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    Method optimization

    In medical research, method optimization evaluates ways to minimize or maximize specific parameters of a study. Optimization can involve parameters such as reducing the costs associated with a procedure, limiting the materials required to develop an assay, or obtaining maximal productivity from a technique.

    Webinars

    • OCT 05, 2016 | 6:00 AM
      Unique molecular indices (UMI) and their application in detecting novel gene fusions and gene expression and genetic variation
      Unique molecular indices (UMI) and their application in detecting...
      Tumor heterogeneity has been known for a while but quantifying heterogeneity is still a challenge.  NGS is the method of choice in the analysis of tumor heterogeneity, however, there are...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      3
      SEP 13, 2016 | 12:30 PM
      Defining Best Practices for Urinalysis Diagnostics in a Value-Based Healthcare System
      Defining Best Practices for Urinalysis Diagnostics in a Value-Based...
      Urinalysis is one the oldest, most established, and most frequently ordered laboratory tests.  However, there is wide variation in the methods, processes, quality checks, specifications,...
      Speaker: Tim Skelton
      Presented at: A Virtual Destination for Laboratory Professionals
      Sponsored By: Cardinal Healthâ„¢ OptiFreight® Logistics, ARKRAY
      7
      JUL 26, 2016 | 7:30 AM
      Automated assays for protein engineering: in vitro and in vivo
      Automated assays for protein engineering: in vitro and in vivo
      Enzyme engineering is a powerful technology now widely used in laboratories around the world. The goal is to obtain improved proteins that will serve as better biocatalysts, biosensors or as ...
      Speaker: Daniela Quaglia, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      10 2
      JUN 29, 2016 | 7:30 AM
      Charge Heterogeneity Analysis of Biologics by Capillary Isoelectric Focusing (cIEF) and Capillary Zone Electrophoresis (CZE)
      Charge Heterogeneity Analysis of Biologics by Capillary Isoelectric...
           Implementation of Capillary Electrophoresis (CE) technology in the biopharmaceutical industry is helping to characterize purity, heterogeneity, and identity of therapeutic...
      Speaker: Brandon Bates
      Sponsored By: Sciex, Sciex
      2
      JUN 28, 2016 | 7:00 AM
      Chemistry and technology advancements in protein gel electrophoresis
      Chemistry and technology advancements in protein gel electrophoresis
      For many years, the Laemmli system has been the standard and most popular method used to perform polyacrylamide gel electrophoresis. Laemmli type gels are useful for a broad range of protein...
      Speaker: Jun Ma
      Presented at: Protein and Cell Analysis Education Series
      5
      JUN 23, 2016 | 11:00 AM
      Spotlights on T cells: new developments for translational and basic T cell research
      Spotlights on T cells: new developments for translational and...
      DATE:  June 23, 2016 TIME:  11:00am Pacific time, 2:00pm Eastern time T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
      Speaker: Anne Richter, PhD
      Sponsored By: Miltenyi Biotec, Miltenyi Biotec
      6 1
      JUN 14, 2016 | 8:00 AM
      Rethinking the timeline required for Quality by Design studies in protein process development
      Rethinking the timeline required for Quality by Design studies...
      DATE: June 14, 2016TIME:  8am Pacific time, 11am Eastern timeImproving systems for rapid small-scale protein purification and analysis in order to obtain sample numbers for statist...
      Speaker: Louis Fabri , Bill Flaherty
      Sponsored By: Revvity
      15
      MAY 24, 2016 | 8:00 AM
      Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
      Implement high-throughput 3D image analysis for samples from subcellular...
      DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
      Speaker: Oksana Sirenko, PhD , Steven Luke
      Sponsored By: Molecular Devices, Molecular Devices
      7 1
      MAY 12, 2016 | 10:30 AM
      Antha: An Operating System for Seamlessly Linking Experimental Design and Lab Automation
      Antha: An Operating System for Seamlessly Linking Experimental...
      Working with biology currently takes too long, costs too much, and fails too often. At the core of this is the complexity of the systems we are trying to understand, compounded by a lack of r...
      Speaker: Sean Ward
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 12, 2016 | 10:30 AM
      DNA methylation analysis by multiplexed reduced representation bisulfite sequencing
      DNA methylation analysis by multiplexed reduced representation...
      DNA methylation is an essential mechanism of epigenetic gene regulation with broad relevance in development and disease. Its localization on genomic DNA and general stability make this epigen...
      Speaker: Paul Datlinger
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      APR 04, 2016 | 8:00 AM
      Phage Antibody Selection on the Reichert SR7500DC SPR System
      Phage Antibody Selection on the Reichert SR7500DC SPR System
      DATE: April 4, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time The use of surface plasmon resonance to characterize protein:protein interactions is well established and has bee...
      Speaker: Mark Sullivan, Ph.D.
      Sponsored By: Ametek, Ametek
      9
      MAR 31, 2016 | 8:00 AM
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
      DATE:  March 31, 2016 TIME:   8am PT, 11am ET, 4pm GMT In this webinar, you will learn:  Basics of homology-directed repair (HDR) using CRISPR-Cas9 Selection of CRISP...
      Speaker: John Schiel, Ph.D.
      Sponsored By: Dharmacon, Dharmacon
      31 12
      MAR 17, 2016 | 9:00 AM
      Featured Speaker - The neurobiology underlying drug addiction: lessons from multimodality imaging and neuropsychological studies in humans
      Featured Speaker - The neurobiology underlying drug addiction:...
      Drug addiction is a chronically relapsing disorder characterized by compulsive drug use despite catastrophic personal consequences (e.g., loss of family, job) and even when the substance is n...
      Speaker: Rita Goldstein, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      2
      MAR 10, 2016 | 8:00 AM
      Fully Automated, One Hour Sample Preparation for Ultrafast N-Glycosylation Analysis of Antibody Therapeutics
      Fully Automated, One Hour Sample Preparation for Ultrafast N-Glycosylation...
      DATE: March 10, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time SCIEX has recently introduced an easy-to-use magnetic bead based sample preparation workflow, enabling the prepa...
      Speaker: Andras Guttman, PhD
      Sponsored By: Sciex, Sciex
      9
      FEB 04, 2016 | 6:00 AM
      Zebrafish: an upswing model in research and the need for refinement of anaesthesia
      Zebrafish: an upswing model in research and the need for refinement...
           In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
      Speaker: Ana Valentim, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 04, 2016 | 6:00 AM
      Steps on the route to optimising experimental design, including teaching and conducting systematic reviews
      Steps on the route to optimising experimental design, including...
      A number of elements come into the mix when trying to optimise experimental design. Among these are having clear objectives, setting up valid comparisons, knowing how to avoid bias during the...
      Speaker: Derek Fry OBE, MA, D Phil, MB BCh , Rob de Vries, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 03, 2016 | 1:30 PM
      In-house development and implementation of surgical animal models
      In-house development and implementation of surgical animal models
      Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      3
      DEC 09, 2015 | 8:00 AM
      Moisture Analysis in Pharma: Expanding Near-Infrared Spectroscopy with Karl Fischer Titration
      Moisture Analysis in Pharma: Expanding Near-Infrared Spectroscopy...
      DATE: December 9, 2015 TIME: 8am Pacific, 11am Eastern Pharmaceutical product quality, effectiveness and shelf life depends significantly on the water content in these products, which mak...
      Speaker: Joseph Head, MS , Keith Freel, PhD
      Sponsored By: Metrohm USA, Metrohm USA
      4
      NOV 24, 2015 | 6:00 AM
      Say goodbye to Gels - Real world use of LabChip micro-fluidic technology for nucleic acid and protein analysis
      Say goodbye to Gels - Real world use of LabChip micro-fluidic...
      DATE: November 24, 2015TIME: 9am EST, 2pm GMTFor many years now, gels have been a fundamental research tool in academic research for the separation and analysis of nucleic acids and pro...
      Speaker: Julius Kostan, PhD , Sandra Doran , Veronika Delcheva
      Sponsored By: Revvity
      29
      NOV 12, 2015 | 10:30 AM
      Pharmacogenetics in the Clinical Laboratory: Opportunities and Challenges
      Pharmacogenetics in the Clinical Laboratory: Opportunities and...
      Appropriate dosing of pharmaceuticals is critical to prevent sub-therapeutic efficacy or the occurrence of adverse events. However, genetic variability may significantly influence an individu...
      Speaker: Allison Chambliss, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      4
      NOV 12, 2015 | 7:30 AM
      Keynote: Reconceptualizing Genital Herpes Diagnosis and Management
      Keynote: Reconceptualizing Genital Herpes Diagnosis and Management
      As one of the nation's most prevalent sexually transmitted infections, genital herpes represents a diagnostic and therapeutic challenge to clinicians, laboratorians and the patients they...
      Speaker: Edward Hook, III, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      2 1
      NOV 11, 2015 | 6:00 AM
      A Comprehensive Toxicology Screening Solution Targeted to Individual Needs
      A Comprehensive Toxicology Screening Solution Targeted to Individual...
      Drugs of abuse toxicology testing by immunoassays is widely used clinically, but also known to be inadequate for many clinical indications. In this presentation, the speaker will outline diff...
      Speaker: Ping Wang, PhD, DABCC, FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      3
      NOV 11, 2015 | 6:00 AM
      Clinical next-generation sequencing for precision cancer therapeutics
      Clinical next-generation sequencing for precision cancer therapeutics
      Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
      Speaker: Christina (Tina) Lockwood, PhD, DABCC, FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      2
      OCT 15, 2015 | 7:30 AM
      WEBINAR: Graduate from Shaker to Fermentor
      WEBINAR: Graduate from Shaker to Fermentor
      DATE: October 15, 2015 TIME: 7:30AM PDT, 10:30AM EDT Most cell biologists culture cells in dishes and shake flasks to produce proteins and biological molecules; however the production of ...
      Speaker: Michelet Dorceus
      Sponsored By: Eppendorf, Eppendorf
      8 1
    OCT 05, 2016 | 6:00 AM
    Unique molecular indices (UMI) and their application in detecting novel gene fusions and gene expression and genetic variation
    Unique molecular indices (UMI) and their application in detecting...
    Tumor heterogeneity has been known for a while but quantifying heterogeneity is still a challenge.  NGS is the method of choice in the analysis of tumor heterogeneity, however, there are...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    3
    SEP 13, 2016 | 12:30 PM
    Defining Best Practices for Urinalysis Diagnostics in a Value-Based Healthcare System
    Defining Best Practices for Urinalysis Diagnostics in a Value-Based...
    Urinalysis is one the oldest, most established, and most frequently ordered laboratory tests.  However, there is wide variation in the methods, processes, quality checks, specifications,...
    Speaker: Tim Skelton
    Presented at: A Virtual Destination for Laboratory Professionals
    Sponsored By: Cardinal Healthâ„¢ OptiFreight® Logistics, ARKRAY
    7
    JUL 26, 2016 | 7:30 AM
    Automated assays for protein engineering: in vitro and in vivo
    Automated assays for protein engineering: in vitro and in vivo
    Enzyme engineering is a powerful technology now widely used in laboratories around the world. The goal is to obtain improved proteins that will serve as better biocatalysts, biosensors or as ...
    Speaker: Daniela Quaglia, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    10 2
    JUN 29, 2016 | 7:30 AM
    Charge Heterogeneity Analysis of Biologics by Capillary Isoelectric Focusing (cIEF) and Capillary Zone Electrophoresis (CZE)
    Charge Heterogeneity Analysis of Biologics by Capillary Isoelectric...
         Implementation of Capillary Electrophoresis (CE) technology in the biopharmaceutical industry is helping to characterize purity, heterogeneity, and identity of therapeutic...
    Speaker: Brandon Bates
    Sponsored By: Sciex, Sciex
    2
    JUN 28, 2016 | 7:00 AM
    Chemistry and technology advancements in protein gel electrophoresis
    Chemistry and technology advancements in protein gel electrophoresis
    For many years, the Laemmli system has been the standard and most popular method used to perform polyacrylamide gel electrophoresis. Laemmli type gels are useful for a broad range of protein...
    Speaker: Jun Ma
    Presented at: Protein and Cell Analysis Education Series
    5
     
     
  • JUN 23, 2016 | 11:00 AM
    Spotlights on T cells: new developments for translational and basic T cell research
    Spotlights on T cells: new developments for translational and...
    DATE:  June 23, 2016 TIME:  11:00am Pacific time, 2:00pm Eastern time T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
    Speaker: Anne Richter, PhD
    Sponsored By: Miltenyi Biotec, Miltenyi Biotec
    6 1
    JUN 14, 2016 | 8:00 AM
    Rethinking the timeline required for Quality by Design studies in protein process development
    Rethinking the timeline required for Quality by Design studies...
    DATE: June 14, 2016TIME:  8am Pacific time, 11am Eastern timeImproving systems for rapid small-scale protein purification and analysis in order to obtain sample numbers for statist...
    Speaker: Louis Fabri , Bill Flaherty
    Sponsored By: Revvity
    15
    MAY 24, 2016 | 8:00 AM
    Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
    Implement high-throughput 3D image analysis for samples from subcellular...
    DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
    Speaker: Oksana Sirenko, PhD , Steven Luke
    Sponsored By: Molecular Devices, Molecular Devices
    7 1
    MAY 12, 2016 | 10:30 AM
    Antha: An Operating System for Seamlessly Linking Experimental Design and Lab Automation
    Antha: An Operating System for Seamlessly Linking Experimental...
    Working with biology currently takes too long, costs too much, and fails too often. At the core of this is the complexity of the systems we are trying to understand, compounded by a lack of r...
    Speaker: Sean Ward
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 12, 2016 | 10:30 AM
    DNA methylation analysis by multiplexed reduced representation bisulfite sequencing
    DNA methylation analysis by multiplexed reduced representation...
    DNA methylation is an essential mechanism of epigenetic gene regulation with broad relevance in development and disease. Its localization on genomic DNA and general stability make this epigen...
    Speaker: Paul Datlinger
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
     
     
  • APR 04, 2016 | 8:00 AM
    Phage Antibody Selection on the Reichert SR7500DC SPR System
    Phage Antibody Selection on the Reichert SR7500DC SPR System
    DATE: April 4, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time The use of surface plasmon resonance to characterize protein:protein interactions is well established and has bee...
    Speaker: Mark Sullivan, Ph.D.
    Sponsored By: Ametek, Ametek
    9
    MAR 31, 2016 | 8:00 AM
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    Optimizing homology-directed repair (HDR) results with CRISPR-Cas9
    DATE:  March 31, 2016 TIME:   8am PT, 11am ET, 4pm GMT In this webinar, you will learn:  Basics of homology-directed repair (HDR) using CRISPR-Cas9 Selection of CRISP...
    Speaker: John Schiel, Ph.D.
    Sponsored By: Dharmacon, Dharmacon
    31 12
    MAR 17, 2016 | 9:00 AM
    Featured Speaker - The neurobiology underlying drug addiction: lessons from multimodality imaging and neuropsychological studies in humans
    Featured Speaker - The neurobiology underlying drug addiction:...
    Drug addiction is a chronically relapsing disorder characterized by compulsive drug use despite catastrophic personal consequences (e.g., loss of family, job) and even when the substance is n...
    Speaker: Rita Goldstein, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    2
    MAR 10, 2016 | 8:00 AM
    Fully Automated, One Hour Sample Preparation for Ultrafast N-Glycosylation Analysis of Antibody Therapeutics
    Fully Automated, One Hour Sample Preparation for Ultrafast N-Glycosylation...
    DATE: March 10, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time SCIEX has recently introduced an easy-to-use magnetic bead based sample preparation workflow, enabling the prepa...
    Speaker: Andras Guttman, PhD
    Sponsored By: Sciex, Sciex
    9
    FEB 04, 2016 | 6:00 AM
    Zebrafish: an upswing model in research and the need for refinement of anaesthesia
    Zebrafish: an upswing model in research and the need for refinement...
         In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
    Speaker: Ana Valentim, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
     
     
  • FEB 04, 2016 | 6:00 AM
    Steps on the route to optimising experimental design, including teaching and conducting systematic reviews
    Steps on the route to optimising experimental design, including...
    A number of elements come into the mix when trying to optimise experimental design. Among these are having clear objectives, setting up valid comparisons, knowing how to avoid bias during the...
    Speaker: Derek Fry OBE, MA, D Phil, MB BCh , Rob de Vries, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 03, 2016 | 1:30 PM
    In-house development and implementation of surgical animal models
    In-house development and implementation of surgical animal models
    Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    3
    DEC 09, 2015 | 8:00 AM
    Moisture Analysis in Pharma: Expanding Near-Infrared Spectroscopy with Karl Fischer Titration
    Moisture Analysis in Pharma: Expanding Near-Infrared Spectroscopy...
    DATE: December 9, 2015 TIME: 8am Pacific, 11am Eastern Pharmaceutical product quality, effectiveness and shelf life depends significantly on the water content in these products, which mak...
    Speaker: Joseph Head, MS , Keith Freel, PhD
    Sponsored By: Metrohm USA, Metrohm USA
    4
    NOV 24, 2015 | 6:00 AM
    Say goodbye to Gels - Real world use of LabChip micro-fluidic technology for nucleic acid and protein analysis
    Say goodbye to Gels - Real world use of LabChip micro-fluidic...
    DATE: November 24, 2015TIME: 9am EST, 2pm GMTFor many years now, gels have been a fundamental research tool in academic research for the separation and analysis of nucleic acids and pro...
    Speaker: Julius Kostan, PhD , Sandra Doran , Veronika Delcheva
    Sponsored By: Revvity
    29
    NOV 12, 2015 | 10:30 AM
    Pharmacogenetics in the Clinical Laboratory: Opportunities and Challenges
    Pharmacogenetics in the Clinical Laboratory: Opportunities and...
    Appropriate dosing of pharmaceuticals is critical to prevent sub-therapeutic efficacy or the occurrence of adverse events. However, genetic variability may significantly influence an individu...
    Speaker: Allison Chambliss, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    4
     
     
  • NOV 12, 2015 | 7:30 AM
    Keynote: Reconceptualizing Genital Herpes Diagnosis and Management
    Keynote: Reconceptualizing Genital Herpes Diagnosis and Management
    As one of the nation's most prevalent sexually transmitted infections, genital herpes represents a diagnostic and therapeutic challenge to clinicians, laboratorians and the patients they...
    Speaker: Edward Hook, III, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    2 1
    NOV 11, 2015 | 6:00 AM
    A Comprehensive Toxicology Screening Solution Targeted to Individual Needs
    A Comprehensive Toxicology Screening Solution Targeted to Individual...
    Drugs of abuse toxicology testing by immunoassays is widely used clinically, but also known to be inadequate for many clinical indications. In this presentation, the speaker will outline diff...
    Speaker: Ping Wang, PhD, DABCC, FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    3
    NOV 11, 2015 | 6:00 AM
    Clinical next-generation sequencing for precision cancer therapeutics
    Clinical next-generation sequencing for precision cancer therapeutics
    Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
    Speaker: Christina (Tina) Lockwood, PhD, DABCC, FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    2
    OCT 15, 2015 | 7:30 AM
    WEBINAR: Graduate from Shaker to Fermentor
    WEBINAR: Graduate from Shaker to Fermentor
    DATE: October 15, 2015 TIME: 7:30AM PDT, 10:30AM EDT Most cell biologists culture cells in dishes and shake flasks to produce proteins and biological molecules; however the production of ...
    Speaker: Michelet Dorceus
    Sponsored By: Eppendorf, Eppendorf
    8 1
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