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    ALS

    ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. A-myo-trophic comes from the Greek language. "A" means no. "Myo" refers to muscle, and "Trophic" means nourishment - "No muscle nourishment."

    Webinars

    • JUL 28, 2021 | 7:00 AM
      Population bottlenecks strongly affect the evolutionary dynamics of antibiotic persistence
      Population bottlenecks strongly affect the evolutionary dynamics...
      Date: July 28, 2021 Time: 7:00am PDT Bacterial persistence is a potential cause of antibiotic therapy failure. Antibiotic-tolerant persisters originate from phenotypic differentiation within...
      Speaker: Bram Van den Bergh
      Sponsored By: Inscripta
      5 1
      APR 21, 2021 | 5:00 PM
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
      Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
      Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
      Sponsored By: NanoString Technologies, Illumina
      5
      FEB 24, 2021 | 12:00 AM
      The Comprehensive A.I.-Driven Genomic Landscape for ALS - Implications for Drug Discovery and Development
      The Comprehensive A.I.-Driven Genomic Landscape for ALS - Implications...
      Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease affecting approximately 1 in 50,000 people worldwide. About 10% of these cases are found to have a hereditary component, bu...
      Speaker: Mark Kiel, MD, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      2
      FEB 10, 2021 | 12:00 AM
      The Experimental Design Assistant: an interactive web-based tool to provide bespoke feedback on experimental plans for in vivo studies
      The Experimental Design Assistant: an interactive web-based tool...
      There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
      Speaker: Dr. Esther Pearl
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      2
      FEB 10, 2021 | 12:00 AM
      How to improve rodent aseptic surgery at your facility using household products: Press N' Seal and Reynolds Wrap Foil
      How to improve rodent aseptic surgery at your facility using household...
      Learning Objectives: 1. Methods on how to aseptically use foil (Reynolds Wrap) in rodent surgery 2. Methods on how aseptically use cling film (Press N' Seal) in rodent surgery 3. Long-te...
      Speaker: Raphael A. Malbrue, DVM, MS, CertAqV
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      5
      FEB 10, 2021 | 12:00 AM
      Refining Pain Management for Laboratory Mice
      Refining Pain Management for Laboratory Mice
      Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
      Speaker: Paulin Jirkof, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      4
      DEC 03, 2020 | 10:30 AM
      The Immunology of COVID-19: A dynamic immune signature for prognosis and spatial transcriptomics of lung tissue
      The Immunology of COVID-19: A dynamic immune signature for prognosis...
      The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 20...
      Speaker: Arutha Kulasinghe, PhD , Miguel Muñoz-Ruiz, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      3
      NOV 12, 2020 | 4:30 PM
      Extend your clinical reporting capabilities with QCI services
      Extend your clinical reporting capabilities with QCI services
      With QCI services your clinical lab can enable a seamless fastq to clinical report workflow. We provide services such as cloud based variant calling and automated upload of the data to the Q...
      Speaker: Ajay Athavale
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: QIAGEN
      1
      NOV 12, 2020 | 3:00 PM
      Translating insights into better outcomes: The new QIAseq Human Exome integrated solution
      Translating insights into better outcomes: The new QIAseq Human...
      What if your lab could perform exome sequencing with the same sensitivity and efficiency of targeted sequencing? The new integrated QIAseq Human Exome TR Insights solution from QIAGEN delive...
      Speaker: Brian Dugan, M.S. , Rupert Yip, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: QIAGEN
      1
      NOV 12, 2020 | 1:30 PM
      Covid-19 Testing and the role of Antigen assays today and moving forward
      Covid-19 Testing and the role of Antigen assays today and moving...
      Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
      Speaker: Vincent Streva, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Diasorin
      1
      NOV 12, 2020 | 12:00 PM
      Measuring levels of neutralizing antibodies in SARS CoV-2 infected/recovered and vaccinated individuals using a high-throughput and cost-effective test
      Measuring levels of neutralizing antibodies in SARS CoV-2 infected/recovered...
      As many parts of the northern hemisphere move into the colder months and indoors, SARS CoV-2 has begun a second infection wave that has exceeded the first surge of cases in many global regio...
      Speaker: Sean Taylor, MBA, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: GenScript
      2
      NOV 12, 2020 | 10:30 AM
      Recovery of cfDNA using the QIAsymphony DSP Circulating DNA Kit
      Recovery of cfDNA using the QIAsymphony DSP Circulating DNA Kit
      Cell-free DNA (cfDNA) is a key analyte for liquid biopsy samples. Due to extremely low concentration and high degree of fragmentation, the extraction of cfDNA is technically challenging. Her...
      Speaker: Alexander Wolf, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      NOV 12, 2020 | 9:00 AM
      Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
      Back to Work, School, and Life: Utility of COVID-19 Testing to...
      Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
      Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Thermo Fisher Scientific
      5
      NOV 12, 2020 | 7:30 AM
      Keynote Presentation: Choosing Wisely lab utilization first steps: addressing the low hanging fruit
      Keynote Presentation: Choosing Wisely lab utilization first steps:...
      In 2012, the Choosing Wisely initiative was commenced by the ABIM with numerous societies putting forward lists of overused tests or procedures. The Choosing Wisely movement has spread to nu...
      Speaker: Jeannie Callum, BA, MD, FRCPC
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      1
      NOV 12, 2020 | 6:00 AM
      Standardization with Clinical Digital Pathology - The Ki-67 Case
      Standardization with Clinical Digital Pathology - The Ki-67 Case
      The nuclear proliferation biomarker Ki-67 has multiple potential roles in breast and other cancers, both as a prognostic but also predictive marker. However, several studies have shown that...
      Speaker: Dzenita Omanovic
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Visiopharm®
      1
      NOV 12, 2020 | 12:00 AM
      Clinical utility of concussion injury biomarkers
      Clinical utility of concussion injury biomarkers
      Cases of traumatic brain injury (TBI) have been steadily rising over the past decade with most common causes of injury observed among participants in contact sports, combat military personne...
      Speaker: Paul R. Johnson, PhD, MT(ASCP), DABCC, FAACC
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      1
      NOV 12, 2020 | 12:00 AM
      Using laboratory data to improve health care delivery and patient outcomes
      Using laboratory data to improve health care delivery and patient...
      Patient laboratory test results are significantly over-represented in electronic medical records, but significantly under-utilized in research. An important application of laboratory data is...
      Speaker: Lawrence de Koning, PhD DABCC FAACC FCACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      2
      NOV 12, 2020 | 12:00 AM
      Laboratory Testing for Opioids
      Laboratory Testing for Opioids
      The opioid crisis has put significant strain on the healthcare system and resources, including the clinical laboratory which has seen significant increases in requests for urine drug screeni...
      Speaker: Jessica Boyd, PhD, FCACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      1
      NOV 12, 2020 | 12:00 AM
      Demonstrating the Value of Laboratory Medicine through Population Health
      Demonstrating the Value of Laboratory Medicine through Population...
      Clinical Laboratories have the opportunity to support value based health care by aligning with organizational strategies that focus on population health and creating meaningful insights usin...
      Speaker: Kathleen Swanson, M.S., R.Ph.
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      1
      NOV 12, 2020 | 12:00 AM
      Portable and Wearable Medical Devices: A Nanotechnology Approach
      Portable and Wearable Medical Devices: A Nanotechnology Approach
      Point-of-care testing (POCT) is destined to play a much greater role in chronic disease diagnosis and management. Advanced POCT systems are being developed to deliver less costly and more ac...
      Speaker: Xiaowu (Shirley) Tang, PhD, PEng
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
      Applying targeted long-read sequencing to assess an expanded repeat...
      A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
      Speaker: Marka van Blitterswijk, MD, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 23, 2020 | 1:30 PM
      Keynote Presentation: Starting at the source: tissue extracellular vesicles and Alzheimer's disease
      Keynote Presentation: Starting at the source: tissue extracellular...
      Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
      Speaker: Kenneth W. Witwer, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      Deep learning to integrate histology with spatial transcriptomics
      Deep learning to integrate histology with spatial transcriptomics
      I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
      Speaker: James Zou
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 17, 2020 | 4:30 PM
      COVID-19 T-Cell Data: Mapping Out SARS-CoV-2 Antigen & T-Cell Repertoires
      COVID-19 T-Cell Data: Mapping Out SARS-CoV-2 Antigen & T-Cell...
      T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, and also support the development of...
      Speaker: Sean Nolan , Patrick Raber, PhD , Thomas Snyder, PhD
      Presented at: Coronavirus Series
      Sponsored By: Adaptive Biotechnologies
      6
    JUL 28, 2021 | 7:00 AM
    Population bottlenecks strongly affect the evolutionary dynamics of antibiotic persistence
    Population bottlenecks strongly affect the evolutionary dynamics...
    Date: July 28, 2021 Time: 7:00am PDT Bacterial persistence is a potential cause of antibiotic therapy failure. Antibiotic-tolerant persisters originate from phenotypic differentiation within...
    Speaker: Bram Van den Bergh
    Sponsored By: Inscripta
    5 1
    APR 21, 2021 | 5:00 PM
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
    Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
    Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
    Sponsored By: NanoString Technologies, Illumina
    5
    FEB 24, 2021 | 12:00 AM
    The Comprehensive A.I.-Driven Genomic Landscape for ALS - Implications for Drug Discovery and Development
    The Comprehensive A.I.-Driven Genomic Landscape for ALS - Implications...
    Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease affecting approximately 1 in 50,000 people worldwide. About 10% of these cases are found to have a hereditary component, bu...
    Speaker: Mark Kiel, MD, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    2
    FEB 10, 2021 | 12:00 AM
    The Experimental Design Assistant: an interactive web-based tool to provide bespoke feedback on experimental plans for in vivo studies
    The Experimental Design Assistant: an interactive web-based tool...
    There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
    Speaker: Dr. Esther Pearl
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    2
    FEB 10, 2021 | 12:00 AM
    How to improve rodent aseptic surgery at your facility using household products: Press N' Seal and Reynolds Wrap Foil
    How to improve rodent aseptic surgery at your facility using household...
    Learning Objectives: 1. Methods on how to aseptically use foil (Reynolds Wrap) in rodent surgery 2. Methods on how aseptically use cling film (Press N' Seal) in rodent surgery 3. Long-te...
    Speaker: Raphael A. Malbrue, DVM, MS, CertAqV
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    5
     
     
  • FEB 10, 2021 | 12:00 AM
    Refining Pain Management for Laboratory Mice
    Refining Pain Management for Laboratory Mice
    Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
    Speaker: Paulin Jirkof, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    4
    DEC 03, 2020 | 10:30 AM
    The Immunology of COVID-19: A dynamic immune signature for prognosis and spatial transcriptomics of lung tissue
    The Immunology of COVID-19: A dynamic immune signature for prognosis...
    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 20...
    Speaker: Arutha Kulasinghe, PhD , Miguel Muñoz-Ruiz, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    3
    NOV 12, 2020 | 4:30 PM
    Extend your clinical reporting capabilities with QCI services
    Extend your clinical reporting capabilities with QCI services
    With QCI services your clinical lab can enable a seamless fastq to clinical report workflow. We provide services such as cloud based variant calling and automated upload of the data to the Q...
    Speaker: Ajay Athavale
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: QIAGEN
    1
    NOV 12, 2020 | 3:00 PM
    Translating insights into better outcomes: The new QIAseq Human Exome integrated solution
    Translating insights into better outcomes: The new QIAseq Human...
    What if your lab could perform exome sequencing with the same sensitivity and efficiency of targeted sequencing? The new integrated QIAseq Human Exome TR Insights solution from QIAGEN delive...
    Speaker: Brian Dugan, M.S. , Rupert Yip, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: QIAGEN
    1
    NOV 12, 2020 | 1:30 PM
    Covid-19 Testing and the role of Antigen assays today and moving forward
    Covid-19 Testing and the role of Antigen assays today and moving...
    Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
    Speaker: Vincent Streva, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Diasorin
    1
     
     
  • NOV 12, 2020 | 12:00 PM
    Measuring levels of neutralizing antibodies in SARS CoV-2 infected/recovered and vaccinated individuals using a high-throughput and cost-effective test
    Measuring levels of neutralizing antibodies in SARS CoV-2 infected/recovered...
    As many parts of the northern hemisphere move into the colder months and indoors, SARS CoV-2 has begun a second infection wave that has exceeded the first surge of cases in many global regio...
    Speaker: Sean Taylor, MBA, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: GenScript
    2
    NOV 12, 2020 | 10:30 AM
    Recovery of cfDNA using the QIAsymphony DSP Circulating DNA Kit
    Recovery of cfDNA using the QIAsymphony DSP Circulating DNA Kit
    Cell-free DNA (cfDNA) is a key analyte for liquid biopsy samples. Due to extremely low concentration and high degree of fragmentation, the extraction of cfDNA is technically challenging. Her...
    Speaker: Alexander Wolf, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    NOV 12, 2020 | 9:00 AM
    Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
    Back to Work, School, and Life: Utility of COVID-19 Testing to...
    Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
    Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Thermo Fisher Scientific
    5
    NOV 12, 2020 | 7:30 AM
    Keynote Presentation: Choosing Wisely lab utilization first steps: addressing the low hanging fruit
    Keynote Presentation: Choosing Wisely lab utilization first steps:...
    In 2012, the Choosing Wisely initiative was commenced by the ABIM with numerous societies putting forward lists of overused tests or procedures. The Choosing Wisely movement has spread to nu...
    Speaker: Jeannie Callum, BA, MD, FRCPC
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    1
    NOV 12, 2020 | 6:00 AM
    Standardization with Clinical Digital Pathology - The Ki-67 Case
    Standardization with Clinical Digital Pathology - The Ki-67 Case
    The nuclear proliferation biomarker Ki-67 has multiple potential roles in breast and other cancers, both as a prognostic but also predictive marker. However, several studies have shown that...
    Speaker: Dzenita Omanovic
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Visiopharm®
    1
     
     
  • NOV 12, 2020 | 12:00 AM
    Clinical utility of concussion injury biomarkers
    Clinical utility of concussion injury biomarkers
    Cases of traumatic brain injury (TBI) have been steadily rising over the past decade with most common causes of injury observed among participants in contact sports, combat military personne...
    Speaker: Paul R. Johnson, PhD, MT(ASCP), DABCC, FAACC
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    1
    NOV 12, 2020 | 12:00 AM
    Using laboratory data to improve health care delivery and patient outcomes
    Using laboratory data to improve health care delivery and patient...
    Patient laboratory test results are significantly over-represented in electronic medical records, but significantly under-utilized in research. An important application of laboratory data is...
    Speaker: Lawrence de Koning, PhD DABCC FAACC FCACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    2
    NOV 12, 2020 | 12:00 AM
    Laboratory Testing for Opioids
    Laboratory Testing for Opioids
    The opioid crisis has put significant strain on the healthcare system and resources, including the clinical laboratory which has seen significant increases in requests for urine drug screeni...
    Speaker: Jessica Boyd, PhD, FCACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    1
    NOV 12, 2020 | 12:00 AM
    Demonstrating the Value of Laboratory Medicine through Population Health
    Demonstrating the Value of Laboratory Medicine through Population...
    Clinical Laboratories have the opportunity to support value based health care by aligning with organizational strategies that focus on population health and creating meaningful insights usin...
    Speaker: Kathleen Swanson, M.S., R.Ph.
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    1
    NOV 12, 2020 | 12:00 AM
    Portable and Wearable Medical Devices: A Nanotechnology Approach
    Portable and Wearable Medical Devices: A Nanotechnology Approach
    Point-of-care testing (POCT) is destined to play a much greater role in chronic disease diagnosis and management. Advanced POCT systems are being developed to deliver less costly and more ac...
    Speaker: Xiaowu (Shirley) Tang, PhD, PEng
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    2
     
     
  • SEP 30, 2020 | 12:00 AM
    Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
    Applying targeted long-read sequencing to assess an expanded repeat...
    A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
    Speaker: Marka van Blitterswijk, MD, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 23, 2020 | 1:30 PM
    Keynote Presentation: Starting at the source: tissue extracellular vesicles and Alzheimer's disease
    Keynote Presentation: Starting at the source: tissue extracellular...
    Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
    Speaker: Kenneth W. Witwer, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 12:00 AM
    Deep learning to integrate histology with spatial transcriptomics
    Deep learning to integrate histology with spatial transcriptomics
    I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
    Speaker: James Zou
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 17, 2020 | 4:30 PM
    COVID-19 T-Cell Data: Mapping Out SARS-CoV-2 Antigen & T-Cell Repertoires
    COVID-19 T-Cell Data: Mapping Out SARS-CoV-2 Antigen & T-Cell...
    T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, and also support the development of...
    Speaker: Sean Nolan , Patrick Raber, PhD , Thomas Snyder, PhD
    Presented at: Coronavirus Series
    Sponsored By: Adaptive Biotechnologies
    6
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