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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
FEB 24, 2021 | 12:00 PM
Stable cell lines are critical tools of cellular assays in drug discovery and development. Over-expressing cell lines are needed to screen for hits, while functional cell lines are needed fo...
FEB 24, 2021 | 12:00 PM
With an introduction by Sarah Warren, the Senior Director of Translational Science, this webinar will open by providing a brief technology overview of NanoString Technologies. Dr. Warren wil...
FEB 24, 2021 | 10:30 AM
Meet xMAP® Technology all over again. Over the past 25 years, Luminex’s xMAP Technology has emerged as the worldwide leader in bead-based multiplexing. The new xMAP® INTELLIFLE...
FEB 24, 2021 | 10:00 AM
DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
FEB 24, 2021 | 7:00 AM
Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
FEB 24, 2021 | 6:00 AM
This webinar will highlight the importance of top-quality starting materials required for consistent, reproducible drug discovery assays. Topics include blood products, the latest in magneti...
FEB 24, 2021 | 6:00 AM
GenScript’s new DNA Encoded Chemical Library (DECL) kit will revolutionize your pharmaceutical hit discovery and chemical biology research. In partnership with a leading technology exp...
FEB 24, 2021 | 12:00 AM
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease affecting approximately 1 in 50,000 people worldwide. About 10% of these cases are found to have a hereditary component, bu...
FEB 24, 2021 | 12:00 AM
G-protein-coupled receptors (GPCRs) remain major drug targets, despite an incomplete understanding of how they signal through 16 non-visual G-protein signal transducers (collectively named t...
