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    Biomarkers

    Biomarkers: a biomarker, or biological marker, generally refers to a measurable indicator of some biological state or condition. The term is also occasionally used to refer to a substance, the presence of which indicates the existence of a living organism. Further, life forms are known to shed unique chemicals, including DNA, into the environment as evidence of their presence in a particular location.

    Webinars

    • MAR 13, 2019 | 8:00 AM
      BRAIN Initiative Scientific Updates: Deciphering the Neuronal Mechanisms of Human Episodic Memory at the Single-Neuron Level
      BRAIN Initiative Scientific Updates: Deciphering the Neuronal...
      The rapid formation of new memories and the recall of old memories to inform decisions is essential for human cognition, but the underlying neural mechanisms remain poorly understood. We util...
      Speaker: Ueli Rutishauser, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      1
      MAR 13, 2019 | 7:40 AM
      BRAIN Initiative Scientific Updates: How the Human Brain Learns to Learn
      BRAIN Initiative Scientific Updates: How the Human Brain Learns...
      The human brain has a remarkable ability to store and retrieve information. Detailed memories can be formed after as little as one exposure, and those memories can be retained for decades. Im...
      Speaker: Elizabeth Buffalo, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      2
      MAR 13, 2019 | 7:00 AM
      NIH BRAIN Funding Opportunities: NIH BRAIN Initiative and Functional Human Neuroscience
      NIH BRAIN Funding Opportunities: NIH BRAIN Initiative and Functional...
      NIH representatives from the BRAIN Initiative will be presenting an overview of the NIH BRAIN Initiative and describing funding opportunity announcements (FOAs) supporting impacts in human ne...
      Speaker: James Gnadt, PhD , Karen David, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      1
      MAR 13, 2019 | 6:00 AM
      Keynote Presentation: Updates from the NIH BRAIN Initiative
      Keynote Presentation: Updates from the NIH BRAIN Initiative
      Joshua Gordon, M.D., Ph.D., Director of the National Institute of Mental Health, will provide an overview of challenges and opportunities in mental health research. Dr. Gordon will present em...
      Speaker: Joshua A. Gordon, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      3
      MAR 05, 2019 | 10:00 AM
      Comprehensive Capture of Human Neuropathology by Multiplexed Ion Beam Imaging (MIBI)
      Comprehensive Capture of Human Neuropathology by Multiplexed Ion...
      DATE: March 5, 2019TIME:  10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
      Speaker: Sean Bendall, PhD
      Sponsored By: IONpath
      2 1
      MAR 05, 2019 | 9:00 AM
      Strategies to normalize miRNA expression in serum and plasma.
      Strategies to normalize miRNA expression in serum and plasma.
      DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
      Speaker: Emily Zeringer , Harita Veereshlingam, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      7
      FEB 27, 2019 | 3:00 PM
      BASKET Trials: Biomarker Driven Drug Development
      BASKET Trials: Biomarker Driven Drug Development
      Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
      Speaker: Shivaani Kummar, MD, FACP
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 1:30 PM
      Aptamers in Drug Development: From Biomarker Discovery to Targeted Drug Delivery to Small Molecule Drug Detection
      Aptamers in Drug Development: From Biomarker Discovery to Targeted...
      Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
      Speaker: Bill Jackson, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 1:30 PM
      Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
      Advances in Three-Dimensional Cell Culture in Drug Research and...
      Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
      Speaker: Richard Eglen, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 1:30 PM
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
      NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
      Speaker: Phillip Febbo, MD , Maude Champagne
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Illumina
      4
      FEB 27, 2019 | 12:00 PM
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
      Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      FEB 27, 2019 | 12:00 PM
      Studies on Malignancies With a Novel Proliferation Biomarker
      Studies on Malignancies With a Novel Proliferation Biomarker
      Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
      Speaker: Martin Shaw
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      FEB 27, 2019 | 10:30 AM
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
      Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
      An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
      Speaker: G. Thomas Caltagirone, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 6:00 AM
      Biomarkers of Aging
      Biomarkers of Aging
      Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
      Speaker: Alex Zhavoronkov, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 6:00 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      FEB 26, 2019 | 11:00 AM
      Osteosarcoma research
      Osteosarcoma research
      DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
      Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      FEB 13, 2019 | 1:30 PM
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
      Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
      Speaker: Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5
      JAN 29, 2019 | 9:00 AM
      Targeting prostate cancer stem cells with T cell immunotherapy
      Targeting prostate cancer stem cells with T cell immunotherapy
      DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
      Speaker: Amy Codd
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      DEC 18, 2018 | 5:00 AM
      Risk stratification of the apparently healthy population with ARCHITECT STAT High Sensitive Troponin-I
      Risk stratification of the apparently healthy population with...
      DATE:    December 18, 2018TIME:    7:00am CST, 8:00am EST In this webinar you will hear about a recently CE marked application for ARCHITECT STA...
      Speaker: Gillian Murtagh, MD
      Sponsored By: Abbott
      8 2
      DEC 06, 2018 | 6:00 AM
      Overview of the main hormones associated with alteration of bone and mineral metabolism in patients with chronic kidney disease
      Overview of the main hormones associated with alteration of bone...
      DATE: December 6, 2018TIME:6:00am PST, 9:00am EST, 3:00pm CET Alterations in the bone and mineral...
      Speaker: Jean-Claude Souberbielle (JCS)
      Sponsored By: Diasorin
      7
      DEC 05, 2018 | 8:00 PM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      5 3
      DEC 05, 2018 | 9:00 AM
      Making the most of your mouse model with bead-based multiplexing
      Making the most of your mouse model with bead-based multiplexing
      DATE: December 5, 2018TIME: 9:00AM PDTThe mouse is a critical, increasingly used model system in biomedical research and preclinical drug discovery. While technological advances en...
      Speaker: Daniel Braunschweig, PhD
      Sponsored By: Luminex
      2
      DEC 05, 2018 | 7:00 AM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      7
    MAR 13, 2019 | 8:00 AM
    BRAIN Initiative Scientific Updates: Deciphering the Neuronal Mechanisms of Human Episodic Memory at the Single-Neuron Level
    BRAIN Initiative Scientific Updates: Deciphering the Neuronal...
    The rapid formation of new memories and the recall of old memories to inform decisions is essential for human cognition, but the underlying neural mechanisms remain poorly understood. We util...
    Speaker: Ueli Rutishauser, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    1
    MAR 13, 2019 | 7:40 AM
    BRAIN Initiative Scientific Updates: How the Human Brain Learns to Learn
    BRAIN Initiative Scientific Updates: How the Human Brain Learns...
    The human brain has a remarkable ability to store and retrieve information. Detailed memories can be formed after as little as one exposure, and those memories can be retained for decades. Im...
    Speaker: Elizabeth Buffalo, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    2
    MAR 13, 2019 | 7:00 AM
    NIH BRAIN Funding Opportunities: NIH BRAIN Initiative and Functional Human Neuroscience
    NIH BRAIN Funding Opportunities: NIH BRAIN Initiative and Functional...
    NIH representatives from the BRAIN Initiative will be presenting an overview of the NIH BRAIN Initiative and describing funding opportunity announcements (FOAs) supporting impacts in human ne...
    Speaker: James Gnadt, PhD , Karen David, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    1
    MAR 13, 2019 | 6:00 AM
    Keynote Presentation: Updates from the NIH BRAIN Initiative
    Keynote Presentation: Updates from the NIH BRAIN Initiative
    Joshua Gordon, M.D., Ph.D., Director of the National Institute of Mental Health, will provide an overview of challenges and opportunities in mental health research. Dr. Gordon will present em...
    Speaker: Joshua A. Gordon, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    3
    MAR 05, 2019 | 10:00 AM
    Comprehensive Capture of Human Neuropathology by Multiplexed Ion Beam Imaging (MIBI)
    Comprehensive Capture of Human Neuropathology by Multiplexed Ion...
    DATE: March 5, 2019TIME:  10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
    Speaker: Sean Bendall, PhD
    Sponsored By: IONpath
    2 1
     
     
  • MAR 05, 2019 | 9:00 AM
    Strategies to normalize miRNA expression in serum and plasma.
    Strategies to normalize miRNA expression in serum and plasma.
    DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
    Speaker: Emily Zeringer , Harita Veereshlingam, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    7
    FEB 27, 2019 | 3:00 PM
    BASKET Trials: Biomarker Driven Drug Development
    BASKET Trials: Biomarker Driven Drug Development
    Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
    Speaker: Shivaani Kummar, MD, FACP
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 1:30 PM
    Aptamers in Drug Development: From Biomarker Discovery to Targeted Drug Delivery to Small Molecule Drug Detection
    Aptamers in Drug Development: From Biomarker Discovery to Targeted...
    Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
    Speaker: Bill Jackson, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 1:30 PM
    Advances in Three-Dimensional Cell Culture in Drug Research and Discovery
    Advances in Three-Dimensional Cell Culture in Drug Research and...
    Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
    Speaker: Richard Eglen, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 1:30 PM
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
    NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
    Speaker: Phillip Febbo, MD , Maude Champagne
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Illumina
    4
     
     
  • FEB 27, 2019 | 12:00 PM
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
    Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    FEB 27, 2019 | 12:00 PM
    Studies on Malignancies With a Novel Proliferation Biomarker
    Studies on Malignancies With a Novel Proliferation Biomarker
    Studies in drug development and on hematological and solid Tumors with a Thymidine Kinase 1 immunoassayThere are many tumor biomarkers but, they mostly reflect tumor mass or past growth,...
    Speaker: Martin Shaw
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
    FEB 27, 2019 | 10:30 AM
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics and Drug Discovery
    Synthetic Antibodies - The Emerging Field of "Aptamers" in Diagnostics...
    An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
    Speaker: G. Thomas Caltagirone, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 6:00 AM
    Biomarkers of Aging
    Biomarkers of Aging
    Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
    Speaker: Alex Zhavoronkov, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
     
     
  • FEB 27, 2019 | 6:00 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    FEB 26, 2019 | 11:00 AM
    Osteosarcoma research
    Osteosarcoma research
    DATE:  February 26, 2019TIME:  11:00am PST, 2:00pm EST Osteosarcoma is the most common type of primary bone cancer affecting adolescents and children attributed to...
    Speaker: Luke Tattersall, BSc Biomedical Sciences, PhD Candidate
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    FEB 13, 2019 | 1:30 PM
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
    Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
    Speaker: Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5
    JAN 29, 2019 | 9:00 AM
    Targeting prostate cancer stem cells with T cell immunotherapy
    Targeting prostate cancer stem cells with T cell immunotherapy
    DATE:    January 29. 2019TIME:    09:00am PST, 12:00pm EST In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simul...
    Speaker: Amy Codd
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
    DEC 18, 2018 | 5:00 AM
    Risk stratification of the apparently healthy population with ARCHITECT STAT High Sensitive Troponin-I
    Risk stratification of the apparently healthy population with...
    DATE:    December 18, 2018TIME:    7:00am CST, 8:00am EST In this webinar you will hear about a recently CE marked application for ARCHITECT STA...
    Speaker: Gillian Murtagh, MD
    Sponsored By: Abbott
    8 2
     
     
  • DEC 06, 2018 | 6:00 AM
    Overview of the main hormones associated with alteration of bone and mineral metabolism in patients with chronic kidney disease
    Overview of the main hormones associated with alteration of bone...
    DATE: December 6, 2018TIME:6:00am PST, 9:00am EST, 3:00pm CET Alterations in the bone and mineral...
    Speaker: Jean-Claude Souberbielle (JCS)
    Sponsored By: Diasorin
    7
    DEC 05, 2018 | 8:00 PM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
    5 3
    DEC 05, 2018 | 9:00 AM
    Making the most of your mouse model with bead-based multiplexing
    Making the most of your mouse model with bead-based multiplexing
    DATE: December 5, 2018TIME: 9:00AM PDTThe mouse is a critical, increasingly used model system in biomedical research and preclinical drug discovery. While technological advances en...
    Speaker: Daniel Braunschweig, PhD
    Sponsored By: Luminex
    2
    DEC 05, 2018 | 7:00 AM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
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