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    Translational Research

    Translational Research: involves the application of knowledge gained through basic research to studies that could support the development of new products. For example, translational research in the field of medicine may involve using knowledge of the biology of a disease to identify and evaluate chemical compounds in disease models, with a view to selecting potential candidate drugs to advance into clinical trials.

    Webinars

    • SEP 09, 2020 | 12:00 AM
      Fc gamma receptor activation during viral infections: a double-edged sword
      Fc gamma receptor activation during viral infections: a double-edged...
      Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
      Speaker: Raymond A. Alvarez, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Lung immune cells as drivers of influenza outcomes
      Lung immune cells as drivers of influenza outcomes
      Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
      Speaker: Juliet Morrison, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Nanoparticle-based next-generation influenza vaccines
      Nanoparticle-based next-generation influenza vaccines
      Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
      Speaker: Masaru Kanekiyo, DVM, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 01, 2020 | 8:00 AM
      Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
      Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
      DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
      Speaker: Justin Balko
      Sponsored By: Thermo Fisher Scientific
      20 1
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      AUG 11, 2020 | 10:00 AM
      Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
      Better resolution for CE-SDS analysis of new biopharmaceutical...
      DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
      Speaker: Andras Guttman, PhD
      Sponsored By: SCIEX
      9 4
      AUG 07, 2020 | 12:00 PM
      Part IV: How to be a sane clinician scientist - a timeline
      Part IV: How to be a sane clinician scientist - a timeline
      This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
      Speaker: Lois Smith, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 07, 2020 | 12:00 PM
      Part I: Dual Degrees and Dual Careers -- The Interface between Neurology and Neuroscience
      Part I: Dual Degrees and Dual Careers -- The Interface between...
      During this seminar I will present details of my path from Beckman Scholar to MD-PhD, advanced training as a neurologist, then a neurointensivist, and the interleaving of additional research...
      Speaker: Terrance T. Kummer, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 07, 2020 | 9:00 AM
      Part I: The Team, the Generalist, and Seeing Through Blind Spots
      Part I: The Team, the Generalist, and Seeing Through Blind Spots
      I will tell brief stories of experiences that have shaped my career, generalize the lessons learned, and translate them to three actionable items: (1) be careful with your pronouns, (2) embr...
      Speaker: Jeffrey S. Moore, PhD
      Presented at: 2020 Beckman Symposium
      2
      AUG 06, 2020 | 10:00 AM
      Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      Part VII: From biochemical nanosensors to imaging to informatics...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 10:00 AM
      Part IV: SPARC - A method to genetically manipulate precise proportions of cells
      Part IV: SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      2
      AUG 06, 2020 | 12:00 AM
      SPARC - A method to genetically manipulate precise proportions of cells
      SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      From biochemical nanosensors to imaging to informatics to COVID-19...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 29, 2020 | 5:00 PM
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
      Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 2:00 PM
      Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
      Route of 41BB/41BBL costimulation determines effector function...
      B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
      Speaker: Christopher DeRenzo, MD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 1:00 PM
      Using quantitative imaging microscopy to explore and target the molecular origins of cancer
      Using quantitative imaging microscopy to explore and target the...
      The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
      Speaker: Kirk McManus, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 07, 2020 | 10:30 AM
      Identification of human immune cell subtypes most vulnerable to IL-1β-induced inflammatory signaling using mass cytometry
      Identification of human immune cell subtypes most vulnerable to...
      Cytokine storm is suspected of producing the overzealous immune response driving the severe cardiopulmonary complications that fuel high morbidity and mortality rates in certain COVID-19 inf...
      Speaker: Hema Kothari, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 9:30 AM
      Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
      Evaluating tumor-immune cell interactions in human lung cancer...
      ...
      Speaker: Kurt Schalper, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 07, 2020 | 8:00 AM
      Development of an extraction-free, saliva-based workflow for SARS-CoV-2 detection with the Biomarkâ„¢ HD platform
      Development of an extraction-free, saliva-based workflow for SARS-CoV-2...
      The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
      Speaker: David King, PhD , Richard Head, MS
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 02, 2020 | 12:45 PM
      Cancer genomics research on tumor clonality and liquid biopsy
      Cancer genomics research on tumor clonality and liquid biopsy
      Most bladder cancer (BC) cases are non-muscle-invasive BC (NIBMC), which is rarely lethal. However, nearly one-fifth of NMIBC cases progress to muscle-invasive BC (MIBC), which shows a 5-yea...
      Speaker: Yosuke Hirotsu, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 30, 2020 | 8:00 AM
      Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex Technology
      Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex...
      DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
      Speaker: Chifei Sun
      Sponsored By: Leica Biosystems
      19
      JUN 17, 2020 | 11:00 AM
      Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's ExD Cell
      Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's...
      The ExD Option, available for both new and existing Agilent instruments, offers superior electron fragmentation in combination with collision induced dissociation (CID) compared to other exi...
      Speaker: Christian Klein, PhD , Joe Beckman, PhD
      Presented at: Agilent's Virtual Mass Spectacular!
      1
      JUN 17, 2020 | 10:00 AM
      Pharma/BioPharma Presentations and Q&A
      Pharma/BioPharma Presentations and Q&A
      ...
      Speaker: Sushmita (Mimi) Roy, PhD , Rahul Raman, PhD
      Presented at: Agilent's Virtual Mass Spectacular!
      2
    SEP 09, 2020 | 12:00 AM
    Fc gamma receptor activation during viral infections: a double-edged sword
    Fc gamma receptor activation during viral infections: a double-edged...
    Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
    Speaker: Raymond A. Alvarez, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    Lung immune cells as drivers of influenza outcomes
    Lung immune cells as drivers of influenza outcomes
    Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
    Speaker: Juliet Morrison, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Nanoparticle-based next-generation influenza vaccines
    Nanoparticle-based next-generation influenza vaccines
    Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
    Speaker: Masaru Kanekiyo, DVM, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 01, 2020 | 8:00 AM
    Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
    Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
    DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
    Speaker: Justin Balko
    Sponsored By: Thermo Fisher Scientific
    20 1
    AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
     
     
  • AUG 11, 2020 | 10:00 AM
    Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
    Better resolution for CE-SDS analysis of new biopharmaceutical...
    DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
    Speaker: Andras Guttman, PhD
    Sponsored By: SCIEX
    9 4
    AUG 07, 2020 | 12:00 PM
    Part IV: How to be a sane clinician scientist - a timeline
    Part IV: How to be a sane clinician scientist - a timeline
    This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
    Speaker: Lois Smith, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 07, 2020 | 12:00 PM
    Part I: Dual Degrees and Dual Careers -- The Interface between Neurology and Neuroscience
    Part I: Dual Degrees and Dual Careers -- The Interface between...
    During this seminar I will present details of my path from Beckman Scholar to MD-PhD, advanced training as a neurologist, then a neurointensivist, and the interleaving of additional research...
    Speaker: Terrance T. Kummer, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 07, 2020 | 9:00 AM
    Part I: The Team, the Generalist, and Seeing Through Blind Spots
    Part I: The Team, the Generalist, and Seeing Through Blind Spots
    I will tell brief stories of experiences that have shaped my career, generalize the lessons learned, and translate them to three actionable items: (1) be careful with your pronouns, (2) embr...
    Speaker: Jeffrey S. Moore, PhD
    Presented at: 2020 Beckman Symposium
    2
    AUG 06, 2020 | 10:00 AM
    Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    Part VII: From biochemical nanosensors to imaging to informatics...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
     
     
  • AUG 06, 2020 | 10:00 AM
    Part IV: SPARC - A method to genetically manipulate precise proportions of cells
    Part IV: SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    2
    AUG 06, 2020 | 12:00 AM
    SPARC - A method to genetically manipulate precise proportions of cells
    SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    From biochemical nanosensors to imaging to informatics to COVID-19...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 29, 2020 | 5:00 PM
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
    Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 2:00 PM
    Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
    Route of 41BB/41BBL costimulation determines effector function...
    B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
    Speaker: Christopher DeRenzo, MD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
     
     
  • JUL 29, 2020 | 1:00 PM
    Using quantitative imaging microscopy to explore and target the molecular origins of cancer
    Using quantitative imaging microscopy to explore and target the...
    The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
    Speaker: Kirk McManus, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 07, 2020 | 10:30 AM
    Identification of human immune cell subtypes most vulnerable to IL-1β-induced inflammatory signaling using mass cytometry
    Identification of human immune cell subtypes most vulnerable to...
    Cytokine storm is suspected of producing the overzealous immune response driving the severe cardiopulmonary complications that fuel high morbidity and mortality rates in certain COVID-19 inf...
    Speaker: Hema Kothari, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 9:30 AM
    Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
    Evaluating tumor-immune cell interactions in human lung cancer...
    ...
    Speaker: Kurt Schalper, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUL 07, 2020 | 8:00 AM
    Development of an extraction-free, saliva-based workflow for SARS-CoV-2 detection with the Biomarkâ„¢ HD platform
    Development of an extraction-free, saliva-based workflow for SARS-CoV-2...
    The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
    Speaker: David King, PhD , Richard Head, MS
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUL 02, 2020 | 12:45 PM
    Cancer genomics research on tumor clonality and liquid biopsy
    Cancer genomics research on tumor clonality and liquid biopsy
    Most bladder cancer (BC) cases are non-muscle-invasive BC (NIBMC), which is rarely lethal. However, nearly one-fifth of NMIBC cases progress to muscle-invasive BC (MIBC), which shows a 5-yea...
    Speaker: Yosuke Hirotsu, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
     
     
  • JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    JUN 30, 2020 | 8:00 AM
    Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex Technology
    Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex...
    DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
    Speaker: Chifei Sun
    Sponsored By: Leica Biosystems
    19
    JUN 17, 2020 | 11:00 AM
    Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's ExD Cell
    Breaking the Bonds, Not the Bank: New Possibilities with e-MSion's...
    The ExD Option, available for both new and existing Agilent instruments, offers superior electron fragmentation in combination with collision induced dissociation (CID) compared to other exi...
    Speaker: Christian Klein, PhD , Joe Beckman, PhD
    Presented at: Agilent's Virtual Mass Spectacular!
    1
    JUN 17, 2020 | 10:00 AM
    Pharma/BioPharma Presentations and Q&A
    Pharma/BioPharma Presentations and Q&A
    ...
    Speaker: Sushmita (Mimi) Roy, PhD , Rahul Raman, PhD
    Presented at: Agilent's Virtual Mass Spectacular!
    2
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