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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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SEP 22, 2016Genetics & Genomics
Most people take for granted that they can walk down the street while thinking about their day. Or drive to work without ...Written By: Jennifer EllisSEP 21, 2016Clinical & Molecular DX
Powerful New Research Tool Reveals How Tecfidera® Blocks T-Cell Activation LA JOLLA, CA—September 21, 2016&mda ...Written By: The Scripps Research Institute (TSRI)SEP 18, 2016Cell & Molecular Biology
Researchers have created a new, fluorescent probe that detects a specific methyl group on histones in living cells. This ...Written By: Carmen LeitchSEP 17, 2016Cell & Molecular Biology
Benign prostatic hyperplasia (BPH) affects nearly half of all men aged 51 - 60 and 90 percent of men older than 80 years ...Written By: Carmen LeitchSEP 16, 2016Microbiology
Pathogenic microbes can cause serious damage to our intestinal lining that must be repaired by our body. New research pu ...Written By: Carmen LeitchSEP 16, 2016Health & Medicine
LA JOLLA, CA—September 16, 2016—Scientists at The Scripps Research Institute (TSRI) have discovered a potent ...Written By: The Scripps Research Institute (TSRI)SEP 14, 2016Cancer
DNA mutations that cause mutations get a lot of press. But problems with RNA and proteins can also lead to cancer. Shedd ...SEP 14, 2016Cell & Molecular Biology
A parthenogenote is derived from an unfertilized egg. Mammalian parthenogenotes are haploid, meaning they have only one ...Written By: Carmen LeitchSEP 13, 2016Clinical & Molecular DX
Not all fat are bad – brown fat actually act as fuel for the body to stay warm and maintain healthy weights. Now, ...SEP 12, 2016Microbiology
The first month of a newborn’s life is so critical to a lifetime of health that this period has a name: neonate. I ...Written By: Kara MarkerSEP 12, 2016Genetics & Genomics
Dana Farber/Boston Children's has been able to selectively silence a gene, BCL11A, found in 2008 to be an integral part ...Written By: Jennifer EllisSEP 11, 2016Cell & Molecular Biology
Junk DNA refers to regions of the genome that did not at first appear to have any function or relevance. Research over t ...Written By: Carmen LeitchSEP 10, 2016Cell & Molecular Biology
Heat shock proteins are known to help the body respond to stress, but new research appears to implicate one of them, Hsp ...Written By: Carmen LeitchSEP 09, 2016Immunology
Food allergies, especially in children, are becoming more and more at the center of different kinds of research: immunol ...Written By: Kara MarkerSEP 09, 2016Clinical & Molecular DX
Steroids that could help women get pregnant may, ironically, be responsible for miscarriage, preterm birth, and birth de ...SEP 08, 2016Health & Medicine
LA JOLLA, CA – September 8, 2016 – A series of new studies led by scientists at The Scripps Research Institu ...Written By: The Scripps Research Institute (TSRI)SEP 08, 2016Cell & Molecular Biology
Stuff in our world is made up of matter, composed of atoms, which means that everything is basically a chemical. But som ...Written By: Carmen LeitchSEP 08, 2016Neuroscience
In the millions of years of evolution, humans developed strong muscles for hunting and gathering, digestion to get the m ...Written By: Brenda Kelley KimSEP 07, 2016Cell & Molecular Biology
Aging has long been a bane of human existence and people seem to have tried everything to delay or stop it. Resear ...Written By: Carmen LeitchSEP 05, 2016Microbiology
A new microscopy technique has allowed researchers at the University of Maryland School of Medicine (UM SOM) to take dir ...Written By: Carmen LeitchSEP 04, 2016Microbiology
Most bacteria have flagella; they are threadlike appendages extending from the surface of many microbes. They help move ...Written By: Carmen LeitchSEP 03, 2016Plants & Animals
Identical twin formation in humans seem to fascinate the masses. To our brains, which are programmed to see everyone dif ...Written By: Anthony BouchardSEP 02, 2016Cancer
Vitamins are once again in the spotlight this week. This time, researchers at Stanford University found a link between v ...SEP 02, 2016Cell & Molecular Biology
Pluripotent stem cells can form into any cell type in the human body through the process of normal human development. Cr ...Written By: Carmen Leitch
SEP 22, 2016
Genetics & Genomics
Most people take for granted that they can walk down the street while thinking about their day. Or drive to work without
...
Written By:
Jennifer Ellis
SEP 21, 2016
Clinical & Molecular DX
Powerful New Research Tool Reveals How Tecfidera® Blocks T-Cell Activation LA JOLLA, CA—September 21, 2016&mda
...
Written By:
The Scripps Research Institute (TSRI)
SEP 18, 2016
Cell & Molecular Biology
Researchers have created a new, fluorescent probe that detects a specific methyl group on histones in living cells. This
...
Written By:
Carmen Leitch
SEP 17, 2016
Cell & Molecular Biology
Benign prostatic hyperplasia (BPH) affects nearly half of all men aged 51 - 60 and 90 percent of men older than 80 years
...
Written By:
Carmen Leitch
SEP 16, 2016
Microbiology
Pathogenic microbes can cause serious damage to our intestinal lining that must be repaired by our body. New research pu
...
Written By:
Carmen Leitch
SEP 16, 2016
Health & Medicine
LA JOLLA, CA—September 16, 2016—Scientists at The Scripps Research Institute (TSRI) have discovered a potent
...
Written By:
The Scripps Research Institute (TSRI)
SEP 14, 2016
Cancer
DNA mutations that cause mutations get a lot of press. But problems with RNA and proteins can also lead to cancer. Shedd
...
SEP 14, 2016
Cell & Molecular Biology
A parthenogenote is derived from an unfertilized egg. Mammalian parthenogenotes are haploid, meaning they have only one
...
Written By:
Carmen Leitch
SEP 13, 2016
Clinical & Molecular DX
Not all fat are bad – brown fat actually act as fuel for the body to stay warm and maintain healthy weights. Now,
...
SEP 12, 2016
Microbiology
The first month of a newborn’s life is so critical to a lifetime of health that this period has a name: neonate. I
...
Written By:
Kara Marker
SEP 12, 2016
Genetics & Genomics
Dana Farber/Boston Children's has been able to selectively silence a gene, BCL11A, found in 2008 to be an integral part
...
Written By:
Jennifer Ellis
SEP 11, 2016
Cell & Molecular Biology
Junk DNA refers to regions of the genome that did not at first appear to have any function or relevance. Research over t
...
Written By:
Carmen Leitch
SEP 10, 2016
Cell & Molecular Biology
Heat shock proteins are known to help the body respond to stress, but new research appears to implicate one of them, Hsp
...
Written By:
Carmen Leitch
SEP 09, 2016
Immunology
Food allergies, especially in children, are becoming more and more at the center of different kinds of research: immunol
...
Written By:
Kara Marker
SEP 09, 2016
Clinical & Molecular DX
Steroids that could help women get pregnant may, ironically, be responsible for miscarriage, preterm birth, and birth de
...
SEP 08, 2016
Health & Medicine
LA JOLLA, CA – September 8, 2016 – A series of new studies led by scientists at The Scripps Research Institu
...
Written By:
The Scripps Research Institute (TSRI)
SEP 08, 2016
Cell & Molecular Biology
Stuff in our world is made up of matter, composed of atoms, which means that everything is basically a chemical. But som
...
Written By:
Carmen Leitch
SEP 08, 2016
Neuroscience
In the millions of years of evolution, humans developed strong muscles for hunting and gathering, digestion to get the m
...
Written By:
Brenda Kelley Kim
SEP 07, 2016
Cell & Molecular Biology
Aging has long been a bane of human existence and people seem to have tried everything to delay or stop it. Resear
...
Written By:
Carmen Leitch
SEP 05, 2016
Microbiology
A new microscopy technique has allowed researchers at the University of Maryland School of Medicine (UM SOM) to take dir
...
Written By:
Carmen Leitch
SEP 04, 2016
Microbiology
Most bacteria have flagella; they are threadlike appendages extending from the surface of many microbes. They help move
...
Written By:
Carmen Leitch
SEP 03, 2016
Plants & Animals
Identical twin formation in humans seem to fascinate the masses. To our brains, which are programmed to see everyone dif
...
Written By:
Anthony Bouchard
SEP 02, 2016
Cancer
Vitamins are once again in the spotlight this week. This time, researchers at Stanford University found a link between v
...
SEP 02, 2016
Cell & Molecular Biology
Pluripotent stem cells can form into any cell type in the human body through the process of normal human development. Cr
...
Written By:
Carmen Leitch