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    Medicine

    Medicine: the science or practice of the diagnosis, treatment, and prevention of disease (in technical use often taken to exclude surgery).

    Webinars

    • OCT 30, 2014 | 10:30 AM
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool for Optimizing Drug Management
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool...
      Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
      Speaker: William Clarke, PhD, MBA, DABCC
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 30, 2014 | 10:30 AM
      Development of molecularly targeted imaging agents and identification of novel targets in cancer
      Development of molecularly targeted imaging agents and identification...
      The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
      Speaker: Kimberly Kelly , PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 10:30 AM
      Genomics in the Clinic: Promises and Challenges
      Genomics in the Clinic: Promises and Challenges
      Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
      Speaker: John Carpten, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 9:00 AM
      A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
      A head-to-head comparison of whole blood derived samples (cfDNA...
      Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
      Speaker: Paul W. Dempsey, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 30, 2014 | 6:00 AM
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
      When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      8
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 3:00 PM
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
      Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
      Speaker: Peter Blume-Jensen, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 1:30 PM
      Metabolic therapy for the adjuvant treatment of malignant brain tumors
      Metabolic therapy for the adjuvant treatment of malignant brain...
      Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
      Speaker: Adrienne C. Scheck, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 1:30 PM
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      PDX Tumor Models for Oncology Research and Preclinical Prediction
      Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
      Speaker: Walter Ausserer, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      50
      OCT 29, 2014 | 12:00 PM
      Obesity, weight loss, and the microenvironment in basal-like breast cancer
      Obesity, weight loss, and the microenvironment in basal-like breast...
      Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
      Speaker: Liza Makowski, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 12:00 PM
      Improving the Robustness and Reproducibility of Quantitative Proteomics
      Improving the Robustness and Reproducibility of Quantitative Proteomics
      Proteomics technology has improved dramatically over the last decade. The technology developments have largely been directed around instrument hardware, where instruments have been developed...
      Speaker: Michael MacCoss, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 10:30 AM
      Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
      Learning from the Pointillists - Using Big Data Approaches to...
      The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 29, 2014 | 9:00 AM
      Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
      Reading and disrupting the histone code with chemical agents:...
      Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
      Speaker: Fraser Hof, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      7
      OCT 29, 2014 | 9:00 AM
      What's wrong with biomarker development for cancer
      What's wrong with biomarker development for cancer
      Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
      Speaker: Anna Barker, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 29, 2014 | 9:00 AM
      miRNA Biomarker Discovery: Technologies, workflows, and data analysis solutions for discovering your unique signature
      miRNA Biomarker Discovery: Technologies, workflows, and data analysis...
      Circulating miRNAs have great potential as biomarkers due to their aberrant expression in cancer and other diseases. However, miRNAs from body fluids are hard to obtain in amounts sufficient...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      18
      OCT 29, 2014 | 7:30 AM
      Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
      Targeting the oncogene eIF4E in leukemia reveals a new form of...
      The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
      Speaker: Katherine LB Borden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      40
      OCT 29, 2014 | 6:00 AM
      Expanding the scope of RNA-Seq to archival FFPE samples
      Expanding the scope of RNA-Seq to archival FFPE samples
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett, M.S.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      4
      OCT 29, 2014 | 6:00 AM
      Nanotechnologies for Precision Medicine
      Nanotechnologies for Precision Medicine
      The modern era of Precision Medicine requires targeted delivery of molecular inhibitors that control key processes in disease pathways. PARP (Poly ADP Ribose Polymerase) plays a crucial role...
      Speaker: Srinivas (Sri) Sridhar, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      65
      OCT 24, 2014 | 12:00 PM
      What to Do About Flu in 2014
      What to Do About Flu in 2014
        Influenza is a major clinical and public health issue.  Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
      Speaker: Sheldon Campbell M.D. Ph.D. F.C.A.P.
      Sponsored By: Alere, Alere
      36
      OCT 16, 2014 | 8:00 AM
      Comprehensive Anti-doping Detection using the Q Exactive Orbitrap MS for Equine Urine Analysis
      Comprehensive Anti-doping Detection using the Q Exactive Orbitrap...
       Equine anti-doping analysis is a changing and dynamic field of science. The constant introduction of new drugs and biopharmaceuticals present challenges to the integrity of sports. Anti-dopi...
      Speaker: Scott D Stanley, PhD
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      26
      SEP 24, 2014 | 2:00 PM
      Development and Applications of CRISPR-Cas9 for Genome Editing
      Development and Applications of CRISPR-Cas9 for Genome Editing
      The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
      Speaker: Feng Zhang, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      39
      SEP 24, 2014 | 2:00 PM
      Targeting Lysine Acetylation in Cancer
      Targeting Lysine Acetylation in Cancer
      Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
      Speaker: Jay Bradner, MD
      Presented at: Advances in Drug Discovery and Development
      18
      SEP 24, 2014 | 12:00 PM
      Exploiting cell death for drug discovery
      Exploiting cell death for drug discovery
      Professor Stockwell will discuss the discovery of ferroptosis, a novel model of regulated but non-apoptotic cell death. He will describe how some tumors are sensitized to ferroptosis and may...
      Speaker: Brent Stockwell, PhD
      Presented at: Advances in Drug Discovery and Development
      22
      SEP 24, 2014 | 11:00 AM
      Structure based Drug Design for G-protein coupled receptors using the StaR(r) technology
      Structure based Drug Design for G-protein coupled receptors using...
      Heptares Therapeutics is a structure based drug discovery and development company which uses it StaR technology to enable X-ray structures, fragment screening and other biophysical techniques...
      Speaker: Fiona Marshall, PhD
      Presented at: Advances in Drug Discovery and Development
      10
    OCT 30, 2014 | 10:30 AM
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool for Optimizing Drug Management
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool...
    Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
    Speaker: William Clarke, PhD, MBA, DABCC
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 30, 2014 | 10:30 AM
    Development of molecularly targeted imaging agents and identification of novel targets in cancer
    Development of molecularly targeted imaging agents and identification...
    The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
    Speaker: Kimberly Kelly , PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 10:30 AM
    Genomics in the Clinic: Promises and Challenges
    Genomics in the Clinic: Promises and Challenges
    Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
    Speaker: John Carpten, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 9:00 AM
    A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
    A head-to-head comparison of whole blood derived samples (cfDNA...
    Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
    Speaker: Paul W. Dempsey, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
    OCT 30, 2014 | 6:00 AM
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
    When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    8
     
     
  • OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 3:00 PM
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
    Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
    Speaker: Peter Blume-Jensen, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
    OCT 29, 2014 | 1:30 PM
    Metabolic therapy for the adjuvant treatment of malignant brain tumors
    Metabolic therapy for the adjuvant treatment of malignant brain...
    Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
    Speaker: Adrienne C. Scheck, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 29, 2014 | 1:30 PM
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    PDX Tumor Models for Oncology Research and Preclinical Prediction
    Patient-derived xenograft (PDX) models can recapitulate patient tumor histopathology, mutational status, gene expression patterns, and drug response with remarkable fidelity. At The Jackson L...
    Speaker: Walter Ausserer, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    50
    OCT 29, 2014 | 12:00 PM
    Obesity, weight loss, and the microenvironment in basal-like breast cancer
    Obesity, weight loss, and the microenvironment in basal-like breast...
    Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
    Speaker: Liza Makowski, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
     
     
  • OCT 29, 2014 | 12:00 PM
    Improving the Robustness and Reproducibility of Quantitative Proteomics
    Improving the Robustness and Reproducibility of Quantitative Proteomics
    Proteomics technology has improved dramatically over the last decade. The technology developments have largely been directed around instrument hardware, where instruments have been developed...
    Speaker: Michael MacCoss, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 29, 2014 | 10:30 AM
    Learning from the Pointillists - Using Big Data Approaches to Embrace the Complexity of Cancer
    Learning from the Pointillists - Using Big Data Approaches to...
    The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 29, 2014 | 9:00 AM
    Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
    Reading and disrupting the histone code with chemical agents:...
    Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
    Speaker: Fraser Hof, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    7
    OCT 29, 2014 | 9:00 AM
    What's wrong with biomarker development for cancer
    What's wrong with biomarker development for cancer
    Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
    Speaker: Anna Barker, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 29, 2014 | 9:00 AM
    miRNA Biomarker Discovery: Technologies, workflows, and data analysis solutions for discovering your unique signature
    miRNA Biomarker Discovery: Technologies, workflows, and data analysis...
    Circulating miRNAs have great potential as biomarkers due to their aberrant expression in cancer and other diseases. However, miRNAs from body fluids are hard to obtain in amounts sufficient...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    18
     
     
  • OCT 29, 2014 | 7:30 AM
    Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
    Targeting the oncogene eIF4E in leukemia reveals a new form of...
    The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
    Speaker: Katherine LB Borden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    40
    OCT 29, 2014 | 6:00 AM
    Expanding the scope of RNA-Seq to archival FFPE samples
    Expanding the scope of RNA-Seq to archival FFPE samples
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett, M.S.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    4
    OCT 29, 2014 | 6:00 AM
    Nanotechnologies for Precision Medicine
    Nanotechnologies for Precision Medicine
    The modern era of Precision Medicine requires targeted delivery of molecular inhibitors that control key processes in disease pathways. PARP (Poly ADP Ribose Polymerase) plays a crucial role...
    Speaker: Srinivas (Sri) Sridhar, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    65
    OCT 24, 2014 | 12:00 PM
    What to Do About Flu in 2014
    What to Do About Flu in 2014
      Influenza is a major clinical and public health issue.  Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
    Speaker: Sheldon Campbell M.D. Ph.D. F.C.A.P.
    Sponsored By: Alere, Alere
    36
    OCT 16, 2014 | 8:00 AM
    Comprehensive Anti-doping Detection using the Q Exactive Orbitrap MS for Equine Urine Analysis
    Comprehensive Anti-doping Detection using the Q Exactive Orbitrap...
     Equine anti-doping analysis is a changing and dynamic field of science. The constant introduction of new drugs and biopharmaceuticals present challenges to the integrity of sports. Anti-dopi...
    Speaker: Scott D Stanley, PhD
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    26
     
     
  • SEP 24, 2014 | 2:00 PM
    Development and Applications of CRISPR-Cas9 for Genome Editing
    Development and Applications of CRISPR-Cas9 for Genome Editing
    The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
    Speaker: Feng Zhang, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    39
    SEP 24, 2014 | 2:00 PM
    Targeting Lysine Acetylation in Cancer
    Targeting Lysine Acetylation in Cancer
    Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
    Speaker: Jay Bradner, MD
    Presented at: Advances in Drug Discovery and Development
    18
    SEP 24, 2014 | 12:00 PM
    Exploiting cell death for drug discovery
    Exploiting cell death for drug discovery
    Professor Stockwell will discuss the discovery of ferroptosis, a novel model of regulated but non-apoptotic cell death. He will describe how some tumors are sensitized to ferroptosis and may...
    Speaker: Brent Stockwell, PhD
    Presented at: Advances in Drug Discovery and Development
    22
    SEP 24, 2014 | 11:00 AM
    Structure based Drug Design for G-protein coupled receptors using the StaR(r) technology
    Structure based Drug Design for G-protein coupled receptors using...
    Heptares Therapeutics is a structure based drug discovery and development company which uses it StaR technology to enable X-ray structures, fragment screening and other biophysical techniques...
    Speaker: Fiona Marshall, PhD
    Presented at: Advances in Drug Discovery and Development
    10
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