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Gene
Gene: is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function.
FEB 05, 2014 | 9:00 AM
Contract Research Organizations present unique challenges in the field of environmental enrichment for laboratory animals. CRO's are service oriented and budget conscious, with large animal p...
FEB 05, 2014 | 9:00 AM
C.E. CREDITS
Public concerns over animal experimentation are becoming felt on both sides of the Atlantic, and a dangerous chasm is appearing between those who conduct such experiments and those who are o...
FEB 05, 2014 | 8:00 AM
The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
FEB 05, 2014 | 7:00 AM
C.E. CREDITS
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
FEB 05, 2014 | 6:00 AM
C.E. CREDITS
This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
NOV 08, 2013 | 12:00 PM
The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
OCT 17, 2013 | 2:00 PM
C.E. CREDITS
Pancreatic cancer is the 4th most common cause of cancer deaths in the United States. Due to the aggressive nature of this cancer and the lack of biomarkers for early detection, the incidence...
OCT 17, 2013 | 10:00 AM
C.E. CREDITS
Prostate cancer epithelial cells depend on androgens for their survival. Because of this dependence, androgen deprivation therapy is the major treatment of advanced prostate cancer. Such ther...
OCT 17, 2013 | 9:00 AM
C.E. CREDITS
Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
OCT 17, 2013 | 9:00 AM
DNASTAR offers an integrated suite of software for assembling and analyzing data from all major next-generation sequencing platforms. The software supports a variety of reference guided and d...
OCT 17, 2013 | 7:00 AM
Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
OCT 17, 2013 | 7:00 AM
RNA-Seq allows the simultaneous observation of gene expression levels, mutations in the coding sequences, splice variants and gene fusions, which are especially important in cancer studies. A...
OCT 17, 2013 | 6:00 AM
The widespread adoption of precision medicine in oncology requires: a compendium of therapies targeting the genetic vulnerabilities of cancer; the diagnostic tools capable of generating a pr...
OCT 16, 2013 | 3:00 PM
C.E. CREDITS
While Melanoma is very curable and treatable when detected early, late stage melanoma has had a very poor outcome. In 2013, it is estimated that over 80,000 patients in the US will develop me...
OCT 16, 2013 | 3:00 PM
C.E. CREDITS
Deregulation of ACK1, a non-receptor tyrosine kinase originally identified by its ability to bind to GTP-bound Cdc42 (hence the name: activated Cdc42-associated kinase)(Manser et al., 1993),...
OCT 16, 2013 | 1:00 PM
C.E. CREDITS
The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
OCT 16, 2013 | 1:00 PM
C.E. CREDITS
While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
OCT 16, 2013 | 1:00 PM
C.E. CREDITS
Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
OCT 16, 2013 | 12:00 PM
The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
OCT 16, 2013 | 11:00 AM
Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
OCT 16, 2013 | 9:00 AM
C.E. CREDITS
It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
OCT 16, 2013 | 7:00 AM
Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of can...