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    In Vivo

    In Vivo: are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

    Webinars

    • SEP 23, 2020 | 10:30 AM
      Practical Mass Cytometry
      Practical Mass Cytometry
      On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
      Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 23, 2020 | 9:00 AM
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Keynote Presentation: Extracellular vesicles in Regenerative Medicine
      Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
      Speaker: Benedetta Bussolati, MD, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      2
      SEP 23, 2020 | 12:00 AM
      The role of Nox-derived Reactive Oxygen Species in Axonal Growth and Guidance
      The role of Nox-derived Reactive Oxygen Species in Axonal Growth...
      Reactive oxygen species (ROS) are well-known for their detrimental effects leading to oxidative stress, cell death, aging, and degenerative disorders. However, there is increasing evidence t...
      Speaker: Daniel M. Suter, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      2
      SEP 23, 2020 | 12:00 AM
      Clinical Scale production extracellular vesicles from various cell types in a cGMP compatible 3-D Capillary Bioreactor: from culture dish to 3-D capillary bioreactor
      Clinical Scale production extracellular vesicles from various...
      Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
      Speaker: John J.S. Cadwell
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      Extracellular Vesicles and Chronic Kidney Disease
      Extracellular Vesicles and Chronic Kidney Disease
      Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
      Speaker: Sargis Sedrakyan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 10, 2020 | 1:00 PM
      Keynote Presentation: Evolution of host-specific virulence in an RNA virus of Pacific salmonid fish
      Keynote Presentation: Evolution of host-specific virulence in...
      In Pacific Northwest watersheds several species of Pacific salmonid fishes are hosts for the rhabdovirus infectious hematopoietic necrosis virus (IHNV). In this multi-host ecosystem speciali...
      Speaker: Gael Kurath, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 09, 2020 | 12:00 AM
      Fc gamma receptor activation during viral infections: a double-edged sword
      Fc gamma receptor activation during viral infections: a double-edged...
      Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
      Speaker: Raymond A. Alvarez, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Lung immune cells as drivers of influenza outcomes
      Lung immune cells as drivers of influenza outcomes
      Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
      Speaker: Juliet Morrison, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      AUG 06, 2020 | 10:00 AM
      Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      Part VII: From biochemical nanosensors to imaging to informatics...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 10:00 AM
      Part VI: Dissecting Cell Signaling Networks That Regulate Adult Neural Stem Cell Functions
      Part VI: Dissecting Cell Signaling Networks That Regulate Adult...
      In the adult mammalian hippocampus, neurogenesis (in which new neurons are generated and integrated into the CNS) is believed to underlie learning and memory. Within the hippocampus, numerou...
      Speaker: Kira Mosher, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 10:00 AM
      Part IV: SPARC - A method to genetically manipulate precise proportions of cells
      Part IV: SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      2
      AUG 06, 2020 | 10:00 AM
      Part II: Extracting Photochemical Design Principles from Biological Systems in vivo
      Part II: Extracting Photochemical Design Principles from Biological...
      Natural light-harvesting systems, such as photosynthetic pigment-protein complexes, efficiently transfer energy through space with high efficiency. Ultimately, we would like to understand th...
      Speaker: Marco Allodi, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      From biochemical nanosensors to imaging to informatics to COVID-19...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
      Causes and consequences of rapid cancer cell adaptation to therapeutic...
      Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
      Speaker: Sabrina Spencer, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      SPARC - A method to genetically manipulate precise proportions of cells
      SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 29, 2020 | 5:00 PM
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
      Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 4:00 PM
      Measuring Immune Cell Killing Dynamics through Real Time Impedance and Live Cell Imaging
      Measuring Immune Cell Killing Dynamics through Real Time Impedance...
      The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
      Speaker: Fabio Cerignoli, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2 1
      JUL 29, 2020 | 2:00 PM
      Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
      Route of 41BB/41BBL costimulation determines effector function...
      B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
      Speaker: Christopher DeRenzo, MD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 12:00 PM
      Linking Cancer Metabolism to Neurodegeneration
      Linking Cancer Metabolism to Neurodegeneration
      The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
      Speaker: Navdeep S. Chandel PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      3
      JUL 29, 2020 | 11:00 AM
      STAT3 phosphorylation during phagocytosis is required to activate autophagy and prevent macrophage immuno-senescence
      STAT3 phosphorylation during phagocytosis is required to activate...
      Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
      Speaker: Lara Campana, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 12:00 AM
      3D Culture Methods and Imaging Considerations
      3D Culture Methods and Imaging Considerations
      The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
      Speaker: Brad Larson , Valerie Sodi, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
    SEP 23, 2020 | 10:30 AM
    Practical Mass Cytometry
    Practical Mass Cytometry
    On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
    Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    SEP 23, 2020 | 9:00 AM
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Keynote Presentation: Extracellular vesicles in Regenerative Medicine
    Extracellular vesicles (EVs) are nanosized vesicles containing active proteins, lipids, and different types of genetic material such as non coding RNA species, related to the characteristics...
    Speaker: Benedetta Bussolati, MD, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    2
    SEP 23, 2020 | 12:00 AM
    The role of Nox-derived Reactive Oxygen Species in Axonal Growth and Guidance
    The role of Nox-derived Reactive Oxygen Species in Axonal Growth...
    Reactive oxygen species (ROS) are well-known for their detrimental effects leading to oxidative stress, cell death, aging, and degenerative disorders. However, there is increasing evidence t...
    Speaker: Daniel M. Suter, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    2
    SEP 23, 2020 | 12:00 AM
    Clinical Scale production extracellular vesicles from various cell types in a cGMP compatible 3-D Capillary Bioreactor: from culture dish to 3-D capillary bioreactor
    Clinical Scale production extracellular vesicles from various...
    Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
    Speaker: John J.S. Cadwell
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 12:00 AM
    Extracellular Vesicles and Chronic Kidney Disease
    Extracellular Vesicles and Chronic Kidney Disease
    Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
    Speaker: Sargis Sedrakyan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
     
     
  • SEP 10, 2020 | 1:00 PM
    Keynote Presentation: Evolution of host-specific virulence in an RNA virus of Pacific salmonid fish
    Keynote Presentation: Evolution of host-specific virulence in...
    In Pacific Northwest watersheds several species of Pacific salmonid fishes are hosts for the rhabdovirus infectious hematopoietic necrosis virus (IHNV). In this multi-host ecosystem speciali...
    Speaker: Gael Kurath, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 09, 2020 | 12:00 AM
    Fc gamma receptor activation during viral infections: a double-edged sword
    Fc gamma receptor activation during viral infections: a double-edged...
    Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
    Speaker: Raymond A. Alvarez, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    Lung immune cells as drivers of influenza outcomes
    Lung immune cells as drivers of influenza outcomes
    Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
    Speaker: Juliet Morrison, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
     
     
  • AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
    AUG 06, 2020 | 10:00 AM
    Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    Part VII: From biochemical nanosensors to imaging to informatics...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 10:00 AM
    Part VI: Dissecting Cell Signaling Networks That Regulate Adult Neural Stem Cell Functions
    Part VI: Dissecting Cell Signaling Networks That Regulate Adult...
    In the adult mammalian hippocampus, neurogenesis (in which new neurons are generated and integrated into the CNS) is believed to underlie learning and memory. Within the hippocampus, numerou...
    Speaker: Kira Mosher, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 10:00 AM
    Part IV: SPARC - A method to genetically manipulate precise proportions of cells
    Part IV: SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    2
    AUG 06, 2020 | 10:00 AM
    Part II: Extracting Photochemical Design Principles from Biological Systems in vivo
    Part II: Extracting Photochemical Design Principles from Biological...
    Natural light-harvesting systems, such as photosynthetic pigment-protein complexes, efficiently transfer energy through space with high efficiency. Ultimately, we would like to understand th...
    Speaker: Marco Allodi, PhD
    Presented at: 2020 Beckman Symposium
    1
     
     
  • AUG 06, 2020 | 12:00 AM
    From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    From biochemical nanosensors to imaging to informatics to COVID-19...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
    Causes and consequences of rapid cancer cell adaptation to therapeutic...
    Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
    Speaker: Sabrina Spencer, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    SPARC - A method to genetically manipulate precise proportions of cells
    SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 29, 2020 | 5:00 PM
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
    Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 4:00 PM
    Measuring Immune Cell Killing Dynamics through Real Time Impedance and Live Cell Imaging
    Measuring Immune Cell Killing Dynamics through Real Time Impedance...
    The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
    Speaker: Fabio Cerignoli, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2 1
     
     
  • JUL 29, 2020 | 2:00 PM
    Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
    Route of 41BB/41BBL costimulation determines effector function...
    B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
    Speaker: Christopher DeRenzo, MD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 12:00 PM
    Linking Cancer Metabolism to Neurodegeneration
    Linking Cancer Metabolism to Neurodegeneration
    The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
    Speaker: Navdeep S. Chandel PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    3
    JUL 29, 2020 | 11:00 AM
    STAT3 phosphorylation during phagocytosis is required to activate autophagy and prevent macrophage immuno-senescence
    STAT3 phosphorylation during phagocytosis is required to activate...
    Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
    Speaker: Lara Campana, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 12:00 AM
    3D Culture Methods and Imaging Considerations
    3D Culture Methods and Imaging Considerations
    The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
    Speaker: Brad Larson , Valerie Sodi, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
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