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    DNA-Binding Proteins

    DNA Binding Proteins: DNA-binding proteins are proteins composed of DNA-binding domains and thus have a specific or general affinity for either single or double stranded DNA. Sequence-specific DNA-binding proteins generally interact with the major groove of B-DNA, because it exposes more functional groups that identify a base pair..

    Webinars

    • FEB 15, 2023 | 7:00 AM
      Scattering Microscopy: Label-Free Imaging Approaches
      Scattering Microscopy: Label-Free Imaging Approaches
      Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
      Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
      Sponsored By: Teledyne Photometrics
      28
      JAN 25, 2023 | 10:00 AM
      Single-Molecule Proteomics using Protein Identification by Short-epitope Mapping
      Single-Molecule Proteomics using Protein Identification by Short-epitope...
      Date: January 25, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) The field of proteomics is poised for a single-molecule revolution – enabling more comprehensive analysis of the...
      Speaker: Parag Mallick, Ph.D.
      Sponsored By: Nautilus Biotechnology
      19
      SEP 29, 2022 | 7:00 AM
      Multidimensional Approach to Decoding the Mysteries of Animal Development
      Multidimensional Approach to Decoding the Mysteries of Animal...
      Date: September 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Development and evolution are controlled, to a large degree, by regions of genomic DNA called enhancers that encode...
      Speaker: Justin Crocker
      Sponsored By: GenScript
      7
      SEP 20, 2022 | 7:00 AM
      Tips and Tricks -  When Using Filter Plates or Spin Devices with Nucleic Acid, Protein Purification and Cloning Applications
      Tips and Tricks - When Using Filter Plates or Spin Devices with...
      Date: September 20, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Filtration is a critical component of sample preparation and choosing the correct filtration device affects the resu...
      Speaker: Laima Fabule, Ph.D.
      Sponsored By: Pall Life Sciences
      8
      MAY 19, 2022 | 8:00 AM
      Automated sample preparation for reproducible clinical proteomics
      Automated sample preparation for reproducible clinical proteomics
      Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
      Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
      Sponsored By: Covaris, Inc.
      14
      NOV 08, 2021 | 8:00 AM
      Learn how to maximize KingFisher instruments to automate DNA, RNA, proteins & cells for all applications
      Learn how to maximize KingFisher instruments to automate DNA,...
      Date: November 8, 2021 Time: 8:00am (PDT), 11:00am (EDT) Explore the adaptability of your KingFisher instrument. Discover all the ways your Thermo Scientific™ KingFisher™ system...
      Speaker: Ketil Pedersen, Ph.D , Emily Zeringer , Suraj Patel, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      9
      OCT 14, 2021 | 9:00 AM
      Session 3: Simple steps to publication-quality western blots
      Session 3: Simple steps to publication-quality western blots
      Date: October 14, 2021 Time: 9:00am (PDT), 12:00pm (EDT), 5:00pm GMT Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring spe...
      Speaker: Kelli Feather-Henigan
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      28
      OCT 14, 2021 | 7:00 AM
      Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
      Heterologous Protein Engineering and characterization of native...
      Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      22
      OCT 13, 2021 | 7:00 AM
      Session 2: Simple steps to publication-quality western blots
      Session 2: Simple steps to publication-quality western blots
      Date: October 13, 2021 Time: 7:00am (PDT), 10:00am (EDT) Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring specific target...
      Speaker: Caleb Shearrow
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      31 1
      OCT 12, 2021 | 5:00 PM
      Session 1: Simple steps to publication-quality western blots
      Session 1: Simple steps to publication-quality western blots
      Date: October 12, 2021 Time: 5:00pm (PDT), 8:00pm (EDT) 222 Learning Objectives 222 222 222 Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved...
      Speaker: Jordan Thompson, PhD
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      39 1
      SEP 14, 2021 | 7:00 AM
      What prevents you from increasing your PCR productivity?
      What prevents you from increasing your PCR productivity?
      Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
      Speaker: Arora Phang, PhD
      Sponsored By: Eppendorf
      24 1
      JUN 09, 2021 | 7:00 AM
      Preventing cell misidentification in your daily lab routine
      Preventing cell misidentification in your daily lab routine
      Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
      Speaker: Gabriela Saldanha , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      40 3
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
      APR 20, 2021 | 12:00 AM
      Measurement of DNA Methylation and Nuclear Organization with Nanopore Sequencing
      Measurement of DNA Methylation and Nuclear Organization with Nanopore...
      Nanopore sequencing has enormous potential in epigenetic applications; unlike traditional sequencing-by-synthesis technologies, it can distinguish covalently modified nucleotides directly th...
      Speaker: Roham Razaghi, PhD Candidate
      Presented at: Genetics Week Virtual Event Series 2021
      1
      MAR 31, 2021 | 9:00 AM
      Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored targeting
      Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored...
      Date: March 31, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Knockdown studies are prevalent and powerful ways to illustrate gene function. CRISPRi delivers a new mechanism for gene knockdown, PAM...
      Speaker: Steve Smith, PhD, MBA
      Sponsored By: Horizon Discovery
      12 2
      FEB 24, 2021 | 7:00 AM
      DeepCLIP: Predicting the effect of mutations on protein-RNA binding with deep learning
      DeepCLIP: Predicting the effect of mutations on protein-RNA binding...
      Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
      Speaker: Thomas Doktor, PhD.
      Sponsored By: GenScript
      12
      DEC 15, 2020 | 10:00 AM
      Prep for Success: From human microbiome exploration to advanced SARS-CoV-2 testing in wastewater
      Prep for Success: From human microbiome exploration to advanced...
      DATE: December 15, 2020 TIME: 10:00am PST Scientists from Thermo Fisher Scientific will walk us through the world of microorganisms. They will discuss their most recent research on viruses,...
      Speaker: Sasha Vlassov, PhD , Jasti Madhu , Emily Zeringer
      Sponsored By: Thermo Fisher Scientific
      13
      DEC 02, 2020 | 8:00 AM
      Optimize your bioprocess - From shaker to bioreactor
      Optimize your bioprocess - From shaker to bioreactor
      DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
      Speaker: Ines Hartmann , David Solbach
      Sponsored By: Eppendorf
      11
      NOV 19, 2020 | 9:00 AM
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
      Speaker: Kok Hao Chen , Alan Mullan, PhD
      Sponsored By: Andor
      6 2
      NOV 05, 2020 | 7:00 AM
      Stem cell derived exosome production in stirred-tank bioreactors
      Stem cell derived exosome production in stirred-tank bioreactors
      DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
      Speaker: Jorge Escobar , Aurélie Tacheny
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      12
      OCT 08, 2020 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
      Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      33 5
      SEP 30, 2020 | 1:30 PM
      Harnessing novel CRISPR systems for genome engineering
      Harnessing novel CRISPR systems for genome engineering
      RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: CRISPR Virtual Event Series 2020
      4
      SEP 10, 2020 | 12:00 AM
      Visualizing viral replication of oncogenic human herpesviruses
      Visualizing viral replication of oncogenic human herpesviruses
      Viruses are the causative agents of approximately 12% of human cancers. The most recently discovered herpesvirus, Kaposi’s sarcoma herpesvirus (KSHV) is known to cause three human canc...
      Speaker: Lindsey M. Costantini, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 03, 2020 | 11:00 AM
      Filtered Fume Hoods: Expert insight on improving your lab's green initiative
      Filtered Fume Hoods: Expert insight on improving your lab's green...
      DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
      Speaker: Kasey Fulmer , Kenneth Crooks
      Sponsored By: Labconco
      11
    FEB 15, 2023 | 7:00 AM
    Scattering Microscopy: Label-Free Imaging Approaches
    Scattering Microscopy: Label-Free Imaging Approaches
    Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
    Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
    Sponsored By: Teledyne Photometrics
    28
    JAN 25, 2023 | 10:00 AM
    Single-Molecule Proteomics using Protein Identification by Short-epitope Mapping
    Single-Molecule Proteomics using Protein Identification by Short-epitope...
    Date: January 25, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) The field of proteomics is poised for a single-molecule revolution – enabling more comprehensive analysis of the...
    Speaker: Parag Mallick, Ph.D.
    Sponsored By: Nautilus Biotechnology
    19
    SEP 29, 2022 | 7:00 AM
    Multidimensional Approach to Decoding the Mysteries of Animal Development
    Multidimensional Approach to Decoding the Mysteries of Animal...
    Date: September 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Development and evolution are controlled, to a large degree, by regions of genomic DNA called enhancers that encode...
    Speaker: Justin Crocker
    Sponsored By: GenScript
    7
    SEP 20, 2022 | 7:00 AM
    Tips and Tricks -  When Using Filter Plates or Spin Devices with Nucleic Acid, Protein Purification and Cloning Applications
    Tips and Tricks - When Using Filter Plates or Spin Devices with...
    Date: September 20, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Filtration is a critical component of sample preparation and choosing the correct filtration device affects the resu...
    Speaker: Laima Fabule, Ph.D.
    Sponsored By: Pall Life Sciences
    8
    MAY 19, 2022 | 8:00 AM
    Automated sample preparation for reproducible clinical proteomics
    Automated sample preparation for reproducible clinical proteomics
    Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
    Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
    Sponsored By: Covaris, Inc.
    14
     
     
  • NOV 08, 2021 | 8:00 AM
    Learn how to maximize KingFisher instruments to automate DNA, RNA, proteins & cells for all applications
    Learn how to maximize KingFisher instruments to automate DNA,...
    Date: November 8, 2021 Time: 8:00am (PDT), 11:00am (EDT) Explore the adaptability of your KingFisher instrument. Discover all the ways your Thermo Scientific™ KingFisher™ system...
    Speaker: Ketil Pedersen, Ph.D , Emily Zeringer , Suraj Patel, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    9
    OCT 14, 2021 | 9:00 AM
    Session 3: Simple steps to publication-quality western blots
    Session 3: Simple steps to publication-quality western blots
    Date: October 14, 2021 Time: 9:00am (PDT), 12:00pm (EDT), 5:00pm GMT Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring spe...
    Speaker: Kelli Feather-Henigan
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    28
    OCT 14, 2021 | 7:00 AM
    Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
    Heterologous Protein Engineering and characterization of native...
    Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    22
    OCT 13, 2021 | 7:00 AM
    Session 2: Simple steps to publication-quality western blots
    Session 2: Simple steps to publication-quality western blots
    Date: October 13, 2021 Time: 7:00am (PDT), 10:00am (EDT) Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring specific target...
    Speaker: Caleb Shearrow
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    31 1
    OCT 12, 2021 | 5:00 PM
    Session 1: Simple steps to publication-quality western blots
    Session 1: Simple steps to publication-quality western blots
    Date: October 12, 2021 Time: 5:00pm (PDT), 8:00pm (EDT) 222 Learning Objectives 222 222 222 Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved...
    Speaker: Jordan Thompson, PhD
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    39 1
     
     
  • SEP 14, 2021 | 7:00 AM
    What prevents you from increasing your PCR productivity?
    What prevents you from increasing your PCR productivity?
    Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
    Speaker: Arora Phang, PhD
    Sponsored By: Eppendorf
    24 1
    JUN 09, 2021 | 7:00 AM
    Preventing cell misidentification in your daily lab routine
    Preventing cell misidentification in your daily lab routine
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    Speaker: Gabriela Saldanha , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    40 3
    MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    APR 20, 2021 | 12:00 AM
    Measurement of DNA Methylation and Nuclear Organization with Nanopore Sequencing
    Measurement of DNA Methylation and Nuclear Organization with Nanopore...
    Nanopore sequencing has enormous potential in epigenetic applications; unlike traditional sequencing-by-synthesis technologies, it can distinguish covalently modified nucleotides directly th...
    Speaker: Roham Razaghi, PhD Candidate
    Presented at: Genetics Week Virtual Event Series 2021
    1
    MAR 31, 2021 | 9:00 AM
    Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored targeting
    Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored...
    Date: March 31, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Knockdown studies are prevalent and powerful ways to illustrate gene function. CRISPRi delivers a new mechanism for gene knockdown, PAM...
    Speaker: Steve Smith, PhD, MBA
    Sponsored By: Horizon Discovery
    12 2
     
     
  • FEB 24, 2021 | 7:00 AM
    DeepCLIP: Predicting the effect of mutations on protein-RNA binding with deep learning
    DeepCLIP: Predicting the effect of mutations on protein-RNA binding...
    Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
    Speaker: Thomas Doktor, PhD.
    Sponsored By: GenScript
    12
    DEC 15, 2020 | 10:00 AM
    Prep for Success: From human microbiome exploration to advanced SARS-CoV-2 testing in wastewater
    Prep for Success: From human microbiome exploration to advanced...
    DATE: December 15, 2020 TIME: 10:00am PST Scientists from Thermo Fisher Scientific will walk us through the world of microorganisms. They will discuss their most recent research on viruses,...
    Speaker: Sasha Vlassov, PhD , Jasti Madhu , Emily Zeringer
    Sponsored By: Thermo Fisher Scientific
    13
    DEC 02, 2020 | 8:00 AM
    Optimize your bioprocess - From shaker to bioreactor
    Optimize your bioprocess - From shaker to bioreactor
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    Speaker: Ines Hartmann , David Solbach
    Sponsored By: Eppendorf
    11
    NOV 19, 2020 | 9:00 AM
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
    Speaker: Kok Hao Chen , Alan Mullan, PhD
    Sponsored By: Andor
    6 2
    NOV 05, 2020 | 7:00 AM
    Stem cell derived exosome production in stirred-tank bioreactors
    Stem cell derived exosome production in stirred-tank bioreactors
    DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
    Speaker: Jorge Escobar , Aurélie Tacheny
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    12
     
     
  • OCT 08, 2020 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    33 5
    SEP 30, 2020 | 1:30 PM
    Harnessing novel CRISPR systems for genome engineering
    Harnessing novel CRISPR systems for genome engineering
    RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: CRISPR Virtual Event Series 2020
    4
    SEP 10, 2020 | 12:00 AM
    Visualizing viral replication of oncogenic human herpesviruses
    Visualizing viral replication of oncogenic human herpesviruses
    Viruses are the causative agents of approximately 12% of human cancers. The most recently discovered herpesvirus, Kaposi’s sarcoma herpesvirus (KSHV) is known to cause three human canc...
    Speaker: Lindsey M. Costantini, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 03, 2020 | 11:00 AM
    Filtered Fume Hoods: Expert insight on improving your lab's green initiative
    Filtered Fume Hoods: Expert insight on improving your lab's green...
    DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
    Speaker: Kasey Fulmer , Kenneth Crooks
    Sponsored By: Labconco
    11
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