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    Molecular Pathology

    Molecular Pathology: is an emerging discipline within pathology that is focused on the study and diagnosis of disease through the examination of molecules within organs, tissues or bodily fluids. Molecular pathology shares some aspects of practice with both anatomic pathology and clinical pathology, molecular biology, biochemistry, proteomics and genetics, and is sometimes considered a "crossover" discipline. It is multi-disciplinary in nature and focuses mainly on the sub-microscopic aspects of disease.

    Webinars

    • MAR 20, 2014 | 2:00 PM
      Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
      Cross-talk & Developmental Programs A Key to Translational...
      The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
      Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
      Presented at: Neuroscience Virtual Event Series 2014
      94
      MAR 20, 2014 | 1:00 PM
      The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
      The role of high throughput sequencing in the research and diagnosis...
      Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
      Speaker: Peter L Nagy, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 20, 2014 | 12:00 PM
      Axonal Protein Synthesis in Neurodevelopment and -degeneration
      Axonal Protein Synthesis in Neurodevelopment and -degeneration
      Spatially restricted protein synthesis is an important mechanism for the development and maintenance of many morphologically polarized cells including neurons. While most proteins are synthes...
      Speaker: Ulrich Hengst, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      84
      MAR 20, 2014 | 12:00 PM
      The Genetics of Alzheimer's disease
      The Genetics of Alzheimer's disease
      Alzheimers disease (AD) is a common neurodegenerative disorder characterized clinically by progress decline in memory and thinking and pathologically by the presence of senile plaques and neu...
      Speaker: Alison Goate, D.Phil
      Presented at: Neuroscience Virtual Event Series 2014
      68
      MAR 20, 2014 | 11:00 AM
      Using brain imaging and biomarkers for diagnosis and investigation of Alzheimer's disease "The Alzheimer's Disease Neuroimaging Initiat
      Using brain imaging and biomarkers for diagnosis and investigation...
      Alzheimers disease (AD) is a neurodegenerative disorder producing cognitive impairment and dementia in millions of elders. Currently no treatment is effective to slow the progression of AD. M...
      Speaker: Michael Weiner, MD
      Presented at: Neuroscience Virtual Event Series 2014
      62
      MAR 20, 2014 | 8:00 AM
      Biomarkers, Cognition and Cognitive Reserve in Alzheimers Disease
      Biomarkers, Cognition and Cognitive Reserve in Alzheimers Disease
      Late onset dementia is usually a multi-factorial disease wherein cumulative pathological brain insults (of more than one pathology) results in progressive cognitive decline which ultimately l...
      Speaker: Prashanthi Vemuri, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      104
      MAR 19, 2014 | 1:00 PM
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
      Speaker: Radosveta Koldamova, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      56
      MAR 19, 2014 | 10:00 AM
      NMDA receptor regulation in health and disease
      NMDA receptor regulation in health and disease
      Neuron-glial interactions are increasingly recognized as being key for physiological and pathological processes in the central nervous system. Microglia have been found to play a causal role...
      Speaker: Michael Salter, MD, PhD, FRSC
      Presented at: Neuroscience Virtual Event Series 2014
      54
      MAR 19, 2014 | 7:00 AM
      A Unique B Cell Derived Signature of Multiple Sclerosis and its Biologic Implications
      A Unique B Cell Derived Signature of Multiple Sclerosis and its...
      Multiple Sclerosis (MS) is an autoimmune disease that leads to widespread pathology within the central nervous system (CNS) and is the most common cause of neurologic disability among young a...
      Speaker: Benjamin Greenberg, MD
      Presented at: Neuroscience Virtual Event Series 2014
      34
      MAR 19, 2014 | 7:00 AM
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
      Speaker: Ahmad Salehi, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      15
      MAR 19, 2014 | 6:00 AM
      The Novel Neurotechnology: implications for science, medicine and society
      The Novel Neurotechnology: implications for science, medicine...
      In physical systems built with many components, emergent properties, such as magnetism, are often generated from the interactions among these particles. These emergent properties are often in...
      Speaker: Rafael Yuste, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      138
      FEB 19, 2014 | 10:00 AM
      Next-generation sequencing applications in advanced cancer samples: Experience with Ion AmpliSeq custom panels
      Next-generation sequencing applications in advanced cancer samples:...
      Making precision cancer care a future reality requires novel approachesto finding treatment targets in cancers. Single-gene assays currently performed in clinical research laboratories are in...
      Speaker: Christopher Corless, MD, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Winter
      122
      NOV 20, 2013 | 10:00 AM
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
      2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
      Speaker: Nicole Littmann
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      50
      OCT 17, 2013 | 9:00 AM
      C.E. CREDITS
      Subtyping Circulating Tumor Cells in Breast Cancer for Personalized Therapeutics
      Subtyping Circulating Tumor Cells in Breast Cancer for Personalized...
      Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
      Speaker: Lori M. Millner, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      86
      OCT 16, 2013 | 2:00 PM
      C.E. CREDITS
      Novel therapies for ALK mutated cancers
      Novel therapies for ALK mutated cancers
      Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
      Speaker: Roberto Chiarle, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      32
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Molecular Diagnostics in Detection, Diagnosis, and Prognosis of Cancer
      Molecular Diagnostics in Detection, Diagnosis, and Prognosis of...
      Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      129
      OCT 16, 2013 | 12:00 PM
      C.E. CREDITS
      New therapeutic strategies and new modes of drug resistance: From the bench to bedside and back again with the oncogene eIF4E
      New therapeutic strategies and new modes of drug resistance: From...
      The eukaryotic translation initiation factor eIF4E is a potent oncogene estimated to be elevated in about 30% of human cancers including cancers of the breast, prostate, lung, colon as well a...
      Speaker: Katherine LB Borden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      60
      OCT 16, 2013 | 12:00 PM
      Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based Proteomics and Digital Pathology
      Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based...
      The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
      Speaker: William M. Gallagher, PhD.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      98
      OCT 16, 2013 | 9:00 AM
      C.E. CREDITS
      Keynote: Breast Cancer Genomics and Genetics
      Keynote: Breast Cancer Genomics and Genetics
      It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
      Speaker: Charles M. Perou, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      132
      AUG 22, 2013 | 12:00 PM
      C.E. CREDITS
      Exome Sequencing as a Diagnostic Tool
      Exome Sequencing as a Diagnostic Tool
      It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
      Speaker: Pinar Bayrak-Toydemir, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      66
      AUG 22, 2013 | 10:00 AM
      C.E. CREDITS
      Clinical Interpretation of Sequence Variants
      Clinical Interpretation of Sequence Variants
      The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
      Speaker: Elaine Lyon, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      72
      AUG 21, 2013 | 1:00 PM
      Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
      Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
      Cervical cancer screening has evolved significantly since the PAP smear was introduced in 1949. In particular, the association with human papillomavirus (HPV) infection and the mechanism of H...
      Speaker: Bruce K Patterson, MD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      59 1
      AUG 21, 2013 | 10:00 AM
      C.E. CREDITS
      Genomic Approaches to Discover Biomarkers of Drug Response in Cancer
      Genomic Approaches to Discover Biomarkers of Drug Response in...
      Massively parallel sequencing technology has proven to enable the identification of driver genetic alterations in patients' tumors that may be suppressed by targeted therapies. Through retros...
      Speaker: Michael F Berger, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      117
      AUG 21, 2013 | 8:00 AM
      C.E. CREDITS
      Implementation of genome sequencing in a clinical diagnostic laboratory
      Implementation of genome sequencing in a clinical diagnostic laboratory
      With the technical costs of genome sequencing continuously dropping, it is now feasible to offer this assay in a clinical context. Empirical evidence suggests that genome and exome sequencing...
      Speaker: Matthew Lebo, PhD, FACMG
      Presented at: Genetics and Genomics Virtual Event Series 2013
      79
    MAR 20, 2014 | 2:00 PM
    Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
    Cross-talk & Developmental Programs A Key to Translational...
    The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
    Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
    Presented at: Neuroscience Virtual Event Series 2014
    94
    MAR 20, 2014 | 1:00 PM
    The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
    The role of high throughput sequencing in the research and diagnosis...
    Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
    Speaker: Peter L Nagy, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    MAR 20, 2014 | 12:00 PM
    Axonal Protein Synthesis in Neurodevelopment and -degeneration
    Axonal Protein Synthesis in Neurodevelopment and -degeneration
    Spatially restricted protein synthesis is an important mechanism for the development and maintenance of many morphologically polarized cells including neurons. While most proteins are synthes...
    Speaker: Ulrich Hengst, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    84
    MAR 20, 2014 | 12:00 PM
    The Genetics of Alzheimer's disease
    The Genetics of Alzheimer's disease
    Alzheimers disease (AD) is a common neurodegenerative disorder characterized clinically by progress decline in memory and thinking and pathologically by the presence of senile plaques and neu...
    Speaker: Alison Goate, D.Phil
    Presented at: Neuroscience Virtual Event Series 2014
    68
    MAR 20, 2014 | 11:00 AM
    Using brain imaging and biomarkers for diagnosis and investigation of Alzheimer's disease "The Alzheimer's Disease Neuroimaging Initiat
    Using brain imaging and biomarkers for diagnosis and investigation...
    Alzheimers disease (AD) is a neurodegenerative disorder producing cognitive impairment and dementia in millions of elders. Currently no treatment is effective to slow the progression of AD. M...
    Speaker: Michael Weiner, MD
    Presented at: Neuroscience Virtual Event Series 2014
    62
     
     
  • MAR 20, 2014 | 8:00 AM
    Biomarkers, Cognition and Cognitive Reserve in Alzheimers Disease
    Biomarkers, Cognition and Cognitive Reserve in Alzheimers Disease
    Late onset dementia is usually a multi-factorial disease wherein cumulative pathological brain insults (of more than one pathology) results in progressive cognitive decline which ultimately l...
    Speaker: Prashanthi Vemuri, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    104
    MAR 19, 2014 | 1:00 PM
    ABCA1 and APOE: Intertwined roles in Alzheimers disease
    ABCA1 and APOE: Intertwined roles in Alzheimers disease
    ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
    Speaker: Radosveta Koldamova, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    56
    MAR 19, 2014 | 10:00 AM
    NMDA receptor regulation in health and disease
    NMDA receptor regulation in health and disease
    Neuron-glial interactions are increasingly recognized as being key for physiological and pathological processes in the central nervous system. Microglia have been found to play a causal role...
    Speaker: Michael Salter, MD, PhD, FRSC
    Presented at: Neuroscience Virtual Event Series 2014
    54
    MAR 19, 2014 | 7:00 AM
    A Unique B Cell Derived Signature of Multiple Sclerosis and its Biologic Implications
    A Unique B Cell Derived Signature of Multiple Sclerosis and its...
    Multiple Sclerosis (MS) is an autoimmune disease that leads to widespread pathology within the central nervous system (CNS) and is the most common cause of neurologic disability among young a...
    Speaker: Benjamin Greenberg, MD
    Presented at: Neuroscience Virtual Event Series 2014
    34
    MAR 19, 2014 | 7:00 AM
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
    Speaker: Ahmad Salehi, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    15
     
     
  • MAR 19, 2014 | 6:00 AM
    The Novel Neurotechnology: implications for science, medicine and society
    The Novel Neurotechnology: implications for science, medicine...
    In physical systems built with many components, emergent properties, such as magnetism, are often generated from the interactions among these particles. These emergent properties are often in...
    Speaker: Rafael Yuste, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    138
    FEB 19, 2014 | 10:00 AM
    Next-generation sequencing applications in advanced cancer samples: Experience with Ion AmpliSeq custom panels
    Next-generation sequencing applications in advanced cancer samples:...
    Making precision cancer care a future reality requires novel approachesto finding treatment targets in cancers. Single-gene assays currently performed in clinical research laboratories are in...
    Speaker: Christopher Corless, MD, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Winter
    122
    NOV 20, 2013 | 10:00 AM
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
    2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
    Speaker: Nicole Littmann
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    50
    OCT 17, 2013 | 9:00 AM
    C.E. CREDITS
    Subtyping Circulating Tumor Cells in Breast Cancer for Personalized Therapeutics
    Subtyping Circulating Tumor Cells in Breast Cancer for Personalized...
    Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
    Speaker: Lori M. Millner, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    86
    OCT 16, 2013 | 2:00 PM
    C.E. CREDITS
    Novel therapies for ALK mutated cancers
    Novel therapies for ALK mutated cancers
    Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
    Speaker: Roberto Chiarle, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    32
     
     
  • OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Molecular Diagnostics in Detection, Diagnosis, and Prognosis of Cancer
    Molecular Diagnostics in Detection, Diagnosis, and Prognosis of...
    Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    129
    OCT 16, 2013 | 12:00 PM
    C.E. CREDITS
    New therapeutic strategies and new modes of drug resistance: From the bench to bedside and back again with the oncogene eIF4E
    New therapeutic strategies and new modes of drug resistance: From...
    The eukaryotic translation initiation factor eIF4E is a potent oncogene estimated to be elevated in about 30% of human cancers including cancers of the breast, prostate, lung, colon as well a...
    Speaker: Katherine LB Borden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    60
    OCT 16, 2013 | 12:00 PM
    Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based Proteomics and Digital Pathology
    Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based...
    The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
    Speaker: William M. Gallagher, PhD.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    98
    OCT 16, 2013 | 9:00 AM
    C.E. CREDITS
    Keynote: Breast Cancer Genomics and Genetics
    Keynote: Breast Cancer Genomics and Genetics
    It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
    Speaker: Charles M. Perou, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    132
    AUG 22, 2013 | 12:00 PM
    C.E. CREDITS
    Exome Sequencing as a Diagnostic Tool
    Exome Sequencing as a Diagnostic Tool
    It is widely accepted that approximately 85% of known disease-causing DNA variants affect the exons and splice junctions, which is about 1% of the whole genome. As a result, Clinical Exome Se...
    Speaker: Pinar Bayrak-Toydemir, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    66
     
     
  • AUG 22, 2013 | 10:00 AM
    C.E. CREDITS
    Clinical Interpretation of Sequence Variants
    Clinical Interpretation of Sequence Variants
    The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in ge...
    Speaker: Elaine Lyon, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    72
    AUG 21, 2013 | 1:00 PM
    Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
    Bioinformatics and Quantitative Genomics in Cervical Cancer Screening
    Cervical cancer screening has evolved significantly since the PAP smear was introduced in 1949. In particular, the association with human papillomavirus (HPV) infection and the mechanism of H...
    Speaker: Bruce K Patterson, MD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    59 1
    AUG 21, 2013 | 10:00 AM
    C.E. CREDITS
    Genomic Approaches to Discover Biomarkers of Drug Response in Cancer
    Genomic Approaches to Discover Biomarkers of Drug Response in...
    Massively parallel sequencing technology has proven to enable the identification of driver genetic alterations in patients' tumors that may be suppressed by targeted therapies. Through retros...
    Speaker: Michael F Berger, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    117
    AUG 21, 2013 | 8:00 AM
    C.E. CREDITS
    Implementation of genome sequencing in a clinical diagnostic laboratory
    Implementation of genome sequencing in a clinical diagnostic laboratory
    With the technical costs of genome sequencing continuously dropping, it is now feasible to offer this assay in a clinical context. Empirical evidence suggests that genome and exome sequencing...
    Speaker: Matthew Lebo, PhD, FACMG
    Presented at: Genetics and Genomics Virtual Event Series 2013
    79
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