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    Translational Research

    Translational Research: involves the application of knowledge gained through basic research to studies that could support the development of new products. For example, translational research in the field of medicine may involve using knowledge of the biology of a disease to identify and evaluate chemical compounds in disease models, with a view to selecting potential candidate drugs to advance into clinical trials.

    Webinars

    • SEP 16, 2020 | 10:00 AM
      New Crossroad: The Intersection of COVID-19 and Sepsis
      New Crossroad: The Intersection of COVID-19 and Sepsis
      Date: September 16, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Learning Objectives Compare and contrast viral sepsis with focus on sepsis symptoms caused by SARS-CoV- The role of rapid testing f...
      Speaker: Donna Wolk, MHA, PhD, D(ABMM)
      Sponsored By: BD
      16 1
      SEP 11, 2020 | 8:00 AM
      Implementing a World-Class Clinical Pharmacogenomics Service
      Implementing a World-Class Clinical Pharmacogenomics Service
      DATE: September 11, 2020 TIME: 08:00am PT, 11:00pm ET This is the third topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. Pharmacog...
      Speaker: Dr. Hyun Kim
      Sponsored By: Thermo Fisher Scientific/Gibco
      8 2
      SEP 10, 2020 | 3:00 PM
      Plant Microbiome: Harnessing Core Microbiome for Sustainable Agricultures
      Plant Microbiome: Harnessing Core Microbiome for Sustainable Agricultures
      While global demand for food is expected to increase significantly (70% by 2050), the agricultural industry is suffering from a decline in soil fertility, the adverse effects of climate chan...
      Speaker: Brajesh Singh
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      3
      SEP 10, 2020 | 9:00 AM
      Congenital Cytomegalovirus - An Unrecognized and Preventable Problem: Fundamentals of Prevention, Diagnosis and Management
      Congenital Cytomegalovirus - An Unrecognized and Preventable Problem:...
      Congenital CMV is the most frequent infectious cause of neonatal malformation in developed nations. It is more prevalent than other neonatal conditions such as spina bifida and Down syndrome...
      Speaker: William Rawlinson, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: Diasorin
      3
      SEP 10, 2020 | 12:00 AM
      A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
      A novel strategy to investigate longitudinal changes within the...
      Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
      Speaker: Candice M. Brown, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Host responses to SARS-CoV-2
      Host responses to SARS-CoV-2
      The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
      Speaker: Angela L. Rasmussen, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 10, 2020 | 12:00 AM
      Long read sequencing of the 16S-23S rRNA operon to characterize gut microbial changes associated with multiple sclerosis
      Long read sequencing of the 16S-23S rRNA operon to characterize...
      The microbiome has emerged as a major contributor to human health and disease. Numerous sources implicate shifts in the gut microbiome as potentially pathologic for a variety of autoimmune d...
      Speaker: Erin Longbrake, MD, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Understanding the role of virus-host interactions in tissue tropism of plant viruses
      Understanding the role of virus-host interactions in tissue tropism...
      To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
      Speaker: Svetlana Y. Folimonova
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 09, 2020 | 12:00 AM
      Lung immune cells as drivers of influenza outcomes
      Lung immune cells as drivers of influenza outcomes
      Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
      Speaker: Juliet Morrison, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Fc gamma receptor activation during viral infections: a double-edged sword
      Fc gamma receptor activation during viral infections: a double-edged...
      Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
      Speaker: Raymond A. Alvarez, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Nanoparticle-based next-generation influenza vaccines
      Nanoparticle-based next-generation influenza vaccines
      Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
      Speaker: Masaru Kanekiyo, DVM, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 01, 2020 | 8:00 AM
      Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
      Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
      DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
      Speaker: Justin Balko
      Sponsored By: Thermo Fisher Scientific
      20 1
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      AUG 11, 2020 | 10:00 AM
      Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
      Better resolution for CE-SDS analysis of new biopharmaceutical...
      DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
      Speaker: Andras Guttman, PhD
      Sponsored By: SCIEX
      9 4
      AUG 07, 2020 | 12:00 PM
      Part IV: How to be a sane clinician scientist - a timeline
      Part IV: How to be a sane clinician scientist - a timeline
      This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
      Speaker: Lois Smith, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 07, 2020 | 12:00 PM
      Part I: Dual Degrees and Dual Careers -- The Interface between Neurology and Neuroscience
      Part I: Dual Degrees and Dual Careers -- The Interface between...
      During this seminar I will present details of my path from Beckman Scholar to MD-PhD, advanced training as a neurologist, then a neurointensivist, and the interleaving of additional research...
      Speaker: Terrance T. Kummer, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 07, 2020 | 9:00 AM
      Part I: The Team, the Generalist, and Seeing Through Blind Spots
      Part I: The Team, the Generalist, and Seeing Through Blind Spots
      I will tell brief stories of experiences that have shaped my career, generalize the lessons learned, and translate them to three actionable items: (1) be careful with your pronouns, (2) embr...
      Speaker: Jeffrey S. Moore, PhD
      Presented at: 2020 Beckman Symposium
      2
      AUG 06, 2020 | 10:00 AM
      Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      Part VII: From biochemical nanosensors to imaging to informatics...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 10:00 AM
      Part IV: SPARC - A method to genetically manipulate precise proportions of cells
      Part IV: SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      2
      AUG 06, 2020 | 12:00 AM
      From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      From biochemical nanosensors to imaging to informatics to COVID-19...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      SPARC - A method to genetically manipulate precise proportions of cells
      SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 29, 2020 | 5:00 PM
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
      Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 2:00 PM
      Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
      Route of 41BB/41BBL costimulation determines effector function...
      B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
      Speaker: Christopher DeRenzo, MD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 1:00 PM
      Using quantitative imaging microscopy to explore and target the molecular origins of cancer
      Using quantitative imaging microscopy to explore and target the...
      The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
      Speaker: Kirk McManus, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
    SEP 16, 2020 | 10:00 AM
    New Crossroad: The Intersection of COVID-19 and Sepsis
    New Crossroad: The Intersection of COVID-19 and Sepsis
    Date: September 16, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Learning Objectives Compare and contrast viral sepsis with focus on sepsis symptoms caused by SARS-CoV- The role of rapid testing f...
    Speaker: Donna Wolk, MHA, PhD, D(ABMM)
    Sponsored By: BD
    16 1
    SEP 11, 2020 | 8:00 AM
    Implementing a World-Class Clinical Pharmacogenomics Service
    Implementing a World-Class Clinical Pharmacogenomics Service
    DATE: September 11, 2020 TIME: 08:00am PT, 11:00pm ET This is the third topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. Pharmacog...
    Speaker: Dr. Hyun Kim
    Sponsored By: Thermo Fisher Scientific/Gibco
    8 2
    SEP 10, 2020 | 3:00 PM
    Plant Microbiome: Harnessing Core Microbiome for Sustainable Agricultures
    Plant Microbiome: Harnessing Core Microbiome for Sustainable Agricultures
    While global demand for food is expected to increase significantly (70% by 2050), the agricultural industry is suffering from a decline in soil fertility, the adverse effects of climate chan...
    Speaker: Brajesh Singh
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    3
    SEP 10, 2020 | 9:00 AM
    Congenital Cytomegalovirus - An Unrecognized and Preventable Problem: Fundamentals of Prevention, Diagnosis and Management
    Congenital Cytomegalovirus - An Unrecognized and Preventable Problem:...
    Congenital CMV is the most frequent infectious cause of neonatal malformation in developed nations. It is more prevalent than other neonatal conditions such as spina bifida and Down syndrome...
    Speaker: William Rawlinson, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: Diasorin
    3
    SEP 10, 2020 | 12:00 AM
    A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
    A novel strategy to investigate longitudinal changes within the...
    Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
    Speaker: Candice M. Brown, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 10, 2020 | 12:00 AM
    Host responses to SARS-CoV-2
    Host responses to SARS-CoV-2
    The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
    Speaker: Angela L. Rasmussen, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 10, 2020 | 12:00 AM
    Long read sequencing of the 16S-23S rRNA operon to characterize gut microbial changes associated with multiple sclerosis
    Long read sequencing of the 16S-23S rRNA operon to characterize...
    The microbiome has emerged as a major contributor to human health and disease. Numerous sources implicate shifts in the gut microbiome as potentially pathologic for a variety of autoimmune d...
    Speaker: Erin Longbrake, MD, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    Understanding the role of virus-host interactions in tissue tropism of plant viruses
    Understanding the role of virus-host interactions in tissue tropism...
    To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
    Speaker: Svetlana Y. Folimonova
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 09, 2020 | 12:00 AM
    Lung immune cells as drivers of influenza outcomes
    Lung immune cells as drivers of influenza outcomes
    Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
    Speaker: Juliet Morrison, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    Fc gamma receptor activation during viral infections: a double-edged sword
    Fc gamma receptor activation during viral infections: a double-edged...
    Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
    Speaker: Raymond A. Alvarez, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 08, 2020 | 11:00 PM
    Nanoparticle-based next-generation influenza vaccines
    Nanoparticle-based next-generation influenza vaccines
    Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
    Speaker: Masaru Kanekiyo, DVM, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 01, 2020 | 8:00 AM
    Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
    Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
    DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
    Speaker: Justin Balko
    Sponsored By: Thermo Fisher Scientific
    20 1
    AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
    AUG 11, 2020 | 10:00 AM
    Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
    Better resolution for CE-SDS analysis of new biopharmaceutical...
    DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
    Speaker: Andras Guttman, PhD
    Sponsored By: SCIEX
    9 4
    AUG 07, 2020 | 12:00 PM
    Part IV: How to be a sane clinician scientist - a timeline
    Part IV: How to be a sane clinician scientist - a timeline
    This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
    Speaker: Lois Smith, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
     
     
  • AUG 07, 2020 | 12:00 PM
    Part I: Dual Degrees and Dual Careers -- The Interface between Neurology and Neuroscience
    Part I: Dual Degrees and Dual Careers -- The Interface between...
    During this seminar I will present details of my path from Beckman Scholar to MD-PhD, advanced training as a neurologist, then a neurointensivist, and the interleaving of additional research...
    Speaker: Terrance T. Kummer, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 07, 2020 | 9:00 AM
    Part I: The Team, the Generalist, and Seeing Through Blind Spots
    Part I: The Team, the Generalist, and Seeing Through Blind Spots
    I will tell brief stories of experiences that have shaped my career, generalize the lessons learned, and translate them to three actionable items: (1) be careful with your pronouns, (2) embr...
    Speaker: Jeffrey S. Moore, PhD
    Presented at: 2020 Beckman Symposium
    2
    AUG 06, 2020 | 10:00 AM
    Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    Part VII: From biochemical nanosensors to imaging to informatics...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 10:00 AM
    Part IV: SPARC - A method to genetically manipulate precise proportions of cells
    Part IV: SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    2
    AUG 06, 2020 | 12:00 AM
    From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    From biochemical nanosensors to imaging to informatics to COVID-19...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
     
     
  • AUG 06, 2020 | 12:00 AM
    SPARC - A method to genetically manipulate precise proportions of cells
    SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 29, 2020 | 5:00 PM
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
    Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 2:00 PM
    Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
    Route of 41BB/41BBL costimulation determines effector function...
    B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
    Speaker: Christopher DeRenzo, MD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 1:00 PM
    Using quantitative imaging microscopy to explore and target the molecular origins of cancer
    Using quantitative imaging microscopy to explore and target the...
    The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
    Speaker: Kirk McManus, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
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