Experimental design is the part of measurements that manages the plan and investigation of examinations. The strategies for test configuration are broadly utilized in the fields of farming, medication, science, showcasing research, and modern creation.
CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
DATE: March 26, 2019TIME: 10:00am PDT, 1:00pm EDT Despite being the most common autoimmune disorder in the United States, knowledge surrounding thyroid di...
Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
Localizing and identifying neuronal patterns that generate pathological brain signals may assist with tissue resection and intervention strategies in patients with neurological and psychiatri...
NIH representatives from the BRAIN Initiative will be presenting an overview of the NIH BRAIN Initiative and describing funding opportunity announcements (FOAs) supporting impacts in human ne...
Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
DATE: December 18, 2018TIME: 10:00am PST, 1:00pm EST Precision medicine anticipates the clinical application of whole-genome sequencing (WGS), as evidenced by the...
DATE: October 30, 2018TIME: 9:00AM PSTMass spectrometry-based proteomics is a rapidly growing area of research that provides useful information for many fields including basi...
DATE: October 18, 2018TIME: 8:00PM PSTExperimental Design Best Practice for Multicolor Flow CytometryMulticolor flow cytometry is a critical technique for many scientific...
DATE: October 18, 2018TIME: 7:00AM PDTExperimental Design Best Practice for Multicolor Flow CytometryMulticolor flow cytometry is a critical technique for many scientific...
Learn how to optimize CRISPR-Cas9 editing efficiencies in cell lines and primary cell types using modified synthetic sgRNA. Includes tips for achieving maximum knockout and knock-in efficienc...
To ensure the immune system’s balance between the recognition of non-self and the prevention of autoimmunity, the activity of immune cells needs to be strictly controlled. During the pr...
The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
Some of the most significant hurdles faced by neuroscientists in the field of neurodegenerative disease research when seeking to acquire genetic information include sample accessibility, repr...
This lecture introduces the evolving paradigm of Molecular Pathological Epidemiology (MPE) as simply as possible. Any given human disease represents fundamentally heterogeneous process,...
We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...
CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
DATE: March 26, 2019TIME: 10:00am PDT, 1:00pm EDT Despite being the most common autoimmune disorder in the United States, knowledge surrounding thyroid di...
Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack o...
Localizing and identifying neuronal patterns that generate pathological brain signals may assist with tissue resection and intervention strategies in patients with neurological and psychiatri...
NIH representatives from the BRAIN Initiative will be presenting an overview of the NIH BRAIN Initiative and describing funding opportunity announcements (FOAs) supporting impacts in human ne...
Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
Over the past 25 years surgically dependent animal models have expanded from a small, almost niche area in pharmaceutical research to an important component of most research portfolios. In t...
DATE: December 18, 2018TIME: 10:00am PST, 1:00pm EST Precision medicine anticipates the clinical application of whole-genome sequencing (WGS), as evidenced by the...
DATE: October 30, 2018TIME: 9:00AM PSTMass spectrometry-based proteomics is a rapidly growing area of research that provides useful information for many fields including basi...
DATE: October 18, 2018TIME: 8:00PM PSTExperimental Design Best Practice for Multicolor Flow CytometryMulticolor flow cytometry is a critical technique for many scientific...
DATE: October 18, 2018TIME: 7:00AM PDTExperimental Design Best Practice for Multicolor Flow CytometryMulticolor flow cytometry is a critical technique for many scientific...
Learn how to optimize CRISPR-Cas9 editing efficiencies in cell lines and primary cell types using modified synthetic sgRNA. Includes tips for achieving maximum knockout and knock-in efficienc...
To ensure the immune system’s balance between the recognition of non-self and the prevention of autoimmunity, the activity of immune cells needs to be strictly controlled. During the pr...
The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
The miniaturized total chemical analysis system has been successfully repurposed over the past twenty years or so for engineering cellular microenvironments which more faithfully mimic in viv...
DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
Some of the most significant hurdles faced by neuroscientists in the field of neurodegenerative disease research when seeking to acquire genetic information include sample accessibility, repr...
This lecture introduces the evolving paradigm of Molecular Pathological Epidemiology (MPE) as simply as possible. Any given human disease represents fundamentally heterogeneous process,...
We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...