Immunity: is the balanced state of multicellular organisms having adequate biological defenses to fight infection, disease, or other unwanted biological invasion, while having adequate tolerance to avoid allergy, and autoimmune diseases.
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Accurate and timely diagnosis of inborn errors of immunity (IEI) is essential for improving patient outcomes. Flow cytometry is widely recommended for robust and sensitive IEI screening; how...
Immunotherapy has transformed cancer treatment, but persistent challenges, such as T cell exhaustion, limited persistence, and variability in response, continue to impact therapeutic success...
OCT 01, 2025 | 7:30 AM
C.E. CREDITS
Non-small cell lung cancer (NSCLC) accounts for more deaths than colon, breast, and prostate cancers combined. Of patients with NSCLC, 20% initially present with stage I or II disease, for w...
Effective functioning of the immune system relies upon systems of checks and balances; too little activity results in overwhelming infection, too much activity results in excessive damage to...
Join Dr. Krista Rantanen for an inside look at the unique challenges of cultivating anaerobic and microaerophilic bacteria. This session will explore why controlling oxygen levels is essenti...
The HIV-1 Nef accessory factor promotes viral replication and immune escape of HIV-infected cells, making it an attractive drug target. Our team previously identified small molecules that bi...
Antibodies are a major component of adaptive immunity against invading pathogens. In this presentation, we will describe an analytical approach to characterize the antigen-specific antibody...
Single-cell analysis is a new and rapidly growing field that is shedding new insight into the cellular mechanisms behind the pathogenesis and treatment of infectious diseases and cancer. Cel...
Expression of co-inhibitory receptors or “checkpoint” molecules, such as CTLA-4 and PD-1, on effector T cells is a key mechanism for ensuring immune homeostasis. Dysregulated exp...
Immunotherapy has changed the landscape of oncology, improving survival rates for many patients across a variety of malignancies. Two antibody-based immunotherapies, immune checkpoint inhibi...
Human inborn errors of immunity (IEI) comprise a variety of diseases caused by molecular variants that impair both innate and adaptive immune responses. Patients with IEI often exhibit a sus...
In light of the numerous US FDA-approved humanized monoclonal antibodies (mAbs) for cancer immunotherapy, it is surprising that the advancement of B-cell epitope vaccines designed to elicit...
Brain cancer research stands to benefit from the perspectives, tools, and methodologies of non-traditional fields, such as mechanical engineering. Here, I will discuss our engineering-based...