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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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OCT 12, 2016Cardiology
Scientists are unraveling the molecular mechanisms behind dilated cardiomyopathy (DCM), the most common inherited diseas ...Written By: Kara MarkerOCT 12, 2016Immunology
The key ingredient in the recipe that make staphylococcus and streptococcus infections so dangerous? Superantigen toxins ...Written By: Kara MarkerOCT 11, 2016Clinical & Molecular DX
Each year, health officials zealously launch flu shot campaigns, aimed at vaccinating people against the influenza virus ...OCT 10, 2016Immunology
One small change in the chromosomes of B lymphocytes, and the immune cells cannot proliferate and create antibodies to f ...Written By: Kara MarkerOCT 09, 2016Cell & Molecular Biology
Vitamin D deficiency impacts millions of men, women and children globally. Children that are born with very low levels o ...Written By: Carmen LeitchOCT 09, 2016Cell & Molecular Biology
If you’re familiar with the word prion than you probably associate it with dysfunction and disease. Prions infamou ...Written By: Carmen LeitchOCT 07, 2016Cell & Molecular Biology
Researchers have discovered that some proteins that have an influence on the progression and metastasis of cancer are st ...Written By: Carmen LeitchOCT 07, 2016Cell & Molecular Biology
Model organisms are vital to scientific research. They provide researchers with a way to analyze biochemical events in v ...Written By: Carmen LeitchOCT 06, 2016Cell & Molecular Biology
Recent work in the Journal of Molecular Biology has described how advances in technology and biology could produce a thr ...Written By: Carmen LeitchOCT 05, 2016Immunology
While scientists know that there is some genetic connection that explains why some people develop psoriasis, little is k ...Written By: Kara MarkerOCT 05, 2016Cell & Molecular Biology
A powerful new microscopy tool has been created by researchers working at the Marine Biological Laboratory (MBL) capable ...Written By: Carmen LeitchOCT 04, 2016Cancer
A controversial study last year rocked the foundation of cancer and health research, suggesting that cancer was merely j ...OCT 04, 2016Genetics & Genomics
Stabilizing the Ultimate Tumor Suppressor p53Written By: Jennifer EllisOCT 04, 2016Cell & Molecular Biology
The 2016 Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi for his influential work inves ...Written By: Carmen LeitchOCT 04, 2016Neuroscience
Chronic traumatic encephalopathy (CTE) is a neurodegenerative brain disease that has gotten a lot of attention in the pr ...Written By: Brenda Kelley KimOCT 03, 2016Cell & Molecular Biology
To put it simply, organisms inherit a copy of each gene from each parent. For a small group of genes, roughly one hundre ...Written By: Carmen LeitchSEP 30, 2016Cell & Molecular Biology
Our DNA uses messenger RNA or mRNA as the intermediary that directs cellular machinery to construct the many various pro ...Written By: Carmen LeitchSEP 28, 2016Immunology
A diet high in fat from specific sources is uniquely responsible for contributing to intestinal cancer through promoting ...Written By: Kara MarkerSEP 28, 2016Cell & Molecular Biology
Every cell in our body contains DNA, and that genomic material is critical to our health. One threat to the double stran ...Written By: Carmen LeitchSEP 27, 2016Cell & Molecular Biology
Cell Regeneration in Your Eyes Could Treat Retinal Blindness DiseasesWritten By: Jennifer EllisSEP 27, 2016Neuroscience
The developing brain is both a mystery and a miracle. While there is new information every day about how our brains deve ...Written By: Brenda Kelley KimSEP 25, 2016Cell & Molecular Biology
In the natural world, genes don’t always operate independently. They can function as part of a set of genes and ca ...Written By: Carmen LeitchSEP 23, 2016Chemistry & Physics
Methanol is one of the world’s most widely used chemicals, and has been since the 1800’s. It is used to make ...Written By: Jennifer EllisSEP 22, 2016Cell & Molecular Biology
Researchers at the Agency for Science, Technology and Research (A*STAR), Singapore, have shown that alterations in regul ...Written By: Carmen Leitch
OCT 12, 2016
Cardiology
Scientists are unraveling the molecular mechanisms behind dilated cardiomyopathy (DCM), the most common inherited diseas
...
Written By:
Kara Marker
OCT 12, 2016
Immunology
The key ingredient in the recipe that make staphylococcus and streptococcus infections so dangerous? Superantigen toxins
...
Written By:
Kara Marker
OCT 11, 2016
Clinical & Molecular DX
Each year, health officials zealously launch flu shot campaigns, aimed at vaccinating people against the influenza virus
...
OCT 10, 2016
Immunology
One small change in the chromosomes of B lymphocytes, and the immune cells cannot proliferate and create antibodies to f
...
Written By:
Kara Marker
OCT 09, 2016
Cell & Molecular Biology
Vitamin D deficiency impacts millions of men, women and children globally. Children that are born with very low levels o
...
Written By:
Carmen Leitch
OCT 09, 2016
Cell & Molecular Biology
If you’re familiar with the word prion than you probably associate it with dysfunction and disease. Prions infamou
...
Written By:
Carmen Leitch
OCT 07, 2016
Cell & Molecular Biology
Researchers have discovered that some proteins that have an influence on the progression and metastasis of cancer are st
...
Written By:
Carmen Leitch
OCT 07, 2016
Cell & Molecular Biology
Model organisms are vital to scientific research. They provide researchers with a way to analyze biochemical events in v
...
Written By:
Carmen Leitch
OCT 06, 2016
Cell & Molecular Biology
Recent work in the Journal of Molecular Biology has described how advances in technology and biology could produce a thr
...
Written By:
Carmen Leitch
OCT 05, 2016
Immunology
While scientists know that there is some genetic connection that explains why some people develop psoriasis, little is k
...
Written By:
Kara Marker
OCT 05, 2016
Cell & Molecular Biology
A powerful new microscopy tool has been created by researchers working at the Marine Biological Laboratory (MBL) capable
...
Written By:
Carmen Leitch
OCT 04, 2016
Cancer
A controversial study last year rocked the foundation of cancer and health research, suggesting that cancer was merely j
...
OCT 04, 2016
Genetics & Genomics
Stabilizing the Ultimate Tumor Suppressor p53
Written By:
Jennifer Ellis
OCT 04, 2016
Cell & Molecular Biology
The 2016 Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi for his influential work inves
...
Written By:
Carmen Leitch
OCT 04, 2016
Neuroscience
Chronic traumatic encephalopathy (CTE) is a neurodegenerative brain disease that has gotten a lot of attention in the pr
...
Written By:
Brenda Kelley Kim
OCT 03, 2016
Cell & Molecular Biology
To put it simply, organisms inherit a copy of each gene from each parent. For a small group of genes, roughly one hundre
...
Written By:
Carmen Leitch
SEP 30, 2016
Cell & Molecular Biology
Our DNA uses messenger RNA or mRNA as the intermediary that directs cellular machinery to construct the many various pro
...
Written By:
Carmen Leitch
SEP 28, 2016
Immunology
A diet high in fat from specific sources is uniquely responsible for contributing to intestinal cancer through promoting
...
Written By:
Kara Marker
SEP 28, 2016
Cell & Molecular Biology
Every cell in our body contains DNA, and that genomic material is critical to our health. One threat to the double stran
...
Written By:
Carmen Leitch
SEP 27, 2016
Cell & Molecular Biology
Cell Regeneration in Your Eyes Could Treat Retinal Blindness Diseases
Written By:
Jennifer Ellis
SEP 27, 2016
Neuroscience
The developing brain is both a mystery and a miracle. While there is new information every day about how our brains deve
...
Written By:
Brenda Kelley Kim
SEP 25, 2016
Cell & Molecular Biology
In the natural world, genes don’t always operate independently. They can function as part of a set of genes and ca
...
Written By:
Carmen Leitch
SEP 23, 2016
Chemistry & Physics
Methanol is one of the world’s most widely used chemicals, and has been since the 1800’s. It is used to make
...
Written By:
Jennifer Ellis
SEP 22, 2016
Cell & Molecular Biology
Researchers at the Agency for Science, Technology and Research (A*STAR), Singapore, have shown that alterations in regul
...
Written By:
Carmen Leitch