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    Neurodegeneration

    Neurodegeneration: The continuous loss of neuronal structure or function of neurons, including death of neurons. This loss can ultimately lead to cognitive disability and dementia. Usally, neurodegeneration is linked to a disease such as Parkinson's disease, Alzheimer's disease, and Huntington's disease.

    Webinars

    • DEC 07, 2023 | 8:00 AM
      Translating COSMIC's gold standard data into actionable insights
      Translating COSMIC's gold standard data into actionable insights
      As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...
      Speaker: Leonie Hodges , Alex Holmes, Ph.D. , Jennifer Wilding, Ph.D.
      Sponsored By: QIAGEN
      15
      OCT 25, 2023 | 10:00 AM
      Introduction of a New Thiol-based Fluorescent Indicator to Assess Cellular Health Using Induced Pluripotent Stem Cell Derived Neurons
      Introduction of a New Thiol-based Fluorescent Indicator to Assess...
      Oxidative stress, a critical factor affecting cell health, has gained prominence in assessing various medical conditions. Given this importance, researchers need a wide range of tools to tho...
      Speaker: Daniel Sem, Ph.D., MBA, JD , Roxanne Alvarez, Ph.D.
      Sponsored By: BrainXell, Vivid Microscopy
      10
      OCT 24, 2023 | 8:00 AM
      Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
      Scaling Up Organoid Research: A New Approach with Assay-Ready...
      Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
      Speaker: Angeline Lim , Andy Bashford
      Sponsored By: Molecular Devices
      9
      OCT 24, 2023 | 10:00 AM
      Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
      Scaling Up Organoid Research: A New Approach with Assay-Ready...
      Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
      Speaker: Angeline Lim , Andy Bashford
      Sponsored By: Molecular Devices
      12
      AUG 23, 2023 | 10:00 AM
      Emerging role of neuroinflammation in C9orf72-ALS
      Emerging role of neuroinflammation in C9orf72-ALS
      C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
      Speaker: Deepti Lall, PhD
      Sponsored By: Miltenyi Biotec
      16
      AUG 01, 2023 | 10:00 PM
      Unraveling the Potential of Neural Stem Cells: Antibodies as Key Tools
      Unraveling the Potential of Neural Stem Cells: Antibodies as Key...
      Stem cells have the capability to develop into any specialized cell type, which makes them a valuable resource in research and regenerative medicine. Differentiated stem cell models provide...
      Speaker: Jamuna KS
      Sponsored By: Thermo Fisher Scientific
      33
      JUL 26, 2023 | 2:30 PM
      Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
      Serine-129 phosphorylation of α-synuclein is an activity-dependent...
      Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
      Speaker: Dr. Leonardo Parra-Rivas
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      MAR 28, 2023 | 3:30 AM
      Biofluid-based biomarkers for neurological disease
      Biofluid-based biomarkers for neurological disease
      Date: March 28, 2023 Time: 3:30am (PDT), 6:30am (EDT), 12:30pm (CEST) Biofluid-based neurological biomarkers have shown promise in helping to improve diagnostic accuracy, predict disease pro...
      Speaker: Steffen Halbgebauer, PhD , Dr. Hayrettin Tumani , Yoav Noam, PhD
      Sponsored By: Bio-Techne
      20
      MAR 08, 2023 | 6:00 AM
      Understanding the Role of Alzheimer's Disease Pathologies in Spatial Memory Dysfunction
      Understanding the Role of Alzheimer's Disease Pathologies in Spatial...
      Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
      Speaker: Abid Hussaini, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      2
      MAR 08, 2023 | 6:00 AM
      Novel Tools for Drug Discovery in Neurodegenerative Diseases
      Novel Tools for Drug Discovery in Neurodegenerative Diseases
      Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Both diseases are characterized by abnormal aggregates in the brain, which incl...
      Speaker: Jacob McPhail, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      3
      MAR 08, 2023 | 6:00 AM
      Selective Neuronal Vulnerability in Neurodegeneration
      Selective Neuronal Vulnerability in Neurodegeneration
      Selective vulnerability of brain regions and specific neural populations in neurodegeneration remains little understood. We hypothesize that pre-existing physiological differences in neurons...
      Speaker: Marija Cvetanovic, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      2
      OCT 04, 2022 | 7:00 AM
      Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
      Tools & Strategies for Implementing iPSC-based Cell Models for...
      Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
      Speaker: Benjamin Schmid , Peter Reinhardt
      Sponsored By: Bioneer A/S
      13
      JUL 19, 2022 | 8:00 AM
      Getting started in Cryo-EM
      Getting started in Cryo-EM
      Date: July 19, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Cryo-EM is rapidly becoming the method of choice for structural biologists and biochemists around the world, helping thes...
      Speaker: Melissa Chambers , Natalia de Val
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      9
      MAY 04, 2022 | 5:30 AM
      Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
      Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
      Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
      Speaker: Tracy Fischer, PhD
      Presented at: Coronavirus Series
      2
      AUG 25, 2021 | 1:30 PM
      Spatial Transcriptomics of Alzheimer's Disease Mouse Models with and Without Trem2R47H Mutation.
      Spatial Transcriptomics of Alzheimer's Disease Mouse Models with...
      In this preliminary experiment, we used spatial transcriptomics to assess the gene expression profiles of microglia or astrocytes in relation to their distance from plaques. We compared 18-m...
      Speaker: Frances Edwards, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: NanoString Technologies
      1
      AUG 25, 2021 | 10:30 AM
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
      Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
      Speaker: Jason D. Hinman, PhD, MD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: Luminex
      2
      APR 22, 2021 | 5:00 PM
      Researchers share their Spatial Discoveries in Neurology Research
      Researchers share their Spatial Discoveries in Neurology Research
      Date: April 22, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) System transcriptomics of the schizophrenia brain - Phillip Khaitovich Schizophrenia tops the psychiatric disorder l...
      Speaker: Philipp Khaitovich , Joan Liu
      Sponsored By: NanoString Technologies, Illumina
      5
      APR 21, 2021 | 5:00 PM
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
      Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
      Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
      Sponsored By: NanoString Technologies, Illumina
      5
      NOV 18, 2020 | 8:00 AM
      Whole-organ mapping using AI and light sheet microscopy
      Whole-organ mapping using AI and light sheet microscopy
      DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
      Speaker: Ali Ertürk
      Sponsored By: Miltenyi Biotec
      14
      JUL 29, 2020 | 12:00 PM
      Linking Cancer Metabolism to Neurodegeneration
      Linking Cancer Metabolism to Neurodegeneration
      The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
      Speaker: Navdeep S. Chandel PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      3
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      MAR 11, 2020 | 10:30 AM
      Innate immunity in chronic neurodegeneration
      Innate immunity in chronic neurodegeneration
      The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
      Speaker: Michael Heneka, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      JAN 01, 2020 | 6:00 AM
      Investigating the roles of the  Hsp90 co-chaperone, STI1, in neuronal resilience during aging
      Investigating the roles of the Hsp90 co-chaperone, STI1, in neuronal...
      Chaperone networks are dysregulated with aging, but whether compromised Hsp70/Hsp90 chaperone function disturbs neuronal resilience is unknown. Stress‐inducible phosphoprotein 1 (STI1; STIP1...
      Speaker: Rachel Lackie, HBSc.
      Presented at: Neuroscience Virtual Event Series 2020
      1
    DEC 07, 2023 | 8:00 AM
    Translating COSMIC's gold standard data into actionable insights
    Translating COSMIC's gold standard data into actionable insights
    As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...
    Speaker: Leonie Hodges , Alex Holmes, Ph.D. , Jennifer Wilding, Ph.D.
    Sponsored By: QIAGEN
    15
    OCT 25, 2023 | 10:00 AM
    Introduction of a New Thiol-based Fluorescent Indicator to Assess Cellular Health Using Induced Pluripotent Stem Cell Derived Neurons
    Introduction of a New Thiol-based Fluorescent Indicator to Assess...
    Oxidative stress, a critical factor affecting cell health, has gained prominence in assessing various medical conditions. Given this importance, researchers need a wide range of tools to tho...
    Speaker: Daniel Sem, Ph.D., MBA, JD , Roxanne Alvarez, Ph.D.
    Sponsored By: BrainXell, Vivid Microscopy
    10
    OCT 24, 2023 | 8:00 AM
    Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
    Scaling Up Organoid Research: A New Approach with Assay-Ready...
    Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
    Speaker: Angeline Lim , Andy Bashford
    Sponsored By: Molecular Devices
    9
    OCT 24, 2023 | 10:00 AM
    Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
    Scaling Up Organoid Research: A New Approach with Assay-Ready...
    Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
    Speaker: Angeline Lim , Andy Bashford
    Sponsored By: Molecular Devices
    12
    AUG 23, 2023 | 10:00 AM
    Emerging role of neuroinflammation in C9orf72-ALS
    Emerging role of neuroinflammation in C9orf72-ALS
    C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
    Speaker: Deepti Lall, PhD
    Sponsored By: Miltenyi Biotec
    16
     
     
  • AUG 01, 2023 | 10:00 PM
    Unraveling the Potential of Neural Stem Cells: Antibodies as Key Tools
    Unraveling the Potential of Neural Stem Cells: Antibodies as Key...
    Stem cells have the capability to develop into any specialized cell type, which makes them a valuable resource in research and regenerative medicine. Differentiated stem cell models provide...
    Speaker: Jamuna KS
    Sponsored By: Thermo Fisher Scientific
    33
    JUL 26, 2023 | 2:30 PM
    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
    Serine-129 phosphorylation of α-synuclein is an activity-dependent...
    Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
    Speaker: Dr. Leonardo Parra-Rivas
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    MAR 28, 2023 | 3:30 AM
    Biofluid-based biomarkers for neurological disease
    Biofluid-based biomarkers for neurological disease
    Date: March 28, 2023 Time: 3:30am (PDT), 6:30am (EDT), 12:30pm (CEST) Biofluid-based neurological biomarkers have shown promise in helping to improve diagnostic accuracy, predict disease pro...
    Speaker: Steffen Halbgebauer, PhD , Dr. Hayrettin Tumani , Yoav Noam, PhD
    Sponsored By: Bio-Techne
    20
    MAR 08, 2023 | 6:00 AM
    Understanding the Role of Alzheimer's Disease Pathologies in Spatial Memory Dysfunction
    Understanding the Role of Alzheimer's Disease Pathologies in Spatial...
    Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
    Speaker: Abid Hussaini, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    2
    MAR 08, 2023 | 6:00 AM
    Novel Tools for Drug Discovery in Neurodegenerative Diseases
    Novel Tools for Drug Discovery in Neurodegenerative Diseases
    Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Both diseases are characterized by abnormal aggregates in the brain, which incl...
    Speaker: Jacob McPhail, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    3
     
     
  • MAR 08, 2023 | 6:00 AM
    Selective Neuronal Vulnerability in Neurodegeneration
    Selective Neuronal Vulnerability in Neurodegeneration
    Selective vulnerability of brain regions and specific neural populations in neurodegeneration remains little understood. We hypothesize that pre-existing physiological differences in neurons...
    Speaker: Marija Cvetanovic, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    2
    OCT 04, 2022 | 7:00 AM
    Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
    Tools & Strategies for Implementing iPSC-based Cell Models for...
    Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
    Speaker: Benjamin Schmid , Peter Reinhardt
    Sponsored By: Bioneer A/S
    13
    JUL 19, 2022 | 8:00 AM
    Getting started in Cryo-EM
    Getting started in Cryo-EM
    Date: July 19, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Cryo-EM is rapidly becoming the method of choice for structural biologists and biochemists around the world, helping thes...
    Speaker: Melissa Chambers , Natalia de Val
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    9
    MAY 04, 2022 | 5:30 AM
    Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
    Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
    Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
    Speaker: Tracy Fischer, PhD
    Presented at: Coronavirus Series
    2
    AUG 25, 2021 | 1:30 PM
    Spatial Transcriptomics of Alzheimer's Disease Mouse Models with and Without Trem2R47H Mutation.
    Spatial Transcriptomics of Alzheimer's Disease Mouse Models with...
    In this preliminary experiment, we used spatial transcriptomics to assess the gene expression profiles of microglia or astrocytes in relation to their distance from plaques. We compared 18-m...
    Speaker: Frances Edwards, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: NanoString Technologies
    1
     
     
  • AUG 25, 2021 | 10:30 AM
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
    Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
    Speaker: Jason D. Hinman, PhD, MD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: Luminex
    2
    APR 22, 2021 | 5:00 PM
    Researchers share their Spatial Discoveries in Neurology Research
    Researchers share their Spatial Discoveries in Neurology Research
    Date: April 22, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) System transcriptomics of the schizophrenia brain - Phillip Khaitovich Schizophrenia tops the psychiatric disorder l...
    Speaker: Philipp Khaitovich , Joan Liu
    Sponsored By: NanoString Technologies, Illumina
    5
    APR 21, 2021 | 5:00 PM
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
    Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
    Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
    Sponsored By: NanoString Technologies, Illumina
    5
    NOV 18, 2020 | 8:00 AM
    Whole-organ mapping using AI and light sheet microscopy
    Whole-organ mapping using AI and light sheet microscopy
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    Speaker: Ali Ertürk
    Sponsored By: Miltenyi Biotec
    14
    JUL 29, 2020 | 12:00 PM
    Linking Cancer Metabolism to Neurodegeneration
    Linking Cancer Metabolism to Neurodegeneration
    The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
    Speaker: Navdeep S. Chandel PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    3
     
     
  • JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    MAR 11, 2020 | 10:30 AM
    Innate immunity in chronic neurodegeneration
    Innate immunity in chronic neurodegeneration
    The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
    Speaker: Michael Heneka, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    JAN 01, 2020 | 6:00 AM
    Investigating the roles of the  Hsp90 co-chaperone, STI1, in neuronal resilience during aging
    Investigating the roles of the Hsp90 co-chaperone, STI1, in neuronal...
    Chaperone networks are dysregulated with aging, but whether compromised Hsp70/Hsp90 chaperone function disturbs neuronal resilience is unknown. Stress‐inducible phosphoprotein 1 (STI1; STIP1...
    Speaker: Rachel Lackie, HBSc.
    Presented at: Neuroscience Virtual Event Series 2020
    1
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