providing open-access guidance documents to enhance the quality of laboratory tes...
      Speaker: Bob Gosselin
      Sponsored By: Diagnostica Stago, Inc.
      10
      APR 22, 2020 | 8:00 AM
      C.E. CREDITS
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      Discover strategies for labs to optimize coagulation testing, improve patient outcomes, and strengthen their role in clinical care teams....
      Speaker: Eleanor Herriman, MD, MBA , Oksana Volod, MD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      7
      APR 21, 2020 | 7:30 AM
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
      Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
      Speaker: Scott Soderling, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: CasTag Biosciences
      1 1
      APR 20, 2020 | 8:00 AM
      C.E. CREDITS
      Emergency patient management using coagulation assays
      Emergency patient management using coagulation assays
      Explore emergency hemostasis testing approaches, from rapid lab assays to viscoelastic methods, for managing bleeding patients....
      Speaker: Wayne Chandler, MD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      17 5
    JUL 09, 2020 | 11:00 AM
    Learning to aggress: from complex social behavior to whole brain light sheet microscopy
    Learning to aggress: from complex social behavior to whole brain...
    DATE: July 9, 2020 TIME: 11:00am PT Maladaptive aggression is an immutable force that contributes to the suffering and death of millions of people around the world annually, as well as prese...
    Speaker: Sam Golden, Ph.D
    Sponsored By: Miltenyi Biotec
    10
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    JUN 18, 2020 | 9:00 AM
    Unveiling the role of T cell dysfunction in the development and progression of glioblastoma
    Unveiling the role of T cell dysfunction in the development and...
    DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
    Speaker: Felipe Galvez Cancino, Ph.D.
    Sponsored By: Thermo Fisher Scientific/Gibco
    18 2
    JUN 17, 2020 | 6:00 AM
    Rapid Development of Multiplex Serological Assays for COVID-19 Beyond
    Rapid Development of Multiplex Serological Assays for COVID-19...
    Since the outbreak of the Covid-19 pandemic, the development of diagnostics for both the virus (molecular) and the host immune response (serological) has become essential for monitoring the...
    Speaker: Steve Angeloni , Nicole Pecora, MD, PhD
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    1
    JUN 09, 2020 | 6:00 AM
    Smart Plastics: Improving qPCR reliability & reproducibility
    Smart Plastics: Improving qPCR reliability & reproducibility
    DATE: June 9, 2020 TIME: 6am PT, 9am ET, 3pm CEST The importance of disposable plastic consumables and their overall impact on the experimental workflow of qPCR has been taken into considera...
    Speaker: Michael Pfaffl, Ph.D. , Tim Schommartz, PhD , Rafal Grzeskowiak, PhD
    Sponsored By: Eppendorf
    39
     
     
  • JUN 03, 2020 | 8:00 AM
    Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment) in Experimental and Diagnostic Pathology
    Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment)...
    Cancer initiation and virulence depends on mechanisms to evade host immunosurveillance and suppression of early invasion and growth. Distinct phenotypes of the immune infiltrates in and arou...
    Speaker: Alexander David Borowsky, MD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Leica Biosystems
    1
    MAY 28, 2020 | 9:00 AM
    Detection of Chemical Agents in Bone by LC-MS
    Detection of Chemical Agents in Bone by LC-MS
    A recently proposed model for the incorporation of xenobiotics of clinical and forensic interest into the human skeleton suggests nerve agent metabolites may incorporate into bone at relativ...
    Speaker: Timothy Garrett, PhD
    Presented at: Healthcare Heroes - Clinical Customer Appreciation Symposium
    1
    MAY 20, 2020 | 1:15 PM
    Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells & CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment...
    Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart®...
    Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
    Speaker: Jan Davidson, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 20, 2020 | 11:15 AM
    Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant Ribociclib Plus Letrozole Versus Chemotherapy in PAM50 Luminal B Early Breast Cancer
    Primary Results of SOLTI-1402/CORALLEEN Phase 2 Trial of Neoadjuvant...
    Background: CDK4/6 inhibitors increase tumor immunogenicity in preclinical models of breast cancer and several trials combining CDK4/6 inhibitors and anti-PD1/PDL1 therapies are underway. Ho...
    Speaker: Aleix Prat, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 20, 2020 | 12:00 AM
    Single-cell Genomics Tools for better understanding and treatment of Human Disease
    Single-cell Genomics Tools for better understanding and treatment...
    The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
    Speaker: Anindita Basu, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    2
     
     
  • MAY 19, 2020 | 1:15 PM
    Immune Infiltration Influences the Survival of Pancreatic Cancer Patients
    Immune Infiltration Influences the Survival of Pancreatic Cancer...
    Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
    Speaker: Dana Mustafa, Ph.D.
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 14, 2020 | 12:00 AM
    Tissue Chips: Building Confidence Through Independent Experimental Testing
    Tissue Chips: Building Confidence Through Independent Experimental...
    Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by b...
    Speaker: Ivan Rusyn, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    0
    MAY 14, 2020 | 12:00 AM
    Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel Cage-Side Measures
    Evaluation of Analgesia Efficacy in Postoperative Mice Using Novel...
    The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test...
    Speaker: Jennifer Lofgren, DVM, MS, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    0
    MAY 13, 2020 | 7:00 AM
    Stem cell culture: Make or break - Find the optimum for your MSCs and PSCs
    Stem cell culture: Make or break - Find the optimum for your MSCs...
    DATE: May 13, 2020 TIME: 7am PT, 10am ET, 4pm CEST Stem cells represent an important tool in a wide range of applications, including basic research, disease modeling, drug discovery, and reg...
    Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
    Sponsored By: Eppendorf
    37
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
     
     
  • MAY 12, 2020 | 8:00 AM
    Deep phenotyping of Tregs in health and disease - lessons from Bone Marrow Failure Syndromes
    Deep phenotyping of Tregs in health and disease - lessons from...
    DATE: May 12, 2020 TIME: 8:00am PT Idiopathic aplastic anemia (AA) has two key characteristics: an autoimmune response against hematopoietic stem/progenitor cells and regulatory T cells (Tre...
    Speaker: Dr. Shahram Kordasti
    Sponsored By: Beckman Coulter Life Sciences
    13 3
    MAY 08, 2020 | 10:00 AM
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    Speaker: Brian O'Connor, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    16 10
    APR 30, 2020 | 7:00 AM
    Nucleic Acid Purification - Understand the details, tackle the routines!
    Nucleic Acid Purification - Understand the details, tackle the...
    DATE: April 30, 2020 TIME: 7am PT, 10am ET, 4pm CEST Aged more than one century, nucleic acid purification is anything but ordinary. Nucleic Acid Purification, also termed Nucleic Acid Extra...
    Speaker: Andreas von Bohl, PhD , Milan Dieris, PhD , Tim Schommartz, PhD
    Sponsored By: Eppendorf, Macherey-Nagel
    45 13
    APR 29, 2020 | 6:00 AM
    Antitumor Immune Activity $ Safety of a Novel PD-1 Vaccine Alone & in Combination With 2 Chimeric HER-2 Peptide Vaccine in Syngeneic Balb/C & C57Bl/6 Models & in Canine and Non-Human Primates
    Antitumor Immune Activity $ Safety of a Novel PD-1 Vaccine Alone...
    ...
    Speaker: Pravin Kaumaya, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 29, 2020 | 6:00 AM
    Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically Meaningful Subsets: Immune Signatures as a Lens for Discovery
    Parsing Complex Disorders of the Gut-Immune-Brain Axis Into Clinically...
    ...
    Speaker: Mady Hornig, MA, MD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    2
     
     
  • APR 24, 2020 | 8:00 AM
    The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
    The International Council for Standardisation in Hematology (ICSH)...
    The International Council for Standardization in Haematology (ICSH) is a nonprofit organization dedicated to providing open-access guidance documents to enhance the quality of laboratory tes...
    Speaker: Bob Gosselin
    Sponsored By: Diagnostica Stago, Inc.
    10
    APR 22, 2020 | 8:00 AM
    C.E. CREDITS
    The NEW Coag Value Playbook...Embrace the Power of Local Testing
    The NEW Coag Value Playbook...Embrace the Power of Local Testing
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